Result of FASTA (omim) for
pFN21AB8162
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8162, 359 aa
1>>>pF1KB8162 359 - 359 aa - 359 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1160+/-0.000503; mu= 20.9880+/- 0.032
mean_var=227.5559+/-59.281, 0's: 0 Z-trim(113.6): 101 B-trim: 2691 in 2/48
Lambda= 0.085022
statistics sampled from 22949 (23070) to 22949 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.27), width: 16
Scan time: 5.850
The best scores are: opt bits E(85289)
NP_002887 (OMIM: 602571) RNA-binding protein 4 iso ( 364) 2134 275.2 1.6e-73
NP_001185773 (OMIM: 602571) RNA-binding protein 4 ( 173) 902 123.5 3.6e-28
NP_001185772 (OMIM: 602571) RNA-binding protein 4 ( 143) 896 122.6 5.5e-28
NP_006319 (OMIM: 612409) RNA-binding protein 14 is ( 669) 498 75.0 5.3e-13
NP_001185765 (OMIM: 612409) RNA-binding protein 14 ( 156) 437 66.4 5.1e-11
NP_001185766 (OMIM: 612409) RNA-binding protein 14 ( 119) 305 49.9 3.4e-06
>>NP_002887 (OMIM: 602571) RNA-binding protein 4 isoform (364 aa)
initn: 1922 init1: 1466 opt: 2134 Z-score: 1440.9 bits: 275.2 E(85289): 1.6e-73
Smith-Waterman score: 2134; 89.3% identity (97.0% similar) in 365 aa overlap (1-359:1-364)
10 20 30 40 50 60
pF1KB8 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMER
:::::::::::::::.:::::::::::::::.::::::::::::::::::::::::::::
NP_002 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::.
NP_002 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRS
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 GRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGALD-YYKRYRV-RSYEAVAAAAAA
:::::.:::::::::::::::::.::.:.:::.:::::: :::: :. :::::::::::
NP_002 GRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGALDAYYKRCRAARSYEAVAAAAA-
190 200 210 220 230
240 250 260 270 280 290
pF1KB8 SAYNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYDRHLLPNSGAAATSAAMAAAAAT----
:.:::::::.:.:::::.:...:::.:::.:::::::::.::::::.:: :::::.
NP_002 SVYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 TSSYYGRDRSPLRRAAAMLPTVGEGYGYGPESELSQASAATRNSLYDMARYEREQYVDRA
..:::::::::::::.: .:::::::::: ::::::::::.:::::::::::::::.:::
NP_002 STSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNSLYDMARYEREQYADRA
300 310 320 330 340 350
pF1KB8 RYSAF
:::::
NP_002 RYSAF
360
>>NP_001185773 (OMIM: 602571) RNA-binding protein 4 isof (173 aa)
initn: 921 init1: 902 opt: 902 Z-score: 626.8 bits: 123.5 E(85289): 3.6e-28
Smith-Waterman score: 902; 98.6% identity (100.0% similar) in 139 aa overlap (1-139:1-139)
10 20 30 40 50 60
pF1KB8 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMER
:::::::::::::::.:::::::::::::::.::::::::::::::::::::::::::::
NP_001 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRT
:::::::::::::::::::
NP_001 AEDAVEAIRGLDNTEFQGKITPVTEGYCCCNKGHTYIFKNCNLILESRKSRRC
130 140 150 160 170
>>NP_001185772 (OMIM: 602571) RNA-binding protein 4 isof (143 aa)
initn: 896 init1: 896 opt: 896 Z-score: 623.4 bits: 122.6 E(85289): 5.5e-28
Smith-Waterman score: 896; 98.6% identity (100.0% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KB8 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMER
:::::::::::::::.:::::::::::::::.::::::::::::::::::::::::::::
NP_001 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRT
::::::::::::::::::
NP_001 AEDAVEAIRGLDNTEFQGGMCVG
130 140
>>NP_006319 (OMIM: 612409) RNA-binding protein 14 isofor (669 aa)
initn: 480 init1: 326 opt: 498 Z-score: 354.3 bits: 75.0 E(85289): 5.3e-13
Smith-Waterman score: 510; 33.0% identity (60.1% similar) in 358 aa overlap (2-334:1-355)
10 20 30 40 50
pF1KB8 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK
.:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: ..
NP_006 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LH-GVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHM
:. : . :: :. . . :. :::.: .::.::::. ::. : :::::.:::::::::
NP_006 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 ERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVD
:. :: :: :.. : .:::..:.:::. . .::.. ::: . : : . :
NP_006 EKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSG-DKTKKPGAGDTAFP-G
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 RTGRVA--DFTEQYNEQYGAVR------TPYTMGYGESMYYND----AYGALDYYKRYRV
: : :. . .... :. :: .: .: . .: : .
NP_006 TGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 RSYEAVAAAAAASAYNYAEQTMSHLPQVQSTTVTSHLNSTSVD---PYDRHLL-PNSGAA
:. .:. .:: : : ... : ... ..:. . ::. :: .: :.: .:
NP_006 RAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSA
240 250 260 270 280 290
290 300 310 320 330
pF1KB8 ATSA-----AMAAAAATTSSYYGRDR--SPLRRAAAMLPTVGEGYGYGPESELSQASAAT
:.:. . .:.. ::: :. : : .:. ... .:: : : .::...
NP_006 AASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLA-SYGNQPSSYGAQAASSY
300 310 320 330 340 350
340 350
pF1KB8 RNSLYDMARYEREQYVDRARYSAF
NP_006 GVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAP
360 370 380 390 400 410
>>NP_001185765 (OMIM: 612409) RNA-binding protein 14 iso (156 aa)
initn: 395 init1: 292 opt: 437 Z-score: 318.8 bits: 66.4 E(85289): 5.1e-11
Smith-Waterman score: 437; 45.9% identity (75.0% similar) in 148 aa overlap (2-147:1-148)
10 20 30 40 50
pF1KB8 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK
.:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: ..
NP_001 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LH-GVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHM
:. : . :: :. . . :. :::.: .::.::::. ::. : :::::.:::::::::
NP_001 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 ERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVD
:. :: :: :.. : .:::..:.:::
NP_001 EKEADAKAAIAQLNGKEVKGKRINVELSTKGMVPTGV
120 130 140 150
>>NP_001185766 (OMIM: 612409) RNA-binding protein 14 iso (119 aa)
initn: 263 init1: 160 opt: 305 Z-score: 232.3 bits: 49.9 E(85289): 3.4e-06
Smith-Waterman score: 305; 42.0% identity (74.1% similar) in 112 aa overlap (2-111:1-112)
10 20 30 40 50
pF1KB8 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK
.:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: ..
NP_001 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LH-GVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHM
:. : . :: :. . . :. :::.: .::.::::. ::. : :::::.::
NP_001 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKGMVPTGV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 ERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVD
359 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:08:03 2016 done: Fri Nov 4 10:08:04 2016
Total Scan time: 5.850 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]