Result of FASTA (omim) for
pFN21AB9852
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9852, 382 aa
1>>>pF1KB9852 382 - 382 aa - 382 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7317+/-0.000318; mu= 15.4452+/- 0.020
mean_var=83.8728+/-16.419, 0's: 0 Z-trim(117.1): 47 B-trim: 359 in 1/54
Lambda= 0.140044
statistics sampled from 28682 (28729) to 28682 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.337), width: 16
Scan time: 9.020
The best scores are: opt bits E(85289)
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 2573 529.4 5.4e-150
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 995 210.5 4.5e-54
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 995 210.5 4.5e-54
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 995 210.5 4.5e-54
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 942 199.9 9.4e-51
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 942 199.9 9.4e-51
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 900 191.4 3.3e-48
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 900 191.4 3.4e-48
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 900 191.4 3.4e-48
NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 883 187.9 3.1e-47
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 883 187.9 3.1e-47
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 883 187.9 3.1e-47
NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 883 187.9 3.1e-47
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 847 180.8 6.7e-45
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 832 177.7 5.3e-44
NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 436 97.5 3.8e-20
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 436 97.5 3.8e-20
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 433 96.9 5e-20
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 433 96.9 5e-20
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 426 95.5 1.6e-19
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 426 95.5 1.6e-19
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 426 95.5 1.6e-19
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 426 95.5 1.6e-19
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 413 92.9 9.3e-19
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 413 92.9 9.3e-19
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 413 92.9 9.3e-19
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 413 92.9 9.3e-19
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 413 92.9 9.3e-19
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 413 92.9 9.3e-19
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 413 92.9 9.3e-19
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 413 92.9 9.3e-19
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 407 91.7 2.2e-18
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 407 91.7 2.2e-18
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 405 91.4 4e-18
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 405 91.4 4e-18
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 405 91.4 4e-18
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 405 91.4 4e-18
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 392 88.7 1.8e-17
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 392 88.7 1.8e-17
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 390 88.2 2.1e-17
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 390 88.2 2.1e-17
NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 385 87.4 7.1e-17
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 367 83.6 6.4e-16
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 358 81.8 2.4e-15
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 328 75.7 1.4e-13
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 313 72.7 1.2e-12
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 259 61.9 2.9e-09
>>NP_000156 (OMIM: 104100,121014,133200,164200,186100,21 (382 aa)
initn: 2573 init1: 2573 opt: 2573 Z-score: 2813.9 bits: 529.4 E(85289): 5.4e-150
Smith-Waterman score: 2573; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 YNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVD
310 320 330 340 350 360
370 380
pF1KB9 QRPSSRASSRASSRPRPDDLEI
::::::::::::::::::::::
NP_000 QRPSSRASSRASSRPRPDDLEI
370 380
>>XP_005270807 (OMIM: 121012) PREDICTED: gap junction al (333 aa)
initn: 1039 init1: 967 opt: 995 Z-score: 1091.7 bits: 210.5 E(85289): 4.5e-54
Smith-Waterman score: 1024; 45.6% identity (69.3% similar) in 375 aa overlap (1-370:1-330)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::. : ::::.:: .::. ::.::.::::::::.:: : ::.:::::: :.::: :::
XP_005 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
: :::::..:::::.:.::::..:::.:::.::.::.:. :.::.: .:: ::.. .
XP_005 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
.:. : .: . : .. : :....::.:. ::. :.: ::..:..:: :: .::..
XP_005 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
130 140 150 160 170 180
190 200 210 220 230
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
. :..:.: :::. ::::.::::::::::::::::.:.::.::..:: ... . :.
XP_005 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS
. : . : ..::. .: : : . :. :.. .: :::
XP_005 RARQGQDAPPTQGTSS--DPYTD---QVFFYL-----PVGQ-GPSSPP------------
250 260 270
300 310 320 330 340 350
pF1KB9 SCRNYNK-QASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQP
: .:: ..::::::: ..:. :.. : :. . ::..: :
XP_005 -CPTYNGLSSSEQNWANLTTEE-RLA--------SSRPPLFLDPPPQNGQK--------P
280 290 300 310
360 370 380
pF1KB9 LAIVDQRPSSRASSRASSRPRPDDLEI
.:::: ::..
XP_005 ----PSRPSSSASKKQYV
320 330
>>XP_016856532 (OMIM: 121012) PREDICTED: gap junction al (333 aa)
initn: 1039 init1: 967 opt: 995 Z-score: 1091.7 bits: 210.5 E(85289): 4.5e-54
Smith-Waterman score: 1024; 45.6% identity (69.3% similar) in 375 aa overlap (1-370:1-330)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::. : ::::.:: .::. ::.::.::::::::.:: : ::.:::::: :.::: :::
XP_016 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
: :::::..:::::.:.::::..:::.:::.::.::.:. :.::.: .:: ::.. .
XP_016 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
.:. : .: . : .. : :....::.:. ::. :.: ::..:..:: :: .::..
XP_016 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
130 140 150 160 170 180
190 200 210 220 230
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
. :..:.: :::. ::::.::::::::::::::::.:.::.::..:: ... . :.
XP_016 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS
. : . : ..::. .: : : . :. :.. .: :::
XP_016 RARQGQDAPPTQGTSS--DPYTD---QVFFYL-----PVGQ-GPSSPP------------
250 260 270
300 310 320 330 340 350
pF1KB9 SCRNYNK-QASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQP
: .:: ..::::::: ..:. :.. : :. . ::..: :
XP_016 -CPTYNGLSSSEQNWANLTTEE-RLA--------SSRPPLFLDPPPQNGQK--------P
280 290 300 310
360 370 380
pF1KB9 LAIVDQRPSSRASSRASSRPRPDDLEI
.:::: ::..
XP_016 ----PSRPSSSASKKQYV
320 330
>>NP_002051 (OMIM: 121012) gap junction alpha-4 protein (333 aa)
initn: 1039 init1: 967 opt: 995 Z-score: 1091.7 bits: 210.5 E(85289): 4.5e-54
Smith-Waterman score: 1024; 45.6% identity (69.3% similar) in 375 aa overlap (1-370:1-330)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::. : ::::.:: .::. ::.::.::::::::.:: : ::.:::::: :.::: :::
NP_002 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
: :::::..:::::.:.::::..:::.:::.::.::.:. :.::.: .:: ::.. .
NP_002 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
.:. : .: . : .. : :....::.:. ::. :.: ::..:..:: :: .::..
NP_002 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
130 140 150 160 170 180
190 200 210 220 230
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
. :..:.: :::. ::::.::::::::::::::::.:.::.::..:: ... . :.
NP_002 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS
. : . : ..::. .: : : . :. :.. .: :::
NP_002 RARQGQDAPPTQGTSS--DPYTD---QVFFYL-----PVGQ-GPSSPP------------
250 260 270
300 310 320 330 340 350
pF1KB9 SCRNYNK-QASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQP
: .:: ..::::::: ..:. :.. : :. . ::..: :
NP_002 -CPTYNGLSSSEQNWANLTTEE-RLA--------SSRPPLFLDPPPQNGQK--------P
280 290 300 310
360 370 380
pF1KB9 LAIVDQRPSSRASSRASSRPRPDDLEI
.:::: ::..
NP_002 ----PSRPSSSASKKQYV
320 330
>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc (435 aa)
initn: 1117 init1: 583 opt: 942 Z-score: 1032.2 bits: 199.9 E(85289): 9.4e-51
Smith-Waterman score: 985; 42.2% identity (67.2% similar) in 412 aa overlap (1-382:1-398)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::: ::.::...: .::. :::::.::::::::.::.:.:..:::::: : :::::::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
:::::::..:::::.:::.:::::::.:::.::.::....: ::: ...::: .. . .
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
. . . ...:.:.: :.:::::...:.::..:::.:. :...:::
XP_011 SPKEPPQDNPSSR------DDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFE
130 140 150 160 170
190 200 210 220 230
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
:. .: : : :::. ::::.::::::::::::::.:. .:: ::..:.... .: ::
XP_011 LKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV
180 190 200 210 220 230
240 250 260 270 280
pF1KB9 KDRVK--------GKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLS----PMSPP
.:. : .:: .. :: : : . ..: . : .::
XP_011 TSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPY--YAHTAAPLGQARAVGYPGAPP
240 250 260 270 280 290
290 300 310 320 330
pF1KB9 ---GYKLV--TGDRNNS-SCRNYNKQ----ASEQNWANYSAEQNRMGQAGSTISNSHAQP
.::. : :... : . :: . .:::::: .::.. . . ... : :
XP_011 PAADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAP
300 310 320 330 340 350
340 350 360 370 380
pF1KB9 FDFPDDNQNSKKLAAGHELQ----PLAIVDQRPSSRASSRASSRPRPDDLEI
...: :: :: . :: ..: :: .: .. :. .. .
XP_011 SPV---GSSSPPLA--HEAEAGAAPL-LLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ
360 370 380 390 400
XP_011 PPLPLGDPGRASKASRASSGRARPEDLAI
410 420 430
>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p (435 aa)
initn: 1117 init1: 583 opt: 942 Z-score: 1032.2 bits: 199.9 E(85289): 9.4e-51
Smith-Waterman score: 985; 42.2% identity (67.2% similar) in 412 aa overlap (1-382:1-398)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::: ::.::...: .::. :::::.::::::::.::.:.:..:::::: : :::::::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
:::::::..:::::.:::.:::::::.:::.::.::....: ::: ...::: .. . .
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
. . . ...:.:.: :.:::::...:.::..:::.:. :...:::
NP_068 SPKEPPQDNPSSR------DDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFE
130 140 150 160 170
190 200 210 220 230
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV
:. .: : : :::. ::::.::::::::::::::.:. .:: ::..:.... .: ::
NP_068 LKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV
180 190 200 210 220 230
240 250 260 270 280
pF1KB9 KDRVK--------GKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLS----PMSPP
.:. : .:: .. :: : : . ..: . : .::
NP_068 TSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPY--YAHTAAPLGQARAVGYPGAPP
240 250 260 270 280 290
290 300 310 320 330
pF1KB9 ---GYKLV--TGDRNNS-SCRNYNKQ----ASEQNWANYSAEQNRMGQAGSTISNSHAQP
.::. : :... : . :: . .:::::: .::.. . . ... : :
NP_068 PAADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAP
300 310 320 330 340 350
340 350 360 370 380
pF1KB9 FDFPDDNQNSKKLAAGHELQ----PLAIVDQRPSSRASSRASSRPRPDDLEI
...: :: :: . :: ..: :: .: .. :. .. .
NP_068 SPV---GSSSPPLA--HEAEAGAAPL-LLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ
360 370 380 390 400
NP_068 PPLPLGDPGRASKASRASSGRARPEDLAI
410 420 430
>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g (427 aa)
initn: 918 init1: 544 opt: 900 Z-score: 986.4 bits: 191.4 E(85289): 3.3e-48
Smith-Waterman score: 900; 55.2% identity (81.3% similar) in 241 aa overlap (1-241:1-237)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::: ::..:..:. .::. :.:::.::::::::.::::.: .:::::: : :::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
:::::::..:::::.:.:::::::::.:.:.:..:. . .: ::: ...: : ...: :
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE-ELGQQAG
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
.: : .:: . : . : ...: :::::: :.::..:::.:.. ....:::
XP_011 TNGGP--DQGSVKK-SSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
. .: :.: :::. ::::.::::::::::.::: :. ::: ::..:: .. .::... .
XP_011 ILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
:
XP_011 KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKP
240 250 260 270 280 290
>>NP_005258 (OMIM: 116200,600897,612474) gap junction al (433 aa)
initn: 959 init1: 544 opt: 900 Z-score: 986.3 bits: 191.4 E(85289): 3.4e-48
Smith-Waterman score: 900; 55.2% identity (81.3% similar) in 241 aa overlap (1-241:1-237)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::: ::..:..:. .::. :.:::.::::::::.::::.: .:::::: : :::::::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
:::::::..:::::.:.:::::::::.:.:.:..:. . .: ::: ...: : ...: :
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE-ELGQQAG
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
.: : .:: . : . : ...: :::::: :.::..:::.:.. ....:::
NP_005 TNGGP--DQGSVKK-SSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
. .: :.: :::. ::::.::::::::::.::: :. ::: ::..:: .. .::... .
NP_005 ILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
:
NP_005 KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKP
240 250 260 270 280 290
>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g (433 aa)
initn: 959 init1: 544 opt: 900 Z-score: 986.3 bits: 191.4 E(85289): 3.4e-48
Smith-Waterman score: 900; 55.2% identity (81.3% similar) in 241 aa overlap (1-241:1-237)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::: ::..:..:. .::. :.:::.::::::::.::::.: .:::::: : :::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG
:::::::..:::::.:.:::::::::.:.:.:..:. . .: ::: ...: : ...: :
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE-ELGQQAG
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS
.: : .:: . : . : ...: :::::: :.::..:::.:.. ....:::
XP_011 TNGGP--DQGSVKK-SSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV
. .: :.: :::. ::::.::::::::::.::: :. ::: ::..:: .. .::... .
XP_011 ILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 KGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRN
:
XP_011 KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKP
240 250 260 270 280 290
>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc (358 aa)
initn: 938 init1: 538 opt: 883 Z-score: 969.0 bits: 187.9 E(85289): 3.1e-47
Smith-Waterman score: 921; 40.6% identity (69.9% similar) in 389 aa overlap (1-382:1-358)
10 20 30 40 50 60
pF1KB9 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG
::::: ::..:..:. .::. :::::.::::::.:.::::.::.:::::. :::.: :::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKE-EELKVAQTD
:.:::::..:::::.:.:::::::::.:.:.:..:.....: .:: . .: :. : .. .
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 GVNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGF
: .. :.. .. : .:.. ..: :: ::. :::... .::.:.. :..:::.
NP_859 GSYEYPVAEKAELSCWEEG---NGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGI
130 140 150 160 170
180 190 200 210 220 230
pF1KB9 SLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDR
:.....:.:.:::: :.:..::::::..::.:::.:. .:: :.. ::... .: ...:
NP_859 FLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 -VKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPM-SPPGYKLVTGDRNNSS
:: .. : .. :: . . . ..:. : . . . :: :. . ::
NP_859 FVKPRQ---HMAKCQLS------GPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNN--
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 CRNYNKQASEQNWANYSAEQNRMGQAGST----ISNSHAQPFDFPDDNQNSKKLAAGHEL
.::.:: : .:: : :: . :. ..: . :. .. ::.:
NP_859 ------MASQQNTDNLVTEQVR-GQEQTPGEGFIQVRYGQKPEVPNG------VSPGHRL
290 300 310 320 330
360 370 380
pF1KB9 QPLAIVDQRPSSRASSRASSRPRPDDLEI
:.: :.:::.: : ::: .
NP_859 PHGYHSDKRRLSKASSKA----RSDDLSV
340 350
382 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:46:57 2016 done: Fri Nov 4 19:46:58 2016
Total Scan time: 9.020 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]