Result of FASTA (ccds) for
pFN21AB8919
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8919, 264 aa
1>>>pF1KB8919 264 - 264 aa - 264 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3941+/-0.00083; mu= 6.1050+/- 0.051
mean_var=293.6398+/-59.611, 0's: 0 Z-trim(117.7): 131 B-trim: 1047 in 1/55
Lambda= 0.074846
statistics sampled from 18359 (18511) to 18359 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.843), E-opt: 0.2 (0.569), width: 16
Scan time: 2.830
The best scores are: opt bits E(32554)
CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 ( 264) 1873 214.3 7.2e-56
CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 ( 251) 925 111.9 4.5e-25
CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 ( 255) 909 110.2 1.5e-24
CCDS5405.1 HOXA4 gene_id:3201|Hs108|chr7 ( 320) 705 88.3 7.5e-18
CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 ( 270) 529 69.2 3.5e-12
CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 ( 269) 497 65.7 3.9e-11
>>CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 (264 aa)
initn: 1873 init1: 1873 opt: 1873 Z-score: 1116.6 bits: 214.3 E(32554): 7.2e-56
Smith-Waterman score: 1873; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264)
10 20 30 40 50 60
pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 SYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 APDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 APDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATP
190 200 210 220 230 240
250 260
pF1KB8 GTSEDHSQSATPPEQQRAEDITRL
::::::::::::::::::::::::
CCDS88 GTSEDHSQSATPPEQQRAEDITRL
250 260
>>CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 (251 aa)
initn: 1092 init1: 704 opt: 925 Z-score: 563.6 bits: 111.9 E(32554): 4.5e-25
Smith-Waterman score: 953; 59.9% identity (71.8% similar) in 252 aa overlap (1-231:1-237)
10 20 30 40
pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIP-EHSPEYY--GRTRESGFQHHH--------
: :::.:..:::.::::::::::::..:.: .::: :: :. :::.:: .
CCDS11 MAMSSFLINSNYVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQRRESSFQPEAGFGRRAAC
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 --------QELYPPPPPRPSYPERQYSCTSLQGPGNS-RGHGPAQAGHHHPEKSQSLCEP
.. ::::: : : :: : :. .: :: :: .: ::
CCDS11 TVQRYAACRDPGPPPPPPPPPPPPP-------PPGLSPRAPAPPPAGALLPEPGQR-CE-
70 80 90 100 110
110 120 130 140 150
pF1KB8 APLSGASASPSPAPPACSQ-PAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRS
..: :: :: :.: : :: .: :.:.:::::.:.::::::::: :::::::
CCDS11 ------AVSSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRS
120 130 140 150 160
160 170 180 190 200 210
pF1KB8 RTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPN
:::::::::::::::::::::::::::.::::.:::::::::::::::::::::::.:::
CCDS11 RTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPN
170 180 190 200 210 220
220 230 240 250 260
pF1KB8 TKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL
::.::. ::.:
CCDS11 TKIRSGGAAGSAGGPPGRPNGGPRAL
230 240 250
>>CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 (255 aa)
initn: 828 init1: 597 opt: 909 Z-score: 554.2 bits: 110.2 E(32554): 1.5e-24
Smith-Waterman score: 909; 55.1% identity (73.5% similar) in 272 aa overlap (1-264:1-255)
10 20 30 40 50
pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPP-PPR
:.::::...:.:.:::::::::: :..:. :.. .::: .: : .. :: ::
CCDS22 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYG----GGAQG--ADFQPPGLYPR
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 PSYPERQYSCTSLQGPGNS---RGHG--PAQAGHHHPEKSQSLCEPAPLSGASASPSPAP
:.. :. .. : :::.. :::: :. : :. .. : ::: . : : :.
CCDS22 PDFGEQPFG-GSGPGPGSALPARGHGQEPGGPGGHYAAPGEP-C-PAPPAPPPA-PLPGA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 PACSQPAPDHP-SSAASKQP-IVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELE
: :: : .: :..: ::: .:::::::.::..:::::.::::::::::::::::::::
CCDS22 RAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 KEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAP
::::.::::::::::::::.:::::::::::::::::::::::.::::: ::.
CCDS22 KEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSS-------
180 190 200 210 220
240 250 260
pF1KB8 STLSAATPGTSEDHSQSATPPEQQRAEDITRL
:. :... ..: :: : ... :.: :
CCDS22 SSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL
230 240 250
>>CCDS5405.1 HOXA4 gene_id:3201|Hs108|chr7 (320 aa)
initn: 820 init1: 659 opt: 705 Z-score: 434.0 bits: 88.3 E(32554): 7.5e-18
Smith-Waterman score: 705; 48.6% identity (62.5% similar) in 253 aa overlap (10-252:71-306)
10 20 30
pF1KB8 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGR
..: :. : . : :.
CCDS54 GYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTAREPAYPAAALYPAHGAA--DT
50 60 70 80 90
40 50 60 70 80 90
pF1KB8 TRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGP--GNSRGH------GPAQAGHHHP
. :.. . : ::.: : : .:: : .: : . :
CCDS54 AYPYGYRGGAS---PGRPPQPEQPPAQA-----KGPAHGLHASHVLQPQLPPPLQPRAVP
100 110 120 130 140 150
100 110 120 130 140
pF1KB8 EKSQSLCEPAPLS-GASASPSPAPPACSQPAPDH-PSSAASKQPIVYPWMKKIHVSTVNP
. :: :: . :. :. : ::: :. : . .:.:.:::::::::::.:::
CCDS54 PAAPRRCEAAPATPGVPAGGS--APACPLLLADKSPLGLKGKEPVVYPWMKKIHVSAVNP
160 170 180 190 200
150 160 170 180 190 200
pF1KB8 NYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRM
.::::::::::::::::::::::::::.::::::::::::::.:::::::.:::::::::
CCDS54 SYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRM
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB8 KWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL
::::::.:::::.::. :.: ::. :: .. .: :
CCDS54 KWKKDHKLPNTKMRSSNSASA-----SAGPPGKAQTQSPHLHPHPHPSTSTPVPSSI
270 280 290 300 310 320
>>CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 (270 aa)
initn: 586 init1: 382 opt: 529 Z-score: 332.1 bits: 69.2 E(32554): 3.5e-12
Smith-Waterman score: 529; 49.2% identity (64.9% similar) in 185 aa overlap (54-231:96-267)
30 40 50 60 70 80
pF1KB8 SQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQ-GPGNSRGHG
: : : : :... .::.. ::
CCDS54 SGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLP--------CSAVAPSPGSDSHHG
70 80 90 100 110
90 100 110 120 130
pF1KB8 -----PAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP-APDHPSSAASKQPIVY
..: : . .. ::.. :: . : : ..:: : :: .:
CCDS54 GKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIY
120 130 140 150 160 170
140 150 160 170 180 190
pF1KB8 PWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLS
:::.:.:.: . : .: : ::.:::::: :.::::::::.::::::::::::::.::::
CCDS54 PWMRKLHIS--HDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS
180 190 200 210 220 230
200 210 220 230 240 250
pF1KB8 ERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQ
::::::::::::::::::..: : : ::.:
CCDS54 ERQIKIWFQNRRMKWKKDNKL---KSMSMAAAGGAFRP
240 250 260 270
260
pF1KB8 RAEDITRL
>>CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 (269 aa)
initn: 452 init1: 384 opt: 497 Z-score: 313.5 bits: 65.7 E(32554): 3.9e-11
Smith-Waterman score: 520; 46.2% identity (67.2% similar) in 195 aa overlap (53-228:76-266)
30 40 50 60 70
pF1KB8 YSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGP-------
.: : .: . . :: ::..:
CCDS11 GYNYNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAASSC-SLSSPESLPCTN
50 60 70 80 90 100
80 90 100 110 120
pF1KB8 GNSRGHGP-AQAGHHHPEKSQSLCEPAPLSGASASPSPAPPAC---------SQPAPDHP
:.:.: : :.. . ...: . . .. :::: : : .:: :
CCDS11 GDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMAT
110 120 130 140 150 160
130 140 150 160 170 180
pF1KB8 SSAA--SKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTR
:.:: .. : ..:::.:.:.: ...: . ::.:::::: :.::::::::.::::::
CCDS11 STAAPEGQTPQIFPWMRKLHIS---HDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTR
170 180 190 200 210 220
190 200 210 220 230 240
pF1KB8 RRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTS
::::::::.::::::::::::::::::::::..: . .. .: :
CCDS11 RRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP
230 240 250 260
250 260
pF1KB8 EDHSQSATPPEQQRAEDITRL
264 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:29:59 2016 done: Fri Nov 4 16:30:00 2016
Total Scan time: 2.830 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]