Result of FASTA (omim) for
pFN21AB9716
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9716, 393 aa
1>>>pF1KB9716 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7942+/-0.000349; mu= 1.4393+/- 0.022
mean_var=182.5098+/-37.504, 0's: 0 Z-trim(120.2): 68 B-trim: 0 in 0/55
Lambda= 0.094936
statistics sampled from 35058 (35127) to 35058 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.412), width: 16
Scan time: 8.420
The best scores are: opt bits E(85289)
XP_016871777 (OMIM: 120330,167409,191830,616002) P ( 424) 2663 376.7 5.6e-104
NP_000269 (OMIM: 120330,167409,191830,616002) pair ( 394) 2641 373.7 4.3e-103
NP_001291498 (OMIM: 120330,167409,191830,616002) p ( 425) 2641 373.7 4.6e-103
NP_003980 (OMIM: 120330,167409,191830,616002) pair ( 409) 2488 352.7 9e-97
XP_016871775 (OMIM: 120330,167409,191830,616002) P ( 440) 2488 352.7 9.6e-97
NP_003979 (OMIM: 120330,167409,191830,616002) pair ( 396) 2278 324.0 4e-88
XP_016871776 (OMIM: 120330,167409,191830,616002) P ( 427) 2278 324.0 4.2e-88
XP_005251538 (OMIM: 167414,615545) PREDICTED: pair ( 390) 1934 276.8 6e-74
NP_057953 (OMIM: 167414,615545) paired box protein ( 391) 1848 265.1 2.1e-70
XP_011510096 (OMIM: 167415,218700) PREDICTED: pair ( 387) 1657 238.9 1.6e-62
XP_011510095 (OMIM: 167415,218700) PREDICTED: pair ( 444) 1646 237.4 5e-62
NP_001267477 (OMIM: 167414,615545) paired box prot ( 362) 1552 224.5 3.2e-58
NP_003978 (OMIM: 120330,167409,191830,616002) pair ( 417) 1399 203.6 7.3e-52
XP_016871774 (OMIM: 120330,167409,191830,616002) P ( 448) 1399 203.6 7.7e-52
NP_003981 (OMIM: 120330,167409,191830,616002) pair ( 432) 1394 202.9 1.2e-51
XP_016871773 (OMIM: 120330,167409,191830,616002) P ( 463) 1394 202.9 1.3e-51
NP_001267476 (OMIM: 167414,615545) paired box prot ( 357) 1352 197.1 5.5e-50
NP_001267481 (OMIM: 167414,615545) paired box prot ( 328) 1338 195.2 1.9e-49
XP_011516199 (OMIM: 167414,615545) PREDICTED: pair ( 409) 1332 194.4 4.1e-49
NP_039246 (OMIM: 167415,218700) paired box protein ( 398) 1287 188.2 2.9e-47
XP_016860368 (OMIM: 167415,218700) PREDICTED: pair ( 402) 1283 187.7 4.3e-47
XP_011510094 (OMIM: 167415,218700) PREDICTED: pair ( 455) 1276 186.8 9.2e-47
XP_016860367 (OMIM: 167415,218700) PREDICTED: pair ( 459) 1272 186.2 1.4e-46
NP_003457 (OMIM: 167415,218700) paired box protein ( 450) 1267 185.5 2.1e-46
XP_011510093 (OMIM: 167415,218700) PREDICTED: pair ( 500) 1256 184.0 6.6e-46
XP_011510092 (OMIM: 167415,218700) PREDICTED: pair ( 507) 1256 184.0 6.7e-46
XP_011516198 (OMIM: 167414,615545) PREDICTED: pair ( 410) 1246 182.6 1.5e-45
NP_001267478 (OMIM: 167414,615545) paired box prot ( 324) 1228 180.1 6.6e-45
NP_001267485 (OMIM: 167414,615545) paired box prot ( 283) 1225 179.7 7.8e-45
NP_001267479 (OMIM: 167414,615545) paired box prot ( 295) 1214 178.2 2.3e-44
NP_039247 (OMIM: 167415,218700) paired box protein ( 321) 1186 174.3 3.5e-43
NP_054698 (OMIM: 167415,218700) paired box protein ( 287) 1166 171.6 2.1e-42
XP_016871770 (OMIM: 120330,167409,191830,616002) P ( 496) 1115 164.7 4.3e-40
XP_016871778 (OMIM: 120330,167409,191830,616002) P ( 374) 923 138.4 2.8e-32
XP_016871771 (OMIM: 120330,167409,191830,616002) P ( 483) 905 136.0 1.9e-31
XP_016871772 (OMIM: 120330,167409,191830,616002) P ( 483) 905 136.0 1.9e-31
NP_001267482 (OMIM: 167414,615545) paired box prot ( 319) 875 131.8 2.3e-30
NP_001267483 (OMIM: 167414,615545) paired box prot ( 348) 875 131.8 2.5e-30
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 780 118.8 2.3e-26
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 780 118.8 2.4e-26
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 780 118.8 2.4e-26
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 780 118.8 2.4e-26
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 780 118.8 2.4e-26
NP_006183 (OMIM: 167411,615560) paired box protein ( 534) 723 111.1 6.6e-24
NP_001267480 (OMIM: 167414,615545) paired box prot ( 220) 715 109.7 6.8e-24
NP_001244025 (OMIM: 167411,615560) paired box prot ( 457) 700 107.9 5.2e-23
NP_006185 (OMIM: 167416,604625) paired box protein ( 341) 669 103.6 7.7e-22
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 654 101.6 4.3e-21
NP_039230 (OMIM: 122880,148820,193500,268220,60659 ( 206) 642 99.7 6.6e-21
NP_000429 (OMIM: 122880,148820,193500,268220,60659 ( 215) 642 99.7 6.8e-21
>>XP_016871777 (OMIM: 120330,167409,191830,616002) PREDI (424 aa)
initn: 2663 init1: 2663 opt: 2663 Z-score: 1987.7 bits: 376.7 E(85289): 5.6e-104
Smith-Waterman score: 2663; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:32-424)
10 20 30
pF1KB9 MDMHCKADPFSAMHRHGGVNQLGGVFVNGR
::::::::::::::::::::::::::::::
XP_016 EERAGPAVLKLSLRGDTAAAAALLPLLCLPMDMHCKADPFSAMHRHGGVNQLGGVFVNGR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 PLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 TPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 DGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 VPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 ALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYP
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB9 TSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAY
370 380 390 400 410 420
pF1KB9 DRH
:::
XP_016 DRH
>>NP_000269 (OMIM: 120330,167409,191830,616002) paired b (394 aa)
initn: 2642 init1: 2547 opt: 2641 Z-score: 1971.9 bits: 373.7 E(85289): 4.3e-103
Smith-Waterman score: 2641; 99.5% identity (99.5% similar) in 394 aa overlap (1-393:1-394)
10 20 30 40 50
pF1KB9 MDMHCKADPFSAMHR-HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
:::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA
310 320 330 340 350 360
360 370 380 390
pF1KB9 WRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH
::::::::::::::::::::::::::::::::::
NP_000 WRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH
370 380 390
>>NP_001291498 (OMIM: 120330,167409,191830,616002) paire (425 aa)
initn: 2642 init1: 2547 opt: 2641 Z-score: 1971.4 bits: 373.7 E(85289): 4.6e-103
Smith-Waterman score: 2641; 99.5% identity (99.5% similar) in 394 aa overlap (1-393:32-425)
10 20
pF1KB9 MDMHCKADPFSAMHR-HGGVNQLGGVFVNG
:::::::::::::: ::::::::::::::
NP_001 EERAGPAVLKLSLRGDTAAAAALLPLLCLPMDMHCKADPFSAMHPGHGGVNQLGGVFVNG
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB9 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB9 ATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPT
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 PDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 SVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSL
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB9 PALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSY
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB9 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAA
370 380 390 400 410 420
390
pF1KB9 YDRH
::::
NP_001 YDRH
>>NP_003980 (OMIM: 120330,167409,191830,616002) paired b (409 aa)
initn: 2482 init1: 2387 opt: 2488 Z-score: 1858.4 bits: 352.7 E(85289): 9e-97
Smith-Waterman score: 2488; 94.4% identity (95.2% similar) in 394 aa overlap (1-393:1-394)
10 20 30 40 50
pF1KB9 MDMHCKADPFSAMHR-HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
:::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_003 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEA
310 320 330 340 350 360
360 370 380 390
pF1KB9 WRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH
::::::::: : : : .:.. :
NP_003 WRFSNPALLMPPPGAPPLPLLPLPMTATSYRGDHIKLQADSFGLHIVPV
370 380 390 400
>>XP_016871775 (OMIM: 120330,167409,191830,616002) PREDI (440 aa)
initn: 2482 init1: 2387 opt: 2488 Z-score: 1857.9 bits: 352.7 E(85289): 9.6e-97
Smith-Waterman score: 2488; 94.4% identity (95.2% similar) in 394 aa overlap (1-393:32-425)
10 20
pF1KB9 MDMHCKADPFSAMHR-HGGVNQLGGVFVNG
:::::::::::::: ::::::::::::::
XP_016 EERAGPAVLKLSLRGDTAAAAALLPLLCLPMDMHCKADPFSAMHPGHGGVNQLGGVFVNG
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB9 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB9 ATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPT
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 PDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 SVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSL
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB9 PALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSY
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB9 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAA
::::::::::::::::::::::::::::::::::::::: : : : .:..
XP_016 PTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGAPPLPLLPLPMTATSY
370 380 390 400 410 420
390
pF1KB9 YDRH
:
XP_016 RGDHIKLQADSFGLHIVPV
430 440
>>NP_003979 (OMIM: 120330,167409,191830,616002) paired b (396 aa)
initn: 2267 init1: 2172 opt: 2278 Z-score: 1703.1 bits: 324.0 E(85289): 4e-88
Smith-Waterman score: 2278; 91.3% identity (94.0% similar) in 381 aa overlap (1-378:1-380)
10 20 30 40 50
pF1KB9 MDMHCKADPFSAMHR-HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
:::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_003 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEF--SGNPYSHPQYTAYN
:::::::::::::::::::::::::::::::::::::::: . :.. .:.:
NP_003 TYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPEAAVGPSSSLMSKPGRK-LA
310 320 330 340 350
360 370 380 390
pF1KB9 EAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH
:. .:. ::: .:.:
NP_003 EVPPCVQPTGASSPATRTATPSTRPTTRLGDSATPPY
360 370 380 390
>>XP_016871776 (OMIM: 120330,167409,191830,616002) PREDI (427 aa)
initn: 2267 init1: 2172 opt: 2278 Z-score: 1702.6 bits: 324.0 E(85289): 4.2e-88
Smith-Waterman score: 2278; 91.3% identity (94.0% similar) in 381 aa overlap (1-378:32-411)
10 20
pF1KB9 MDMHCKADPFSAMHR-HGGVNQLGGVFVNG
:::::::::::::: ::::::::::::::
XP_016 EERAGPAVLKLSLRGDTAAAAALLPLLCLPMDMHCKADPFSAMHPGHGGVNQLGGVFVNG
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB9 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKV
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB9 ATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPT
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 PDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 SVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSL
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB9 PALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSY
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB9 PTSTLAGMVPGSEF--SGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAA
:::::::::: . :.. .:.: :. .:. ::: .:.:
XP_016 PTSTLAGMVPEAAVGPSSSLMSKPGRK-LAEVPPCVQPTGASSPATRTATPSTRPTTRLG
370 380 390 400 410 420
390
pF1KB9 AAYDRH
XP_016 DSATPPY
>>XP_005251538 (OMIM: 167414,615545) PREDICTED: paired b (390 aa)
initn: 1642 init1: 962 opt: 1934 Z-score: 1448.6 bits: 276.8 E(85289): 6e-74
Smith-Waterman score: 1934; 72.6% identity (86.9% similar) in 398 aa overlap (1-393:1-390)
10 20 30 40 50 60
pF1KB9 MDMHCKADPFSAMHRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVS
:..::: :::..::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEIHCKHDPFASMHRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 HGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAE
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
XP_005 HGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAE
70 80 90 100 110 120
130 140 150 160 170
pF1KB9 GICDNDTVPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASND
.::::::::::::::::::::::: . :.: : .:.:: . . :::.:.:
XP_005 RVCDNDTVPSVSSINRIIRTKVQQPPNQPVP--------ASSHSIVSTGSVTQVSSVSTD
130 140 150 160 170
180 190 200 210 220 230
pF1KB9 PVGS-YSINGILGI--PRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQ
.:: :::.::::: : .. .:::::: ..:. :::: : : : :::..:.: :::::
XP_005 SAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LEALDRVFERPSYPDVFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSASTNPELGSNV
::.::::::: : :.: ..: :: :: .::: . .:. :::..:..:.. : ..::.:
XP_005 LEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 SGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTA
: :.::.:::::.::::::::::::::.::::: . ::.::::::::::.:::::::..
XP_005 PGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSS
300 310 320 330 340 350
360 370 380 390
pF1KB9 YNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH
::..::: ::.::.:::::::: ::.:: :::.:::::
XP_005 YNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH
360 370 380 390
>>NP_057953 (OMIM: 167414,615545) paired box protein Pax (391 aa)
initn: 1552 init1: 872 opt: 1848 Z-score: 1384.9 bits: 265.1 E(85289): 2.1e-70
Smith-Waterman score: 1848; 71.0% identity (84.8% similar) in 400 aa overlap (1-393:1-391)
10 20 30 40 50
pF1KB9 MDMHCKADPFSAMHR--HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR
::.. : : : :::::::::::::::::::::::::::::::::::::::::::
NP_057 MDLE-KNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLL
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
NP_057 VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEGICDNDTVPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSAS
:: .::::::::::::::::::::::: . :.: : .:.:: . . :::.:
NP_057 AERVCDNDTVPSVSSINRIIRTKVQQPPNQPVP--------ASSHSIVSTGSVTQVSSVS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 NDPVGS-YSINGILGI--PRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQ
.: .:: :::.::::: : .. .:::::: ..:. :::: : : : :::..:.: :::
NP_057 TDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 QQLEALDRVFERPSYPDVFQASEHIKSEQGNEYS-LPALTPGLDEVKSSLSASTNPELGS
::::.::::::: : :.: ..: :: :: .::: . .:. :::..:..:.. : ..::
NP_057 QQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 NVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQY
.: : :.::.:::::.::::::::::::::.::::: . ::.::::::::::.:::::::
NP_057 SVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQY
300 310 320 330 340 350
360 370 380 390
pF1KB9 TAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH
..::..::: ::.::.:::::::: ::.:: :::.:::::
NP_057 SSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH
360 370 380 390
>>XP_011510096 (OMIM: 167415,218700) PREDICTED: paired b (387 aa)
initn: 1466 init1: 1191 opt: 1657 Z-score: 1243.6 bits: 238.9 E(85289): 1.6e-62
Smith-Waterman score: 1657; 65.3% identity (84.9% similar) in 378 aa overlap (16-391:10-385)
10 20 30 40 50 60
pF1KB9 MDMHCKADPFSAMHRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVS
:::.:::::.::::::::.:::::::.::::::::::::::::::
XP_011 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVS
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 HGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAE
:::::::::::::::::.:::::::::::::::::.::..::::::::::::::::::::
XP_011 HGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAE
60 70 80 90 100 110
130 140 150 160 170
pF1KB9 GICDNDTVPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASND
:.::::::::::::::::::::::::. : . ..: .::::..::.: : : ..:
XP_011 GVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 PVGS-YSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLE
.:: :::::.::: . ...::: :.. ... . ::::. .. :::::.:.:.:..::
XP_011 SLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 ALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGT
:. ::: ::... . : :.::: : :: :. ::. :..:. :..: :: :.:
XP_011 PLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLSTH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 QTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNE
::::::.::.:.. ::::::::.: .::::: .:..:::: :::.::: :.: :..:.:
XP_011 QTYPVVAGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSE
300 310 320 330 340 350
360 370 380 390
pF1KB9 AWRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH
:::: : .:::::::::.. : ::: ..:.:.:
XP_011 AWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDHL
360 370 380
393 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:29:38 2016 done: Fri Nov 4 18:29:40 2016
Total Scan time: 8.420 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]