Result of FASTA (omim) for
pFN21AB7035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7035, 426 aa
1>>>pF1KB7035 426 - 426 aa - 426 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5955+/-0.000304; mu= 17.2265+/- 0.019
mean_var=83.9208+/-16.654, 0's: 0 Z-trim(117.8): 71 B-trim: 1066 in 1/53
Lambda= 0.140004
statistics sampled from 29993 (30064) to 29993 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.352), width: 16
Scan time: 8.420
The best scores are: opt bits E(85289)
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 2895 594.2 2e-169
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 2895 594.2 2e-169
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 2895 594.3 2.3e-169
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 2895 594.3 2.5e-169
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 700 150.9 5.7e-36
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 523 115.1 3e-25
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 500 110.4 7.4e-24
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 393 88.7 1.8e-17
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 393 88.8 2.6e-17
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 380 86.2 1.5e-16
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 368 83.8 9.6e-16
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 361 82.3 2.1e-15
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 361 82.3 2.1e-15
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 361 82.4 2.3e-15
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 361 82.4 2.3e-15
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 361 82.4 2.3e-15
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 361 82.4 2.3e-15
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 358 81.8 3.5e-15
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 357 81.5 3.8e-15
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 350 80.2 1.1e-14
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 344 78.8 1.7e-14
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 344 79.0 2.8e-14
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 342 78.6 4e-14
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 340 78.2 4.6e-14
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390) 317 73.5 1.1e-12
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391) 317 73.5 1.1e-12
NP_003230 (OMIM: 107970,190230,615582) transformin ( 412) 317 73.5 1.1e-12
NP_001316868 (OMIM: 107970,190230,615582) transfor ( 412) 317 73.5 1.1e-12
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 313 72.5 1.2e-12
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 317 73.6 1.3e-12
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 317 73.6 1.3e-12
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 317 73.6 1.3e-12
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 313 72.6 1.7e-12
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 312 72.5 2.4e-12
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 299 69.9 1.5e-11
NP_003229 (OMIM: 190220,614816) transforming growt ( 414) 297 69.5 1.8e-11
NP_001129071 (OMIM: 190220,614816) transforming gr ( 442) 297 69.5 1.9e-11
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 293 68.7 3.3e-11
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 277 65.4 3.1e-10
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 269 63.9 1e-09
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 241 58.0 3.4e-08
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366) 241 58.1 4.3e-08
NP_001275756 (OMIM: 601918) growth/differentiation ( 366) 241 58.1 4.3e-08
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366) 241 58.1 4.3e-08
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366) 241 58.1 4.3e-08
NP_001275755 (OMIM: 601918) growth/differentiation ( 366) 241 58.1 4.3e-08
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366) 241 58.1 4.3e-08
NP_001275754 (OMIM: 601918) growth/differentiation ( 366) 241 58.1 4.3e-08
NP_001275757 (OMIM: 601918) growth/differentiation ( 366) 241 58.1 4.3e-08
NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 241 58.1 4.3e-08
>>NP_002183 (OMIM: 147290) inhibin beta A chain prepropr (426 aa)
initn: 2895 init1: 2895 opt: 2895 Z-score: 3162.5 bits: 594.2 E(85289): 2e-169
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
370 380 390 400 410 420
pF1KB7 EECGCS
::::::
NP_002 EECGCS
>>XP_016867665 (OMIM: 147290) PREDICTED: inhibin beta A (426 aa)
initn: 2895 init1: 2895 opt: 2895 Z-score: 3162.5 bits: 594.2 E(85289): 2e-169
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
370 380 390 400 410 420
pF1KB7 EECGCS
::::::
XP_016 EECGCS
>>XP_016867664 (OMIM: 147290) PREDICTED: inhibin beta A (483 aa)
initn: 2895 init1: 2895 opt: 2895 Z-score: 3161.8 bits: 594.3 E(85289): 2.3e-169
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:58-483)
10 20 30
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHS
::::::::::::::::::::::::::::::
XP_016 KSTHTKKPAREGGGKAGPFKKAITTTFAARMPLLWLRGFLLASCWIIVRSSPTPGSEGHS
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB7 AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB7 HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVV
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB7 ERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKV
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB7 VDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGK
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB7 KKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB7 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
390 400 410 420 430 440
400 410 420
pF1KB7 CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
::::::::::::::::::::::::::::::::::::
XP_016 CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
450 460 470 480
>>XP_016867663 (OMIM: 147290) PREDICTED: inhibin beta A (548 aa)
initn: 2895 init1: 2895 opt: 2895 Z-score: 3161.0 bits: 594.3 E(85289): 2.5e-169
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:123-548)
10 20 30
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHS
::::::::::::::::::::::::::::::
XP_016 KSTHTKKPAREGGGKAGPFKKAITTTFAARMPLLWLRGFLLASCWIIVRSSPTPGSEGHS
100 110 120 130 140 150
40 50 60 70 80 90
pF1KB7 AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL
160 170 180 190 200 210
100 110 120 130 140 150
pF1KB7 HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVV
220 230 240 250 260 270
160 170 180 190 200 210
pF1KB7 ERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKV
280 290 300 310 320 330
220 230 240 250 260 270
pF1KB7 VDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGK
340 350 360 370 380 390
280 290 300 310 320 330
pF1KB7 KKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF
400 410 420 430 440 450
340 350 360 370 380 390
pF1KB7 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
460 470 480 490 500 510
400 410 420
pF1KB7 CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
::::::::::::::::::::::::::::::::::::
XP_016 CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
520 530 540
>>NP_002184 (OMIM: 147390) inhibin beta B chain prepropr (407 aa)
initn: 1151 init1: 437 opt: 700 Z-score: 766.7 bits: 150.9 E(85289): 5.7e-36
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (22-426:43-407)
10 20 30 40 50
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
: ::: : : : ::. :... .
NP_002 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB7 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
...::::.:::. :... ::..:. :::::...:.::::.::: :.: ::: :. .
NP_002 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
80 90 100 110 120 130
120 130 140 150 160
pF1KB7 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
. .:..::::.:::. ...: :.: ::.::.. : .: .::.::. : :
NP_002 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB7 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
..: ...: . ::.: : :.: ... :: :: ..: ::.::.
NP_002 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
200 210 220 230
230 240 250 260 270 280
pF1KB7 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
. .:: :...:. :.. . :..::: .. :.. . ::
NP_002 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
240 250 260
290 300 310 320 330 340
pF1KB7 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
.:::::...::: . : :: :.:::::::..:.::..:::..:. ::::::::::.
NP_002 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB7 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.:::: :::::
NP_002 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
330 340 350 360 370 380
410 420
pF1KB7 YDDGQNIIKKDIQNMIVEECGCS
.:: ::.:.:. :::::::::.
NP_002 FDDEYNIVKRDVPNMIVEECGCA
390 400
>>NP_005529 (OMIM: 601233) inhibin beta C chain prepropr (352 aa)
initn: 684 init1: 501 opt: 523 Z-score: 574.4 bits: 115.1 E(85289): 3e-25
Smith-Waterman score: 679; 32.6% identity (56.0% similar) in 423 aa overlap (9-426:5-352)
10 20 30 40 50 60
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
.::: . . :: . :. ::.:. .: .. ... ... .:.
NP_005 MTSSLLLAFLLLAPTTVATPRAGGQ-----CPACGGPTL--ELESQRELLLDLAKR
10 20 30 40
70 80 90 100 110 120
pF1KB7 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
::. ::: .:: ...:: .::: .:...:: : . .::. ::
NP_005 SILDKLHLTQRPTLNRPVSRAALRTALQHLH----GVPQGALLEDN----------REQE
50 60 70 80 90
130 140 150 160 170
pF1KB7 SEIITFAESGTA-----RKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRL
:::.:::.: . : .:: .. ..: : ..: . .:...:. . :: .
NP_005 CEIISFAETGLSTINQTRLDFHFSSDRTAGDREV-QQASLMFFVQLPSNTTWTLKVRV--
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 FQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGK
: : . .. : .. :: ::: : :: .:.. : .::.
NP_005 ----------LVLGPHNTNLTLA---TQYLLE---VDA--SGWHQLPLGPEAQAACSQGH
160 170 180 190
240 250 260 270 280 290
pF1KB7 SSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLML
.:.. . . : . .:..: ::: .::::.
NP_005 LTLELVL---EGQVAQSSVIL--------------------GGA--------AHRPFV--
200 210 220
300 310 320 330 340 350
pF1KB7 QARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECP
:: :. .:::..:.: .::...:::.:..:::.:::: : :: :.: :.::
NP_005 AARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCP
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB7 SHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDI
:::: : . :::..:.: . . .. :::::: ::.:.:::: .::.: ::
NP_005 LHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDI
290 300 310 320 330 340
420
pF1KB7 QNMIVEECGCS
.:.:: ::::
NP_005 PDMVVEACGCS
350
>>NP_113667 (OMIM: 612031) inhibin beta E chain prepropr (350 aa)
initn: 661 init1: 317 opt: 500 Z-score: 549.3 bits: 110.4 E(85289): 7.4e-24
Smith-Waterman score: 612; 32.0% identity (55.8% similar) in 425 aa overlap (4-426:8-350)
10 20 30 40 50
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-
::: :: : .::.. : :: ::::. . : .:... .:
NP_113 MRLPDVQLWL--VLL---WALVRAQGT-GSV-------CPSCGGSKL---APQAERALVL
10 20 30 40
60 70 80 90 100 110
pF1KB7 EAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGE-NGYVEIEDDIGRRAEMN
: .:..::. ::: .:: .:.: :.::: :.:.:. :.:. :: ... : ..
NP_113 ELAKQQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSVAPGNG-----EEVISFATVT
50 60 70 80 90
120 130 140 150 160 170
pF1KB7 ELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIR
. : ..:: : : :. : . .:..:: . .: : . .:
NP_113 DSTSAYSSLLTFHLS-TPRS--HH-----------LYHARLWLHV-LPTLPGT---LCLR
100 110 120 130 140
180 190 200 210 220 230
pF1KB7 LFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQG
.:. : . .. : :. ::.:. . . ::.. . :: : .:
NP_113 IFRW----------GPRRRRQG-----SRTLLAEHHIT--NLGWHTLTLPSSGLRGEKSG
150 160 170 180
240 250 260 270 280 290
pF1KB7 KSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLM
: ... :. . : : : :. .. . :: ..:::
NP_113 --VLKLQLDCRPLE--GNSTVT-GQPRRLLDT------------AG-------HQQPFLE
190 200 210 220
300 310 320 330 340 350
pF1KB7 LQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGEC
:. : .: : ::: :. . .::... .:.:...:: :::. : ::. ::: :.:
NP_113 LKIRANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQC
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB7 PSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKD
: :.::. : . ::::.:.. .....:. :::::: ::.:.:: : . :..: :
NP_113 PPHLAGSPGIAASFHSAVFS--LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTD
290 300 310 320 330
420
pF1KB7 IQNMIVEECGCS
. .:.:: ::::
NP_113 VPDMVVEACGCS
340 350
>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b (240 aa)
initn: 400 init1: 203 opt: 393 Z-score: 434.8 bits: 88.7 E(85289): 1.8e-17
Smith-Waterman score: 417; 31.0% identity (62.8% similar) in 226 aa overlap (205-425:35-239)
180 190 200 210 220 230
pF1KB7 LFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQG
::. ..:. : :. : :. ...: ::
XP_011 LGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQG
10 20 30 40 50 60
240 250 260 270 280 290
pF1KB7 KSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLM
... . . .: ..: .:.. . ::.. .. ::.:.
XP_011 HANHGFVVEVAHLEE---------------KQGVSKRHVRISRSLHQDEHSWSQIRPLLV
70 80 90 100
300 310 320 330 340 350
pF1KB7 LQARQSEDHP-HRRRRRGLECDGKVNI--CCKKQ-FFVSFKDIGWNDWIIAPSGYHANYC
..... :: :.:..: . . . ::.. ..:.:.:.::::::.:: :::: ::
XP_011 TFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYC
110 120 130 140 150 160
360 370 380 390 400
pF1KB7 EGECPSHIAG-TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQN
.:::: .: .... .. .:..: . .. : :.:::::.: .:::: :....
XP_011 HGECPFPLADHLNSTNHAIVQTLVN--SVNSKIP----KACCVPTELSAISMLYLDENEK
170 180 190 200 210 220
410 420
pF1KB7 IIKKDIQNMIVEECGCS
.. :. :.:.:: :::
XP_011 VVLKNYQDMVVEGCGCR
230 240
>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene (396 aa)
initn: 423 init1: 203 opt: 393 Z-score: 431.8 bits: 88.8 E(85289): 2.6e-17
Smith-Waterman score: 458; 26.8% identity (56.7% similar) in 406 aa overlap (33-425:26-395)
10 20 30 40 50 60
pF1KB7 LLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQP--EMVEAVKK
:. .:: . :.::: :.. .
NP_001 MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFEL
10 20 30 40 50
70 80 90 100 110
pF1KB7 HILNMLHLKKRPDVTQP--VPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELME
..:.:. ::.:: .. :: .:. :. : :. : . . . . ::. . ..
NP_001 RLLSMFGLKQRPTPSRDAVVPPY-MLDLYRR-HSGQPGSPAPDHRLERAASRANTVRSFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 QTSEIITFAE-SGTARKTLHFEISKEGSDLSVVERAEVWLF---LKVPKANRTRTKVTIR
. . . : :: . . . :..:. .. . ::. .: .. .: . . :
NP_001 HEESLEELPETSGKTTRRFFFNLSSIPTE-EFITSAELQVFREQMQDALGNNSSFHHRIN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 LFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQG
... : : :.. : ::. ..:. : :. : :. ...: ::
NP_001 IYEIIK-PA----TANSKFPV-------TRLLDTRLVNQNASRWESFDVTPAVMRWTAQG
180 190 200 210 220
240 250 260 270 280 290
pF1KB7 KSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLM
... . : : .:..: .:.. . ::.. .. ::.:.
NP_001 HANHGFVVEV-------AHL--------EEKQGVSKRHVRISRSLHQDEHSWSQIRPLLV
230 240 250 260
300 310 320 330 340 350
pF1KB7 LQARQSEDHP-HRRRRRGLECDGKVNI--CCKKQ-FFVSFKDIGWNDWIIAPSGYHANYC
..... :: :.:..: . . . ::.. ..:.:.:.::::::.:: :::: ::
NP_001 TFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYC
270 280 290 300 310 320
360 370 380 390 400
pF1KB7 EGECPSHIAG-TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQN
.:::: .: .... .. .:..: . .. : :.:::::.: .:::: :....
NP_001 HGECPFPLADHLNSTNHAIVQTLVNS--VNSKIP----KACCVPTELSAISMLYLDENEK
330 340 350 360 370
410 420
pF1KB7 IIKKDIQNMIVEECGCS
.. :. :.:.:: :::
NP_001 VVLKNYQDMVVEGCGCR
380 390
>>NP_065685 (OMIM: 606522,613702,613703,613704) growth/d (364 aa)
initn: 416 init1: 211 opt: 380 Z-score: 418.1 bits: 86.2 E(85289): 1.5e-16
Smith-Waterman score: 380; 38.5% identity (68.5% similar) in 143 aa overlap (289-425:230-363)
260 270 280 290 300 310
pF1KB7 KKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRG-----LE
: .:.. .. :: :.:: . :
NP_065 LFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLS
200 210 220 230 240 250
320 330 340 350 360 370
pF1KB7 CDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECP-SHIAGTSGSSLSFHSTV
: :.: ..:.:..:.:.::. :::::.:. ::::.:::: : . ..:. .: ...
NP_065 CK---NLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQAL
260 270 280 290 300 310
380 390 400 410 420
pF1KB7 INHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
:.. .: .. :.:::: :.:::: :...:.: . ..:.:.::::
NP_065 -----MHAVDPEIP-QAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
320 330 340 350 360
426 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 04:08:59 2016 done: Fri Nov 4 04:09:00 2016
Total Scan time: 8.420 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]