Result of FASTA (omim) for
pFN21AB8808
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8808, 355 aa
1>>>pF1KB8808 355 - 355 aa - 355 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8610+/-0.000515; mu= 19.4109+/- 0.032
mean_var=107.8083+/-24.742, 0's: 0 Z-trim(109.2): 689 B-trim: 1767 in 2/47
Lambda= 0.123523
statistics sampled from 16541 (17327) to 16541 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.536), E-opt: 0.2 (0.203), width: 16
Scan time: 6.730
The best scores are: opt bits E(85289)
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 2339 428.4 1.2e-119
NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 1095 206.7 6.6e-53
XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 1095 206.7 6.6e-53
NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 999 189.6 9.3e-48
NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 999 189.6 9.3e-48
NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 995 188.9 1.5e-47
XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 995 188.9 1.5e-47
NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 975 185.3 1.8e-46
NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 957 182.1 1.7e-45
NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 927 176.8 7.1e-44
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 925 176.4 8.7e-44
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 925 176.4 8.7e-44
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 925 176.4 8.7e-44
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 925 176.4 8.7e-44
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 925 176.4 8.9e-44
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 925 176.4 9e-44
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 925 176.5 9.5e-44
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 925 176.5 9.5e-44
NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 918 175.1 2.1e-43
NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 918 175.1 2.1e-43
NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 918 175.1 2.1e-43
NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 781 150.8 4.8e-36
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 738 143.1 9.4e-34
XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 738 143.1 9.4e-34
NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 738 143.1 9.4e-34
NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 738 143.1 9.4e-34
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 738 143.1 9.4e-34
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 738 143.1 9.4e-34
NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 721 140.0 7.9e-33
NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 721 140.0 7.9e-33
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 715 138.9 1.6e-32
NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 699 136.1 1.1e-31
NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 699 136.1 1.2e-31
NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 696 135.6 1.7e-31
NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 696 135.6 1.7e-31
NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 696 135.6 1.7e-31
XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 696 135.6 1.7e-31
NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 688 134.2 4.6e-31
NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 688 134.2 4.6e-31
NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 688 134.2 4.6e-31
NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 688 134.2 4.7e-31
NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 658 128.7 1.7e-29
NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 652 127.7 3.9e-29
NP_116743 (OMIM: 601613) C-X-C chemokine receptor ( 327) 642 125.9 1.3e-28
XP_011532511 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 636 124.9 2.7e-28
XP_011532510 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 636 124.9 2.7e-28
XP_016862925 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 636 124.9 2.7e-28
NP_003956 (OMIM: 608379) C-C chemokine receptor-li ( 344) 636 124.9 2.7e-28
NP_001124382 (OMIM: 608379) C-C chemokine receptor ( 356) 636 124.9 2.8e-28
NP_057641 (OMIM: 606065) atypical chemokine recept ( 350) 628 123.4 7.4e-28
>>NP_005192 (OMIM: 601834) C-C chemokine receptor type 8 (355 aa)
initn: 2339 init1: 2339 opt: 2339 Z-score: 2268.9 bits: 428.4 E(85289): 1.2e-119
Smith-Waterman score: 2339; 99.7% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_005 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY
250 260 270 280 290 300
310 320 330 340 350
pF1KB8 AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
310 320 330 340 350
>>NP_005499 (OMIM: 604836) C-C chemokine receptor type 4 (360 aa)
initn: 1087 init1: 1060 opt: 1095 Z-score: 1070.8 bits: 206.7 E(85289): 6.6e-53
Smith-Waterman score: 1095; 45.5% identity (75.8% similar) in 347 aa overlap (2-345:8-351)
10 20 30 40 50
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNS
: ::: :. ..:: . . .:: : :.. :.:.: .: :.:::.:::::
NP_005 MNPTDIADTTLDESI--YSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNS
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYY
.:.::: :.:::.:::::::::.::::::::.:: :: :::::: .::..: .:
NP_005 VVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 IGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQV
.::::..::. :::.:::::.::::..:..::. .:. ::.: .:..:..: ..:
NP_005 VGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 ASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKT
.: . : . :. .. ::.......:::::.::. :..::: :.. :..:.:..:.
NP_005 YTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCC
::..... ::. : ::.:.:.:::: .: ...:. :.. . : :: ..:: ..:.:::
NP_005 KAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 VNPVIYAFVGEKFKKHLSEIFQKSCSQIF---NYLGRQMPRESCEKSSSCQQHSSRSSSV
.::.:: :.::::.:.. ..: :.: .: .: : . . ::: : .
NP_005 LNPIIYFFLGEKFRKYILQLF-KTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLH
300 310 320 330 340 350
pF1KB8 DYIL
NP_005 DAL
360
>>XP_016861176 (OMIM: 604836) PREDICTED: C-C chemokine r (360 aa)
initn: 1087 init1: 1060 opt: 1095 Z-score: 1070.8 bits: 206.7 E(85289): 6.6e-53
Smith-Waterman score: 1095; 45.5% identity (75.8% similar) in 347 aa overlap (2-345:8-351)
10 20 30 40 50
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNS
: ::: :. ..:: . . .:: : :.. :.:.: .: :.:::.:::::
XP_016 MNPTDIADTTLDESI--YSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNS
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYY
.:.::: :.:::.:::::::::.::::::::.:: :: :::::: .::..: .:
XP_016 VVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 IGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQV
.::::..::. :::.:::::.::::..:..::. .:. ::.: .:..:..: ..:
XP_016 VGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 ASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKT
.: . : . :. .. ::.......:::::.::. :..::: :.. :..:.:..:.
XP_016 YTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCC
::..... ::. : ::.:.:.:::: .: ...:. :.. . : :: ..:: ..:.:::
XP_016 KAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 VNPVIYAFVGEKFKKHLSEIFQKSCSQIF---NYLGRQMPRESCEKSSSCQQHSSRSSSV
.::.:: :.::::.:.. ..: :.: .: .: : . . ::: : .
XP_016 LNPIIYFFLGEKFRKYILQLF-KTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLH
300 310 320 330 340 350
pF1KB8 DYIL
XP_016 DAL
360
>>NP_000570 (OMIM: 601373,609532,610379,612522) C-C chem (352 aa)
initn: 1015 init1: 557 opt: 999 Z-score: 978.4 bits: 189.6 E(85289): 9.3e-48
Smith-Waterman score: 999; 42.0% identity (75.0% similar) in 348 aa overlap (1-346:1-343)
10 20 30 40 50 60
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
::: .. . . .:: : ::. .. . :: .: :.:.:...:: ::::.:
NP_000 MDYQVSSPIYDI-NYYT----SEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
. ::.:.:.::.::::::.:::.:... :: ..: :: ::..::....:.:.:::.:.
NP_000 INCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
.::: :...::::::::::.:::.::. .:.. . .:..:..:..: ..: . .:
NP_000 IFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLH
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 LQCYS-FYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKT-KAIR
: : : .: :: : ..:. ::::..:. ....:: ::. : ::.:..: .:.:
NP_000 YTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 LVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPV
:.. ..:. .:::.:.:.::.:.... . :..:: :..: : .::: ...::::.::.
NP_000 LIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 IYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
:::::::::...: .::: .. : . .:. :..:: .:.
NP_000 IYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
300 310 320 330 340 350
>>NP_001093638 (OMIM: 601373,609532,610379,612522) C-C c (352 aa)
initn: 1015 init1: 557 opt: 999 Z-score: 978.4 bits: 189.6 E(85289): 9.3e-48
Smith-Waterman score: 999; 42.0% identity (75.0% similar) in 348 aa overlap (1-346:1-343)
10 20 30 40 50 60
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
::: .. . . .:: : ::. .. . :: .: :.:.:...:: ::::.:
NP_001 MDYQVSSPIYDI-NYYT----SEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
. ::.:.:.::.::::::.:::.:... :: ..: :: ::..::....:.:.:::.:.
NP_001 INCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
.::: :...::::::::::.:::.::. .:.. . .:..:..:..: ..: . .:
NP_001 IFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLH
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 LQCYS-FYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKT-KAIR
: : : .: :: : ..:. ::::..:. ....:: ::. : ::.:..: .:.:
NP_001 YTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 LVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPV
:.. ..:. .:::.:.:.::.:.... . :..:: :..: : .::: ...::::.::.
NP_001 LIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 IYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
:::::::::...: .::: .. : . .:. :..:: .:.
NP_001 IYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
300 310 320 330 340 350
>>NP_001116868 (OMIM: 601267) C-C chemokine receptor typ (360 aa)
initn: 964 init1: 570 opt: 995 Z-score: 974.5 bits: 188.9 E(85289): 1.5e-47
Smith-Waterman score: 995; 41.5% identity (75.7% similar) in 342 aa overlap (9-346:20-351)
10 20 30 40
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFS
::: :: : ..:: .. : :: .: :.:.:.
NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDY----GAPCHKFDVKQIGAQLLPPLYSLVFIFG
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 LLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVV
..:: ::.:.:. ::::. .::.::::::.:::::....:. .. ..::::..:::.
NP_001 FVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 SGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLL
.:.:.::.....::: :...:::::.::::.:::.::. .:.. . .::.:..:..: .
NP_001 TGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 VFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQ
.: . .::.: : .. . :. : .. :::::..:. :...:: ::. : ::.
NP_001 IFTKCQKEDSVYVCGPYFPR---GWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 NHNKT-KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEII
:..: .:.:... ..:. .:::.:.:.:..:.... . :..: ..:: ::.::: .
NP_001 NEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 SFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMP---RESCEKSSSCQQHS
..::::.::.:::::::::...:: .:.: .. : .: : ::. . .: . :
NP_001 GMTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFC---KQCPVFYRETVDGVTSTNTPS
300 310 320 330 340 350
350
pF1KB8 SRSSSVDYIL
.
NP_001 TGEQEVSAGL
360
>>XP_011532371 (OMIM: 601267) PREDICTED: C-C chemokine r (360 aa)
initn: 964 init1: 570 opt: 995 Z-score: 974.5 bits: 188.9 E(85289): 1.5e-47
Smith-Waterman score: 995; 41.5% identity (75.7% similar) in 342 aa overlap (9-346:20-351)
10 20 30 40
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFS
::: :: : ..:: .. : :: .: :.:.:.
XP_011 MLSTSRSRFIRNTNESGEEVTTFFDYDY----GAPCHKFDVKQIGAQLLPPLYSLVFIFG
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 LLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVV
..:: ::.:.:. ::::. .::.::::::.:::::....:. .. ..::::..:::.
XP_011 FVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 SGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLL
.:.:.::.....::: :...:::::.::::.:::.::. .:.. . .::.:..:..: .
XP_011 TGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 VFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQ
.: . .::.: : .. . :. : .. :::::..:. :...:: ::. : ::.
XP_011 IFTKCQKEDSVYVCGPYFPR---GWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 NHNKT-KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEII
:..: .:.:... ..:. .:::.:.:.:..:.... . :..: ..:: ::.::: .
XP_011 NEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 SFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMP---RESCEKSSSCQQHS
..::::.::.:::::::::...:: .:.: .. : .: : ::. . .: . :
XP_011 GMTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFC---KQCPVFYRETVDGVTSTNTPS
300 310 320 330 340 350
350
pF1KB8 SRSSSVDYIL
.
XP_011 TGEQEVSAGL
360
>>NP_001286 (OMIM: 601159) C-C chemokine receptor type 1 (355 aa)
initn: 942 init1: 429 opt: 975 Z-score: 955.3 bits: 185.3 E(85289): 1.8e-46
Smith-Waterman score: 975; 42.6% identity (76.0% similar) in 329 aa overlap (11-337:12-335)
10 20 30 40 50
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFSLLGNSLVILV
:.:.. : : ..::. .. : :: .: :.::..:.:: ::.::
NP_001 METPNTTEDYDTTTEFDYGD--ATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLV
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LVVCKKLRSITDVYLLNLALSDLLFVFSFPFQT-YYLLDQWVFGTVMCKVVSGFYYIGFY
:: :.:...:..::::::.:::::.:..:: : : :.:::: .:::..::::: :.:
NP_001 LVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 SSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASED
: .::: :...:::::.::::.::..::. .:. . .: ::.:..: : : .. :
NP_001 SEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 GVLQCYSFYNQQTLK-WKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAI
: . ...:. ::.: .:.:..::..:. ....:: :.. : : :..:.::.
NP_001 THHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 RLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNP
::.....: .:::.:.:...... .... . : :..: :..:::.:..:::::::
NP_001 RLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 VIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
::::::::.:.:.: ..:.. .. .: . .: : ..
NP_001 VIYAFVGERFRKYLRQLFHR---RVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
300 310 320 330 340 350
>>NP_001116513 (OMIM: 601267) C-C chemokine receptor typ (374 aa)
initn: 898 init1: 570 opt: 957 Z-score: 937.7 bits: 182.1 E(85289): 1.7e-45
Smith-Waterman score: 957; 43.5% identity (78.4% similar) in 301 aa overlap (9-308:20-313)
10 20 30 40
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCDGELIQTNGKLLLAVFYCLLFVFS
::: :: : ..:: .. : :: .: :.:.:.
NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDY----GAPCHKFDVKQIGAQLLPPLYSLVFIFG
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 LLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVV
..:: ::.:.:. ::::. .::.::::::.:::::....:. .. ..::::..:::.
NP_001 FVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 SGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLL
.:.:.::.....::: :...:::::.::::.:::.::. .:.. . .::.:..:..: .
NP_001 TGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 VFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQ
.: . .::.: : .. . :. : .. :::::..:. :...:: ::. : ::.
NP_001 IFTKCQKEDSVYVCGPYFPRG---WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 NHNKT-KAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEII
:..: .:.:... ..:. .:::.:.:.:..:.... . :..: ..:: ::.::: .
NP_001 NEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 SFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRS
..::::.::.:::::::::.
NP_001 GMTHCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDG
300 310 320 330 340 350
>>NP_001164645 (OMIM: 601470,607339,609423,613784) CX3C (387 aa)
initn: 861 init1: 466 opt: 927 Z-score: 908.6 bits: 176.8 E(85289): 7.1e-44
Smith-Waterman score: 927; 39.8% identity (75.6% similar) in 349 aa overlap (3-350:31-372)
10 20 30
pF1KB8 MDYTLDLSVTTVTDYYYPDIFSSPCD-GELIQ
.:.: .::. . : .. : :...
NP_001 MREPLEAFKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIV-
10 20 30 40 50
40 50 60 70 80 90
pF1KB8 TNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQ
. : ..:..:: ..:...:.:: ::...:. :: .:.::.::::::::::::: ..::
NP_001 VFGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFW
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB8 TYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGT
:.::... . ..::: ...:..:::..:.::::..:.:::::.: :. ... ::.. :.
NP_001 THYLINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGV
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 TLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPF
:. :.:: .::... : ..: . .:. : : :. : .. : . :.::.:.:.
NP_001 TISLGVWAAAILVAAPQFMFTK-QKENECLGDYPEVLQEI--WPVLRNVETNFLGFLLPL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 TIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDG
:. .::..:.. : :.::.:.:::.:.:.:::. .:::.:.::..:: .:. . .. .
NP_001 LIMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB8 CSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMP
:.. ..: : ::: ..:.:::.::.::::.::::...: ... : : .. ::..
NP_001 CDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGK-CLAVL--CGRSVH
300 310 320 330 340 350
340 350
pF1KB8 RESCEKSSSCQQHSSRSSSVDYIL
. . :. ..:.: ::
NP_001 VDFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL
360 370 380
355 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:45:37 2016 done: Fri Nov 4 15:45:38 2016
Total Scan time: 6.730 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]