Result of FASTA (omim) for
pFN21AB7719
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7719, 427 aa
1>>>pF1KB7719 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3301+/-0.000321; mu= 13.0545+/- 0.020
mean_var=92.0653+/-18.834, 0's: 0 Z-trim(117.8): 411 B-trim: 91 in 1/53
Lambda= 0.133668
statistics sampled from 29728 (30146) to 29728 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.353), width: 16
Scan time: 8.460
The best scores are: opt bits E(85289)
XP_011537022 (OMIM: 166710,277440,601769) PREDICTE ( 427) 2897 568.6 1.1e-161
NP_001017535 (OMIM: 166710,277440,601769) vitamin ( 427) 2897 568.6 1.1e-161
NP_000367 (OMIM: 166710,277440,601769) vitamin D3 ( 427) 2897 568.6 1.1e-161
XP_006719650 (OMIM: 166710,277440,601769) PREDICTE ( 427) 2897 568.6 1.1e-161
NP_001017536 (OMIM: 166710,277440,601769) vitamin ( 477) 2897 568.6 1.2e-161
NP_003880 (OMIM: 603065) nuclear receptor subfamil ( 434) 965 196.0 1.6e-49
NP_071285 (OMIM: 603065) nuclear receptor subfamil ( 473) 965 196.0 1.7e-49
NP_148934 (OMIM: 603065) nuclear receptor subfamil ( 397) 534 112.9 1.5e-24
NP_001070942 (OMIM: 603881) nuclear receptor subfa ( 296) 479 102.2 1.9e-21
NP_001070939 (OMIM: 603881) nuclear receptor subfa ( 309) 479 102.2 1.9e-21
NP_001070949 (OMIM: 603881) nuclear receptor subfa ( 314) 479 102.2 2e-21
NP_001070946 (OMIM: 603881) nuclear receptor subfa ( 339) 479 102.2 2.1e-21
NP_001070937 (OMIM: 603881) nuclear receptor subfa ( 340) 479 102.2 2.1e-21
NP_005113 (OMIM: 603881) nuclear receptor subfamil ( 348) 479 102.2 2.1e-21
NP_001070948 (OMIM: 603881) nuclear receptor subfa ( 352) 479 102.2 2.2e-21
XP_005245754 (OMIM: 603881) PREDICTED: nuclear rec ( 353) 479 102.2 2.2e-21
NP_001070950 (OMIM: 603881) nuclear receptor subfa ( 357) 479 102.2 2.2e-21
XP_005252773 (OMIM: 602423) PREDICTED: oxysterols ( 313) 449 96.4 1.1e-19
XP_011518109 (OMIM: 602423) PREDICTED: oxysterols ( 313) 449 96.4 1.1e-19
XP_011518110 (OMIM: 602423) PREDICTED: oxysterols ( 235) 447 96.0 1.1e-19
XP_005252772 (OMIM: 602423) PREDICTED: oxysterols ( 358) 449 96.4 1.2e-19
NP_001070947 (OMIM: 603881) nuclear receptor subfa ( 319) 437 94.1 5.5e-19
NP_001243576 (OMIM: 600380) oxysterols receptor LX ( 364) 426 92.0 2.7e-18
XP_005245751 (OMIM: 603881) PREDICTED: nuclear rec ( 424) 419 90.7 7.7e-18
XP_016872546 (OMIM: 602423) PREDICTED: oxysterols ( 323) 385 84.1 5.8e-16
XP_016872545 (OMIM: 602423) PREDICTED: oxysterols ( 332) 385 84.1 5.9e-16
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols ( 402) 385 84.1 6.9e-16
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402) 385 84.1 6.9e-16
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols ( 402) 385 84.1 6.9e-16
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols ( 402) 385 84.1 6.9e-16
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols ( 402) 385 84.1 6.9e-16
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols ( 402) 385 84.1 6.9e-16
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols ( 447) 385 84.2 7.6e-16
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols ( 447) 385 84.2 7.6e-16
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols ( 447) 385 84.2 7.6e-16
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols ( 447) 385 84.2 7.6e-16
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols ( 447) 385 84.2 7.6e-16
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols ( 447) 385 84.2 7.6e-16
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447) 385 84.2 7.6e-16
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453) 385 84.2 7.7e-16
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453) 385 84.2 7.7e-16
XP_011518108 (OMIM: 602423) PREDICTED: oxysterols ( 342) 381 83.3 1e-15
XP_005252770 (OMIM: 602423) PREDICTED: oxysterols ( 387) 381 83.3 1.1e-15
NP_001123573 (OMIM: 602423) oxysterols receptor LX ( 387) 381 83.3 1.1e-15
XP_011532355 (OMIM: 145650,188570,190160,274300) P ( 430) 375 82.2 2.8e-15
XP_016862602 (OMIM: 145650,188570,190160,274300) P ( 430) 375 82.2 2.8e-15
XP_016862603 (OMIM: 145650,188570,190160,274300) P ( 430) 375 82.2 2.8e-15
XP_016862604 (OMIM: 145650,188570,190160,274300) P ( 430) 375 82.2 2.8e-15
XP_005265480 (OMIM: 145650,188570,190160,274300) P ( 461) 375 82.2 3e-15
XP_016862598 (OMIM: 145650,188570,190160,274300) P ( 461) 375 82.2 3e-15
>>XP_011537022 (OMIM: 166710,277440,601769) PREDICTED: v (427 aa)
initn: 2897 init1: 2897 opt: 2897 Z-score: 3023.8 bits: 568.6 E(85289): 1.1e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
370 380 390 400 410 420
pF1KB7 VFGNEIS
:::::::
XP_011 VFGNEIS
>>NP_001017535 (OMIM: 166710,277440,601769) vitamin D3 r (427 aa)
initn: 2897 init1: 2897 opt: 2897 Z-score: 3023.8 bits: 568.6 E(85289): 1.1e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
370 380 390 400 410 420
pF1KB7 VFGNEIS
:::::::
NP_001 VFGNEIS
>>NP_000367 (OMIM: 166710,277440,601769) vitamin D3 rece (427 aa)
initn: 2897 init1: 2897 opt: 2897 Z-score: 3023.8 bits: 568.6 E(85289): 1.1e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
370 380 390 400 410 420
pF1KB7 VFGNEIS
:::::::
NP_000 VFGNEIS
>>XP_006719650 (OMIM: 166710,277440,601769) PREDICTED: v (427 aa)
initn: 2897 init1: 2897 opt: 2897 Z-score: 3023.8 bits: 568.6 E(85289): 1.1e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
370 380 390 400 410 420
pF1KB7 VFGNEIS
:::::::
XP_006 VFGNEIS
>>NP_001017536 (OMIM: 166710,277440,601769) vitamin D3 r (477 aa)
initn: 2897 init1: 2897 opt: 2897 Z-score: 3023.1 bits: 568.6 E(85289): 1.2e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:51-477)
10 20 30
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDR
::::::::::::::::::::::::::::::
NP_001 VEEAFGSEVSVRPHRRAPLGSTYLPPAPSGMEAMAASTSLPDPGDFDRNVPRICGVCGDR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB7 ATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMM
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB7 KEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDF
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB7 CQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEE
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB7 DSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEV
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB7 IMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEH
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB7 VLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADL
390 400 410 420 430 440
400 410 420
pF1KB7 RSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS
:::::::::::::::::::::::::::::::::::::
NP_001 RSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS
450 460 470
>>NP_003880 (OMIM: 603065) nuclear receptor subfamily 1 (434 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1010.2 bits: 196.0 E(85289): 1.6e-49
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (21-423:38-430)
10 20 30 40 50
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
NP_003 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
10 20 30 40 50 60
60 70 80 90 100
pF1KB7 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_003 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
NP_003 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
NP_003 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
190 200 210 220 230
230 240 250 260 270 280
pF1KB7 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
NP_003 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
NP_003 ECGR--LSYCLED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB7 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
NP_003 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
360 370 380 390 400 410
410 420
pF1KB7 FQPECSMKLTPLVLEVFGNEIS
..: :::. :.::
NP_003 IHPFA----TPLMQELFGITGS
420 430
>>NP_071285 (OMIM: 603065) nuclear receptor subfamily 1 (473 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1009.6 bits: 196.0 E(85289): 1.7e-49
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (21-423:77-469)
10 20 30 40 50
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
NP_071 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
50 60 70 80 90 100
60 70 80 90 100
pF1KB7 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_071 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
110 120 130 140 150 160
110 120 130 140 150 160
pF1KB7 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
NP_071 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
170 180 190 200 210 220
170 180 190 200 210 220
pF1KB7 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
NP_071 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
230 240 250 260 270
230 240 250 260 270 280
pF1KB7 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
NP_071 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
280 290 300 310 320 330
290 300 310 320 330 340
pF1KB7 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
NP_071 ECGR--LSYCLED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
340 350 360 370 380 390
350 360 370 380 390 400
pF1KB7 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
NP_071 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
400 410 420 430 440 450
410 420
pF1KB7 FQPECSMKLTPLVLEVFGNEIS
..: :::. :.::
NP_071 IHPFA----TPLMQELFGITGS
460 470
>>NP_148934 (OMIM: 603065) nuclear receptor subfamily 1 (397 aa)
initn: 882 init1: 297 opt: 534 Z-score: 561.6 bits: 112.9 E(85289): 1.5e-24
Smith-Waterman score: 976; 40.8% identity (67.1% similar) in 407 aa overlap (21-423:38-393)
10 20 30 40 50
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
NP_148 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
10 20 30 40 50 60
60 70 80 90 100
pF1KB7 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_148 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: ... :: .
NP_148 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSVWN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 -RPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSML
.: :. :: . :. .:.:
NP_148 YKP-----PADSGGK-------------------------------------EI--FSLL
190 200
230 240 250 260 270 280
pF1KB7 PHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWT
::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
NP_148 PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWE
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB7 CGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQ
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
NP_148 CGR--LSYCLED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVL
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB7 DAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLSF
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : ..
NP_148 QHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDI
330 340 350 360 370 380
410 420
pF1KB7 QPECSMKLTPLVLEVFGNEIS
.: :::. :.::
NP_148 HPFA----TPLMQELFGITGS
390
>>NP_001070942 (OMIM: 603881) nuclear receptor subfamily (296 aa)
initn: 713 init1: 398 opt: 479 Z-score: 506.2 bits: 102.2 E(85289): 1.9e-21
Smith-Waterman score: 542; 34.4% identity (57.7% similar) in 279 aa overlap (22-299:9-228)
10 20 30 40 50 60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
: : ::::.:::.::::.:::::::::::..... ::
NP_001 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTC
10 20 30 40
70 80 90 100 110 120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
:: :.:...: .:::: ::::..:.: :: :..::. : . .: .:. ...
NP_001 PFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQT-----
50 60 70 80 90 100
130 140 150 160 170
pF1KB7 RP-KLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFS
: .::.::...: :: :: . . . .: :::::... : : :
NP_001 -PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLF----IH-------HQPL--
110 120 130 140
180 190 200 210 220 230
pF1KB7 GDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQ
:... : .. :.::. .. .
NP_001 -----------------------------------PTLA---PVLPLVTHFADINTFMVL
150 160 170
240 250 260 270 280 290
pF1KB7 KVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSD
.:: :.: .: ::.: :::: :::..:.:. . : .: .. ... :: .: . :
NP_001 QVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCG--PLRYTIED
180 190 200 210 220
300 310 320 330 340 350
pF1KB7 VTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRL
NP_001 GARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPG
230 240 250 260 270 280
>>NP_001070939 (OMIM: 603881) nuclear receptor subfamily (309 aa)
initn: 788 init1: 398 opt: 479 Z-score: 505.9 bits: 102.2 E(85289): 1.9e-21
Smith-Waterman score: 613; 31.4% identity (54.4% similar) in 401 aa overlap (22-421:9-307)
10 20 30 40 50 60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
: : ::::.:::.::::.:::::::::::..... ::
NP_001 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTC
10 20 30 40
70 80 90 100 110 120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
:: :.:...: .:::: ::::..:.: :: :..::. : . .: .:. ...
NP_001 PFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQT-----
50 60 70 80 90 100
130 140 150 160 170
pF1KB7 RP-KLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFS
: .::.::...: :: :: . . . .: :::::... .: :
NP_001 -PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLF-----------IHHQPL--
110 120 130 140
180 190 200 210 220 230
pF1KB7 GDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQ
:... : .. :.::. .. .
NP_001 -----------------------------------PTLA---PVLPLVTHFADINTFMVL
150 160 170
240 250 260 270 280 290
pF1KB7 KVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSD
.:: :.: .: ::.: :::: :::..:.:. . : .: .. ... :: .: . :
NP_001 QVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCG--PLRYTIED
180 190 200 210 220
300 310 320 330 340 350
pF1KB7 VTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRL
: . ::::: . :. .:...
NP_001 -------------------GAR--------------------DRPGVTQRDEIDQLQEEM
230 240
360 370 380 390 400 410
pF1KB7 SNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVL
. :::.::. .. : ...::::.. ::.:::.:: .. : . .: .: ::.
NP_001 ALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ--HIQGLSAM--MPLLQ
250 260 270 280 290 300
420
pF1KB7 EVFGNEIS
:.
NP_001 EICS
427 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:15:22 2016 done: Fri Nov 4 09:15:24 2016
Total Scan time: 8.460 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]