Result of FASTA (ccds) for
pFN21AB8917
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8917, 260 aa
1>>>pF1KB8917 260 - 260 aa - 260 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9206+/-0.000834; mu= 9.9561+/- 0.051
mean_var=178.1111+/-36.621, 0's: 0 Z-trim(113.7): 144 B-trim: 79 in 1/51
Lambda= 0.096101
statistics sampled from 14100 (14285) to 14100 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.439), width: 16
Scan time: 2.500
The best scores are: opt bits E(32554)
CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12 ( 260) 1815 263.0 1.5e-70
CCDS11534.1 HOXB9 gene_id:3219|Hs108|chr17 ( 250) 714 110.3 1.3e-24
CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7 ( 272) 693 107.5 1e-23
CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 ( 352) 531 85.1 7.1e-17
CCDS5410.2 HOXA10 gene_id:3206|Hs108|chr7 ( 410) 464 75.9 4.9e-14
CCDS8868.1 HOXC10 gene_id:3226|Hs108|chr12 ( 342) 449 73.7 1.8e-13
CCDS2266.1 HOXD10 gene_id:3236|Hs108|chr2 ( 340) 431 71.2 1e-12
>>CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12 (260 aa)
initn: 1815 init1: 1815 opt: 1815 Z-score: 1380.1 bits: 263.0 E(32554): 1.5e-70
Smith-Waterman score: 1815; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260)
10 20 30 40 50 60
pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 VFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 NPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWF
190 200 210 220 230 240
250 260
pF1KB8 QNRRMKMKKMNKEKTDKEQS
::::::::::::::::::::
CCDS88 QNRRMKMKKMNKEKTDKEQS
250 260
>>CCDS11534.1 HOXB9 gene_id:3219|Hs108|chr17 (250 aa)
initn: 769 init1: 485 opt: 714 Z-score: 555.3 bits: 110.3 E(32554): 1.3e-24
Smith-Waterman score: 778; 51.9% identity (68.7% similar) in 262 aa overlap (1-254:1-247)
10 20 30 40 50 60
pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA
:: .: .:.:::::.:::..:: ..:: .: . :..: : . .:::::: ::
CCDS11 MSISGTLSSYYVDSIISHESEDAPPAKFP-SGQY-ASSRQPGHAEHL-EFPSCSFQPKAP
10 20 30 40 50
70 80 90 100 110
pF1KB8 VFSTSWAPVPSQSS----VVYHPY-GPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRH
::..::::. ..: ::::: :: :..::.:::::: . . : : .
CCDS11 VFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP----GQGQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 YALKPDAYPGRRADCGPGE--GRSYPDY-MYGSPGELRDRAPQTLPSPEADALAGSKHKE
:.: . : .::: .. :.: . : :. . : . ::. ::
CCDS11 AAVKAEPLLG-----APGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKE
120 130 140 150 160
180 190 200 210 220 230
pF1KB8 EKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLT
. : .:: :::.::::.::::::::::::::::::::::::::::::.::::.:::.
CCDS11 RP---DQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLS
170 180 190 200 210 220
240 250 260
pF1KB8 ERQVKIWFQNRRMKMKKMNKEKTDKEQS
:::::::::::::::::::::.
CCDS11 ERQVKIWFQNRRMKMKKMNKEQGKE
230 240 250
>>CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7 (272 aa)
initn: 800 init1: 537 opt: 693 Z-score: 539.2 bits: 107.5 E(32554): 1e-23
Smith-Waterman score: 824; 51.3% identity (70.4% similar) in 277 aa overlap (1-258:1-272)
10 20 30 40 50
pF1KB8 MSATGPISNYYVDS-LISHDNEDLLA-SRF-PATGAHPAAARPSGLVPDCSDFPSCSFAP
:..:: ..:::::: :.. : : :. .:. :.: ..: : .. . . :: :::
CCDS54 MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPP--RQAATLAEHPDFSPCSFQS
10 20 30 40 50
60 70 80 90 100
pF1KB8 KPAVFSTSWAPVPSQSS-----VVYH-----PY-GPQPHLGA---DTRYMRTWLEPLSGA
: .::..:: :: . .. .::: :: :: ..: : ::::.:::: ::
CCDS54 KATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 VSFPSFPAGGRHYALKPDAYPGRRADCGPGEGR--SYPDYMYGSPGELRDRAPQTLPSPE
.:: ..:.. : :..::. .::.:: . . : :: ::: :.. :. :
CCDS54 LSFAGLPSS-RPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 ADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDR
.: : .: .::.::.:::.::::::::::::::.:::::::::::::::::::
CCDS54 NNAENESGG--DKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDR
180 190 200 210 220 230
230 240 250 260
pF1KB8 RYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
::::::.:::::::::::::::::::::.::... :
CCDS54 RYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
240 250 260 270
>>CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 (352 aa)
initn: 827 init1: 515 opt: 531 Z-score: 416.4 bits: 85.1 E(32554): 7.1e-17
Smith-Waterman score: 703; 47.8% identity (59.5% similar) in 289 aa overlap (49-257:62-350)
20 30 40 50 60 70
pF1KB8 DNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQS-----
.: ::::::. ::::.::. ::::
CCDS22 EVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAA
40 50 60 70 80 90
80 90 100
pF1KB8 -SVVYHPYGPQPHLGADT----RYMRTWLEPLSG-------------------AVSFPSF
: .:::: : : :.:.. ::.:.:.::: : ::
CCDS22 MSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSG
100 110 120 130 140 150
110 120 130 140
pF1KB8 PAGGRHYALKPD--AYPG-------------------RRADCG---PGEGRSYPDYMYGS
::.::::..::. : :. .:..:. ..: : :.. .:
CCDS22 PANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNS
160 170 180 190 200 210
150 160 170
pF1KB8 --------------PGELRDRAPQTLPSPEADA-----LAGSKHKEE--------KADLD
:: : : : : .: . : . ::: . .::
CCDS22 FLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLD
220 230 240 250 260 270
180 190 200 210 220 230
pF1KB8 PSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKI
:.::.::::::::::::::::::::::::::::::::::::::::::::.::::::::::
CCDS22 PNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKI
280 290 300 310 320 330
240 250 260
pF1KB8 WFQNRRMKMKKMNKEKTDKEQS
::::::::::::.::: :
CCDS22 WFQNRRMKMKKMSKEKCPKGD
340 350
>>CCDS5410.2 HOXA10 gene_id:3206|Hs108|chr7 (410 aa)
initn: 470 init1: 392 opt: 464 Z-score: 365.4 bits: 75.9 E(32554): 4.9e-14
Smith-Waterman score: 472; 40.3% identity (58.8% similar) in 243 aa overlap (25-258:175-402)
10 20 30 40 50
pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPA--AARPSGLVPDCSDFPS
:.. : ..: : : : : :: . .
CCDS54 PQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGT
150 160 170 180 190 200
60 70 80 90 100 110
pF1KB8 CSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAG
: .: :. : : : ... : .::: . : : :.. .:
CCDS54 SSGVPVPGYFRLSQAYGTAKG--YGSGGGGAQQLGAGPFPAQP---PGRGFDLPPALASG
210 220 230 240 250
120 130 140 150 160
pF1KB8 GRHYALKP---DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAP----QTLPSPEADAL
. : : :. : :: : : . . ..: . .. .: .. ::: :.:
CCDS54 SADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSL
260 270 280 290 300 310
170 180 190 200 210 220
pF1KB8 AGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEV
..:: :.: :::. :.: :::::::::.:::::::::::::::::.:: :.
CCDS54 GNSKG--ENA--------ANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEI
320 330 340 350 360
230 240 250 260
pF1KB8 ARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
.: ..::.:::::::::::::.::::.:. .:
CCDS54 SRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS
370 380 390 400 410
>>CCDS8868.1 HOXC10 gene_id:3226|Hs108|chr12 (342 aa)
initn: 439 init1: 418 opt: 449 Z-score: 355.1 bits: 73.7 E(32554): 1.8e-13
Smith-Waterman score: 470; 35.9% identity (60.2% similar) in 259 aa overlap (6-258:95-334)
10 20 30
pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHP
:.:. ....: . : . . :
CCDS88 ALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGP
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB8 AAARPSGLVPD-C---SDFPSCSFA-PKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADT
:: : .:. : . : :. .:. . . .: : .. :. . :. .
CCDS88 EAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRA
130 140 150 160 170 180
100 110 120 130 140
pF1KB8 RYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGEL-
..... :.: :::: : . . .:. ... :: :::.:
CCDS88 EHLES--PQLGGKVSFPETPKSDSQTP-SPNEIKTEQSLAGPK----------GSPSESE
190 200 210 220 230
150 160 170 180 190 200
pF1KB8 RDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEK
..:: . ::. .. .: : .. : ..::. :.: :::::::::.:::::::
CCDS88 KERAKAADSSPD------TSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEK
240 250 260 270 280
210 220 230 240 250 260
pF1KB8 EFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
::::::::::.:: :.....:::.:::::::::::::.::::.:. .:
CCDS88 EFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
290 300 310 320 330 340
>>CCDS2266.1 HOXD10 gene_id:3236|Hs108|chr2 (340 aa)
initn: 485 init1: 411 opt: 431 Z-score: 341.7 bits: 71.2 E(32554): 1e-12
Smith-Waterman score: 435; 39.4% identity (66.2% similar) in 216 aa overlap (43-258:134-332)
20 30 40 50 60 70
pF1KB8 DSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQ
:::. . .: :. : : . . ..
CCDS22 TTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVEN-PEVPVPGYFRLSQTYATGK
110 120 130 140 150 160
80 90 100 110 120 130
pF1KB8 SSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGP
. . :. .:. :..: ... :.: ::.. :.. :. .. : . . .
CCDS22 T----QEYNNSPE-GSSTVMLQ--LNP-RGAAK-PQLSAAQLQMEKKMNEPVSGQEPTKV
170 180 190 200 210
140 150 160 170 180 190
pF1KB8 GEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARST
.. .: :. : : : : .. :::. ..:: : .. ..:..::. :.:
CCDS22 SQVES-PEAKGGLPEERSCLAEVSVSSPEV------QEKESKEEIKSDTPTSNWLTAKSG
220 230 240 250 260
200 210 220 230 240 250
pF1KB8 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNK
:::::::::.:::::::::::::::::.:: :... .:::.:::::::::::::.:::..
CCDS22 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSR
270 280 290 300 310 320
260
pF1KB8 EKTDKEQS
:. .:
CCDS22 ENRIRELTANLTFS
330 340
260 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:29:14 2016 done: Fri Nov 4 16:29:14 2016
Total Scan time: 2.500 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]