Result of FASTA (omim) for
pFN21AB8207
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8207, 292 aa
1>>>pF1KB8207 292 - 292 aa - 292 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.4607+/-0.000632; mu= -21.6651+/- 0.037
mean_var=689.7793+/-154.269, 0's: 0 Z-trim(115.9): 1454 B-trim: 0 in 0/58
Lambda= 0.048834
statistics sampled from 24561 (26598) to 24561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.312), width: 16
Scan time: 6.510
The best scores are: opt bits E(85289)
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 1994 155.9 8.4e-38
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 1216 101.1 2.7e-21
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 1183 98.8 1.4e-20
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 1134 95.7 2.1e-19
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1134 95.7 2.1e-19
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 1134 95.7 2.1e-19
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1134 95.7 2.1e-19
NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 1133 95.6 2.1e-19
XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1133 95.6 2.1e-19
XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1133 95.6 2.1e-19
XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1133 95.6 2.1e-19
XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1133 95.6 2.1e-19
XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1133 95.6 2.1e-19
NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 1133 95.6 2.1e-19
XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 1133 95.6 2.1e-19
XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 1133 95.6 2.2e-19
XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 1133 95.6 2.2e-19
XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 1133 95.6 2.2e-19
NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 1133 95.6 2.3e-19
XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 1133 95.6 2.3e-19
NP_001157882 (OMIM: 123831,616342) cyclin-dependen ( 260) 1108 93.4 4.8e-19
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 1097 92.7 9e-19
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 1097 92.7 9e-19
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 1097 92.7 9e-19
NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1099 93.1 1.1e-18
NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1099 93.1 1.1e-18
NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 1099 93.2 1.1e-18
XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 1099 93.2 1.2e-18
XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 1099 93.2 1.2e-18
NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 1037 88.7 2.1e-17
XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 1037 88.7 2.1e-17
XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 1037 88.7 2.2e-17
NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 1037 88.7 2.2e-17
NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469) 1037 88.8 2.2e-17
XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 1037 88.8 2.2e-17
XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384) 974 84.2 4.3e-16
NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384) 974 84.2 4.3e-16
NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400) 974 84.2 4.4e-16
XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412) 974 84.3 4.5e-16
NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429) 974 84.3 4.6e-16
XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435) 974 84.3 4.6e-16
NP_001274066 (OMIM: 610679) cyclin-dependent kinas ( 340) 946 82.2 1.6e-15
>>NP_004926 (OMIM: 123831,616342) cyclin-dependent-like (292 aa)
initn: 1994 init1: 1994 opt: 1994 Z-score: 799.6 bits: 155.9 E(85289): 8.4e-38
Smith-Waterman score: 1994; 100.0% identity (100.0% similar) in 292 aa overlap (1-292:1-292)
10 20 30 40 50 60
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP
190 200 210 220 230 240
250 260 270 280 290
pF1KB8 MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
250 260 270 280 290
>>NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 [Ho (305 aa)
initn: 585 init1: 585 opt: 1216 Z-score: 503.2 bits: 101.1 E(85289): 2.7e-21
Smith-Waterman score: 1216; 61.4% identity (85.3% similar) in 293 aa overlap (1-291:1-291)
10 20 30 40 50 60
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
:. ..:.:::::::::.:.::::::: ..::::..::: . :::::.:.::: :::::::
NP_001 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDP-EIVKSFLFQLLKGLGFCHS
::::: ::.:...:: ::::: .::::::.:: :. : ...::.:::::.:..::::
NP_001 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY
. :.::::::::::::. : .::::::::::::.:.: :. :::::::: :..:.:.:.:
NP_001 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK-P
.:..:.:: ::::::... . ::::.. ::: ::::.::::.:. ::..:.:::::
NP_001 TTAVDIWSIGCIFAEMVTR-KALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS
190 200 210 220 230
240 250 260 270 280 290
pF1KB8 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
.: . . .: ..::.:. :::::..::. .: :::.:. :: :::::. :
NP_001 FPKW-TRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQY
240 250 260 270 280 290
NP_001 VLQRFRH
300
>>NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 iso (298 aa)
initn: 1004 init1: 524 opt: 1183 Z-score: 490.7 bits: 98.8 E(85289): 1.4e-20
Smith-Waterman score: 1183; 59.9% identity (82.0% similar) in 294 aa overlap (1-292:1-292)
10 20 30 40 50 60
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
:....:.:::::::::.:.::.:. : :.::::..::: . :::::.:.::: :::::.:
NP_001 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDP-EIVKSFLFQLLKGLGFCHS
:::.: ::.:...:: ::::: :::::..:. : ..::.:::::.::.::::
NP_001 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY
. :::::::::::::: .: .::::::::::::.::: :. :::::::: :..:.: : :
NP_001 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP-
::..:.:: ::::::... : ::::.. ::: :::: :::: : ::..:..:::::
NP_001 STAVDIWSLGCIFAEMVTR-RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPS
190 200 210 220 230
240 250 260 270 280 290
pF1KB8 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
.: . : .. .::: :. ::.::...:. .: .::::. :: ::.:.: :
NP_001 FPKW-ARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
240 250 260 270 280 290
>>NP_002586 (OMIM: 603440) cyclin-dependent kinase 17 is (523 aa)
initn: 1050 init1: 779 opt: 1134 Z-score: 469.4 bits: 95.7 E(85289): 2.1e-19
Smith-Waterman score: 1134; 56.3% identity (84.6% similar) in 293 aa overlap (1-291:189-478)
10 20 30
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
:. : ::::.:::::.::.:.... :...:
NP_002 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
:::..::. . ::.: .:.::. :::.::: ::: :::..:.::.::::::. :.:::.:
NP_002 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
220 230 240 250 260 270
100 110 120 130 140 150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
.:.:.. .. . :: ::.:.:.::..:: :.::::::::::::::..:::::::::::::
NP_002 MDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA
280 290 300 310 320 330
160 170 180 190 200 210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
..:.. :: :::::::::::::.:.. :::.::::..:::: :.:. :::::::. :.:
NP_002 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPGSTVED
340 350 360 370 380 390
220 230 240 250 260
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
.:. ::::::::..: ::.... ..: : : : :.: .:.:.. : .:. ..:.
NP_002 ELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQP-LINHAPRLDSEGIELITKFLQ
400 410 420 430 440 450
270 280 290
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP
. .:.:::::..: :: .. :
NP_002 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
460 470 480 490 500 510
>>XP_016874894 (OMIM: 603440) PREDICTED: cyclin-dependen (523 aa)
initn: 1050 init1: 779 opt: 1134 Z-score: 469.4 bits: 95.7 E(85289): 2.1e-19
Smith-Waterman score: 1134; 56.3% identity (84.6% similar) in 293 aa overlap (1-291:189-478)
10 20 30
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
:. : ::::.:::::.::.:.... :...:
XP_016 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
:::..::. . ::.: .:.::. :::.::: ::: :::..:.::.::::::. :.:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
220 230 240 250 260 270
100 110 120 130 140 150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
.:.:.. .. . :: ::.:.:.::..:: :.::::::::::::::..:::::::::::::
XP_016 MDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA
280 290 300 310 320 330
160 170 180 190 200 210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
..:.. :: :::::::::::::.:.. :::.::::..:::: :.:. :::::::. :.:
XP_016 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPGSTVED
340 350 360 370 380 390
220 230 240 250 260
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
.:. ::::::::..: ::.... ..: : : : :.: .:.:.. : .:. ..:.
XP_016 ELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQP-LINHAPRLDSEGIELITKFLQ
400 410 420 430 440 450
270 280 290
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP
. .:.:::::..: :: .. :
XP_016 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
460 470 480 490 500 510
>>NP_001163935 (OMIM: 603440) cyclin-dependent kinase 17 (523 aa)
initn: 1050 init1: 779 opt: 1134 Z-score: 469.4 bits: 95.7 E(85289): 2.1e-19
Smith-Waterman score: 1134; 56.3% identity (84.6% similar) in 293 aa overlap (1-291:189-478)
10 20 30
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
:. : ::::.:::::.::.:.... :...:
NP_001 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
:::..::. . ::.: .:.::. :::.::: ::: :::..:.::.::::::. :.:::.:
NP_001 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
220 230 240 250 260 270
100 110 120 130 140 150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
.:.:.. .. . :: ::.:.:.::..:: :.::::::::::::::..:::::::::::::
NP_001 MDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA
280 290 300 310 320 330
160 170 180 190 200 210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
..:.. :: :::::::::::::.:.. :::.::::..:::: :.:. :::::::. :.:
NP_001 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPGSTVED
340 350 360 370 380 390
220 230 240 250 260
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
.:. ::::::::..: ::.... ..: : : : :.: .:.:.. : .:. ..:.
NP_001 ELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQP-LINHAPRLDSEGIELITKFLQ
400 410 420 430 440 450
270 280 290
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP
. .:.:::::..: :: .. :
NP_001 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGVFV
460 470 480 490 500 510
>>XP_016874895 (OMIM: 603440) PREDICTED: cyclin-dependen (523 aa)
initn: 1050 init1: 779 opt: 1134 Z-score: 469.4 bits: 95.7 E(85289): 2.1e-19
Smith-Waterman score: 1134; 56.3% identity (84.6% similar) in 293 aa overlap (1-291:189-478)
10 20 30
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
:. : ::::.:::::.::.:.... :...:
XP_016 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
160 170 180 190 200 210
40 50 60 70 80 90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
:::..::. . ::.: .:.::. :::.::: ::: :::..:.::.::::::. :.:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
220 230 240 250 260 270
100 110 120 130 140 150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
.:.:.. .. . :: ::.:.:.::..:: :.::::::::::::::..:::::::::::::
XP_016 MDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARA
280 290 300 310 320 330
160 170 180 190 200 210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
..:.. :: :::::::::::::.:.. :::.::::..:::: :.:. :::::::. :.:
XP_016 KSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMAS-GRPLFPGSTVED
340 350 360 370 380 390
220 230 240 250 260
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
.:. ::::::::..: ::.... ..: : : : :.: .:.:.. : .:. ..:.
XP_016 ELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQP-LINHAPRLDSEGIELITKFLQ
400 410 420 430 440 450
270 280 290
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP
. .:.:::::..: :: .. :
XP_016 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
460 470 480 490 500 510
>>NP_006192 (OMIM: 311550) cyclin-dependent kinase 16 is (496 aa)
initn: 1044 init1: 774 opt: 1133 Z-score: 469.3 bits: 95.6 E(85289): 2.1e-19
Smith-Waterman score: 1133; 58.0% identity (84.7% similar) in 288 aa overlap (1-286:162-446)
10 20 30
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
.. : ::.:.:::::.::.:.:.. : ..:
NP_006 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
140 150 160 170 180 190
40 50 60 70 80 90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
:::..::. . ::.: .:.::. :::.::: ::: :::..:..:.::::::. :.:::.:
NP_006 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
200 210 220 230 240 250
100 110 120 130 140 150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
.:.:.. .. . :: ::::::.::..:: ..::::::::::::::. :::::::::::::
NP_006 LDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARA
260 270 280 290 300 310
160 170 180 190 200 210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
.::.. :: :::::::::::.:.:. :::.::::..:::: :.:. :::::::. :..
NP_006 KSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMAT-GRPLFPGSTVEE
320 330 340 350 360
220 230 240 250 260
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
::. :::.::::::: ::.. . ..: : : : : .:.. .:.:.. : ::: .::.
NP_006 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAE-ALLSHAPRLDSDGADLLTKLLQ
370 380 390 400 410 420
270 280 290
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP
. .:::::.:..::.:
NP_006 FEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPA
430 440 450 460 470 480
>>XP_016885060 (OMIM: 311550) PREDICTED: cyclin-dependen (496 aa)
initn: 1044 init1: 774 opt: 1133 Z-score: 469.3 bits: 95.6 E(85289): 2.1e-19
Smith-Waterman score: 1133; 58.0% identity (84.7% similar) in 288 aa overlap (1-286:162-446)
10 20 30
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
.. : ::.:.:::::.::.:.:.. : ..:
XP_016 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
140 150 160 170 180 190
40 50 60 70 80 90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
:::..::. . ::.: .:.::. :::.::: ::: :::..:..:.::::::. :.:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
200 210 220 230 240 250
100 110 120 130 140 150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
.:.:.. .. . :: ::::::.::..:: ..::::::::::::::. :::::::::::::
XP_016 LDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARA
260 270 280 290 300 310
160 170 180 190 200 210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
.::.. :: :::::::::::.:.:. :::.::::..:::: :.:. :::::::. :..
XP_016 KSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMAT-GRPLFPGSTVEE
320 330 340 350 360
220 230 240 250 260
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
::. :::.::::::: ::.. . ..: : : : : .:.. .:.:.. : ::: .::.
XP_016 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAE-ALLSHAPRLDSDGADLLTKLLQ
370 380 390 400 410 420
270 280 290
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP
. .:::::.:..::.:
XP_016 FEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPA
430 440 450 460 470 480
>>XP_016885062 (OMIM: 311550) PREDICTED: cyclin-dependen (496 aa)
initn: 1044 init1: 774 opt: 1133 Z-score: 469.3 bits: 95.6 E(85289): 2.1e-19
Smith-Waterman score: 1133; 58.0% identity (84.7% similar) in 288 aa overlap (1-286:162-446)
10 20 30
pF1KB8 MQKYEKLEKIGEGTYGTVFKAKNRETHEIV
.. : ::.:.:::::.::.:.:.. : ..:
XP_016 EKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLV
140 150 160 170 180 190
40 50 60 70 80 90
pF1KB8 ALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKY
:::..::. . ::.: .:.::. :::.::: ::: :::..:..:.::::::. :.:::.:
XP_016 ALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY
200 210 220 230 240 250
100 110 120 130 140 150
pF1KB8 FDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARA
.:.:.. .. . :: ::::::.::..:: ..::::::::::::::. :::::::::::::
XP_016 LDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARA
260 270 280 290 300 310
160 170 180 190 200 210
pF1KB8 FGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDD
.::.. :: :::::::::::.:.:. :::.::::..:::: :.:. :::::::. :..
XP_016 KSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMAT-GRPLFPGSTVEE
320 330 340 350 360
220 230 240 250 260
pF1KB8 QLKRIFRLLGTPTEEQWPSMTKLPDYKPY--PMYPATTSLVNVVPKLNATGRDLLQNLLK
::. :::.::::::: ::.. . ..: : : : : .:.. .:.:.. : ::: .::.
XP_016 QLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAE-ALLSHAPRLDSDGADLLTKLLQ
370 380 390 400 410 420
270 280 290
pF1KB8 CNPVQRISAEEALQHPYFSDFCPP
. .:::::.:..::.:
XP_016 FEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPA
430 440 450 460 470 480
292 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:33:41 2016 done: Fri Nov 4 10:33:42 2016
Total Scan time: 6.510 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]