Result of FASTA (omim) for
pFN21AB8107
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8107, 222 aa
1>>>pF1KB8107 222 - 222 aa - 222 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5907+/-0.000301; mu= 9.8692+/- 0.019
mean_var=112.9227+/-23.049, 0's: 0 Z-trim(119.9): 19 B-trim: 2587 in 2/55
Lambda= 0.120693
statistics sampled from 34550 (34569) to 34550 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.405), width: 16
Scan time: 6.030
The best scores are: opt bits E(85289)
NP_057163 (OMIM: 610052) charged multivesicular bo ( 222) 1385 251.0 1.2e-66
NP_001005753 (OMIM: 610052) charged multivesicular ( 156) 957 176.3 2.4e-44
NP_001180446 (OMIM: 610052) charged multivesicular ( 182) 688 129.5 3.5e-30
NP_054762 (OMIM: 600795,609512,614696) charged mul ( 213) 311 63.9 2.3e-10
NP_940818 (OMIM: 610893) charged multivesicular bo ( 222) 308 63.4 3.4e-10
NP_055268 (OMIM: 610893) charged multivesicular bo ( 222) 308 63.4 3.4e-10
XP_011531878 (OMIM: 600795,609512,614696) PREDICTE ( 229) 307 63.3 3.9e-10
XP_005258804 (OMIM: 610893) PREDICTED: charged mul ( 265) 305 63.0 5.6e-10
XP_005258803 (OMIM: 610893) PREDICTED: charged mul ( 265) 305 63.0 5.6e-10
NP_001231573 (OMIM: 600795,609512,614696) charged ( 172) 268 56.4 3.4e-08
>>NP_057163 (OMIM: 610052) charged multivesicular body p (222 aa)
initn: 1385 init1: 1385 opt: 1385 Z-score: 1317.6 bits: 251.0 E(85289): 1.2e-66
Smith-Waterman score: 1385; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA
130 140 150 160 170 180
190 200 210 220
pF1KB8 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
::::::::::::::::::::::::::::::::::::::::::
NP_057 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
190 200 210 220
>>NP_001005753 (OMIM: 610052) charged multivesicular bod (156 aa)
initn: 957 init1: 957 opt: 957 Z-score: 917.0 bits: 176.3 E(85289): 2.4e-44
Smith-Waterman score: 957; 100.0% identity (100.0% similar) in 156 aa overlap (67-222:1-156)
40 50 60 70 80 90
pF1KB8 IQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLA
::::::::::::::::::::::::::::::
NP_001 MIRSRKAVSKLYASKAHMNSVLMGMKNQLA
10 20 30
100 110 120 130 140 150
pF1KB8 VLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB8 MEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSR
100 110 120 130 140 150
220
pF1KB8 LATLRS
::::::
NP_001 LATLRS
>>NP_001180446 (OMIM: 610052) charged multivesicular bod (182 aa)
initn: 688 init1: 688 opt: 688 Z-score: 662.9 bits: 129.5 E(85289): 3.5e-30
Smith-Waterman score: 1057; 82.0% identity (82.0% similar) in 222 aa overlap (1-222:1-182)
10 20 30 40 50 60
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI
::::::::::: :::::::::
NP_001 IVLAKEMIRSR----------------------------------------KAMQSLVKI
70 80
130 140 150 160 170 180
pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA
90 100 110 120 130 140
190 200 210 220
pF1KB8 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
::::::::::::::::::::::::::::::::::::::::::
NP_001 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
150 160 170 180
>>NP_054762 (OMIM: 600795,609512,614696) charged multive (213 aa)
initn: 315 init1: 241 opt: 311 Z-score: 307.2 bits: 63.9 E(85289): 2.3e-10
Smith-Waterman score: 311; 27.5% identity (69.1% similar) in 207 aa overlap (8-210:6-210)
10 20 30 40 50 60
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
..: ....: . ..: .:.. :. ....:.... .: :: :.:..:
NP_054 MASLFKKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEAC
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI
::::.... :: .. .: .....:. : . . ...::... ....:.:... .
NP_054 KVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDP
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDT----FESMDDQEEMEEEAEMEIDRILFEITAGA
. ::....:: :: . :::..:: :.. ::.:: .. ... .:.: .::. :
NP_054 QKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEIS-GK
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 LGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
..:::: .. .:: : ..:. :.. .::
NP_054 MAKAPS-AARSLPSASTSKATISDEEIERQLKALGVD
180 190 200 210
>>NP_940818 (OMIM: 610893) charged multivesicular body p (222 aa)
initn: 288 init1: 288 opt: 308 Z-score: 304.1 bits: 63.4 E(85289): 3.4e-10
Smith-Waterman score: 308; 27.4% identity (63.0% similar) in 219 aa overlap (3-220:4-212)
10 20 30 40 50
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV
:::. .: :.::. . . . . :: .::. . .. .:.:. ..: ::.:: :.
NP_940 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK
..::...:.:. : :. .:....: . ... . .: ... :..: .:. .:
NP_940 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK
.:.:: : :. .. . :::..:.... .:: :::.. ....: : ::
NP_940 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDE-----LGL
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 APSKVTDALPE-PEPPGAMAASEDEEEEEEALEAMQSRLATLRS
. .:: : . : :..... .. : : :. . : :
NP_940 S---LTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
180 190 200 210 220
>>NP_055268 (OMIM: 610893) charged multivesicular body p (222 aa)
initn: 288 init1: 288 opt: 308 Z-score: 304.1 bits: 63.4 E(85289): 3.4e-10
Smith-Waterman score: 308; 27.4% identity (63.0% similar) in 219 aa overlap (3-220:4-212)
10 20 30 40 50
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV
:::. .: :.::. . . . . :: .::. . .. .:.:. ..: ::.:: :.
NP_055 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK
..::...:.:. : :. .:....: . ... . .: ... :..: .:. .:
NP_055 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK
.:.:: : :. .. . :::..:.... .:: :::.. ....: : ::
NP_055 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDE-----LGL
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 APSKVTDALPE-PEPPGAMAASEDEEEEEEALEAMQSRLATLRS
. .:: : . : :..... .. : : :. . : :
NP_055 S---LTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
180 190 200 210 220
>>XP_011531878 (OMIM: 600795,609512,614696) PREDICTED: c (229 aa)
initn: 315 init1: 241 opt: 307 Z-score: 303.0 bits: 63.3 E(85289): 3.9e-10
Smith-Waterman score: 307; 27.9% identity (69.2% similar) in 201 aa overlap (14-210:28-226)
10 20 30 40
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKR
....: . ..: .:.. :. ....:....
XP_011 MISAQRNHHLPDSSDSSTSAYRVARITDVIKEQNRELRGTQRAIIRDRAALEKQEKQLEL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 SVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQK
.: :: :.:..: ::::.... :: .. .: .....:. : . . ...::...
XP_011 EIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMST
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 STEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDT----FESMDDQEEMEEEAE
....:.:... . . ::....:: :: . :::..:: :.. ::.:: .. ..
XP_011 TAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 MEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
. .:.: .::. : ..:::: . .:: : ..:. :.. .::
XP_011 QVLDEIGIEIS-GKMAKAPSAAR-SLPSASTSKATISDEEIERQLKALGVD
190 200 210 220
>>XP_005258804 (OMIM: 610893) PREDICTED: charged multive (265 aa)
initn: 358 init1: 268 opt: 305 Z-score: 300.2 bits: 63.0 E(85289): 5.6e-10
Smith-Waterman score: 305; 27.1% identity (63.3% similar) in 199 aa overlap (3-200:4-200)
10 20 30 40 50
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV
:::. .: :.::. . . . . :: .::. . .. .:.:. ..: ::.:: :.
XP_005 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK
..::...:.:. : :. .:....: . ... . .: ... :..: .:. .:
XP_005 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK
.:.:: : :. .. . :::..:.... .:: :::.. ....: :. . .
XP_005 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDE
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 APSKVTDA-LPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
:. . . : : : : :
XP_005 LSSECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGG
180 190 200 210 220 230
>>XP_005258803 (OMIM: 610893) PREDICTED: charged multive (265 aa)
initn: 358 init1: 268 opt: 305 Z-score: 300.2 bits: 63.0 E(85289): 5.6e-10
Smith-Waterman score: 305; 27.1% identity (63.3% similar) in 199 aa overlap (3-200:4-200)
10 20 30 40 50
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV
:::. .: :.::. . . . . :: .::. . .. .:.:. ..: ::.:: :.
XP_005 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK
..::...:.:. : :. .:....: . ... . .: ... :..: .:. .:
XP_005 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK
.:.:: : :. .. . :::..:.... .:: :::.. ....: :. . .
XP_005 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDE
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 APSKVTDA-LPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
:. . . : : : : :
XP_005 LSSECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGG
180 190 200 210 220 230
>>NP_001231573 (OMIM: 600795,609512,614696) charged mult (172 aa)
initn: 315 init1: 241 opt: 268 Z-score: 268.0 bits: 56.4 E(85289): 3.4e-08
Smith-Waterman score: 268; 30.5% identity (69.5% similar) in 167 aa overlap (48-210:5-169)
20 30 40 50 60 70
pF1KB8 EWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKL
.: :: :.:..: ::::.... :: ..
NP_001 MELEIKKMAKIGNKEACKVLAKQLVHLRKQKTRT
10 20 30
80 90 100 110 120 130
pF1KB8 YASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKA
.: .....:. : . . ...::... ....:.:... . . ::....:: ::
NP_001 FAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKM
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 GIIEEMLEDT----FESMDDQEEMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEP
. :::..:: :.. ::.:: .. ... .:.: .::. : ..:::: .. .::
NP_001 EMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEIS-GKMAKAPS-AARSLPSAST
100 110 120 130 140 150
200 210 220
pF1KB8 PGAMAASEDEEEEEEALEAMQSRLATLRS
: ..:. :.. .::
NP_001 SKATISDEEIERQLKALGVD
160 170
222 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:33:09 2016 done: Fri Nov 4 09:33:10 2016
Total Scan time: 6.030 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]