Result of FASTA (omim) for
pFN21AB9909
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9909, 256 aa
1>>>pF1KB9909 256 - 256 aa - 256 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2107+/-0.000319; mu= 15.0629+/- 0.020
mean_var=73.6671+/-14.544, 0's: 0 Z-trim(117.1): 286 B-trim: 0 in 0/53
Lambda= 0.149430
statistics sampled from 28585 (28890) to 28585 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.339), width: 16
Scan time: 7.090
The best scores are: opt bits E(85289)
NP_002768 (OMIM: 177020) myeloblastin precursor [H ( 256) 1767 389.9 2.5e-108
XP_011526438 (OMIM: 177020) PREDICTED: myeloblasti ( 206) 1416 314.1 1.2e-85
XP_011526078 (OMIM: 130130,162800,202700) PREDICTE ( 267) 911 205.3 9e-53
XP_011526077 (OMIM: 130130,162800,202700) PREDICTE ( 267) 911 205.3 9e-53
NP_001963 (OMIM: 130130,162800,202700) neutrophil ( 267) 911 205.3 9e-53
NP_001691 (OMIM: 162815) azurocidin preproprotein ( 251) 657 150.5 2.6e-36
NP_001827 (OMIM: 118938) chymase isoform 1 preprop ( 247) 565 130.7 2.4e-30
NP_001902 (OMIM: 116830) cathepsin G preproprotein ( 255) 550 127.5 2.3e-29
NP_004122 (OMIM: 123910) granzyme B isoform 1 prep ( 247) 543 126.0 6.5e-29
NP_219491 (OMIM: 116831) granzyme H isoform 1 prep ( 246) 531 123.4 3.9e-28
NP_001332940 (OMIM: 123910) granzyme B isoform 2 [ ( 235) 516 120.1 3.5e-27
XP_011534801 (OMIM: 116830) PREDICTED: cathepsin G ( 269) 516 120.2 3.9e-27
NP_002762 (OMIM: 613578) trypsin-3 isoform 2 prepr ( 247) 489 114.3 2.1e-25
NP_001184027 (OMIM: 613578) trypsin-3 isoform 4 pr ( 240) 484 113.2 4.3e-25
NP_001184026 (OMIM: 613578) trypsin-3 isoform 3 pr ( 261) 484 113.3 4.6e-25
NP_031369 (OMIM: 613578) trypsin-3 isoform 1 prepr ( 304) 484 113.3 5.1e-25
XP_011516267 (OMIM: 613578) PREDICTED: trypsin-3 i ( 333) 484 113.3 5.5e-25
NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247) 475 111.3 1.7e-24
XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472) 475 111.5 2.8e-24
NP_002761 (OMIM: 167800,601564) trypsin-2 isoform ( 247) 455 107.0 3.3e-23
NP_005568 (OMIM: 152200) apolipoprotein(a) precurs (2040) 452 107.0 2.7e-22
NP_002765 (OMIM: 602652) kallikrein-6 isoform A pr ( 244) 422 99.9 4.6e-21
NP_001012982 (OMIM: 602652) kallikrein-6 isoform A ( 244) 422 99.9 4.6e-21
NP_004908 (OMIM: 204700,603767) kallikrein-4 isofo ( 254) 390 93.0 5.6e-19
NP_006135 (OMIM: 140050) granzyme A precursor [Hom ( 262) 388 92.6 7.8e-19
NP_002095 (OMIM: 600784) granzyme K precursor [Hom ( 264) 371 88.9 9.9e-18
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810) 373 89.7 1.8e-17
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263) 363 87.2 3.3e-17
NP_005308 (OMIM: 600311) granzyme M isoform 1 prep ( 257) 358 86.1 6.8e-17
NP_001257709 (OMIM: 116831) granzyme H isoform 2 p ( 182) 356 85.6 7e-17
NP_009203 (OMIM: 167800,601405) chymotrypsin-C pre ( 268) 350 84.4 2.3e-16
NP_001919 (OMIM: 134350,613912) complement factor ( 253) 349 84.2 2.6e-16
NP_009127 (OMIM: 605644) kallikrein-8 isoform 1 pr ( 260) 348 83.9 3e-16
NP_653088 (OMIM: 605644) kallikrein-8 isoform 2 pr ( 305) 345 83.3 5.4e-16
NP_001304264 (OMIM: 134350,613912) complement fact ( 260) 338 81.8 1.4e-15
NP_254275 (OMIM: 609443) chymotrypsin-like elastas ( 269) 337 81.6 1.6e-15
NP_036349 (OMIM: 609272) tryptase delta precursor ( 242) 336 81.3 1.7e-15
NP_001298111 (OMIM: 606135) kallikrein-14 prepropr ( 267) 336 81.4 1.9e-15
NP_071329 (OMIM: 606135) kallikrein-14 preproprote ( 267) 336 81.4 1.9e-15
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264) 333 80.7 2.9e-15
NP_001257710 (OMIM: 116831) granzyme H isoform 3 p ( 160) 325 78.8 6.5e-15
NP_001025218 (OMIM: 176820) prostate-specific anti ( 238) 327 79.4 6.6e-15
NP_056933 (OMIM: 609444) chymotrypsin-like elastas ( 269) 326 79.2 8.4e-15
XP_016878460 (OMIM: 610560) PREDICTED: polyserase- ( 621) 321 78.4 3.4e-14
NP_001070960 (OMIM: 605643) kallikrein-5 prepropro ( 293) 317 77.3 3.4e-14
XP_011525004 (OMIM: 605643) PREDICTED: kallikrein- ( 293) 317 77.3 3.4e-14
NP_001070959 (OMIM: 605643) kallikrein-5 prepropro ( 293) 317 77.3 3.4e-14
NP_036559 (OMIM: 605643) kallikrein-5 preproprotei ( 293) 317 77.3 3.4e-14
XP_011525005 (OMIM: 605643) PREDICTED: kallikrein- ( 293) 317 77.3 3.4e-14
XP_016878459 (OMIM: 610560) PREDICTED: polyserase- ( 634) 321 78.4 3.4e-14
>>NP_002768 (OMIM: 177020) myeloblastin precursor [Homo (256 aa)
initn: 1767 init1: 1767 opt: 1767 Z-score: 2066.0 bits: 389.9 E(85289): 2.5e-108
Smith-Waterman score: 1767; 100.0% identity (100.0% similar) in 256 aa overlap (1-256:1-256)
10 20 30 40 50 60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
190 200 210 220 230 240
250
pF1KB9 DWIRSTLRRVEAKGRP
::::::::::::::::
NP_002 DWIRSTLRRVEAKGRP
250
>>XP_011526438 (OMIM: 177020) PREDICTED: myeloblastin is (206 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1658.3 bits: 314.1 E(85289): 1.2e-85
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 206 aa overlap (1-206:1-206)
10 20 30 40 50 60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
::::::::::::::::::::::::::
XP_011 FCRPHNICTFVPRRKAGICFGDSGGP
190 200
>>XP_011526078 (OMIM: 130130,162800,202700) PREDICTED: n (267 aa)
initn: 931 init1: 762 opt: 911 Z-score: 1068.4 bits: 205.3 E(85289): 9e-53
Smith-Waterman score: 911; 54.7% identity (79.8% similar) in 247 aa overlap (10-256:12-255)
10 20 30 40 50
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGG
:: :: ::::.:.: :.:::::..:.::. :.:.:::.::. ::::.
XP_011 MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGG---HFCGA
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 TLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLND
::: :.::..::::. .. : : :::::::. .:::.: :.: ..: :.:: : :::
XP_011 TLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLND
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV
....::.. :...:.: ..::: : . . .:.:::::::: .: . :.::::::::::
XP_011 IVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 TFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
: .:: :.::.: :.::.::::::.::.:.:.:.:: ::: :::. :.:: :. ::
XP_011 TSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
180 190 200 210 220 230
240 250
pF1KB9 YVDWIRSTLRRVEAKGRP
.:.:: : ..: : . :
XP_011 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
240 250 260
>>XP_011526077 (OMIM: 130130,162800,202700) PREDICTED: n (267 aa)
initn: 931 init1: 762 opt: 911 Z-score: 1068.4 bits: 205.3 E(85289): 9e-53
Smith-Waterman score: 911; 54.7% identity (79.8% similar) in 247 aa overlap (10-256:12-255)
10 20 30 40 50
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGG
:: :: ::::.:.: :.:::::..:.::. :.:.:::.::. ::::.
XP_011 MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGG---HFCGA
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 TLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLND
::: :.::..::::. .. : : :::::::. .:::.: :.: ..: :.:: : :::
XP_011 TLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLND
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV
....::.. :...:.: ..::: : . . .:.:::::::: .: . :.::::::::::
XP_011 IVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 TFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
: .:: :.::.: :.::.::::::.::.:.:.:.:: ::: :::. :.:: :. ::
XP_011 TSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
180 190 200 210 220 230
240 250
pF1KB9 YVDWIRSTLRRVEAKGRP
.:.:: : ..: : . :
XP_011 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
240 250 260
>>NP_001963 (OMIM: 130130,162800,202700) neutrophil elas (267 aa)
initn: 931 init1: 762 opt: 911 Z-score: 1068.4 bits: 205.3 E(85289): 9e-53
Smith-Waterman score: 911; 54.7% identity (79.8% similar) in 247 aa overlap (10-256:12-255)
10 20 30 40 50
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGG
:: :: ::::.:.: :.:::::..:.::. :.:.:::.::. ::::.
NP_001 MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGG---HFCGA
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 TLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLND
::: :.::..::::. .. : : :::::::. .:::.: :.: ..: :.:: : :::
NP_001 TLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLND
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV
....::.. :...:.: ..::: : . . .:.:::::::: .: . :.::::::::::
NP_001 IVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 TFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
: .:: :.::.: :.::.::::::.::.:.:.:.:: ::: :::. :.:: :. ::
NP_001 TSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
180 190 200 210 220 230
240 250
pF1KB9 YVDWIRSTLRRVEAKGRP
.:.:: : ..: : . :
NP_001 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
240 250 260
>>NP_001691 (OMIM: 162815) azurocidin preproprotein [Hom (251 aa)
initn: 364 init1: 201 opt: 657 Z-score: 772.8 bits: 150.5 E(85289): 2.6e-36
Smith-Waterman score: 657; 43.6% identity (71.0% similar) in 241 aa overlap (9-247:8-243)
10 20 30 40 50 60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
:: . ::: .:.. .::::..:.:.. :..::.: : : :::::.:
NP_001 MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGAL
10 20 30 40 50
70 80 90 100 110
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDV
:: ::.::: :... . .:::::...: .: ..: ::.... :.:: ...:::.
NP_001 IHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT
.:.::. :::..::. . :: :. : ::.: . ::: . .. . .::::.
NP_001 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 F-FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
:::.:.:: : :..::: ::.: ::.:.:. .:. :: . :. :::::::::
NP_001 EDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVAL
180 190 200 210 220 230
240 250
pF1KB9 YVDWIRSTLRRVEAKGRP
. ::: ..:
NP_001 FRDWIDGVLNNPGPGPA
240 250
>>NP_001827 (OMIM: 118938) chymase isoform 1 preproprote (247 aa)
initn: 497 init1: 131 opt: 565 Z-score: 665.7 bits: 130.7 E(85289): 2.4e-30
Smith-Waterman score: 565; 40.4% identity (66.1% similar) in 245 aa overlap (14-248:8-245)
10 20 30 40 50
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPG-SHFCGGT
:: .:: . :.:.::.:: : .:::::::: :.. . : :.::::
NP_001 MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGF
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 LIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLND
::. .:::::::: : ..:.:::::. .: : :.. : . : . .:.. . .:
NP_001 LIRRNFVLTAAHC----AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV
..:..:. :.:. .:.:. .:.: . :: : .: . ::::.:. : ...:::... ..
NP_001 IMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 T------FFCRPHNI--CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFP
: ::. :. ::. . :::::::.: :. ::: :. : . :
NP_001 DPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSY---GRSDAKPP
180 190 200 210 220
240 250
pF1KB9 DFFTRVALYVDWIRSTLRRVEAKGRP
:::.. : :: . :.
NP_001 AVFTRISHYRPWINQILQAN
230 240
>>NP_001902 (OMIM: 116830) cathepsin G preproprotein [Ho (255 aa)
initn: 586 init1: 240 opt: 550 Z-score: 648.1 bits: 127.5 E(85289): 2.3e-29
Smith-Waterman score: 550; 39.0% identity (69.9% similar) in 246 aa overlap (13-248:6-243)
10 20 30 40 50 60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
.:::.:: .:.:.::.::.:..:::::::: ::... :. ::: :
NP_001 MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFL
10 20 30 40 50
70 80 90 100 110
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDV
.. .:::::::: . .::.:::::.. .: ::::... ... . .:. .. ::.
NP_001 VREDFVLTAAHCWGSN----INVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDI
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV--
.:.::: . . .: : ::. .. . :: : . :::::. . ...:.:... :
NP_001 MLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRG-TDTLREVQLRVQR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 ----VTFFCR--PH-NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFP
. .: :. .::. :.. . :::::::.:... .:: :. : .. . :
NP_001 DRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSY---GKSSGVPP
170 180 190 200 210 220
240 250
pF1KB9 DFFTRVALYVDWIRSTLRRVEAKGRP
. ::::. .. :::.:.:
NP_001 EVFTRVSSFLPWIRTTMRSFKLLDQMETPL
230 240 250
>>NP_004122 (OMIM: 123910) granzyme B isoform 1 prepropr (247 aa)
initn: 518 init1: 230 opt: 543 Z-score: 640.1 bits: 126.0 E(85289): 6.5e-29
Smith-Waterman score: 543; 38.7% identity (62.9% similar) in 248 aa overlap (13-249:6-246)
10 20 30 40 50 60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
.:::.:: : :.::.:::::.:::::::: :.. . . . ::: :
NP_004 MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFL
10 20 30 40 50
70 80 90 100 110
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQ-VFLNNYDAENKLNDV
:. .:::::::: .::.:::::.. :::::: . : . . :. .: ::.
NP_004 IRDDFVLTAAHCW----GSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDI
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT
.:.:: :. . .: ..::.. : : : . :::... ...:::...::
NP_004 MLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQE
110 120 130 140 150 160
180 190 200 210 220
pF1KB9 ----------FFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLF
.. ..:. :. : :::::::.:. . ::: :. : . .
NP_004 DRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSY---GRNNGMP
170 180 190 200 210 220
230 240 250
pF1KB9 PDFFTRVALYVDWIRSTLRRVEAKGRP
: :.:. .: ::..:..:
NP_004 PRACTKVSSFVHWIKKTMKRY
230 240
>>NP_219491 (OMIM: 116831) granzyme H isoform 1 prepropr (246 aa)
initn: 518 init1: 231 opt: 531 Z-score: 626.1 bits: 123.4 E(85289): 3.9e-28
Smith-Waterman score: 531; 38.2% identity (61.4% similar) in 249 aa overlap (13-250:6-246)
10 20 30 40 50 60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
.:::.::. .: . ::.:::::.:::::::: .:. . . . ::: :
NP_219 MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGIL
10 20 30 40 50
70 80 90 100 110
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQ-VFLNNYDAENKLNDV
.. .:::::::: .::.:::::.. :: ::: . : . . :. .: ::.
NP_219 VRKDFVLTAAHC----QGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDI
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT
.:.:: :. ...: ..::.. : : : . ::: : . . : .:::. .::
NP_219 MLLQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQK
110 120 130 140 150 160
180 190 200 210 220
pF1KB9 -------F---FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLF
: . : .::. :.. :::::::.: . ::: :. :
NP_219 DCQCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSY---GNKKGTP
170 180 190 200 210 220
230 240 250
pF1KB9 PDFFTRVALYVDWIRSTLRRVEAKGRP
: . .:. .. ::. :..:.
NP_219 PGVYIKVSHFLPWIKRTMKRL
230 240
256 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:48:26 2016 done: Sat Nov 5 14:48:27 2016
Total Scan time: 7.090 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]