Result of FASTA (omim) for
pFN21AB8221
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8221, 248 aa
1>>>pF1KB8221 248 - 248 aa - 248 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4143+/-0.000288; mu= 7.0546+/- 0.018
mean_var=155.1264+/-31.527, 0's: 0 Z-trim(122.2): 16 B-trim: 0 in 0/55
Lambda= 0.102975
statistics sampled from 39927 (39943) to 39927 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.468), width: 16
Scan time: 6.530
The best scores are: opt bits E(85289)
NP_009027 (OMIM: 118960) clathrin light chain A is ( 248) 1675 259.6 3.9e-69
NP_001070145 (OMIM: 118960) clathrin light chain A ( 236) 1221 192.1 7.5e-49
XP_016869746 (OMIM: 118960) PREDICTED: clathrin li ( 170) 1130 178.5 6.8e-45
NP_001824 (OMIM: 118960) clathrin light chain A is ( 218) 1127 178.1 1.1e-44
NP_001171690 (OMIM: 118960) clathrin light chain A ( 168) 1094 173.1 2.8e-43
NP_001171689 (OMIM: 118960) clathrin light chain A ( 230) 1094 173.2 3.5e-43
NP_001298133 (OMIM: 118960) clathrin light chain A ( 196) 833 134.4 1.5e-31
NP_009028 (OMIM: 118970) clathrin light chain B is ( 229) 648 107.0 3.1e-23
NP_001298132 (OMIM: 118960) clathrin light chain A ( 140) 582 97.0 1.9e-20
NP_001825 (OMIM: 118970) clathrin light chain B is ( 211) 581 97.0 2.9e-20
XP_016869747 (OMIM: 118960) PREDICTED: clathrin li ( 152) 549 92.1 6e-19
NP_001171691 (OMIM: 118960) clathrin light chain A ( 166) 532 89.6 3.7e-18
NP_001298134 (OMIM: 118960) clathrin light chain A ( 178) 524 88.4 8.9e-18
XP_016864515 (OMIM: 118970) PREDICTED: clathrin li ( 144) 409 71.3 1.1e-12
NP_001298135 (OMIM: 118960) clathrin light chain A ( 101) 369 65.2 4.9e-11
XP_016864516 (OMIM: 118970) PREDICTED: clathrin li ( 134) 200 40.2 0.0022
>>NP_009027 (OMIM: 118960) clathrin light chain A isofor (248 aa)
initn: 1675 init1: 1675 opt: 1675 Z-score: 1362.3 bits: 259.6 E(85289): 3.9e-69
Smith-Waterman score: 1675; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)
10 20 30 40 50 60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
190 200 210 220 230 240
pF1KB8 LKQAPLVH
::::::::
NP_009 LKQAPLVH
>>NP_001070145 (OMIM: 118960) clathrin light chain A iso (236 aa)
initn: 1573 init1: 1221 opt: 1221 Z-score: 998.1 bits: 192.1 E(85289): 7.5e-49
Smith-Waterman score: 1553; 95.2% identity (95.2% similar) in 248 aa overlap (1-248:1-236)
10 20 30 40 50 60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
190 200 210 220
pF1KB8 LKQAPLVH
::::::::
NP_001 LKQAPLVH
230
>>XP_016869746 (OMIM: 118960) PREDICTED: clathrin light (170 aa)
initn: 1130 init1: 1130 opt: 1130 Z-score: 926.9 bits: 178.5 E(85289): 6.8e-45
Smith-Waterman score: 1130; 100.0% identity (100.0% similar) in 170 aa overlap (79-248:1-170)
50 60 70 80 90 100
pF1KB8 DEAFAILDGGAPGPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPE
::::::::::::::::::::::::::::::
XP_016 MNGEYYQESNGPTDSYAAISQVDRLQSEPE
10 20 30
110 120 130 140 150 160
pF1KB8 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAF
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 YKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA
100 110 120 130 140 150
230 240
pF1KB8 KDVSRMRSVLISLKQAPLVH
::::::::::::::::::::
XP_016 KDVSRMRSVLISLKQAPLVH
160 170
>>NP_001824 (OMIM: 118960) clathrin light chain A isofor (218 aa)
initn: 1127 init1: 1127 opt: 1127 Z-score: 923.1 bits: 178.1 E(85289): 1.1e-44
Smith-Waterman score: 1397; 87.9% identity (87.9% similar) in 248 aa overlap (1-248:1-218)
10 20 30 40 50 60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
::::::::::::::::::::::::::::::::::::::::::
NP_001 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNR------------------
130 140 150 160
190 200 210 220 230 240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
170 180 190 200 210
pF1KB8 LKQAPLVH
::::::::
NP_001 LKQAPLVH
>>NP_001171690 (OMIM: 118960) clathrin light chain A iso (168 aa)
initn: 1094 init1: 1094 opt: 1094 Z-score: 898.1 bits: 173.1 E(85289): 2.8e-43
Smith-Waterman score: 1094; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:1-161)
10 20 30 40 50 60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
:::::::::::::::::::::::::::::::::::::::::
NP_001 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNSRRSLCK
130 140 150 160
190 200 210 220 230 240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
>>NP_001171689 (OMIM: 118960) clathrin light chain A iso (230 aa)
initn: 1534 init1: 1094 opt: 1094 Z-score: 896.2 bits: 173.2 E(85289): 3.5e-43
Smith-Waterman score: 1501; 92.3% identity (92.3% similar) in 248 aa overlap (1-248:1-230)
10 20 30 40 50 60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
:::::::::::::::::::::::::::::::::::::::::
NP_001 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNS------------------
130 140 150 160
190 200 210 220 230 240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
170 180 190 200 210 220
pF1KB8 LKQAPLVH
::::::::
NP_001 LKQAPLVH
230
>>NP_001298133 (OMIM: 118960) clathrin light chain A iso (196 aa)
initn: 826 init1: 826 opt: 833 Z-score: 687.6 bits: 134.4 E(85289): 1.5e-31
Smith-Waterman score: 1218; 79.0% identity (79.0% similar) in 248 aa overlap (1-248:1-196)
10 20 30 40 50 60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
::::::::::::
NP_001 GPQPHGEPPGGP------------------------------------------------
70
130 140 150 160 170 180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----DANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
80 90 100 110 120
190 200 210 220 230 240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
130 140 150 160 170 180
pF1KB8 LKQAPLVH
::::::::
NP_001 LKQAPLVH
190
>>NP_009028 (OMIM: 118970) clathrin light chain B isofor (229 aa)
initn: 677 init1: 490 opt: 648 Z-score: 538.2 bits: 107.0 E(85289): 3.1e-23
Smith-Waterman score: 893; 61.2% identity (79.3% similar) in 227 aa overlap (21-246:13-227)
10 20 30 40 50 60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
.:. :.:::::::::::::::::::::::.:. :.
NP_009 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
10 20 30 40 50
70 80 90 100 110
pF1KB8 GPQPHGEPPG-GPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
.: : : : . . ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_009 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGY
::. ::: :. : ::.::: :.:::: ::.::..:.: :::.::.:::.:: ::.:::
NP_009 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 VTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLI
: :.:::::.. : .::::::.::.::::::::::: :::::.::::.
NP_009 V------------ASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM
180 190 200 210 220
240
pF1KB8 SLKQAPLVH
::::.::
NP_009 SLKQTPLSR
>>NP_001298132 (OMIM: 118960) clathrin light chain A iso (140 aa)
initn: 582 init1: 582 opt: 582 Z-score: 488.1 bits: 97.0 E(85289): 1.9e-20
Smith-Waterman score: 852; 82.4% identity (82.4% similar) in 170 aa overlap (79-248:1-140)
50 60 70 80 90 100
pF1KB8 DEAFAILDGGAPGPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPE
::::::::::::::::::::::::::::::
NP_001 MNGEYYQESNGPTDSYAAISQVDRLQSEPE
10 20 30
110 120 130 140 150 160
pF1KB8 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNR------
40 50 60 70 80
170 180 190 200 210 220
pF1KB8 YKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA
::::::::::::::::::::::::::::::::::::
NP_001 ------------------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA
90 100 110 120
230 240
pF1KB8 KDVSRMRSVLISLKQAPLVH
::::::::::::::::::::
NP_001 KDVSRMRSVLISLKQAPLVH
130 140
>>NP_001825 (OMIM: 118970) clathrin light chain B isofor (211 aa)
initn: 625 init1: 422 opt: 581 Z-score: 484.9 bits: 97.0 E(85289): 2.9e-20
Smith-Waterman score: 761; 55.5% identity (71.8% similar) in 227 aa overlap (21-246:13-209)
10 20 30 40 50 60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
.:. :.:::::::::::::::::::::::.:. :.
NP_001 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
10 20 30 40 50
70 80 90 100 110
pF1KB8 GPQPHGEPPG-GPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
.: : : : . . ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_001 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGY
::. ::: :. : ::.::: :.:::: ::.::..:.: :::
NP_001 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR-----------------
120 130 140 150
180 190 200 210 220 230
pF1KB8 VTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLI
:.:::::.. : .::::::.::.::::::::::: :::::.::::.
NP_001 -------------ASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM
160 170 180 190 200
240
pF1KB8 SLKQAPLVH
::::.::
NP_001 SLKQTPLSR
210
248 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:41:44 2016 done: Fri Nov 4 10:41:45 2016
Total Scan time: 6.530 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]