Result of FASTA (omim) for
pFN21AB7261
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7261, 196 aa
1>>>pF1KB7261 196 - 196 aa - 196 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1260+/-0.000299; mu= 14.8828+/- 0.019
mean_var=72.6176+/-14.535, 0's: 0 Z-trim(117.2): 46 B-trim: 0 in 0/55
Lambda= 0.150506
statistics sampled from 28916 (28962) to 28916 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.34), width: 16
Scan time: 6.320
The best scores are: opt bits E(85289)
NP_148983 (OMIM: 173430) platelet-derived growth f ( 196) 1313 293.6 1.3e-79
XP_011513720 (OMIM: 173430) PREDICTED: platelet-de ( 234) 1313 293.7 1.5e-79
NP_002598 (OMIM: 173430) platelet-derived growth f ( 211) 1293 289.3 2.9e-78
XP_011513718 (OMIM: 173430) PREDICTED: platelet-de ( 249) 1293 289.3 3.3e-78
XP_016867778 (OMIM: 173430) PREDICTED: platelet-de ( 224) 1159 260.2 1.7e-69
XP_011513721 (OMIM: 173430) PREDICTED: platelet-de ( 210) 1153 258.9 4.1e-69
XP_011513719 (OMIM: 173430) PREDICTED: platelet-de ( 241) 975 220.3 2e-57
XP_011513717 (OMIM: 173430) PREDICTED: platelet-de ( 256) 955 216.0 4.2e-56
NP_002599 (OMIM: 190040,213600,607174,607907,61548 ( 241) 500 117.1 2.2e-26
NP_148937 (OMIM: 190040,213600,607174,607907,61548 ( 226) 471 110.8 1.6e-24
NP_001230662 (OMIM: 601398) vascular endothelial g ( 188) 182 48.0 1.1e-05
NP_003368 (OMIM: 601398) vascular endothelial grow ( 207) 182 48.1 1.2e-05
NP_004460 (OMIM: 300091) vascular endothelial grow ( 354) 163 44.1 0.00031
NP_001280572 (OMIM: 601121) placenta growth factor ( 169) 153 41.7 0.0008
NP_002623 (OMIM: 601121) placenta growth factor is ( 170) 153 41.7 0.0008
NP_001193941 (OMIM: 601121) placenta growth factor ( 149) 150 41.0 0.0011
NP_005420 (OMIM: 601528,615907) vascular endotheli ( 419) 154 42.2 0.0014
XP_016863944 (OMIM: 608452) PREDICTED: platelet-de ( 310) 149 41.0 0.0023
XP_011530426 (OMIM: 608452) PREDICTED: platelet-de ( 334) 149 41.0 0.0025
NP_057289 (OMIM: 608452) platelet-derived growth f ( 345) 149 41.1 0.0025
NP_001165101 (OMIM: 192240,603933) vascular endoth ( 137) 139 38.6 0.0056
NP_001191313 (OMIM: 192240,603933) vascular endoth ( 171) 138 38.4 0.0077
NP_001165096 (OMIM: 192240,603933) vascular endoth ( 209) 138 38.5 0.009
NP_001165095 (OMIM: 192240,603933) vascular endoth ( 215) 138 38.5 0.0092
NP_001165099 (OMIM: 192240,603933) vascular endoth ( 147) 136 37.9 0.0093
NP_001165094 (OMIM: 192240,603933) vascular endoth ( 232) 138 38.5 0.0097
>>NP_148983 (OMIM: 173430) platelet-derived growth facto (196 aa)
initn: 1313 init1: 1313 opt: 1313 Z-score: 1550.0 bits: 293.6 E(85289): 1.3e-79
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
130 140 150 160 170 180
190
pF1KB7 TTSLNPDYREEDTDVR
::::::::::::::::
NP_148 TTSLNPDYREEDTDVR
190
>>XP_011513720 (OMIM: 173430) PREDICTED: platelet-derive (234 aa)
initn: 1313 init1: 1313 opt: 1313 Z-score: 1548.9 bits: 293.7 E(85289): 1.5e-79
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:39-234)
10 20 30
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVI
::::::::::::::::::::::::::::::
XP_011 RGRVAAARRPAGAPAPRPRLSSEQPAPRDAMRTLACLLLLGCGYLAHVLAEEAEIPREVI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 ERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB7 AVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSV
130 140 150 160 170 180
160 170 180 190
pF1KB7 KVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
190 200 210 220 230
>>NP_002598 (OMIM: 173430) platelet-derived growth facto (211 aa)
initn: 1293 init1: 1293 opt: 1293 Z-score: 1526.1 bits: 289.3 E(85289): 2.9e-78
Smith-Waterman score: 1293; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
130 140 150 160 170 180
190
pF1KB7 TTSLNPDYREEDTDVR
:::::::::::::
NP_002 TTSLNPDYREEDTGRPRESGKKRKRKRLKPT
190 200 210
>>XP_011513718 (OMIM: 173430) PREDICTED: platelet-derive (249 aa)
initn: 1293 init1: 1293 opt: 1293 Z-score: 1525.1 bits: 289.3 E(85289): 3.3e-78
Smith-Waterman score: 1293; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:39-231)
10 20 30
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVI
::::::::::::::::::::::::::::::
XP_011 RGRVAAARRPAGAPAPRPRLSSEQPAPRDAMRTLACLLLLGCGYLAHVLAEEAEIPREVI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 ERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB7 AVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSV
130 140 150 160 170 180
160 170 180 190
pF1KB7 KVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
:::::::::::::::::::::::::::::::::::::::::::
XP_011 KVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTGRPRESGKKRKRKRLKP
190 200 210 220 230 240
XP_011 T
>>XP_016867778 (OMIM: 173430) PREDICTED: platelet-derive (224 aa)
initn: 1159 init1: 1159 opt: 1159 Z-score: 1368.5 bits: 260.2 E(85289): 1.7e-69
Smith-Waterman score: 1159; 100.0% identity (100.0% similar) in 173 aa overlap (21-193:34-206)
10 20 30 40 50
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEI
::::::::::::::::::::::::::::::
XP_016 HSPRRGNLVLQAPQRPPTLLKNRGGEWGRPEEAEIPREVIERLARSQIHSIRDLQRLLEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 DSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 DPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVR
130 140 150 160 170 180
180 190
pF1KB7 LEEHLECACATTSLNPDYREEDTDVR
:::::::::::::::::::::::
XP_016 LEEHLECACATTSLNPDYREEDTGRPRESGKKRKRKRLKPT
190 200 210 220
>>XP_011513721 (OMIM: 173430) PREDICTED: platelet-derive (210 aa)
initn: 1153 init1: 1153 opt: 1153 Z-score: 1361.8 bits: 258.9 E(85289): 4.1e-69
Smith-Waterman score: 1153; 100.0% identity (100.0% similar) in 172 aa overlap (22-193:21-192)
10 20 30 40 50 60
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
:::::::::::::::::::::::::::::::::::::::
XP_011 MLISLLNQKLSAPSLPPRPSEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
120 130 140 150 160 170
190
pF1KB7 TTSLNPDYREEDTDVR
:::::::::::::
XP_011 TTSLNPDYREEDTGRPRESGKKRKRKRLKPT
180 190 200 210
>>XP_011513719 (OMIM: 173430) PREDICTED: platelet-derive (241 aa)
initn: 975 init1: 975 opt: 975 Z-score: 1152.1 bits: 220.3 E(85289): 2e-57
Smith-Waterman score: 975; 97.9% identity (98.6% similar) in 146 aa overlap (51-196:96-241)
30 40 50 60 70 80
pF1KB7 EEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPL
: . ::::::::::::::::::::::::::
XP_011 GRGSRDPPRGDREAGPQSDPQHPGPPATPGDRLRSEDSLDTSLRAHGVHATKHVPEKRPL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB7 PIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKC
130 140 150 160 170 180
150 160 170 180 190
pF1KB7 QPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
190 200 210 220 230 240
>>XP_011513717 (OMIM: 173430) PREDICTED: platelet-derive (256 aa)
initn: 955 init1: 955 opt: 955 Z-score: 1128.3 bits: 216.0 E(85289): 4.2e-56
Smith-Waterman score: 955; 97.9% identity (98.6% similar) in 143 aa overlap (51-193:96-238)
30 40 50 60 70 80
pF1KB7 EEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPL
: . ::::::::::::::::::::::::::
XP_011 GRGSRDPPRGDREAGPQSDPQHPGPPATPGDRLRSEDSLDTSLRAHGVHATKHVPEKRPL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB7 PIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKC
130 140 150 160 170 180
150 160 170 180 190
pF1KB7 QPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTGRPRESG
190 200 210 220 230 240
XP_011 KKRKRKRLKPT
250
>>NP_002599 (OMIM: 190040,213600,607174,607907,615483) p (241 aa)
initn: 519 init1: 395 opt: 500 Z-score: 594.7 bits: 117.1 E(85289): 2.2e-26
Smith-Waterman score: 500; 46.4% identity (68.3% similar) in 183 aa overlap (7-183:7-184)
10 20 30 40 50
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS--
:.: : :: : :: ::.:. : :. .:.:. ::::::. : : ::.
NP_002 MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDP-GEEDGAE
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 LDTSL-RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTS
:: .. :.:. . . . : : :. : ::. ::::: ..:: : .: :.
NP_002 LDLNMTRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 ANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEH
::::.:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:
NP_002 ANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDH
120 130 140 150 160 170
180 190
pF1KB7 LECACATTSLNPDYREEDTDVR
: : : :..
NP_002 LACKCETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTAL
180 190 200 210 220 230
>>NP_148937 (OMIM: 190040,213600,607174,607907,615483) p (226 aa)
initn: 504 init1: 395 opt: 471 Z-score: 561.1 bits: 110.8 E(85289): 1.6e-24
Smith-Waterman score: 471; 46.7% identity (70.3% similar) in 165 aa overlap (25-183:10-169)
10 20 30 40 50
pF1KB7 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS--
::.:. : :. .:.:. ::::::. : : ::.
NP_148 MFIMGLGDPIPEELYEMLSDHSIRSFDDLQRLLHGDP-GEEDGAE
10 20 30 40
60 70 80 90 100 110
pF1KB7 LDTSL-RAHGVHATKHVPEKRPLPIRRKRSIEEAVPAV---CKTRTVIYEIPRSQVDPTS
:: .. :.:. . . . : : :. : ::. ::::: ..:: : .: :.
NP_148 LDLNMTRSHSGGELESLARGR----RSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTN
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 ANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEH
::::.:::::::.::.::::. .:.:.:..:. : :.: :.: ::::: .:.. : ::.:
NP_148 ANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDH
110 120 130 140 150 160
180 190
pF1KB7 LECACATTSLNPDYREEDTDVR
: : : :..
NP_148 LACKCETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTAL
170 180 190 200 210 220
196 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:26:06 2016 done: Fri Nov 4 06:26:07 2016
Total Scan time: 6.320 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]