Result of FASTA (omim) for
pFN21AB8310
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8310, 403 aa
1>>>pF1KB8310 403 - 403 aa - 403 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2561+/-0.000529; mu= -6.2590+/- 0.032
mean_var=498.4319+/-111.608, 0's: 0 Z-trim(118.3): 2038 B-trim: 33 in 1/52
Lambda= 0.057448
statistics sampled from 28503 (31191) to 28503 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.366), width: 16
Scan time: 5.760
The best scores are: opt bits E(85289)
NP_003591 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 2700 238.8 1.8e-62
NP_001310234 (OMIM: 603072) aurora kinase A [Homo ( 403) 2700 238.8 1.8e-62
NP_940836 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 2700 238.8 1.8e-62
NP_940835 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 2700 238.8 1.8e-62
NP_001310233 (OMIM: 603072) aurora kinase A [Homo ( 403) 2700 238.8 1.8e-62
NP_940838 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 2700 238.8 1.8e-62
NP_940837 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 2700 238.8 1.8e-62
NP_940839 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 2700 238.8 1.8e-62
XP_016883524 (OMIM: 603072) PREDICTED: aurora kina ( 403) 2700 238.8 1.8e-62
NP_001310232 (OMIM: 603072) aurora kinase A [Homo ( 403) 2700 238.8 1.8e-62
XP_016883523 (OMIM: 603072) PREDICTED: aurora kina ( 437) 2700 238.8 1.9e-62
NP_001300881 (OMIM: 604970) aurora kinase B isofor ( 304) 1351 126.8 7e-29
NP_001271455 (OMIM: 604970) aurora kinase B isofor ( 345) 1351 126.9 7.5e-29
NP_001300880 (OMIM: 604970) aurora kinase B isofor ( 303) 1348 126.6 8.3e-29
NP_001243763 (OMIM: 604970) aurora kinase B isofor ( 303) 1348 126.6 8.3e-29
XP_011522374 (OMIM: 604970) PREDICTED: aurora kina ( 303) 1348 126.6 8.3e-29
XP_016880796 (OMIM: 604970) PREDICTED: aurora kina ( 303) 1348 126.6 8.3e-29
NP_004208 (OMIM: 604970) aurora kinase B isoform 1 ( 344) 1348 126.6 8.9e-29
NP_001300879 (OMIM: 604970) aurora kinase B isofor ( 344) 1348 126.6 8.9e-29
NP_001015878 (OMIM: 243060,603495) aurora kinase C ( 309) 1316 123.9 5.3e-28
NP_001015879 (OMIM: 243060,603495) aurora kinase C ( 290) 1311 123.5 6.8e-28
NP_003151 (OMIM: 243060,603495) aurora kinase C is ( 275) 1309 123.3 7.3e-28
XP_016880797 (OMIM: 604970) PREDICTED: aurora kina ( 271) 1004 98.0 3e-20
NP_001300882 (OMIM: 604970) aurora kinase B isofor ( 312) 1004 98.1 3.2e-20
XP_011522372 (OMIM: 604970) PREDICTED: aurora kina ( 312) 1004 98.1 3.2e-20
NP_001300883 (OMIM: 604970) aurora kinase B isofor ( 192) 796 80.5 3.7e-15
XP_016880799 (OMIM: 604970) PREDICTED: aurora kina ( 192) 796 80.5 3.7e-15
XP_016880798 (OMIM: 604970) PREDICTED: aurora kina ( 192) 796 80.5 3.7e-15
XP_016880800 (OMIM: 604970) PREDICTED: aurora kina ( 192) 796 80.5 3.7e-15
NP_001300884 (OMIM: 604970) aurora kinase B isofor ( 176) 779 79.1 9.4e-15
XP_005262758 (OMIM: 605031,616171) PREDICTED: seri ( 936) 663 70.5 2e-11
XP_016863152 (OMIM: 605031,616171) PREDICTED: seri ( 937) 663 70.5 2e-11
NP_055079 (OMIM: 605031,616171) serine/threonine-p ( 970) 663 70.5 2e-11
XP_016863151 (OMIM: 605031,616171) PREDICTED: seri ( 971) 663 70.5 2e-11
NP_001094064 (OMIM: 612760) SNF-related serine/thr ( 765) 593 64.5 9.8e-10
XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ( 765) 593 64.5 9.8e-10
NP_060189 (OMIM: 612760) SNF-related serine/threon ( 765) 593 64.5 9.8e-10
NP_001271293 (OMIM: 613472) serine/threonine-prote ( 470) 580 63.2 1.6e-09
NP_001092906 (OMIM: 613472) serine/threonine-prote ( 472) 580 63.2 1.6e-09
NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 576 62.9 2e-09
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 579 63.3 2.1e-09
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 579 63.3 2.1e-09
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 579 63.3 2.1e-09
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 579 63.4 2.2e-09
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 579 63.4 2.2e-09
NP_001248745 (OMIM: 605213) 3-phosphoinositide-dep ( 454) 572 62.5 2.4e-09
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 575 62.9 2.5e-09
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 575 63.0 2.6e-09
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 575 63.0 2.6e-09
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 575 63.0 2.6e-09
>>NP_003591 (OMIM: 603072) aurora kinase A [Homo sapiens (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_003 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_003 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>NP_001310234 (OMIM: 603072) aurora kinase A [Homo sapi (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_001 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>NP_940836 (OMIM: 603072) aurora kinase A [Homo sapiens (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_940 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_940 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>NP_940835 (OMIM: 603072) aurora kinase A [Homo sapiens (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_940 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_940 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>NP_001310233 (OMIM: 603072) aurora kinase A [Homo sapi (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_001 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>NP_940838 (OMIM: 603072) aurora kinase A [Homo sapiens (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_940 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_940 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>NP_940837 (OMIM: 603072) aurora kinase A [Homo sapiens (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_940 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_940 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>NP_940839 (OMIM: 603072) aurora kinase A [Homo sapiens (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_940 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_940 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>XP_016883524 (OMIM: 603072) PREDICTED: aurora kinase A (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_016 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
>>NP_001310232 (OMIM: 603072) aurora kinase A [Homo sapi (403 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1242.5 bits: 238.8 E(85289): 1.8e-62
Smith-Waterman score: 2700; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB8 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_001 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
310 320 330 340 350 360
370 380 390 400
pF1KB8 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
:::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
370 380 390 400
403 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:36:39 2016 done: Fri Nov 4 11:36:40 2016
Total Scan time: 5.760 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]