Result of FASTA (omim) for
pFN21AB7955
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7955, 256 aa
1>>>pF1KB7955 256 - 256 aa - 256 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6737+/-0.000346; mu= 18.1086+/- 0.022
mean_var=58.9190+/-11.827, 0's: 0 Z-trim(113.9): 14 B-trim: 42 in 1/52
Lambda= 0.167088
statistics sampled from 23399 (23413) to 23399 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.275), width: 16
Scan time: 6.080
The best scores are: opt bits E(85289)
NP_006784 (OMIM: 604769) thioredoxin-dependent per ( 256) 1701 418.1 7.6e-117
NP_001289201 (OMIM: 604769) thioredoxin-dependent ( 198) 1214 300.6 1.4e-81
XP_005274495 (OMIM: 300927) PREDICTED: peroxiredox ( 257) 912 227.9 1.4e-59
NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor ( 271) 911 227.7 1.7e-59
NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sap ( 198) 881 220.4 2e-57
NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 876 219.2 4.6e-57
NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 876 219.2 4.6e-57
NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo ( 199) 876 219.2 4.6e-57
NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 876 219.2 4.6e-57
XP_016884720 (OMIM: 300927) PREDICTED: peroxiredox ( 336) 861 215.7 8.4e-56
XP_016884719 (OMIM: 300927) PREDICTED: peroxiredox ( 350) 860 215.5 1e-55
NP_004896 (OMIM: 602316) peroxiredoxin-6 [Homo sap ( 224) 156 45.6 8.9e-05
NP_036226 (OMIM: 606583) peroxiredoxin-5, mitochon ( 214) 141 42.0 0.001
>>NP_006784 (OMIM: 604769) thioredoxin-dependent peroxid (256 aa)
initn: 1701 init1: 1701 opt: 1701 Z-score: 2218.8 bits: 418.1 E(85289): 7.6e-117
Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 256 aa overlap (1-256:1-256)
10 20 30 40 50 60
pF1KB7 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
190 200 210 220 230 240
250
pF1KB7 KPSPAASKEYFQKVNQ
::::::::::::::::
NP_006 KPSPAASKEYFQKVNQ
250
>>NP_001289201 (OMIM: 604769) thioredoxin-dependent pero (198 aa)
initn: 1214 init1: 1214 opt: 1214 Z-score: 1585.9 bits: 300.6 E(85289): 1.4e-81
Smith-Waterman score: 1214; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB7 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
::::
NP_001 LALRSSQVQLLPKSTFRR
190
>>XP_005274495 (OMIM: 300927) PREDICTED: peroxiredoxin-4 (257 aa)
initn: 905 init1: 905 opt: 912 Z-score: 1190.8 bits: 227.9 E(85289): 1.4e-59
Smith-Waterman score: 912; 67.0% identity (90.6% similar) in 191 aa overlap (65-255:67-257)
40 50 60 70 80 90
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
:.. :::..::::..::::.:.: :..:::
XP_005 EGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVIDGEFKELKLTDYRGKY
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB7 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
::.:::::::::::::::.::.:. .::...: :::: ::::.:.:::::::::..::::
XP_005 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB7 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
. : ::::::.:::.:::: :: :: .:::::::: .:.......:::::::::.::::
XP_005 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
160 170 180 190 200 210
220 230 240 250
pF1KB7 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
::.::::.. :::::::.: : : :: :.::.. .::.:.:
XP_005 LVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
220 230 240 250
>>NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor [Ho (271 aa)
initn: 924 init1: 905 opt: 911 Z-score: 1189.2 bits: 227.7 E(85289): 1.7e-59
Smith-Waterman score: 911; 66.5% identity (90.6% similar) in 191 aa overlap (65-255:81-271)
40 50 60 70 80 90
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
... :::..::::..::::.:.: :..:::
NP_006 CHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKY
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB7 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
::.:::::::::::::::.::.:. .::...: :::: ::::.:.:::::::::..::::
NP_006 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
. : ::::::.:::.:::: :: :: .:::::::: .:.......:::::::::.::::
NP_006 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
180 190 200 210 220 230
220 230 240 250
pF1KB7 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
::.::::.. :::::::.: : : :: :.::.. .::.:.:
NP_006 LVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
240 250 260 270
>>NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sapiens (198 aa)
initn: 879 init1: 879 opt: 881 Z-score: 1152.0 bits: 220.4 E(85289): 2e-57
Smith-Waterman score: 881; 65.4% identity (89.0% similar) in 191 aa overlap (65-255:8-198)
40 50 60 70 80 90
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
. . :: ::.::::.: ::...:.:.::::
NP_005 MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKY
10 20 30
100 110 120 130 140 150
pF1KB7 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
.:::::::::::::::::.:::..:..:. ..:::..:::::.:.::::::::::.::::
NP_005 VVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLG
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB7 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
.:: ::.:.:...:.::::: :.: ::::::: .::.....::::::::::.:.::
NP_005 PLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALR
100 110 120 130 140 150
220 230 240 250
pF1KB7 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
::.::::.. :::::::.: : : ::::. :::::.: :
NP_005 LVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN
160 170 180 190
>>NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 862 init1: 832 opt: 876 Z-score: 1145.5 bits: 219.2 E(85289): 4.6e-57
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (65-253:8-197)
40 50 60 70 80 90
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
. . :: ::.:::. .:.:::.::.:.:::
NP_859 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
10 20 30
100 110 120 130 140 150
pF1KB7 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
:.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_859 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB7 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
: ::: :.:: . :..::::: :...::::::: .:......::::::::::.:::
NP_859 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
100 110 120 130 140 150
220 230 240 250
pF1KB7 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
:::.:::... :::::::.: : : ::::. :::::.:
NP_859 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
160 170 180 190
>>NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 862 init1: 832 opt: 876 Z-score: 1145.5 bits: 219.2 E(85289): 4.6e-57
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (65-253:8-197)
40 50 60 70 80 90
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
. . :: ::.:::. .:.:::.::.:.:::
NP_002 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
10 20 30
100 110 120 130 140 150
pF1KB7 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
:.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_002 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB7 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
: ::: :.:: . :..::::: :...::::::: .:......::::::::::.:::
NP_002 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
100 110 120 130 140 150
220 230 240 250
pF1KB7 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
:::.:::... :::::::.: : : ::::. :::::.:
NP_002 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
160 170 180 190
>>NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo sapi (199 aa)
initn: 862 init1: 832 opt: 876 Z-score: 1145.5 bits: 219.2 E(85289): 4.6e-57
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (65-253:8-197)
40 50 60 70 80 90
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
. . :: ::.:::. .:.:::.::.:.:::
NP_001 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
10 20 30
100 110 120 130 140 150
pF1KB7 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
:.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_001 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB7 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
: ::: :.:: . :..::::: :...::::::: .:......::::::::::.:::
NP_001 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
100 110 120 130 140 150
220 230 240 250
pF1KB7 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
:::.:::... :::::::.: : : ::::. :::::.:
NP_001 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
160 170 180 190
>>NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 862 init1: 832 opt: 876 Z-score: 1145.5 bits: 219.2 E(85289): 4.6e-57
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (65-253:8-197)
40 50 60 70 80 90
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
. . :: ::.:::. .:.:::.::.:.:::
NP_859 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
10 20 30
100 110 120 130 140 150
pF1KB7 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
:.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_859 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB7 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
: ::: :.:: . :..::::: :...::::::: .:......::::::::::.:::
NP_859 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
100 110 120 130 140 150
220 230 240 250
pF1KB7 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
:::.:::... :::::::.: : : ::::. :::::.:
NP_859 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
160 170 180 190
>>XP_016884720 (OMIM: 300927) PREDICTED: peroxiredoxin-4 (336 aa)
initn: 854 init1: 854 opt: 861 Z-score: 1122.8 bits: 215.7 E(85289): 8.4e-56
Smith-Waterman score: 861; 68.2% identity (90.9% similar) in 176 aa overlap (65-240:67-242)
40 50 60 70 80 90
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
:.. :::..::::..::::.:.: :..:::
XP_016 EGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVIDGEFKELKLTDYRGKY
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB7 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
::.:::::::::::::::.::.:. .::...: :::: ::::.:.:::::::::..::::
XP_016 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
100 110 120 130 140 150
160 170 180 190 200 210
pF1KB7 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
. : ::::::.:::.:::: :: :: .:::::::: .:.......:::::::::.::::
XP_016 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
160 170 180 190 200 210
220 230 240 250
pF1KB7 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
::.::::.. :::::::.: : : :.
XP_016 LVQAFQYTDKHGEVCPAGWKPGSETVSIYICFYVELMVRVEKNAGRAQWLTPVIPALWEA
220 230 240 250 260 270
256 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:16:33 2016 done: Sat Nov 5 10:16:34 2016
Total Scan time: 6.080 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]