Result of FASTA (omim) for
pFN21AB6629
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6629, 415 aa
1>>>pF1KB6629 415 - 415 aa - 415 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7737+/-0.00054; mu= -1.7819+/- 0.033
mean_var=705.6372+/-169.710, 0's: 0 Z-trim(117.1): 104 B-trim: 1679 in 1/54
Lambda= 0.048282
statistics sampled from 28694 (28797) to 28694 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.338), width: 16
Scan time: 8.960
The best scores are: opt bits E(85289)
NP_001884 (OMIM: 600864,615224) casein kinase I is ( 415) 2777 209.2 1.5e-53
XP_005256393 (OMIM: 600864,615224) PREDICTED: case ( 450) 2684 202.8 1.4e-51
XP_005256394 (OMIM: 600864,615224) PREDICTED: case ( 427) 2677 202.3 1.9e-51
NP_620693 (OMIM: 600864,615224) casein kinase I is ( 409) 2676 202.2 2e-51
XP_016879688 (OMIM: 600864,615224) PREDICTED: case ( 393) 2312 176.8 8.2e-44
NP_001885 (OMIM: 600863) casein kinase I isoform e ( 416) 2309 176.7 9.8e-44
NP_689407 (OMIM: 600863) casein kinase I isoform e ( 416) 2309 176.7 9.8e-44
NP_001258670 (OMIM: 600505) casein kinase I isofor ( 325) 1573 125.2 2.4e-28
NP_001883 (OMIM: 600505) casein kinase I isoform a ( 337) 1573 125.2 2.4e-28
XP_005271953 (OMIM: 604253) PREDICTED: casein kina ( 416) 1227 101.3 4.8e-21
NP_001257501 (OMIM: 604253) casein kinase I isofor ( 424) 1223 101.0 5.8e-21
XP_005271952 (OMIM: 604253) PREDICTED: casein kina ( 424) 1223 101.0 5.8e-21
XP_016864558 (OMIM: 604253) PREDICTED: casein kina ( 424) 1223 101.0 5.8e-21
XP_016864559 (OMIM: 604253) PREDICTED: casein kina ( 415) 1216 100.5 8.1e-21
XP_005271948 (OMIM: 604253) PREDICTED: casein kina ( 456) 1214 100.4 9.3e-21
NP_001026982 (OMIM: 604253) casein kinase I isofor ( 423) 1212 100.3 9.9e-21
NP_001310 (OMIM: 602214) casein kinase I isoform g ( 415) 1208 100.0 1.2e-20
XP_005271951 (OMIM: 604253) PREDICTED: casein kina ( 447) 1203 99.7 1.6e-20
NP_004375 (OMIM: 604253) casein kinase I isoform g ( 447) 1203 99.7 1.6e-20
XP_005271949 (OMIM: 604253) PREDICTED: casein kina ( 455) 1203 99.7 1.6e-20
NP_001038188 (OMIM: 604253) casein kinase I isofor ( 455) 1203 99.7 1.6e-20
NP_001316534 (OMIM: 606274) casein kinase I isofor ( 475) 1203 99.7 1.6e-20
XP_005259557 (OMIM: 602214) PREDICTED: casein kina ( 440) 1199 99.4 1.9e-20
NP_071331 (OMIM: 606274) casein kinase I isoform g ( 422) 1190 98.7 2.9e-20
NP_001316535 (OMIM: 606274) casein kinase I isofor ( 422) 1190 98.7 2.9e-20
NP_001316536 (OMIM: 606274) casein kinase I isofor ( 438) 1190 98.7 2.9e-20
XP_016864556 (OMIM: 604253) PREDICTED: casein kina ( 441) 1143 95.5 2.8e-19
XP_016864553 (OMIM: 604253) PREDICTED: casein kina ( 449) 1139 95.2 3.5e-19
XP_016864557 (OMIM: 604253) PREDICTED: casein kina ( 440) 1132 94.7 4.8e-19
XP_016864552 (OMIM: 604253) PREDICTED: casein kina ( 473) 1130 94.6 5.5e-19
XP_016864548 (OMIM: 604253) PREDICTED: casein kina ( 481) 1130 94.6 5.5e-19
XP_016864546 (OMIM: 604253) PREDICTED: casein kina ( 481) 1130 94.6 5.5e-19
XP_016864549 (OMIM: 604253) PREDICTED: casein kina ( 481) 1130 94.6 5.5e-19
XP_016864547 (OMIM: 604253) PREDICTED: casein kina ( 481) 1130 94.6 5.5e-19
XP_016864555 (OMIM: 604253) PREDICTED: casein kina ( 448) 1128 94.4 5.9e-19
XP_016864554 (OMIM: 604253) PREDICTED: casein kina ( 448) 1128 94.4 5.9e-19
XP_016881787 (OMIM: 602214) PREDICTED: casein kina ( 367) 1122 93.9 7.2e-19
XP_016864550 (OMIM: 604253) PREDICTED: casein kina ( 480) 1119 93.9 9.4e-19
XP_016864551 (OMIM: 604253) PREDICTED: casein kina ( 480) 1119 93.9 9.4e-19
XP_005259558 (OMIM: 602214) PREDICTED: casein kina ( 392) 1113 93.3 1.1e-18
NP_001257502 (OMIM: 604253) casein kinase I isofor ( 348) 1084 91.2 4.4e-18
XP_005259556 (OMIM: 602214) PREDICTED: casein kina ( 445) 1015 86.6 1.4e-16
XP_016881786 (OMIM: 602214) PREDICTED: casein kina ( 445) 1015 86.6 1.4e-16
XP_005259555 (OMIM: 602214) PREDICTED: casein kina ( 445) 1015 86.6 1.4e-16
NP_001257503 (OMIM: 604253) casein kinase I isofor ( 311) 974 83.4 8.4e-16
NP_001258671 (OMIM: 600505) casein kinase I isofor ( 276) 848 74.6 3.5e-13
NP_001020276 (OMIM: 600505) casein kinase I isofor ( 365) 848 74.8 4e-13
NP_775771 (OMIM: 604432,611695) tau-tubulin kinase (1244) 581 57.1 2.8e-07
XP_006720465 (OMIM: 604432,611695) PREDICTED: tau- (1239) 462 48.8 8.8e-05
XP_005254228 (OMIM: 604432,611695) PREDICTED: tau- (1250) 462 48.8 8.8e-05
>>NP_001884 (OMIM: 600864,615224) casein kinase I isofor (415 aa)
initn: 2777 init1: 2777 opt: 2777 Z-score: 1082.4 bits: 209.2 E(85289): 1.5e-53
Smith-Waterman score: 2777; 100.0% identity (100.0% similar) in 415 aa overlap (1-415:1-415)
10 20 30 40 50 60
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
370 380 390 400 410
>>XP_005256393 (OMIM: 600864,615224) PREDICTED: casein k (450 aa)
initn: 2679 init1: 2679 opt: 2684 Z-score: 1047.1 bits: 202.8 E(85289): 1.4e-51
Smith-Waterman score: 2684; 97.8% identity (98.3% similar) in 412 aa overlap (1-408:1-412)
10 20 30 40 50 60
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQI----PGRVASSGLQSVVHR
:::::::::::::::::::::::::::::::::::::::. :: .::
XP_005 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQVGAELPGGRWASGYPVRVKSG
370 380 390 400 410 420
XP_005 LWFLQGFFFPFFPPFLRVFNLARVWRLGCR
430 440 450
>>XP_005256394 (OMIM: 600864,615224) PREDICTED: casein k (427 aa)
initn: 2676 init1: 2676 opt: 2677 Z-score: 1044.6 bits: 202.3 E(85289): 1.9e-51
Smith-Waterman score: 2677; 97.8% identity (98.5% similar) in 411 aa overlap (1-411:1-411)
10 20 30 40 50 60
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
::::::::::::::::::::::::::::::::::::::: .:: :..
XP_005 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQRSRDMASLRLHAARQGTRCRP
370 380 390 400 410 420
XP_005 QRPRRTY
>>NP_620693 (OMIM: 600864,615224) casein kinase I isofor (409 aa)
initn: 2675 init1: 2675 opt: 2676 Z-score: 1044.4 bits: 202.2 E(85289): 2e-51
Smith-Waterman score: 2676; 99.5% identity (99.5% similar) in 403 aa overlap (1-401:1-403)
10 20 30 40 50 60
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQ--IPGRVASSGLQSVVHR
::::::::::::::::::::::::::::::::::::::: ::
NP_620 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQNSIPFEHHGK
370 380 390 400
>>XP_016879688 (OMIM: 600864,615224) PREDICTED: casein k (393 aa)
initn: 2307 init1: 2307 opt: 2312 Z-score: 907.5 bits: 176.8 E(85289): 8.2e-44
Smith-Waterman score: 2312; 97.5% identity (98.0% similar) in 355 aa overlap (58-408:1-355)
30 40 50 60 70 80
pF1KB6 DIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGP
::::::::::::::::::::::::::::::
XP_016 MMQGGVGIPTIRWCGAEGDYNVMVMELLGP
10 20 30
90 100 110 120 130 140
pF1KB6 SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYI
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 IDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFN
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 LGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB6 YLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLP
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB6 STASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLT
280 290 300 310 320 330
390 400 410
pF1KB6 GRQDTSRMSTSQI----PGRVASSGLQSVVHR
::::::::::::. :: .::
XP_016 GRQDTSRMSTSQVGAELPGGRWASGYPVRVKSGLWFLQGFFFPFFPPFLRVFNLARVWRL
340 350 360 370 380 390
>>NP_001885 (OMIM: 600863) casein kinase I isoform epsil (416 aa)
initn: 2032 init1: 2032 opt: 2309 Z-score: 906.2 bits: 176.7 E(85289): 9.8e-44
Smith-Waterman score: 2309; 85.0% identity (94.3% similar) in 406 aa overlap (1-399:1-406)
10 20 30 40 50 60
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
:::::::.::::::::::::::::::..::.:::::::::::::::::::::::.:::::
NP_001 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
::::::::.::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 ADDAERERRD--REERLRHSRNPATRGLP-----STASGRLRGTQEVAPPTPLTPTSHTA
.:..::::. ::::. . :. :::.:: .....:::.. : . :: . . ..
NP_001 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 NTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVV
::::: .: ..::::::::::::::.:.:::::::::..::. .::
NP_001 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
370 380 390 400 410
pF1KB6 HR
>>NP_689407 (OMIM: 600863) casein kinase I isoform epsil (416 aa)
initn: 2032 init1: 2032 opt: 2309 Z-score: 906.2 bits: 176.7 E(85289): 9.8e-44
Smith-Waterman score: 2309; 85.0% identity (94.3% similar) in 406 aa overlap (1-399:1-406)
10 20 30 40 50 60
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
:::::::.::::::::::::::::::..::.:::::::::::::::::::::::.:::::
NP_689 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
::::::::.::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_689 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 ADDAERERRD--REERLRHSRNPATRGLP-----STASGRLRGTQEVAPPTPLTPTSHTA
.:..::::. ::::. . :. :::.:: .....:::.. : . :: . . ..
NP_689 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB6 NTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVV
::::: .: ..::::::::::::::.:.:::::::::..::. .::
NP_689 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
370 380 390 400 410
pF1KB6 HR
>>NP_001258670 (OMIM: 600505) casein kinase I isoform al (325 aa)
initn: 1568 init1: 1568 opt: 1573 Z-score: 630.0 bits: 125.2 E(85289): 2.4e-28
Smith-Waterman score: 1573; 75.0% identity (91.0% similar) in 300 aa overlap (2-301:10-309)
10 20 30 40 50
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
:. ::..:.: :::::::::::::. .:. :::::.::: :..:::: :
NP_001 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
::.::..::::::: ::: : : ::::.::.:::::::::::::::.:..::::.:::::
NP_001 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
NP_001 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
NP_001 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_001 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
:: :.. :
NP_001 LKQKAAQQAASSSGQGQQAQTPTGF
310 320
>>NP_001883 (OMIM: 600505) casein kinase I isoform alpha (337 aa)
initn: 1568 init1: 1568 opt: 1573 Z-score: 629.9 bits: 125.2 E(85289): 2.4e-28
Smith-Waterman score: 1573; 75.0% identity (91.0% similar) in 300 aa overlap (2-301:10-309)
10 20 30 40 50
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
:. ::..:.: :::::::::::::. .:. :::::.::: :..:::: :
NP_001 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
::.::..::::::: ::: : : ::::.::.:::::::::::::::.:..::::.:::::
NP_001 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
NP_001 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
NP_001 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_001 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
:: :.. :
NP_001 LKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
310 320 330
>>XP_005271953 (OMIM: 604253) PREDICTED: casein kinase I (416 aa)
initn: 1206 init1: 667 opt: 1227 Z-score: 498.9 bits: 101.3 E(85289): 4.8e-21
Smith-Waterman score: 1227; 49.5% identity (77.6% similar) in 384 aa overlap (3-375:37-416)
10 20 30
pF1KB6 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAG
: :: .:.:.::: :.::.. :: .. ..
XP_005 DKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 EEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDL
: :::::: .:.. ::::.: ..::.. .: ::: . . : : ::.::.::::::::::
XP_005 EYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 FNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDF
:..:.: :::::::..: :.:::.::.::::.:.:::::.:::.: .: ....::::
XP_005 FDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 GLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGS
::::.: : .:..::::::.:.::::::: ::::::: :::::::::.::...::: ::
XP_005 GLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 LPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLR
:::::::: : ...:..:.. : .:::::::...: :.:::: . : : : .::::.:::
XP_005 LPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLR
250 260 270 280 290 300
280 290 300 310 320
pF1KB6 QLFRNLFHRQGFSYDYVFDWNMLKF----GASRA--ADDAERERRDREERLRHSRNPATR
.:: .:: :.:. .:: .:: .. :: . : ...:: .........:.: ..
XP_005 KLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQVV-
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB6 GLPSTASGRLRGTQEVAPPT--PLT-PTSHTANTSPRPVSGMERERKVSMRLHRGAPVNI
:...:.: . .: . :.: :: . . ..:... ... :.
XP_005 ---SSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRHK
370 380 390 400 410
390 400 410
pF1KB6 SSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
415 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:36:40 2016 done: Sat Nov 5 11:36:41 2016
Total Scan time: 8.960 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]