Result of FASTA (omim) for
pFN21AB9652
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9652, 317 aa
1>>>pF1KB9652 317 - 317 aa - 317 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0046+/-0.00029; mu= 9.6138+/- 0.018
mean_var=144.8902+/-30.744, 0's: 0 Z-trim(121.4): 178 B-trim: 331 in 1/59
Lambda= 0.106550
statistics sampled from 37683 (37920) to 37683 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.445), width: 16
Scan time: 8.670
The best scores are: opt bits E(85289)
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 2167 344.1 2.3e-94
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446) 923 152.9 1.1e-36
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391) 780 130.9 4.1e-30
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276) 620 106.2 8e-23
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240) 601 103.2 5.5e-22
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233) 499 87.5 2.8e-17
NP_071899 (OMIM: 610928,613674) transcription fact ( 414) 466 82.7 1.5e-15
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446) 433 77.6 5.2e-14
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204) 424 76.0 7.5e-14
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384) 422 75.9 1.5e-13
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315) 415 74.7 2.7e-13
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 412 74.4 5e-13
NP_003099 (OMIM: 600898,615866) transcription fact ( 441) 410 74.1 5.9e-13
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 407 73.7 9.1e-13
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474) 402 72.9 1.5e-12
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388) 386 70.3 7e-12
NP_821078 (OMIM: 604975,616803) transcription fact ( 377) 338 63.0 1.1e-09
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415) 338 63.0 1.2e-09
NP_001248343 (OMIM: 604975,616803) transcription f ( 642) 338 63.2 1.7e-09
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715) 338 63.2 1.8e-09
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715) 338 63.2 1.8e-09
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715) 338 63.2 1.8e-09
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715) 338 63.2 1.8e-09
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716) 338 63.2 1.8e-09
NP_001317714 (OMIM: 604975,616803) transcription f ( 728) 338 63.2 1.9e-09
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729) 338 63.2 1.9e-09
NP_694534 (OMIM: 604975,616803) transcription fact ( 750) 338 63.2 1.9e-09
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750) 338 63.2 1.9e-09
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751) 338 63.2 1.9e-09
NP_001248344 (OMIM: 604975,616803) transcription f ( 753) 338 63.2 1.9e-09
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754) 338 63.2 1.9e-09
NP_008871 (OMIM: 604975,616803) transcription fact ( 763) 338 63.2 1.9e-09
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764) 338 63.2 1.9e-09
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792) 338 63.2 2e-09
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793) 338 63.2 2e-09
NP_001139283 (OMIM: 607257) transcription factor S ( 801) 329 61.9 5.2e-09
NP_059978 (OMIM: 607257) transcription factor SOX- ( 804) 329 61.9 5.2e-09
NP_201583 (OMIM: 607257) transcription factor SOX- ( 808) 329 61.9 5.2e-09
NP_001139291 (OMIM: 607257) transcription factor S ( 841) 329 61.9 5.4e-09
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621) 316 59.8 1.7e-08
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622) 316 59.8 1.7e-08
XP_005258732 (OMIM: 612082) PREDICTED: protein cap (1605) 311 59.3 5.9e-08
>>NP_003097 (OMIM: 184429,189960,206900) transcription f (317 aa)
initn: 2167 init1: 2167 opt: 2167 Z-score: 1815.1 bits: 344.1 E(85289): 2.3e-94
Smith-Waterman score: 2167; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KB9 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 KKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 PQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQS
250 260 270 280 290 300
310
pF1KB9 GPVPGTAINGTLPLSHM
:::::::::::::::::
NP_003 GPVPGTAINGTLPLSHM
310
>>NP_005625 (OMIM: 300123,312000,313430) transcription f (446 aa)
initn: 1183 init1: 656 opt: 923 Z-score: 779.6 bits: 152.9 E(85289): 1.1e-36
Smith-Waterman score: 1153; 52.8% identity (74.0% similar) in 377 aa overlap (1-317:76-446)
10 20
pF1KB9 MYNMMETELKPP-G-PQQTSG-------GG
::...::::: : : : :..: ::
NP_005 ESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGG
50 60 70 80 90 100
30 40 50 60
pF1KB9 GGNSTAAAAGGNQKNS--------------PDRVKRPMNAFMVWSRGQRRKMAQENPKMH
.:.:.: :::: .... :::::::::::::::::::::: ::::::
NP_005 AGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMH
110 120 130 140 150 160
70 80 90 100 110 120
pF1KB9 NSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTL
::::::::::.::::...::::::::::::::.::::.::::::::::::::.:::::.:
NP_005 NSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSL
170 180 190 200 210 220
130 140 150 160 170 180
pF1KB9 PGGLLAPGGNSMASGVGVGAGLGA---GVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHP
:.::: ::. . :......:. .. ::.::.:.:.:.:::.::.::..:.:::: : :
NP_005 PSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPP
230 240 250 260 270 280
190 200 210 220
pF1KB9 GLNAHGAAQ-MQPMHRYDVSALQYNSMT--SSQTYMN---------G----SPTYSMS--
.... . ::::::...:::. : ..:.::: : .:. . .
NP_005 SMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAA
290 300 310 320 330 340
230 240 250 260 270
pF1KB9 --YSQQ---------GTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMIS
:.:: .. .:.:: :::::::: :: ::.. .:::. : ::::::::
NP_005 AAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAI--ASHSQRACL-GDLRDMIS
350 360 370 380 390 400
280 290 300 310
pF1KB9 MYLP-GAEVPEPAAP---SRLH-MSQHYQSGPVPGTAINGTLPLSHM
:::: :... . :.: .::: . ::::.. :::.:::.::.:.
NP_005 MYLPPGGDAADAASPLPGGRLHGVHQHYQGA---GTAVNGTVPLTHI
410 420 430 440
>>NP_005977 (OMIM: 602148) transcription factor SOX-1 [H (391 aa)
initn: 1037 init1: 728 opt: 780 Z-score: 661.6 bits: 130.9 E(85289): 4.1e-30
Smith-Waterman score: 1095; 54.0% identity (69.7% similar) in 363 aa overlap (1-288:1-358)
10 20 30 40 50
pF1KB9 MYNMM-ETELKPPGPQQT---------SGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMV
::.:: ::.:. :: :. .:::::.. ....::. : . ::::::::::::
NP_005 MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 WSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKY
::::::::::::::::::::::::::::::..::.:::::::::::::::::::::::::
NP_005 WSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKY
70 80 90 100 110 120
120 130 140 150
pF1KB9 RPRRKTKTLMKKDKYTLPGGLLAPG----GNSMASGVGVGAGLGAGVNQRMDS-------
:::::::::.:::::.: ::::: : : ..: :::::.: .:.:.::..:
NP_005 RPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVG-AAAVGQRLESPGGAAGG
130 140 150 160 170
160 170 180 190
pF1KB9 -YAHMNGWSNGSY-----------SMMQD-QLGYPQHPGL-----NAHGAAQM-------
:::.:::.::.: .:::. ::.: :::: .:: :
NP_005 GYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAH
180 190 200 210 220 230
200 210 220 230
pF1KB9 ----QPMHRYDVSALQYNSMTSSQTYMNGSPT------YSMSYSQQGTPGMA--------
:::::::..::::. ...:: ::..::. :. . . .. : :
NP_005 PHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAA
240 250 260 270 280 290
240 250 260 270 280
pF1KB9 -----------LGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPE
::..::.:::: :.::: . .:::::: ::::.:::::::..: .
NP_005 AAAAAAASSGALGALGSLVKSEPSGSPP---APAHSRAPCP-GDLREMISMYLPAGEGGD
300 310 320 330 340 350
290 300 310
pF1KB9 PAAPSRLHMSQHYQSGPVPGTAINGTLPLSHM
:::
NP_005 PAAAAAAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI
360 370 380 390
>>NP_009015 (OMIM: 604974) transcription factor SOX-21 [ (276 aa)
initn: 624 init1: 569 opt: 620 Z-score: 530.7 bits: 106.2 E(85289): 8e-23
Smith-Waterman score: 620; 43.0% identity (62.9% similar) in 272 aa overlap (39-304:6-269)
10 20 30 40 50 60
pF1KB9 LKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHN
:.:::::::::::::.::::::::::::::
NP_009 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHN
10 20 30
70 80 90 100 110 120
pF1KB9 SEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP
::::::::::::::.:.::::::::::::::.::::::::::::::: :::.::::...:
NP_009 SEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFP
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 -----GGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQH
::. .. .:.:. :: :.:. .: . .. . .. .::
NP_009 VPYGLGGVADAEHPALKAGAGLHAGAGGGLVP--ESLLANPEKAAAAAAAAAARVFFPQS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 PGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSM-GS
. : .:: :.. : ..:. .. .: : :. :. : : . :.. :.
NP_009 AAAAAAAAAAAAAGSPYSLLDLG-SKMAEISSSSSGLP-YA---SSLGYPTAGAGAFHGA
160 170 180 190 200
250 260 270 280 290 300
pF1KB9 VVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGP
.. . :... . :: .: . : . :. . : : : . : :
NP_009 AAAAAAAAAAAGGHTHSHP-SPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDP
210 220 230 240 250 260
310
pF1KB9 VPGTAINGTLPLSHM
:
NP_009 YPAAYAAAL
270
>>NP_004180 (OMIM: 604747) transcription factor SOX-14 [ (240 aa)
initn: 626 init1: 574 opt: 601 Z-score: 515.7 bits: 103.2 E(85289): 5.5e-22
Smith-Waterman score: 601; 48.6% identity (69.5% similar) in 220 aa overlap (39-254:6-216)
10 20 30 40 50 60
pF1KB9 LKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHN
:..:::::::::::::::::::::::::::
NP_004 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHN
10 20 30
70 80 90 100 110 120
pF1KB9 SEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLP
::::::::::::::::.::::.::::::::: ::::::::::::::: :.:.:::.:..:
NP_004 SEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFP
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 GGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNA
:. :.:. :::. : .. . : . ... ::... : . . .:
NP_004 LPYLGDTDPLKAAGLPVGASDGL-LSAPEKARAFLPP-ASAPYSLLD-----PAQFSSSA
100 110 120 130 140
190 200 210 220 230 240
pF1KB9 HGAAQMQPMHRYDVSALQYNSMTSSQTYMNGS---PT-YSMSYSQQGTPGMALGSMGSVV
: : ..:: : : . :. :: :. .. .. . .::... . ..
NP_004 IQKMGEVP-HTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVV-PCNCTA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB9 KSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGPVP
: .. .:::
NP_004 WSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM
210 220 230 240
>>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens] (233 aa)
initn: 477 init1: 458 opt: 499 Z-score: 431.2 bits: 87.5 E(85289): 2.8e-17
Smith-Waterman score: 499; 43.9% identity (64.5% similar) in 214 aa overlap (13-221:28-227)
10 20 30 40
pF1KB9 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSP-DRVKRP
:::. :.: . :: : . : ..::::
NP_008 MALPGSSQDQAWSLEPPAATAAASSSSGPQEREGAG----SPAAPG----TLPLEKVKRP
10 20 30 40 50
50 60 70 80 90 100
pF1KB9 MNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKE
:::::::: .:::.:::.:::::::::::::::.::::.: :::::..::::::: :...
NP_008 MNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB9 HPDYKYRPRRKTKTLMKKDKYTLPG-GLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHM
.::::::::::.:. . : : :: :: . : .. . : . : ::.
NP_008 YPDYKYRPRRKAKSSGAGPSRCGQGRGNLASGGPLWGPGYATTQP-SRGFGYRPPSYS--
120 130 140 150 160
170 180 190 200 210 220
pF1KB9 NGWSNGSYSMMQDQLGYPQH---PGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGS
... :::. . .: :. : . . ... : . . : .: : . . :.
NP_008 TAYLPGSYGSSHCKLEAPSPCSLPQSDPRLQGELLPTYTH---YLPPGSPTPYNPPLAGA
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB9 PTYSMSYSQQGTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPG
:
NP_008 PMPLTHL
230
>>NP_071899 (OMIM: 610928,613674) transcription factor S (414 aa)
initn: 467 init1: 398 opt: 466 Z-score: 400.4 bits: 82.7 E(85289): 1.5e-15
Smith-Waterman score: 468; 31.7% identity (56.7% similar) in 312 aa overlap (9-305:36-331)
10 20 30
pF1KB9 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSP
:.: : ....: . .:: : :..... ..
NP_071 AGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR
.:..:::::::::.. .:...::.:: .::.:.:: :: :: :. .:::::..::.:::
NP_071 SRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 ALHMKEHPDYKYRPRRKTKTLMKKDKYTLPG---GLLAPGGNSMASGVGVGAGLGAGVNQ
. ::..::.:::::::. . .:. : . : :: : . ... : : : :..
NP_071 VQHMQDHPNYKYRPRRRKQ--VKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLGLQF
130 140 150 160 170 180
160 170 180 190 200
pF1KB9 RMDSYA--------HMNGWSNGSYSMMQDQL-GYPQHPGLNAHGAAQMQPMHRYDVSALQ
... ::.: :. : ::: : . . .:. : .
NP_071 PEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPL-P------TPDTSPLDGVDPDPAF
190 200 210 220 230
210 220 230 240 250 260
pF1KB9 YNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSMGSVVKSE-ASSSPPVVTSSSHSRAPC
. . .. :. .:.. . : : : : . : :. : : . ::
NP_071 FAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLL------APP
240 250 260 270 280 290
270 280 290 300 310
pF1KB9 QAGDLRDMISMYLPGAEVPE--PAAPSRLHMSQHYQSGPVPGTAINGTLPLSHM
.: . . .: ::: . :.. :. :: . : ::
NP_071 SALHVY-YGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTDPS
300 310 320 330 340
NP_071 QPAELLGEVDRTEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYC
350 360 370 380 390 400
>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H (446 aa)
initn: 387 init1: 387 opt: 433 Z-score: 372.6 bits: 77.6 E(85289): 5.2e-14
Smith-Waterman score: 441; 31.5% identity (56.0% similar) in 327 aa overlap (14-313:85-396)
10 20 30 40
pF1KB9 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKR
:. . :::: : : .: .:::
NP_055 DPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGG---------GALKAKP-HVKR
60 70 80 90 100
50 60 70 80 90 100
pF1KB9 PMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMK
::::::::... :::.:.. :..::.:.:: :: :.::::.:::::..::.:::. : :
NP_055 PMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKK
110 120 130 140 150 160
110 120 130 140 150 160
pF1KB9 EHPDYKYRPRRKTKTLMKKDKYTLPGGLLAP--GGNSMASGVGVGAGLGAGVNQRMDSYA
.::::::.:::. :. . . :. :.: ::... . . :::: : ... : .
NP_055 DHPDYKYQPRRR-KSAKAGHSDSDSGAELGPHPGGGAVYK---AEAGLGDG-HHHGDHTG
170 180 190 200 210
170 180 190 200 210
pF1KB9 HMNGWSNGSYSMMQDQLGYPQHPGLNAHG------AAQMQPMHRYDVSALQYNSMTSSQT
. .: . . . .: :. .: . : . :.: :. . : . ..
NP_055 QTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDA
220 230 240 250 260 270
220 230 240 250
pF1KB9 --------YMN-GSPT-------YSMSYSQQG-TPGMALGSMGSVVKSEASSSPPVVTSS
:. :.:. :. .: . : .: : : :. : . ..:: .
NP_055 FDVHEFDQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIK
280 290 300 310 320 330
260 270 280 290 300 310
pF1KB9 SHSRAPCQAGDLRDMISMY--LPGAEVPEPAAPSRLHMSQHYQSGPVPGTAINGTLPLSH
... .: . :: : : ::::. ... . : . ... :. :
NP_055 TEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYA
340 350 360 370 380 390
pF1KB9 M
NP_055 PGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
400 410 420 430 440
>>NP_003131 (OMIM: 400044,400045,480000) sex-determining (204 aa)
initn: 434 init1: 416 opt: 424 Z-score: 369.6 bits: 76.0 E(85289): 7.5e-14
Smith-Waterman score: 439; 45.6% identity (69.6% similar) in 171 aa overlap (31-200:49-198)
10 20 30 40 50
pF1KB9 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQK-NSPDRVKRPMNAFMVWSRGQRRKM
: :.: : ::::::::::.:::: :::::
NP_003 PAVQENIPALRRSSSFLCTESCNSKYQCETGENSKGNVQDRVKRPMNAFIVWSRDQRRKM
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB9 AQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTL
: :::.:.::::::.:: .::.:.:.:: ::..::..:.:.: ...:.::::::::.: .
NP_003 ALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKAK-M
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB9 MKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLG
. :. :: : .. . : : ..:. . . .....: :. :::
NP_003 LPKNCSLLP----ADPASVLCSEV------------QLDNRLYRDDCTKATHSRMEHQLG
140 150 160 170 180
180 190 200 210 220 230
pF1KB9 YPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGS
. : .:: :.. : ::
NP_003 H--LPPINA--ASSPQQRDRYSHWTKL
190 200
>>NP_060889 (OMIM: 137940,601618,607823) transcription f (384 aa)
initn: 439 init1: 383 opt: 422 Z-score: 364.3 bits: 75.9 E(85289): 1.5e-13
Smith-Waterman score: 422; 46.5% identity (74.4% similar) in 129 aa overlap (11-135:51-176)
10 20 30
pF1KB9 MYNMMETELKPPGPQQTSGGGG--GNSTAAAAGGNQKNSP
::.::.. . : . :: .....
NP_060 AWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPRSPEPGRYGLSPAGRGERQAA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 D--RVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKR
: :..:::::::::.. .:...::.:: .::. .:: :: :: :. .:::::..::.:
NP_060 DESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAER
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB9 LRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQR
::. :...::.:::::::: .. .: . :: :: ::
NP_060 LRVQHLRDHPNYKYRPRRKKQA--RKARRLEPG-LLLPGLAPPQPPPEPFPAASGSARAF
150 160 170 180 190
160 170 180 190 200 210
pF1KB9 MDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTY
NP_060 RELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRD
200 210 220 230 240 250
317 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:58:41 2016 done: Fri Nov 4 17:58:42 2016
Total Scan time: 8.670 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]