Result of FASTA (omim) for
pFN21AA2011
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA2011, 1024 aa
1>>>pF1KA2011 1024 - 1024 aa - 1024 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.4034+/-0.000388; mu= -3.7583+/- 0.024
mean_var=447.9010+/-90.805, 0's: 0 Z-trim(124.6): 138 B-trim: 0 in 0/62
Lambda= 0.060601
statistics sampled from 46481 (46643) to 46481 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.547), width: 16
Scan time: 15.000
The best scores are: opt bits E(85289)
XP_011538270 (OMIM: 602327) PREDICTED: PH and SEC7 (1024) 6983 625.6 4.1e-178
XP_016871923 (OMIM: 602327) PREDICTED: PH and SEC7 (1024) 6983 625.6 4.1e-178
XP_016871922 (OMIM: 602327) PREDICTED: PH and SEC7 (1024) 6983 625.6 4.1e-178
NP_001257894 (OMIM: 602327) PH and SEC7 domain-con (1024) 6983 625.6 4.1e-178
XP_011538271 (OMIM: 602327) PREDICTED: PH and SEC7 (1024) 6983 625.6 4.1e-178
NP_002770 (OMIM: 602327) PH and SEC7 domain-contai (1024) 6983 625.6 4.1e-178
NP_001257895 (OMIM: 602327) PH and SEC7 domain-con ( 645) 4292 390.2 2e-107
XP_016868750 (OMIM: 614440) PREDICTED: PH and SEC7 (1014) 1919 182.9 7.8e-45
XP_016868749 (OMIM: 614440) PREDICTED: PH and SEC7 (1046) 1919 182.9 7.9e-45
NP_056125 (OMIM: 614440) PH and SEC7 domain-contai (1047) 1919 182.9 7.9e-45
XP_016868748 (OMIM: 614440) PREDICTED: PH and SEC7 (1060) 1919 182.9 8e-45
XP_016868747 (OMIM: 614440) PREDICTED: PH and SEC7 (1067) 1919 182.9 8.1e-45
XP_016868754 (OMIM: 614440) PREDICTED: PH and SEC7 ( 511) 1904 181.3 1.2e-44
NP_996792 (OMIM: 614440) PH and SEC7 domain-contai ( 513) 1904 181.3 1.2e-44
NP_036587 (OMIM: 614442) PH and SEC7 domain-contai (1056) 1440 141.0 3.2e-32
XP_005263691 (OMIM: 614442) PREDICTED: PH and SEC7 (1056) 1440 141.0 3.2e-32
XP_006712455 (OMIM: 614442) PREDICTED: PH and SEC7 (1055) 1435 140.6 4.4e-32
XP_006712456 (OMIM: 614442) PREDICTED: PH and SEC7 ( 965) 1002 102.7 1e-20
XP_006712457 (OMIM: 614442) PREDICTED: PH and SEC7 ( 964) 997 102.3 1.4e-20
XP_011542770 (OMIM: 614440) PREDICTED: PH and SEC7 ( 997) 805 85.5 1.6e-15
XP_011542773 (OMIM: 614440) PREDICTED: PH and SEC7 ( 976) 798 84.9 2.4e-15
XP_011542775 (OMIM: 614440) PREDICTED: PH and SEC7 ( 972) 791 84.3 3.7e-15
XP_011542771 (OMIM: 614440) PREDICTED: PH and SEC7 ( 985) 791 84.3 3.7e-15
XP_011542769 (OMIM: 614440) PREDICTED: PH and SEC7 (1006) 791 84.3 3.8e-15
XP_016868751 (OMIM: 614440) PREDICTED: PH and SEC7 (1008) 791 84.3 3.8e-15
XP_016868753 (OMIM: 614440) PREDICTED: PH and SEC7 ( 701) 652 72.0 1.3e-11
XP_016868752 (OMIM: 614440) PREDICTED: PH and SEC7 ( 945) 652 72.1 1.6e-11
XP_011523777 (OMIM: 182115) PREDICTED: cytohesin-1 ( 322) 382 48.0 0.0001
XP_011523778 (OMIM: 182115) PREDICTED: cytohesin-1 ( 322) 382 48.0 0.0001
XP_016880827 (OMIM: 182115) PREDICTED: cytohesin-1 ( 338) 382 48.0 0.0001
NP_001278948 (OMIM: 182115) cytohesin-1 isoform 3 ( 339) 382 48.0 0.0001
NP_001278947 (OMIM: 182115) cytohesin-1 isoform 3 ( 339) 382 48.0 0.0001
XP_011523779 (OMIM: 182115) PREDICTED: cytohesin-1 ( 339) 382 48.0 0.0001
XP_016880826 (OMIM: 182115) PREDICTED: cytohesin-1 ( 380) 382 48.1 0.00011
NP_059430 (OMIM: 182115) cytohesin-1 isoform 2 [Ho ( 397) 382 48.1 0.00012
NP_004753 (OMIM: 182115) cytohesin-1 isoform 1 [Ho ( 398) 382 48.1 0.00012
XP_016880825 (OMIM: 182115) PREDICTED: cytohesin-1 ( 399) 382 48.1 0.00012
NP_004218 (OMIM: 605081) cytohesin-3 [Homo sapiens ( 399) 374 47.4 0.00019
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 384 49.0 0.00032
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 384 49.0 0.00032
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 384 49.0 0.00032
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 384 49.0 0.00032
XP_006723536 (OMIM: 602488) PREDICTED: cytohesin-2 ( 394) 358 46.0 0.00049
NP_004219 (OMIM: 602488) cytohesin-2 isoform 2 [Ho ( 399) 358 46.0 0.00049
NP_059431 (OMIM: 602488) cytohesin-2 isoform 1 [Ho ( 400) 358 46.0 0.0005
XP_006723535 (OMIM: 602488) PREDICTED: cytohesin-2 ( 421) 358 46.0 0.00051
NP_001304953 (OMIM: 606514) cytohesin-4 isoform 2 ( 337) 319 42.5 0.0047
XP_011528449 (OMIM: 606514) PREDICTED: cytohesin-4 ( 337) 319 42.5 0.0047
NP_037517 (OMIM: 606514) cytohesin-4 isoform 1 [Ho ( 394) 319 42.6 0.0052
NP_056047 (OMIM: 612118) IQ motif and SEC7 domain- ( 759) 318 42.8 0.0087
>>XP_011538270 (OMIM: 602327) PREDICTED: PH and SEC7 dom (1024 aa)
initn: 6983 init1: 6983 opt: 6983 Z-score: 3318.7 bits: 625.6 E(85289): 4.1e-178
Smith-Waterman score: 6983; 100.0% identity (100.0% similar) in 1024 aa overlap (1-1024:1-1024)
10 20 30 40 50 60
pF1KA2 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
970 980 990 1000 1010 1020
pF1KA2 RRKP
::::
XP_011 RRKP
>>XP_016871923 (OMIM: 602327) PREDICTED: PH and SEC7 dom (1024 aa)
initn: 6983 init1: 6983 opt: 6983 Z-score: 3318.7 bits: 625.6 E(85289): 4.1e-178
Smith-Waterman score: 6983; 100.0% identity (100.0% similar) in 1024 aa overlap (1-1024:1-1024)
10 20 30 40 50 60
pF1KA2 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
970 980 990 1000 1010 1020
pF1KA2 RRKP
::::
XP_016 RRKP
>>XP_016871922 (OMIM: 602327) PREDICTED: PH and SEC7 dom (1024 aa)
initn: 6983 init1: 6983 opt: 6983 Z-score: 3318.7 bits: 625.6 E(85289): 4.1e-178
Smith-Waterman score: 6983; 100.0% identity (100.0% similar) in 1024 aa overlap (1-1024:1-1024)
10 20 30 40 50 60
pF1KA2 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
970 980 990 1000 1010 1020
pF1KA2 RRKP
::::
XP_016 RRKP
>>NP_001257894 (OMIM: 602327) PH and SEC7 domain-contain (1024 aa)
initn: 6983 init1: 6983 opt: 6983 Z-score: 3318.7 bits: 625.6 E(85289): 4.1e-178
Smith-Waterman score: 6983; 100.0% identity (100.0% similar) in 1024 aa overlap (1-1024:1-1024)
10 20 30 40 50 60
pF1KA2 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
970 980 990 1000 1010 1020
pF1KA2 RRKP
::::
NP_001 RRKP
>>XP_011538271 (OMIM: 602327) PREDICTED: PH and SEC7 dom (1024 aa)
initn: 6983 init1: 6983 opt: 6983 Z-score: 3318.7 bits: 625.6 E(85289): 4.1e-178
Smith-Waterman score: 6983; 100.0% identity (100.0% similar) in 1024 aa overlap (1-1024:1-1024)
10 20 30 40 50 60
pF1KA2 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
970 980 990 1000 1010 1020
pF1KA2 RRKP
::::
XP_011 RRKP
>>NP_002770 (OMIM: 602327) PH and SEC7 domain-containing (1024 aa)
initn: 6983 init1: 6983 opt: 6983 Z-score: 3318.7 bits: 625.6 E(85289): 4.1e-178
Smith-Waterman score: 6983; 100.0% identity (100.0% similar) in 1024 aa overlap (1-1024:1-1024)
10 20 30 40 50 60
pF1KA2 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSG
970 980 990 1000 1010 1020
pF1KA2 RRKP
::::
NP_002 RRKP
>>NP_001257895 (OMIM: 602327) PH and SEC7 domain-contain (645 aa)
initn: 4292 init1: 4292 opt: 4292 Z-score: 2049.6 bits: 390.2 E(85289): 2e-107
Smith-Waterman score: 4292; 100.0% identity (100.0% similar) in 645 aa overlap (380-1024:1-645)
350 360 370 380 390 400
pF1KA2 EDEDDDEAGGEEDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAI
::::::::::::::::::::::::::::::
NP_001 MPLKSPVPFLPGTSPSADGPDSFSCVFEAI
10 20 30
410 420 430 440 450 460
pF1KA2 LESHRAKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESHRAKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSG
40 50 60 70 80 90
470 480 490 500 510 520
pF1KA2 TSSAADGPWTQRGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSAADGPWTQRGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDS
100 110 120 130 140 150
530 540 550 560 570 580
pF1KA2 DSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKL
160 170 180 190 200 210
590 600 610 620 630 640
pF1KA2 VAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDG
220 230 240 250 260 270
650 660 670 680 690 700
pF1KA2 AHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQ
280 290 300 310 320 330
710 720 730 740 750 760
pF1KA2 WAIDEEELRRSLSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WAIDEEELRRSLSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHA
340 350 360 370 380 390
770 780 790 800 810 820
pF1KA2 DPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASD
400 410 420 430 440 450
830 840 850 860 870 880
pF1KA2 YSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRP
460 470 480 490 500 510
890 900 910 920 930 940
pF1KA2 LLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEK
520 530 540 550 560 570
950 960 970 980 990 1000
pF1KA2 SRYSTYAALLRVKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRYSTYAALLRVKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRH
580 590 600 610 620 630
1010 1020
pF1KA2 SSEPRPGAGSGRRKP
:::::::::::::::
NP_001 SSEPRPGAGSGRRKP
640
>>XP_016868750 (OMIM: 614440) PREDICTED: PH and SEC7 dom (1014 aa)
initn: 1923 init1: 981 opt: 1919 Z-score: 925.9 bits: 182.9 E(85289): 7.8e-45
Smith-Waterman score: 1970; 48.5% identity (71.2% similar) in 718 aa overlap (331-1023:335-1012)
310 320 330 340 350
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDED-DDEAGG
:. ::: : ... ::. .::.
XP_016 SKVPRHLISSAGLCNSSSLTENVWDESWKAPSERPGTSSG---TFSPVRLDESGEDEVFL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA2 EEDVDDEVFEASEGARPGSRMP-----LKSPVPFLPGTSPSADGPDSFSCVFEAILESHR
.:. ... .. . : :. .:. . : . . :. : .: ::.::..
XP_016 QEN-KQHLEKTPKPERDRERISEQEEHVKGEDEDILGPGYTEDSTDVYSSQFETILDN--
370 380 390 400 410
420 430 440 450 460
pF1KA2 AKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSG-----
. : : :::.: : : . .:.::.: : . . : : ::
XP_016 --TSLYYSAESLETLYSE-P--DSYFSFEMPLTPMIQQRIKEGGQFL---ERTSGGGHQD
420 430 440 450 460 470
470 480 490 500 510 520
pF1KA2 -TSSAADGPWTQRGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAP----LGSEPPLSQ
: .::: .. : . .. : . : ::. ..: ::. ..
XP_016 ILSVSADGGIVM-GYS------SGVTNGLNDAS-----DSIYTKGTPEIAFWGSNAGVKT
480 490 500 510
530 540 550 560 570 580
pF1KA2 LVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNN
.. ::. ::: : . ..:::: ....:::.:::::::.:: :...:::.::::::
XP_016 TRLEAHSEMGSTEILEKETPENLSNGTSSNVEAAKRLAKRLYQLDRFKRSDVAKHLGKNN
520 530 540 550 560 570
590 600 610 620 630 640
pF1KA2 DFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEAL
.:::::: :::::: ::::::::.:: :.: ..:.:::::::::: :::.::: :::...
XP_016 EFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTI
580 590 600 610 620 630
650 660 670 680 690 700
pF1KA2 SSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIK
.:.::.: ::::.::::::::::::::.::: .::.::.:.:.: :: ..::::::.:::
XP_016 ASQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSIK
640 650 660 670 680 690
710 720 730 740 750
pF1KA2 NEKLQWAIDEEELRRSLSELADP-----NPKVIKRISGGSGSGSSPFLDLTPEPGAAVYK
::::.::.:.:: ..: :: .. .::.:.:: :: ..::::. .:.:::::
XP_016 NEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISRI----GSTTNPFLDIPHDPNAAVYK
700 710 720 730 740 750
760 770 780 790 800 810
pF1KA2 HGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISI
: :.::.::: : .::::::::::.:...::: .:::::.:::: ::::: .::::.:.
XP_016 SGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSV
760 770 780 790 800 810
820 830 840 850 860 870
pF1KA2 HHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAA
:::::..:.:: :.:.:: :.::::::.:::. : :.::.::..:: :::.:::::::::
XP_016 HHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAA
820 830 840 850 860 870
880 890 900 910 920 930
pF1KA2 VSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQR
..:::::::::::...:.::::::...::.::: ...:: :::. :: ..:...: .
XP_016 IGSQKKFSRPLLPATTTKLSQEEQLKSHESKLKQITTELAEHRSYPPDKKVKAKDVDEYK
880 890 900 910 920 930
940 950 960 970 980 990
pF1KA2 QKEAYLEFEKSRYSTYAALLRVKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPK
:. ::::::.:: :... :: :..:: :.. : :: :::::::.:
XP_016 LKDHYLEFEKTRYEMYVSI----LKEGGKEL------LSNDESEAAGLKKSHSSPSLNPD
940 950 960 970 980
1000 1010 1020
pF1KA2 PSS-QPRAQRHSSE---PRPGAGSGRRKP
: ...:. :: :: . : ..:
XP_016 TSPITAKVKRNVSERKDHRPETPSIKQKVT
990 1000 1010
>>XP_016868749 (OMIM: 614440) PREDICTED: PH and SEC7 dom (1046 aa)
initn: 1923 init1: 981 opt: 1919 Z-score: 925.8 bits: 182.9 E(85289): 7.9e-45
Smith-Waterman score: 1970; 48.5% identity (71.2% similar) in 718 aa overlap (331-1023:367-1044)
310 320 330 340 350
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDED-DDEAGG
:. ::: : ... ::. .::.
XP_016 SKVPRHLISSAGLCNSSSLTENVWDESWKAPSERPGTSSG---TFSPVRLDESGEDEVFL
340 350 360 370 380 390
360 370 380 390 400 410
pF1KA2 EEDVDDEVFEASEGARPGSRMP-----LKSPVPFLPGTSPSADGPDSFSCVFEAILESHR
.:. ... .. . : :. .:. . : . . :. : .: ::.::..
XP_016 QEN-KQHLEKTPKPERDRERISEQEEHVKGEDEDILGPGYTEDSTDVYSSQFETILDN--
400 410 420 430 440 450
420 430 440 450 460
pF1KA2 AKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSG-----
. : : :::.: : : . .:.::.: : . . : : ::
XP_016 --TSLYYSAESLETLYSE-P--DSYFSFEMPLTPMIQQRIKEGGQFL---ERTSGGGHQD
460 470 480 490 500
470 480 490 500 510 520
pF1KA2 -TSSAADGPWTQRGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAP----LGSEPPLSQ
: .::: .. : . .. : . : ::. ..: ::. ..
XP_016 ILSVSADGGIVM-GYS------SGVTNGLNDAS-----DSIYTKGTPEIAFWGSNAGVKT
510 520 530 540 550
530 540 550 560 570 580
pF1KA2 LVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNN
.. ::. ::: : . ..:::: ....:::.:::::::.:: :...:::.::::::
XP_016 TRLEAHSEMGSTEILEKETPENLSNGTSSNVEAAKRLAKRLYQLDRFKRSDVAKHLGKNN
560 570 580 590 600 610
590 600 610 620 630 640
pF1KA2 DFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEAL
.:::::: :::::: ::::::::.:: :.: ..:.:::::::::: :::.::: :::...
XP_016 EFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTI
620 630 640 650 660 670
650 660 670 680 690 700
pF1KA2 SSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIK
.:.::.: ::::.::::::::::::::.::: .::.::.:.:.: :: ..::::::.:::
XP_016 ASQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSIK
680 690 700 710 720 730
710 720 730 740 750
pF1KA2 NEKLQWAIDEEELRRSLSELADP-----NPKVIKRISGGSGSGSSPFLDLTPEPGAAVYK
::::.::.:.:: ..: :: .. .::.:.:: :: ..::::. .:.:::::
XP_016 NEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISRI----GSTTNPFLDIPHDPNAAVYK
740 750 760 770 780
760 770 780 790 800 810
pF1KA2 HGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISI
: :.::.::: : .::::::::::.:...::: .:::::.:::: ::::: .::::.:.
XP_016 SGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSV
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA2 HHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAA
:::::..:.:: :.:.:: :.::::::.:::. : :.::.::..:: :::.:::::::::
XP_016 HHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAA
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA2 VSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQR
..:::::::::::...:.::::::...::.::: ...:: :::. :: ..:...: .
XP_016 IGSQKKFSRPLLPATTTKLSQEEQLKSHESKLKQITTELAEHRSYPPDKKVKAKDVDEYK
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA2 QKEAYLEFEKSRYSTYAALLRVKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPK
:. ::::::.:: :... :: :..:: :.. : :: :::::::.:
XP_016 LKDHYLEFEKTRYEMYVSI----LKEGGKEL------LSNDESEAAGLKKSHSSPSLNPD
970 980 990 1000 1010
1000 1010 1020
pF1KA2 PSS-QPRAQRHSSE---PRPGAGSGRRKP
: ...:. :: :: . : ..:
XP_016 TSPITAKVKRNVSERKDHRPETPSIKQKVT
1020 1030 1040
>>NP_056125 (OMIM: 614440) PH and SEC7 domain-containing (1047 aa)
initn: 1923 init1: 981 opt: 1919 Z-score: 925.8 bits: 182.9 E(85289): 7.9e-45
Smith-Waterman score: 1970; 48.5% identity (71.2% similar) in 718 aa overlap (331-1023:368-1045)
310 320 330 340 350
pF1KA2 IDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDED-DDEAGG
:. ::: : ... ::. .::.
NP_056 SKVPRHLISSAGLCNSSSLTENVWDESWKAPSERPGTSSG---TFSPVRLDESGEDEVFL
340 350 360 370 380 390
360 370 380 390 400 410
pF1KA2 EEDVDDEVFEASEGARPGSRMP-----LKSPVPFLPGTSPSADGPDSFSCVFEAILESHR
.:. ... .. . : :. .:. . : . . :. : .: ::.::..
NP_056 QEN-KQHLEKTPKPERDRERISEQEEHVKGEDEDILGPGYTEDSTDVYSSQFETILDN--
400 410 420 430 440 450
420 430 440 450 460
pF1KA2 AKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSG-----
. : : :::.: : : . .:.::.: : . . : : ::
NP_056 --TSLYYSAESLETLYSE-P--DSYFSFEMPLTPMIQQRIKEGGQFL---ERTSGGGHQD
460 470 480 490 500
470 480 490 500 510 520
pF1KA2 -TSSAADGPWTQRGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAP----LGSEPPLSQ
: .::: .. : . .. : . : ::. ..: ::. ..
NP_056 ILSVSADGGIVM-GYS------SGVTNGLNDAS-----DSIYTKGTPEIAFWGSNAGVKT
510 520 530 540 550
530 540 550 560 570 580
pF1KA2 LVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNN
.. ::. ::: : . ..:::: ....:::.:::::::.:: :...:::.::::::
NP_056 TRLEAHSEMGSTEILEKETPENLSNGTSSNVEAAKRLAKRLYQLDRFKRSDVAKHLGKNN
560 570 580 590 600 610
590 600 610 620 630 640
pF1KA2 DFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEAL
.:::::: :::::: ::::::::.:: :.: ..:.:::::::::: :::.::: :::...
NP_056 EFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTI
620 630 640 650 660 670
650 660 670 680 690 700
pF1KA2 SSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIK
.:.::.: ::::.::::::::::::::.::: .::.::.:.:.: :: ..::::::.:::
NP_056 ASQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSIK
680 690 700 710 720 730
710 720 730 740 750
pF1KA2 NEKLQWAIDEEELRRSLSELADP-----NPKVIKRISGGSGSGSSPFLDLTPEPGAAVYK
::::.::.:.:: ..: :: .. .::.:.:: :: ..::::. .:.:::::
NP_056 NEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISRI----GSTTNPFLDIPHDPNAAVYK
740 750 760 770 780
760 770 780 790 800 810
pF1KA2 HGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISI
: :.::.::: : .::::::::::.:...::: .:::::.:::: ::::: .::::.:.
NP_056 SGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSV
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA2 HHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAA
:::::..:.:: :.:.:: :.::::::.:::. : :.::.::..:: :::.:::::::::
NP_056 HHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAA
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA2 VSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQR
..:::::::::::...:.::::::...::.::: ...:: :::. :: ..:...: .
NP_056 IGSQKKFSRPLLPATTTKLSQEEQLKSHESKLKQITTELAEHRSYPPDKKVKAKDVDEYK
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA2 QKEAYLEFEKSRYSTYAALLRVKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPK
:. ::::::.:: :... :: :..:: :.. : :: :::::::.:
NP_056 LKDHYLEFEKTRYEMYVSI----LKEGGKEL------LSNDESEAAGLKKSHSSPSLNPD
970 980 990 1000 1010
1000 1010 1020
pF1KA2 PSS-QPRAQRHSSE---PRPGAGSGRRKP
: ...:. :: :: . : ..:
NP_056 TSPITAKVKRNVSERKDHRPETPSIKQKVT
1020 1030 1040
1024 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:57:52 2016 done: Fri Nov 4 01:57:54 2016
Total Scan time: 15.000 Total Display time: 0.340
Function used was FASTA [36.3.4 Apr, 2011]