Result of FASTA (ccds) for
pFN21AA1296
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1296, 781 aa
1>>>pF1KA1296 781 - 781 aa - 781 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2541+/-0.0011; mu= 2.5604+/- 0.066
mean_var=226.0397+/-46.477, 0's: 0 Z-trim(110.2): 85 B-trim: 9 in 2/52
Lambda= 0.085306
statistics sampled from 11391 (11462) to 11391 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.352), width: 16
Scan time: 4.590
The best scores are: opt bits E(32554)
CCDS31253.1 SORBS1 gene_id:10580|Hs108|chr10 ( 781) 5140 646.2 5.7e-185
CCDS76327.1 SORBS1 gene_id:10580|Hs108|chr10 (1004) 2697 345.7 2.3e-94
CCDS76326.1 SORBS1 gene_id:10580|Hs108|chr10 ( 811) 2674 342.8 1.4e-93
CCDS31252.1 SORBS1 gene_id:10580|Hs108|chr10 ( 684) 2457 316.0 1.3e-85
CCDS31256.1 SORBS1 gene_id:10580|Hs108|chr10 ( 905) 2253 291.0 5.9e-78
CCDS7442.1 SORBS1 gene_id:10580|Hs108|chr10 ( 816) 2233 288.5 3e-77
CCDS31254.1 SORBS1 gene_id:10580|Hs108|chr10 (1151) 2142 277.4 9.2e-74
CCDS31255.1 SORBS1 gene_id:10580|Hs108|chr10 (1292) 2141 277.3 1.1e-73
CCDS73169.1 SORBS1 gene_id:10580|Hs108|chr10 (1266) 2135 276.6 1.8e-73
CCDS43289.2 SORBS2 gene_id:8470|Hs108|chr4 ( 666) 1273 170.3 9.3e-42
CCDS47175.1 SORBS2 gene_id:8470|Hs108|chr4 ( 824) 1069 145.2 4e-34
CCDS47174.1 SORBS2 gene_id:8470|Hs108|chr4 ( 731) 1039 141.5 4.7e-33
CCDS54825.1 SORBS2 gene_id:8470|Hs108|chr4 ( 661) 977 133.8 8.6e-31
CCDS47173.1 SORBS2 gene_id:8470|Hs108|chr4 ( 644) 976 133.7 9.2e-31
CCDS47176.1 SORBS2 gene_id:8470|Hs108|chr4 (1004) 976 133.8 1.3e-30
CCDS3845.1 SORBS2 gene_id:8470|Hs108|chr4 (1100) 976 133.9 1.4e-30
CCDS59482.1 SORBS2 gene_id:8470|Hs108|chr4 (1200) 976 133.9 1.5e-30
CCDS47824.1 SORBS3 gene_id:10174|Hs108|chr8 ( 329) 651 93.5 5.9e-19
CCDS6031.1 SORBS3 gene_id:10174|Hs108|chr8 ( 671) 651 93.7 1e-18
>>CCDS31253.1 SORBS1 gene_id:10580|Hs108|chr10 (781 aa)
initn: 5140 init1: 5140 opt: 5140 Z-score: 3434.2 bits: 646.2 E(32554): 5.7e-185
Smith-Waterman score: 5140; 99.9% identity (99.9% similar) in 781 aa overlap (1-781:1-781)
10 20 30 40 50 60
pF1KA1 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 TTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 RRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFSED
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 AEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 HDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 HDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 EMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 EKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 RQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 DLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLY
730 740 750 760 770 780
pF1KA1 L
:
CCDS31 L
>>CCDS76327.1 SORBS1 gene_id:10580|Hs108|chr10 (1004 aa)
initn: 4179 init1: 2674 opt: 2697 Z-score: 1807.8 bits: 345.7 E(32554): 2.3e-94
Smith-Waterman score: 3964; 80.9% identity (82.4% similar) in 801 aa overlap (100-781:204-1004)
70 80 90 100 110 120
pF1KA1 AVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADANGNAQPS--
: :. : .. : :.: ... ::
CCDS76 LGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTPPSFS
180 190 200 210 220 230
130 140 150 160 170
pF1KA1 ------SLAAKGYRSV-HPNLPSD-KSQDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYP
: . : : .:.: . .: ::::::::::::::::::::::::::::::::
CCDS76 PPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYP
240 250 260 270 280 290
180 190 200 210 220 230
pF1KA1 STTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 STTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDD
300 310 320 330 340 350
240 250 260 270 280
pF1KA1 SRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRD--------------
::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 SRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDTPEENPYFPTYKFP
360 370 380 390 400 410
290 300 310 320 330
pF1KA1 -----------DDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPAR
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ELPEIQQTSEDDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPAR
420 430 440 450 460 470
340 350 360 370 380
pF1KA1 SSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMS-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 SSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLK
480 490 500 510 520 530
pF1KA1 ------------------------------------------------------------
CCDS76 NEPWYKFFSELEFGKPPPKKIWDYTPGDCSILPREDRKTNLDKDLSLCQTELEADLEKME
540 550 560 570 580 590
390 400 410 420 430
pF1KA1 -------------SAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYK
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 TLNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYK
600 610 620 630 640 650
440 450 460 470 480 490
pF1KA1 SVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 SVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLAD
660 670 680 690 700 710
500 510 520 530 540 550
pF1KA1 QRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 QRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFD
720 730 740 750 760 770
560 570 580 590 600 610
pF1KA1 FKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 FKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTP
780 790 800 810 820 830
620 630 640 650 660 670
pF1KA1 VQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 VQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYV
840 850 860 870 880 890
680 690 700 710 720 730
pF1KA1 DVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 DVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYS
900 910 920 930 940 950
740 750 760 770 780
pF1KA1 YIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 YIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
960 970 980 990 1000
>--
initn: 913 init1: 643 opt: 884 Z-score: 601.9 bits: 122.5 E(32554): 3.3e-27
Smith-Waterman score: 884; 76.3% identity (80.9% similar) in 194 aa overlap (1-188:1-183)
10 20 30 40 50 60
pF1KA1 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
::::::::::::::::::::::::::::::::::::::: :::::::::::
CCDS76 LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKP---------DEWRLSSSADA
70 80 90 100 110
130 140 150 160 170
pF1KA1 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSS------PLLNEVSSSLIGTDSQAFPSVSKP
::::::::::::::::::::::::::::.. : . : :..:: .. :
CCDS76 NGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KA1 SSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEK
. : . :::
CCDS76 TPLGPLGCV--PTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTP
180 190 200 210 220
>>CCDS76326.1 SORBS1 gene_id:10580|Hs108|chr10 (811 aa)
initn: 2832 init1: 2674 opt: 2674 Z-score: 1793.8 bits: 342.8 E(32554): 1.4e-93
Smith-Waterman score: 4742; 88.7% identity (88.7% similar) in 843 aa overlap (1-781:1-811)
10 20 30 40 50 60
pF1KA1 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
::::::::::::::::::::::::: :::
CCDS76 MSSECDGGSKAVMNGLAPGSNGQDK--------------------------------DMD
10 20
70 80 90 100 110 120
pF1KA1 PTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
30 40 50 60 70 80
130 140 150 160 170 180
pF1KA1 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPS
90 100 110 120 130 140
190 200 210 220 230 240
pF1KA1 TTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 TTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDS
150 160 170 180 190 200
250 260 270 280 290 300
pF1KA1 RRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 RRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFSED
210 220 230 240 250 260
310 320 330 340 350 360
pF1KA1 TKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 TKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYR
270 280 290 300 310 320
370 380
pF1KA1 AEPKSIYEYQPGKSSVLTNEKMS-------------------------------------
:::::::::::::::::::::::
CCDS76 AEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGKPTNLDKDLSLC
330 340 350 360 370 380
390 400 410
pF1KA1 -------------------------SAISPTPEISSETPGYIYSSNFHAVKRESDGAPGD
:::::::::::::::::::::::::::::::::::
CCDS76 QTELEADLEKMETLNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGD
390 400 410 420 430 440
420 430 440 450 460 470
pF1KA1 LTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIR
450 460 470 480 490 500
480 490 500 510 520 530
pF1KA1 RRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 RRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKS
510 520 530 540 550 560
540 550 560 570 580 590
pF1KA1 GSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 GSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLP
570 580 590 600 610 620
600 610 620 630 640 650
pF1KA1 PAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 PAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPG
630 640 650 660 670 680
660 670 680 690 700 710
pF1KA1 TSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 TSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQT
690 700 710 720 730 740
720 730 740 750 760 770
pF1KA1 SQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 SQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKP
750 760 770 780 790 800
780
pF1KA1 LYL
:::
CCDS76 LYL
810
>>CCDS31252.1 SORBS1 gene_id:10580|Hs108|chr10 (684 aa)
initn: 2754 init1: 2450 opt: 2457 Z-score: 1650.5 bits: 316.0 E(32554): 1.3e-85
Smith-Waterman score: 4303; 87.5% identity (87.5% similar) in 781 aa overlap (1-781:1-684)
10 20 30 40 50 60
pF1KA1 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
::::::::::::::::::::::::: :::
CCDS31 MSSECDGGSKAVMNGLAPGSNGQDK--------------------------------DMD
10 20
70 80 90 100 110 120
pF1KA1 PTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
::::::::::::::::::::::::::::::::::::::: :::::::::::
CCDS31 LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKP---------DEWRLSSSADA
30 40 50 60 70
130 140 150 160 170 180
pF1KA1 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPS
80 90 100 110 120 130
190 200 210 220 230 240
pF1KA1 TTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDS
140 150 160 170 180 190
250 260 270 280 290 300
pF1KA1 RRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFSED
200 210 220 230 240 250
310 320 330 340 350 360
pF1KA1 TKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYR
260 270 280 290 300 310
370 380 390 400 410 420
pF1KA1 AEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLT
320 330 340 350 360 370
430 440 450 460 470 480
pF1KA1 SLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRR
380 390 400 410 420 430
490 500 510 520 530 540
pF1KA1 HDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGS
:::::
CCDS31 HDDKE-------------------------------------------------------
440
550 560 570 580 590 600
pF1KA1 EMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 -MRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPA
450 460 470 480 490 500
610 620 630 640 650 660
pF1KA1 EKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTS
510 520 530 540 550 560
670 680 690 700 710 720
pF1KA1 RQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQ
570 580 590 600 610 620
730 740 750 760 770 780
pF1KA1 DLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLY
630 640 650 660 670 680
pF1KA1 L
:
CCDS31 L
>>CCDS31256.1 SORBS1 gene_id:10580|Hs108|chr10 (905 aa)
initn: 3595 init1: 2125 opt: 2253 Z-score: 1513.1 bits: 291.0 E(32554): 5.9e-78
Smith-Waterman score: 4410; 85.1% identity (85.1% similar) in 833 aa overlap (73-781:73-905)
50 60 70 80 90 100
pF1KA1 PVKTVKNASGLVLPTDMDPTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGL
::::::::::::::::::::::::::::::
CCDS31 PVKTVKNASGLVLPTDMDLTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGL
50 60 70 80 90 100
110 120 130 140
pF1KA1 EPEPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSDKSQ---------------
:::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EPEPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSDKSQRWPHHSQPARASGSF
110 120 130 140 150 160
150 160
pF1KA1 ---------------------------------------DSSPLLNEVSSSLIGTDSQAF
:::::::::::::::::::::
CCDS31 APISQTPPSFSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAF
170 180 190 200 210 220
170 180 190 200 210 220
pF1KA1 PSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 PSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSP
230 240 250 260 270 280
230 240 250 260 270 280
pF1KA1 GKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDS
290 300 310 320 330 340
290 300 310 320 330 340
pF1KA1 DLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWE
350 360 370 380 390 400
350 360 370 380
pF1KA1 PPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMS-------------------------
:::::::::::::::::::::::::::::::::::
CCDS31 PPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFG
410 420 430 440 450 460
390 400 410
pF1KA1 -------------------------SAISPTPEISSETPGYIYSSNFHAVKRESDGAPGD
:::::::::::::::::::::::::::::::::::
CCDS31 KPPPKKIWDYTPGDCSILPREDRKSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGD
470 480 490 500 510 520
420 430 440 450 460 470
pF1KA1 LTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIR
530 540 550 560 570 580
480 490 500 510 520 530
pF1KA1 RRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKS
590 600 610 620 630 640
540 550 560 570 580 590
pF1KA1 GSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLP
650 660 670 680 690 700
600 610 620 630 640 650
pF1KA1 PAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 PAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPG
710 720 730 740 750 760
660 670 680 690 700
pF1KA1 TSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQ----------------
::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQLSHHSLRAGPDLTESE
770 780 790 800 810 820
710 720 730 740 750
pF1KA1 ----QPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KSYVQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWF
830 840 850 860 870 880
760 770 780
pF1KA1 VGTSRRTKQFGTFPGNYVKPLYL
:::::::::::::::::::::::
CCDS31 VGTSRRTKQFGTFPGNYVKPLYL
890 900
>>CCDS7442.1 SORBS1 gene_id:10580|Hs108|chr10 (816 aa)
initn: 2499 init1: 2195 opt: 2233 Z-score: 1500.4 bits: 288.5 E(32554): 3e-77
Smith-Waterman score: 3827; 78.0% identity (78.0% similar) in 813 aa overlap (92-781:60-816)
70 80 90 100 110 120
pF1KA1 TKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADAN
::::::::::::::::::::::::::::::
CCDS74 TKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADAN
30 40 50 60 70 80
130 140
pF1KA1 GNAQPSSLAAKGYRSVHPNLPSDKSQD---------------------------------
:::::::::::::::::::::::::::
CCDS74 GNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPPT
90 100 110 120 130 140
pF1KA1 ------------------------------------------------------------
CCDS74 PLGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTPPSF
150 160 170 180 190 200
150 160 170
pF1KA1 ------------------------------SSPLLNEVSSSLIGTDSQAFPSVSKPSSAY
::::::::::::::::::::::::::::::
CCDS74 SPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAY
210 220 230 240 250 260
180 190 200 210 220 230
pF1KA1 PSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKD
270 280 290 300 310 320
240 250 260 270 280 290
pF1KA1 DSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 DSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFS
330 340 350 360 370 380
300 310 320 330 340 350
pF1KA1 EDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRK
390 400 410 420 430 440
360 370 380 390 400 410
pF1KA1 YRAEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 YRAEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGD
450 460 470 480 490 500
420 430 440 450 460 470
pF1KA1 LTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIR
510 520 530 540 550 560
480 490 500 510 520 530
pF1KA1 RRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKS
:::::::
CCDS74 RRHDDKE-----------------------------------------------------
570
540 550 560 570 580 590
pF1KA1 GSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ---MRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLP
580 590 600 610 620 630
600 610 620 630 640 650
pF1KA1 PAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPG
640 650 660 670 680 690
660 670 680 690 700 710
pF1KA1 TSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQT
700 710 720 730 740 750
720 730 740 750 760 770
pF1KA1 SQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKP
760 770 780 790 800 810
780
pF1KA1 LYL
:::
CCDS74 LYL
>>CCDS31254.1 SORBS1 gene_id:10580|Hs108|chr10 (1151 aa)
initn: 3071 init1: 2125 opt: 2142 Z-score: 1437.8 bits: 277.4 E(32554): 9.2e-74
Smith-Waterman score: 3329; 71.8% identity (74.9% similar) in 797 aa overlap (135-774:257-1047)
110 120 130 140 150 160
pF1KA1 EPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSD-KSQDSSPLLNEVSSSLIGT
: .:.: . .: ::::::::::::::::
CCDS31 ASGSFAPISQTPPSFSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGT
230 240 250 260 270 280
170 180 190 200 210 220
pF1KA1 DSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQE
290 300 310 320 330 340
230 240 250 260 270 280
pF1KA1 KPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLN
350 360 370 380 390 400
pF1KA1 RD----------------------------------------------------------
::
CCDS31 RDTPEENPYFPTYKFPELPEIQQTSEETKSCSVMSPRLECSGTVIAHCSLKLLDSSNPPT
410 420 430 440 450 460
290 300 310 320 330
pF1KA1 ----------DDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARS
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SASQVAGTADDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARS
470 480 490 500 510 520
340 350 360 370 380
pF1KA1 SSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMS------------
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKN
530 540 550 560 570 580
pF1KA1 ------------------------------------------------------------
CCDS31 EPWYKFFSELEFGKPPPKKIWDYTPGDCSILPREDRKTNLDKDLSLCQTELEADLEKMET
590 600 610 620 630 640
390 400 410 420 430
pF1KA1 ------------SAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKS
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKS
650 660 670 680 690 700
440 450 460 470 480 490
pF1KA1 VLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQ
710 720 730 740 750 760
500 510 520 530 540 550
pF1KA1 RRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDF
770 780 790 800 810 820
560 570 580 590 600 610
pF1KA1 KAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPV
830 840 850 860 870 880
620 630 640 650 660 670
pF1KA1 QVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVD
890 900 910 920 930 940
680 690 700 710 720 730
pF1KA1 VIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSY
::::::::::::::::::::::::::::::: : .. ... . . .
CCDS31 VIKRPLVKNPVDYMDLPFSSSPSRSATASPQ-PWREESGQYERKAERGAGERGPGG----
950 960 970 980 990 1000
740 750 760 770 780
pF1KA1 IPQNDDELELRDGDIVDVM---EKCDDGWFVGTSRRTKQFGT-FPGNYVKPLYL
:. . . :. .:.: . .. .: :: : .:. :::.
CCDS31 -PKISKKSCLKPSDVVRCLSTEQRLSDLNTPEESRPGKPLGSAFPGSEAEQTERHRGGEQ
1010 1020 1030 1040 1050 1060
CCDS31 AGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVM
1070 1080 1090 1100 1110 1120
>--
initn: 978 init1: 960 opt: 972 Z-score: 659.6 bits: 133.4 E(32554): 2e-30
Smith-Waterman score: 972; 80.9% identity (85.6% similar) in 194 aa overlap (1-188:1-192)
10 20 30 40 50 60
pF1KA1 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
70 80 90 100 110 120
130 140 150 160 170
pF1KA1 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSS------PLLNEVSSSLIGTDSQAFPSVSKP
::::::::::::::::::::::::::::.. : . : :..:: .. :
CCDS31 NGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 SSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEK
. : . :::
CCDS31 TPLGPLGCV--PTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTP
190 200 210 220 230
>--
initn: 570 init1: 556 opt: 556 Z-score: 382.9 bits: 82.2 E(32554): 5.3e-15
Smith-Waterman score: 556; 100.0% identity (100.0% similar) in 80 aa overlap (702-781:1072-1151)
680 690 700 710 720 730
pF1KA1 VIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSY
::::::::::::::::::::::::::::::
CCDS31 SAFPGSEAEQTERHRGGEQAGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSY
1050 1060 1070 1080 1090 1100
740 750 760 770 780
pF1KA1 IPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 IPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
1110 1120 1130 1140 1150
>>CCDS31255.1 SORBS1 gene_id:10580|Hs108|chr10 (1292 aa)
initn: 3071 init1: 2125 opt: 2141 Z-score: 1436.4 bits: 277.3 E(32554): 1.1e-73
Smith-Waterman score: 3376; 79.0% identity (80.4% similar) in 710 aa overlap (135-713:257-965)
110 120 130 140 150 160
pF1KA1 EPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSD-KSQDSSPLLNEVSSSLIGT
: .:.: . .: ::::::::::::::::
CCDS31 ASGSFAPISQTPPSFSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGT
230 240 250 260 270 280
170 180 190 200 210 220
pF1KA1 DSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQE
290 300 310 320 330 340
230 240 250 260 270 280
pF1KA1 KPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLN
350 360 370 380 390 400
290
pF1KA1 RD----------------------------------------------DDSDLYSPRYSF
:: ::::::::::::
CCDS31 RDTPEENPYFPTYKFPELPEIQQTSEEDNPYTPTYQFPASTPSPKSEDDDSDLYSPRYSF
410 420 430 440 450 460
300 310 320 330 340 350
pF1KA1 SEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTR
470 480 490 500 510 520
360 370 380
pF1KA1 KYRAEPKSIYEYQPGKSSVLTNEKMS----------------------------------
::::::::::::::::::::::::::
CCDS31 KYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWD
530 540 550 560 570 580
390
pF1KA1 --------------------------------------------------SAISPTPEIS
::::::::::
CCDS31 YTPGDCSILPREDRKTNLDKDLSLCQTELEADLEKMETLNKAPSANVPQSSAISPTPEIS
590 600 610 620 630 640
400 410 420 430 440 450
pF1KA1 SETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSA
650 660 670 680 690 700
460 470 480 490 500 510
pF1KA1 STKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 STKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIP
710 720 730 740 750 760
520 530 540 550 560 570
pF1KA1 THHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 THHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQI
770 780 790 800 810 820
580 590 600 610 620 630
pF1KA1 DQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEM
830 840 850 860 870 880
640 650 660 670 680 690
pF1KA1 SFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSP
890 900 910 920 930 940
700 710 720 730 740 750
pF1KA1 SRSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKC
::::::::: ..... .::
CCDS31 SRSATASPQF-SSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVPGRRSLALTP
950 960 970 980 990 1000
>--
initn: 978 init1: 960 opt: 972 Z-score: 658.8 bits: 133.4 E(32554): 2.2e-30
Smith-Waterman score: 972; 80.9% identity (85.6% similar) in 194 aa overlap (1-188:1-192)
10 20 30 40 50 60
pF1KA1 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
70 80 90 100 110 120
130 140 150 160 170
pF1KA1 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSS------PLLNEVSSSLIGTDSQAFPSVSKP
::::::::::::::::::::::::::::.. : . : :..:: .. :
CCDS31 NGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 SSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEK
. : . :::
CCDS31 TPLGPLGCV--PTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTP
190 200 210 220 230
>--
initn: 618 init1: 556 opt: 556 Z-score: 382.2 bits: 82.2 E(32554): 5.8e-15
Smith-Waterman score: 556; 100.0% identity (100.0% similar) in 80 aa overlap (702-781:1213-1292)
680 690 700 710 720 730
pF1KA1 VIKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSY
::::::::::::::::::::::::::::::
CCDS31 SAFPGSEAEQTERHRGGEQAGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSY
1190 1200 1210 1220 1230 1240
740 750 760 770 780
pF1KA1 IPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 IPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
1250 1260 1270 1280 1290
>>CCDS73169.1 SORBS1 gene_id:10580|Hs108|chr10 (1266 aa)
initn: 3606 init1: 2125 opt: 2135 Z-score: 1432.5 bits: 276.6 E(32554): 1.8e-73
Smith-Waterman score: 3484; 79.3% identity (82.2% similar) in 726 aa overlap (84-713:195-919)
60 70 80 90 100 110
pF1KA1 VLPTDMDPTKICTGKGAVTLRASSSYRETPSSSPASPQE--TRQHESKPGLEPEPSSADE
..: ::: : . : :. : ..
CCDS73 YLVNTDRGQEGTARPPTPLGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQP
170 180 190 200 210 220
120 130 140 150 160
pF1KA1 WRLSSSADANGNAQPS--------SLAAKGYRSV-HPNLPSD-KSQDSSPLLNEVSSSLI
: :.: ... :: : . : : .:.: . .: ::::::::::::::
CCDS73 ARASGSFAPISQTPPSFSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLI
230 240 250 260 270 280
170 180 190 200 210 220
pF1KA1 GTDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GTDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPT
290 300 310 320 330 340
230 240 250 260 270 280
pF1KA1 QEKPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 QEKPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHK
350 360 370 380 390 400
290 300 310 320 330 340
pF1KA1 LNRDDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LNRDDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSS
410 420 430 440 450 460
350 360 370 380
pF1KA1 SERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMS------------------
::::::::::::::::::::::::::::::::::::::::::
CCDS73 SERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKF
470 480 490 500 510 520
pF1KA1 ------------------------------------------------------------
CCDS73 FSELEFGKPPPKKIWDYTPGDCSILPREDRKTNLDKDLSLCQTELEADLEKMETLNKAPS
530 540 550 560 570 580
390 400 410 420 430
pF1KA1 ------SAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKSVLEGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ANVPQSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKSVLEGGD
590 600 610 620 630 640
440 450 460 470 480 490
pF1KA1 IPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKRE
650 660 670 680 690 700
500 510 520 530 540 550
pF1KA1 QEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDFKAQTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 QEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDFKAQTLK
710 720 730 740 750 760
560 570 580 590 600 610
pF1KA1 ELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVLEYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVLEYG
770 780 790 800 810 820
620 630 640 650 660 670
pF1KA1 EAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPL
830 840 850 860 870 880
680 690 700 710 720 730
pF1KA1 VKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDD
::::::::::::::::::::::::: ..... .::
CCDS73 VKNPVDYMDLPFSSSPSRSATASPQF-SSHSKLITPAPSSLPHSRRALSPEMHAVTSEWI
890 900 910 920 930 940
740 750 760 770 780
pF1KA1 ELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
CCDS73 SLTVGVPGRRSLALTPPLPPLPEASIYNTDHLALSPRASPSLSLSLPHLSWSDRPTPRSV
950 960 970 980 990 1000
>--
initn: 960 init1: 960 opt: 972 Z-score: 659.0 bits: 133.4 E(32554): 2.2e-30
Smith-Waterman score: 972; 80.9% identity (85.6% similar) in 194 aa overlap (1-188:1-192)
10 20 30 40 50 60
pF1KA1 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 PTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
70 80 90 100 110 120
130 140 150 160 170
pF1KA1 NGNAQPSSLAAKGYRSVHPNLPSDKSQDSS------PLLNEVSSSLIGTDSQAFPSVSKP
::::::::::::::::::::::::::::.. : . : :..:: .. :
CCDS73 NGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 SSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEK
. : . :::
CCDS73 TPLGPLGCV--PTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTP
190 200 210 220 230
>--
initn: 587 init1: 549 opt: 549 Z-score: 377.6 bits: 81.4 E(32554): 1e-14
Smith-Waterman score: 549; 100.0% identity (100.0% similar) in 79 aa overlap (703-781:1188-1266)
680 690 700 710 720 730
pF1KA1 IKRPLVKNPVDYMDLPFSSSPSRSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYI
::::::::::::::::::::::::::::::
CCDS73 RKAARRGGSQLSHHSLRAGPDLTESEKSYVQPQAQQRRVTPDRSQTSQDLFSYQALYSYI
1160 1170 1180 1190 1200 1210
740 750 760 770 780
pF1KA1 PQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 PQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
1220 1230 1240 1250 1260
>>CCDS43289.2 SORBS2 gene_id:8470|Hs108|chr4 (666 aa)
initn: 1410 init1: 344 opt: 1273 Z-score: 863.1 bits: 170.3 E(32554): 9.3e-42
Smith-Waterman score: 1407; 39.8% identity (64.1% similar) in 699 aa overlap (122-779:4-666)
100 110 120 130 140 150
pF1KA1 ETRQHESKPGLEPEPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSDKSQDSSP
: . : .:::.:::.::: . .: .:
CCDS43 MNTGRDSQSPDSAKGFRSVRPNLQDKRSPTQSQ
10 20 30
160 170 180 190 200 210
pF1KA1 LLNEVSSSLIGTDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSL-SDPVSE
. . .:. . . . .:: :: . .: .::. ::. .:: : .
CCDS43 ITVNGNSGGAVSPMSYYQRPFSPS-AYSLPASLNSSIVM-QHG-------TSLDSTDTYP
40 50 60 70 80
220 230 240 250 260
pF1KA1 RRVGEQDSAPTQEKPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIP--LRNT-ER
... :.. .. : .. :::. :.:. . . .:: ::: .:.: .:
CCDS43 QHAQSLDGTTSSSIPLYRSSEEEKRVT-----VIKAPHYPGIGPVDESGIPTAIRTTVDR
90 100 110 120 130
270 280 290 300 310
pF1KA1 SKDWYKTMFKQIHKLNR-DDDSDLYSPRYSFSEDTKSP----LSVPRSKSEM------SY
:::::::::::: ... :::.:.:. :... .: : : .:.. :.
CCDS43 PKDWYKTMFKQIHMVHKPDDDTDMYNTPYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSH
140 150 160 170 180 190
320 330 340 350 360
pF1KA1 IDGEKVVKRSATLPLPA----------RSSSLKSSSERNDWEPPDKKVDTRKYRAEPKSI
:. . ..:. :.: : . .::.:..::.:::.::::::.:.::.::
CCDS43 SDNSPNAFKDASSPVPPPHVPPPVPPLRPRD-RSSTEKHDWDPPDRKVDTRKFRSEPRSI
200 210 220 230 240 250
370 380 390 400 410 420
pF1KA1 YEYQPGKSSVLTNEKMSSAISPTPEISSET-PGYIYSSNFH----AVKRESDGAPGDLTS
.::.:::::.: .:. .. :.: .:. :. : : . :... :. : . ..
CCDS43 FEYEPGKSSILQHERPTDRINPD-DIDLENEPWYKFFSELEFGRPPPKKPLDYVQDHSSG
260 270 280 290 300 310
430 440 450 460 470
pF1KA1 LENERQIYKSVLEGGDIPLQGLSGLKRPSSSAS-TKDSESPRHFIPADYLEST--EEFIR
. :: ..:.: .. .:.:: :::: ..: .. :. :: ..
CCDS43 VFNEASLYQSSID---------RSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSAS
320 330 340 350 360
480 490 500 510 520 530
pF1KA1 RRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKR-K
: . : ... : . .. .. .. . ... .. : .. .: : .
CCDS43 RTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSST-----LTDMGRSAPRER
370 380 390 400 410 420
540 550 560 570 580 590
pF1KA1 SGS---EMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYI
:. : ::.: .:::::: ::: ..::: ::: ..:::::::::::::::::: .:.
CCDS43 RGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYV
430 440 450 460 470 480
600 610 620 630 640 650
pF1KA1 ELLPPAEKAQPKKLTP-VQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYE
: : : ::::: . : .: : ::::::.:::.::.::.:.:::.:. ::..::.::::
CCDS43 EKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYE
490 500 510 520 530 540
660 670 680 690 700 710
pF1KA1 GRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMD--LPFSSSPSRSATASPQQPQAQQRRV
:.::::.::::::..::.:.:. .:. :: : .: : : .: . : ..:: : :
CCDS43 GKIPGTNRQGIFPVSYVEVVKKN-TKGAEDYPDPPIPHSYSSDRIHSLSSNKPQ---RPV
550 560 570 580 590
720 730 740 750 760 770
pF1KA1 -TPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGT
: . : . . : ::::.: :.:.::::::..:..::::::::::::::::::: :::
CCDS43 FTHENIQGGGEPF--QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGT
600 610 620 630 640 650
780
pF1KA1 FPGNYVKPLYL
::::::: :
CCDS43 FPGNYVKRL
660
781 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:28:37 2016 done: Fri Nov 4 01:28:37 2016
Total Scan time: 4.590 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]