Result of FASTA (omim) for
pFN21AB7221
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7221, 207 aa
1>>>pF1KB7221 207 - 207 aa - 207 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0991+/-0.000368; mu= 11.0292+/- 0.023
mean_var=98.7135+/-20.010, 0's: 0 Z-trim(115.3): 20 B-trim: 0 in 0/54
Lambda= 0.129088
statistics sampled from 25584 (25604) to 25584 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.3), width: 16
Scan time: 4.090
The best scores are: opt bits E(85289)
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 1410 272.4 3.6e-73
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 186 44.5 0.00014
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 173 42.0 0.00074
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 170 41.5 0.0011
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 168 41.1 0.0014
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 164 40.4 0.0024
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 163 40.2 0.0027
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 163 40.2 0.0027
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 162 40.0 0.0031
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 162 40.0 0.0031
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 162 40.0 0.0033
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 160 39.6 0.004
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 159 39.4 0.0045
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 159 39.4 0.0045
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 158 39.2 0.0051
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 158 39.2 0.0051
>>NP_064509 (OMIM: 615326) interferon kappa precursor [H (207 aa)
initn: 1410 init1: 1410 opt: 1410 Z-score: 1434.7 bits: 272.4 E(85289): 3.6e-73
Smith-Waterman score: 1410; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207)
10 20 30 40 50 60
pF1KB7 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 QAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSD
130 140 150 160 170 180
190 200
pF1KB7 CAWEIVRVEIRRCLYYFYKFTALFRRK
:::::::::::::::::::::::::::
NP_064 CAWEIVRVEIRRCLYYFYKFTALFRRK
190 200
>>NP_002167 (OMIM: 147640) interferon beta precursor [Ho (187 aa)
initn: 327 init1: 176 opt: 186 Z-score: 203.4 bits: 44.5 E(85289): 0.00014
Smith-Waterman score: 337; 34.0% identity (62.5% similar) in 200 aa overlap (7-205:1-186)
10 20 30 40 50 60
pF1KB7 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
: .::: :. : . .::.. :::. : ..: . : .... . ::
NP_002 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEY-CL
10 20 30 40 50
70 80 90 100 110
pF1KB7 RENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKY-WKERHLKQIQIGLD
.. . :..:.:. : : .:.: ..::: . : :: : . . :.: .... ..
NP_002 KDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 QQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYS
.: ..:. ::: : :.::. . : .:::.:.::. :: ..:: :.::
NP_002 HQINHLKTVLEE-KLEKEDFTRGK------------LMSSLHLKRYYGRILHYLKAKEYS
120 130 140 150 160
180 190 200
pF1KB7 DCAWEIVRVEIRRCLYYFYKFTALFRRK
::: :::::: : .:.. ..:. .:
NP_002 HCAWTIVRVEILRNFYFINRLTGYLRN
170 180
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 263 init1: 173 opt: 173 Z-score: 190.2 bits: 42.0 E(85289): 0.00074
Smith-Waterman score: 297; 32.0% identity (60.0% similar) in 200 aa overlap (12-207:3-188)
10 20 30 40 50
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
: . .::.... . :: :.: ..: . . : :..:. :
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTH-SLGNRRALILLAQMGRISPF
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
::.. : :::: .. .: .: . ....:: :.::.:: . . :.. :....
NP_067 SCLKDRHDFGLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFST
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
: :: . :. :. .. . :. :.:. : : .:.::.:: .: ::
NP_067 ELYQQLNNLEACVIQEVGM-EETPLMNED------------SILAVRKYFQRITLYLTEK
120 130 140 150
180 190 200
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
::: ::::.::.:: : : . .. ..:::
NP_067 KYSPCAWEVVRAEIMRSLSFSTNLQKILRRKD
160 170 180
>>NP_002168 (OMIM: 147553) interferon omega-1 precursor (195 aa)
initn: 278 init1: 163 opt: 170 Z-score: 187.0 bits: 41.5 E(85289): 0.0011
Smith-Waterman score: 316; 34.2% identity (60.9% similar) in 184 aa overlap (27-207:21-188)
10 20 30 40 50
pF1KB7 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVH--LRRVTWQNLRHLSSMSNSFPVE
:: :.: . : : : : :... .: :
NP_002 MALLFPLLAALVMTSYSPVGSLGCDLPQNHGLLSRNTLVLLHQMRRIS---PFL
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 CLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIF-SQHTFKYWKERHLKQIQIG
::.. :..:::... .: .: . ....:: : :..: .... :. : :.. :
NP_002 CLKDRRDFRFPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 LDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKK
: :: ..:. :: . .:.:. .. .:. : :::::. : .:::::
NP_002 LHQQLQHLETCLLQVVGEGESAGAIS----SPA---------LTLRRYFQGIRVYLKEKK
120 130 140 150
180 190 200
pF1KB7 YSDCAWEIVRVEIRRCLYYFYKFTALFRRK
:::::::.::.:: . :. .. .: :
NP_002 YSDCAWEVVRMEIMKSLFLSTNMQERLRSKDRDLGSS
160 170 180 190
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 238 init1: 168 opt: 168 Z-score: 185.2 bits: 41.1 E(85289): 0.0014
Smith-Waterman score: 266; 30.5% identity (58.5% similar) in 200 aa overlap (12-207:3-188)
10 20 30 40 50
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
: . .::.... . :: :.: ..: . . : :..:.
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTH-SLGNRRALILLAQMGRISHF
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
::.. : .:.: .. : .: . ....:: :.::.:: . . :.. :....
NP_066 SCLKDRHDFGFPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFST
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
: :: . :. :. .. . :. :.:. : : .:.::.:: .: ::
NP_066 ELYQQLNDLEACVIQEVGV-EETPLMNED------------SILAVRKYFQRITLYLTEK
120 130 140 150
180 190 200
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
::: ::::.::.:: : : . .. .:::
NP_066 KYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
160 170 180
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 244 init1: 159 opt: 164 Z-score: 181.2 bits: 40.4 E(85289): 0.0024
Smith-Waterman score: 272; 30.5% identity (58.5% similar) in 200 aa overlap (12-207:3-188)
10 20 30 40 50
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
: . .::.... . :: :.: ..: . . : :..:. :
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTH-SLGNRRALILLAQMGRISPF
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
::.. : .::: .. .: .: . ....:: :.::.:: . . :.. :....
NP_002 SCLKDRHDFGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFST
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
:.:: . :. :. .. . :. :. . : : ...::.:: .: ::
NP_002 ELNQQLNDLEACVIQEVGV-EETPLMNVD------------SILAVKKYFQRITLYLTEK
120 130 140 150
180 190 200
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
::: ::::.::.:: : . : .:::
NP_002 KYSPCAWEVVRAEIMRSFSLSKIFQERLRRKE
160 170 180
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 285 init1: 163 opt: 163 Z-score: 180.2 bits: 40.2 E(85289): 0.0027
Smith-Waterman score: 302; 32.0% identity (60.0% similar) in 200 aa overlap (12-207:3-188)
10 20 30 40 50
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
: . ..:.. . .. :: ::: ..: . ..: ...: :
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTH-SLNNRRTLMLMAQMRRISPF
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
::.. ::.::: .. .: .: . ....:: :.::.:: ... : : :... :
NP_002 SCLKDRHDFEFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
: :: . :. :. .. . :. :.:. : : ...::.:: .: ::
NP_002 ELFQQMNDLEACVIQEVGV-EETPLMNED------------SILAVKKYFQRITLYLMEK
120 130 140 150
180 190 200
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
::: ::::.::.:: : : . .. .:::
NP_002 KYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
160 170 180
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 252 init1: 163 opt: 163 Z-score: 180.2 bits: 40.2 E(85289): 0.0027
Smith-Waterman score: 283; 31.0% identity (60.0% similar) in 200 aa overlap (12-207:3-188)
10 20 30 40 50
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
: . .::.... . :: :.: ..: . . : :..:. :
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTH-SLGNRRALILLGQMGRISPF
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
::.. :..::: .. .: .: . ....:: :.::.:: . . :.. :....
NP_002 SCLKDRHDFRIPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFST
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
: :: . :. :. .. . :. :.:. : : .:.::.:: .: :.
NP_002 ELYQQLNDLEACVIQEVGV-EETPLMNED------------SILAVRKYFQRITLYLIER
120 130 140 150
180 190 200
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
::: ::::.::.:: : : . .. .:::
NP_002 KYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
160 170 180
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 233 init1: 158 opt: 162 Z-score: 179.2 bits: 40.0 E(85289): 0.0031
Smith-Waterman score: 267; 31.8% identity (55.9% similar) in 195 aa overlap (14-207:8-188)
10 20 30 40 50 60
pF1KB7 MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECL
: .:. . .. :: :.: ..: . ..: :..:: : ::
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETH-SLDNRRTLMLLAQMSRISPSSCL
10 20 30 40 50
70 80 90 100 110
pF1KB7 RENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQIGLD
. : .::: .. .: .: ....:. : ::.:. . . : : : .. :
NP_076 MDRHDFGFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 QQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYS
:: . :. :. :.: . .: .: : : ...::.:: .: :::::
NP_076 QQLNDLEACV---------MQEERVGETPLMNAD----SILAVKKYFRRITLYLTEKKYS
120 130 140 150 160
180 190 200
pF1KB7 DCAWEIVRVEIRRCLYYFYKFTALFRRK
::::.::.:: : : .. .:::
NP_076 PCAWEVVRAEIMRSLSLSTNLQERLRRKE
170 180
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 233 init1: 158 opt: 162 Z-score: 179.1 bits: 40.0 E(85289): 0.0031
Smith-Waterman score: 264; 31.6% identity (56.1% similar) in 196 aa overlap (16-207:8-189)
10 20 30 40 50
pF1KB7 MSTKPDMIQKCLWLEILMGIFI---AGTLSLDCNLLNVHLRRVTWQNLRHLSSMSNSFPV
.::.. . .. :: :.: ..: . ..: :..:: :
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLD-NRRTLMLLAQMSRISPS
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFS-QHTFKYWKERHLKQIQI
:: . : .::: .. .: .: ....:. : ::.:. . . : : : ..
NP_008 SCLMDRHDFGFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 GLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEK
: :: . :. :. :.: . .: .: : : ...::.:: .: ::
NP_008 ELYQQLNDLEACV---------MQEERVGETPLMNAD----SILAVKKYFRRITLYLTEK
120 130 140 150
180 190 200
pF1KB7 KYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
::: ::::.::.:: : : .. .:::
NP_008 KYSPCAWEVVRAEIMRSLSLSTNLQERLRRKE
160 170 180 190
207 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:05:36 2016 done: Fri Nov 4 06:05:37 2016
Total Scan time: 4.090 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]