Result of FASTA (omim) for
pFN21AB7663
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7663, 336 aa
1>>>pF1KB7663 336 - 336 aa - 336 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4854+/-0.000519; mu= 12.4540+/- 0.032
mean_var=181.6238+/-39.508, 0's: 0 Z-trim(114.5): 138 B-trim: 1876 in 2/48
Lambda= 0.095167
statistics sampled from 24172 (24329) to 24172 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.285), width: 16
Scan time: 8.060
The best scores are: opt bits E(85289)
XP_011508153 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 336) 2206 315.4 1.1e-85
XP_011508154 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 336) 2206 315.4 1.1e-85
NP_009143 (OMIM: 608985) E3 ubiquitin-protein liga ( 336) 2206 315.4 1.1e-85
XP_005245470 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 287) 1895 272.6 7e-73
NP_002922 (OMIM: 602045) E3 ubiquitin-protein liga ( 406) 882 133.7 6.4e-31
>>XP_011508153 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr (336 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 1659.4 bits: 315.4 E(85289): 1.1e-85
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KB7 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
250 260 270 280 290 300
310 320 330
pF1KB7 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
::::::::::::::::::::::::::::::::::::
XP_011 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
310 320 330
>>XP_011508154 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr (336 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 1659.4 bits: 315.4 E(85289): 1.1e-85
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KB7 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
250 260 270 280 290 300
310 320 330
pF1KB7 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
::::::::::::::::::::::::::::::::::::
XP_011 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
310 320 330
>>NP_009143 (OMIM: 608985) E3 ubiquitin-protein ligase R (336 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 1659.4 bits: 315.4 E(85289): 1.1e-85
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KB7 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
250 260 270 280 290 300
310 320 330
pF1KB7 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
::::::::::::::::::::::::::::::::::::
NP_009 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
310 320 330
>>XP_005245470 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr (287 aa)
initn: 1895 init1: 1895 opt: 1895 Z-score: 1429.4 bits: 272.6 E(85289): 7e-73
Smith-Waterman score: 1895; 100.0% identity (100.0% similar) in 287 aa overlap (50-336:1-287)
20 30 40 50 60 70
pF1KB7 SLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITA
::::::::::::::::::::::::::::::
XP_005 MCPICLDMLKNTMTTKECLHRFCADCIITA
10 20 30
80 90 100 110 120 130
pF1KB7 LRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 LSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKT
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB7 SDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB7 SKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYW
220 230 240 250 260 270
320 330
pF1KB7 KVNKPMELYYAPTKEHK
:::::::::::::::::
XP_005 KVNKPMELYYAPTKEHK
280
>>NP_002922 (OMIM: 602045) E3 ubiquitin-protein ligase R (406 aa)
initn: 1379 init1: 872 opt: 882 Z-score: 676.1 bits: 133.7 E(85289): 6.4e-31
Smith-Waterman score: 1083; 59.7% identity (73.9% similar) in 310 aa overlap (11-280:8-315)
10 20 30 40 50 60
pF1KB7 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
: :::::::::::.::::::: :: ::.:::::::::::::::::::::
NP_002 MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKN
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::.::
NP_002 TMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEY
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQR------GKKQQ--IENGSG--A
::::.::: :... .:::::: ::::::..:::.: :: :. : . .: : .
NP_002 EAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPG
120 130 140 150 160 170
180 190 200
pF1KB7 EDNGDSSHCSNASTHSNQEAGPSNKRTKT-----------------------SDDSGLEL
: .::. :. :. .. ::. :: . :.::: .
NP_002 EGEGDGEDVSSDSA-PDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRG
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 DNNNAAMAIDPVMDGA-------SEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLS
. ... : :: .:::::::::: :.:: . ::::.::.:::::::::
NP_002 GTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLS
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB7 KYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWK
::::.:.:::. :.. :...
NP_002 KYLALRIALER-RQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEG
300 310 320 330 340 350
>--
initn: 298 init1: 236 opt: 242 Z-score: 201.2 bits: 45.9 E(85289): 0.00018
Smith-Waterman score: 242; 65.5% identity (90.9% similar) in 55 aa overlap (282-336:352-406)
260 270 280 290 300 310
pF1KB7 GNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSL
.:. .:::::::::: ..: ::.::::..:
NP_002 GASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTL
330 340 350 360 370 380
320 330
pF1KB7 ELVSEKYWKVNKPMELYYAPTKEHK
:::.::.:::..:.:: :::::. :
NP_002 ELVNEKFWKVSRPLELCYAPTKDPK
390 400
336 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:09:20 2016 done: Fri Nov 4 09:09:21 2016
Total Scan time: 8.060 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]