Result of FASTA (ccds) for
pFN21AB5344
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5344, 232 aa
1>>>pF1KB5344 232 - 232 aa - 232 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0322+/-0.000826; mu= 16.2084+/- 0.051
mean_var=76.2959+/-15.514, 0's: 0 Z-trim(109.0): 162 B-trim: 642 in 2/50
Lambda= 0.146833
statistics sampled from 10425 (10602) to 10425 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.326), width: 16
Scan time: 2.200
The best scores are: opt bits E(32554)
CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 1542 335.6 1.7e-92
CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 988 218.2 3.7e-57
CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 831 185.0 3.6e-47
CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 550 125.4 2.7e-29
CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 546 124.5 4.8e-29
CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 543 123.9 7.5e-29
CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 526 120.3 9.6e-28
CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 501 115.0 3.8e-26
CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 495 113.7 8.5e-26
CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 495 113.7 8.5e-26
CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 492 113.1 1.3e-25
CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 488 112.2 2.3e-25
CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 467 107.8 5.2e-24
CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 446 103.4 1.2e-22
CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 438 101.8 4.6e-22
CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 436 101.2 4.9e-22
CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 435 101.0 5.7e-22
CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 434 100.8 7.2e-22
CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 414 96.6 1.4e-20
CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 332 79.2 2.1e-15
CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 293 71.0 6.9e-13
CCDS7261.1 RHOBTB1 gene_id:9886|Hs108|chr10 ( 696) 290 70.8 2.6e-12
CCDS6034.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 727) 274 67.4 2.8e-11
CCDS55211.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 734) 274 67.4 2.8e-11
CCDS55210.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 749) 274 67.4 2.9e-11
>>CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 (232 aa)
initn: 1542 init1: 1542 opt: 1542 Z-score: 1774.2 bits: 335.6 E(32554): 1.7e-92
Smith-Waterman score: 1542; 100.0% identity (100.0% similar) in 232 aa overlap (1-232:1-232)
10 20 30 40 50 60
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
130 140 150 160 170 180
190 200 210 220 230
pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
190 200 210 220 230
>>CCDS2190.1 RND3 gene_id:390|Hs108|chr2 (244 aa)
initn: 970 init1: 936 opt: 988 Z-score: 1139.6 bits: 218.2 E(32554): 3.7e-57
Smith-Waterman score: 1001; 58.2% identity (83.2% similar) in 244 aa overlap (1-232:1-244)
10 20 30 40 50
pF1KB5 MKERRAPQPVVAR----------CKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENY
:::::: : . .. ::.:.::: ::::::.:.:.::::.::.:::::::::
CCDS21 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 TACLETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTE
:: .: . ::.::::::::::::::::::: : ::::::.:::::::::.::.::::. :
CCDS21 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 ILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAF
: ..::.:..::.:::.:::::.:::.:::...:.:.::.:: .:::.:: :.: ::.
CCDS21 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
130 140 150 160 170 180
180 190 200 210 220
pF1KB5 TSEKSIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSEL--ISSTFKKEKAKS
::.:...::..:.. :.:: . ... . .::. :.::: :: ... ..:.::::
CCDS21 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
190 200 210 220 230 240
230
pF1KB5 CSIM
:..:
CCDS21 CTVM
>>CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 (227 aa)
initn: 817 init1: 792 opt: 831 Z-score: 960.3 bits: 185.0 E(32554): 3.6e-47
Smith-Waterman score: 831; 53.4% identity (82.4% similar) in 221 aa overlap (13-232:7-227)
10 20 30 40 50 60
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
:::.:.:::..:::::.:::.::: :: .::::::::::: .: ...:
CCDS11 MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRR
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
.::..:::::: :::::::: : ::::::.:::::::::.::.::::. : ..::...:
CCDS11 IELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
.:.::: :.::::.:: :::.:. :...::: ..:::.:: :.: :. .::.:....:
CCDS11 VLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVF
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELIS-STFKKEKAKSCSIM
..:.. :.. ... : .: .: .: . . . ..:..::::..:
CCDS11 HVATVASLGRGHRQLRRTDSRRGMQRSAQLSGRPDRGNEGEIHKDRAKSCNLM
180 190 200 210 220
>>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa)
initn: 554 init1: 537 opt: 550 Z-score: 639.5 bits: 125.4 E(32554): 2.7e-29
Smith-Waterman score: 550; 45.9% identity (77.9% similar) in 172 aa overlap (13-184:5-175)
10 20 30 40 50 60
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
: :::.::: :::: .: :..:: .::.:::::::::.: .:.. ..
CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
:::.::::.:. :: .::: : :.:..:.::.:. :..... .:: :. .::.. .
CCDS27 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
.:.: : :::.: : ::...:: :.. :.: .:...:: :.: :: :.. ... .:
CCDS27 ILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKD-GVREVF
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
. :.
CCDS27 EMATRAALQARRGKKKSGCLVL
180 190
>>CCDS854.1 RHOC gene_id:389|Hs108|chr1 (193 aa)
initn: 550 init1: 533 opt: 546 Z-score: 635.0 bits: 124.5 E(32554): 4.8e-29
Smith-Waterman score: 546; 46.5% identity (76.2% similar) in 172 aa overlap (13-184:5-175)
10 20 30 40 50 60
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
: :::.::: :::: .: :..:: .::.::::::::: : .:.. ..
CCDS85 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
:::.::::.:. :: .::: : :.:..:.::.:. :..... .:: :. .::.. .
CCDS85 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
.:.: : ::: : : ::...:: :. :.: .:....: ::: :: :.: ... .:
CCDS85 ILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKE-GVREVF
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
. :.
CCDS85 EMATRAGLQVRKNKRRRGCPIL
180 190
>>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa)
initn: 540 init1: 518 opt: 543 Z-score: 631.4 bits: 123.9 E(32554): 7.5e-29
Smith-Waterman score: 543; 44.9% identity (76.4% similar) in 178 aa overlap (13-190:5-181)
10 20 30 40 50 60
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
: :::.::: :::: .: :..:: .::.:::::::::.: .:.. ..
CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
:::.::::.:. :: .::: : :.:..:.::... :..... .:: :. .::.. .
CCDS16 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
.:.. : :::.: . ::...:: :. ..: :.: .. : ::: :: :.: ... .:
CCDS16 ILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKE-GVREVF
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
.::. :.:
CCDS16 ETATRAALQKRYGSQNGCINCCKVL
180 190
>>CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 (210 aa)
initn: 500 init1: 500 opt: 526 Z-score: 611.6 bits: 120.3 E(32554): 9.6e-28
Smith-Waterman score: 526; 40.8% identity (72.8% similar) in 184 aa overlap (6-189:11-192)
10 20 30 40 50
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLE
:: : : :.::::: ::::..:.:.: .::.:.::::: : . :.
CCDS81 MTAAQAAGEEAP-PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 TEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYC
.. . :.: .:::.:. :: .::: : :....:::::.. :.. :. ...: :. .:
CCDS81 VKGKPVHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKS
.. ....::::::: : : . .: .. :..:..: .:...:: ::: :: . .
CCDS81 KKVPIIVVGCKTDLRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHD-N
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 IHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
.:..:. :. . :.
CCDS81 VHAVFQEAAEVALSSRGRNFWRRITQGFCVVT
180 190 200 210
>>CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 (211 aa)
initn: 481 init1: 481 opt: 501 Z-score: 582.9 bits: 115.0 E(32554): 3.8e-26
Smith-Waterman score: 501; 40.2% identity (67.7% similar) in 189 aa overlap (1-189:7-194)
10 20 30 40 50
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACL
. . :: : . :.:.::: ::::..:.: .. .:: :.:.:::.::: .
CCDS92 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 ETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDY
. ..: :.:.::.:. :: .::: :... ::.:.:. : . :..: :: :. .
CCDS92 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 CPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEK
: . ..::::::::: : : .: . ::.: :: . .:. : .::: :: :
CCDS92 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRE-
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 SIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
.....:: :. . :.
CCDS92 NVEDVFREAAKVALSALKKAQRQKKRRLCLLL
180 190 200 210
>>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa)
initn: 460 init1: 460 opt: 495 Z-score: 576.6 bits: 113.7 E(32554): 8.5e-26
Smith-Waterman score: 495; 40.0% identity (70.8% similar) in 185 aa overlap (15-197:5-185)
10 20 30 40 50 60
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
: :.::: ::: .: . . .: :.::::.::.: . .. .
CCDS53 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKP
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
:.:.::::.:. :: .::: : ..:. :.::.. : . ... :: :. .::.: .
CCDS53 VNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
.:.: : ::: : .:. .:...: .::.: :: :.::..:: ::: ::.: .......:
CCDS53 ILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT-QRGLKTVF
120 130 140 150 160
190 200 210 220 230
pF1KB5 RTA--SMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
: ..:: : :. ..
CCDS53 DEAIRAVLC---PPPVKKRKRKCLLL
170 180 190
>>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa)
initn: 471 init1: 456 opt: 495 Z-score: 576.6 bits: 113.7 E(32554): 8.5e-26
Smith-Waterman score: 495; 40.3% identity (70.2% similar) in 191 aa overlap (15-203:5-191)
10 20 30 40 50 60
pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR
: :.::: ::: .: . . .: :.::::.::.: . .. .
CCDS13 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKP
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV
:.:.::::.:. :: .::: : ..:. :.::.. : . ... :: :. .:::: .
CCDS13 VNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF
.:.: : ::: : .:. .:...: :::.: :: :.::.. . ::: ::.: .......:
CCDS13 ILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALT-QRGLKTVF
120 130 140 150 160
190 200 210 220 230
pF1KB5 RTA--SMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
: ..:: :.: :.. . ::
CCDS13 DEAIRAVLC---PQPTRQQKRACSLL
170 180 190
232 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:38:37 2016 done: Fri Nov 4 03:38:37 2016
Total Scan time: 2.200 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]