Result of FASTA (omim) for
pFN21AB9098
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9098, 1257 aa
1>>>pF1KB9098 1257 - 1257 aa - 1257 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3539+/-0.000453; mu= 12.7075+/- 0.028
mean_var=151.0692+/-30.006, 0's: 0 Z-trim(113.4): 394 B-trim: 27 in 1/58
Lambda= 0.104349
statistics sampled from 22255 (22703) to 22255 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.266), width: 16
Scan time: 14.040
The best scores are: opt bits E(85289)
NP_001139120 (OMIM: 606600) ras-specific guanine n (1257) 8195 1247.2 0
XP_016877945 (OMIM: 606600) PREDICTED: ras-specifi (1260) 8179 1244.8 0
XP_016877947 (OMIM: 606600) PREDICTED: ras-specifi (1245) 7573 1153.6 0
XP_016877948 (OMIM: 606600) PREDICTED: ras-specifi (1185) 7557 1151.2 0
XP_016877946 (OMIM: 606600) PREDICTED: ras-specifi (1248) 7557 1151.2 0
XP_016877944 (OMIM: 606600) PREDICTED: ras-specifi (1270) 4195 645.1 9e-184
XP_011520169 (OMIM: 606600) PREDICTED: ras-specifi (1198) 4025 619.4 4.4e-176
XP_011520168 (OMIM: 606600) PREDICTED: ras-specifi (1261) 4025 619.5 4.5e-176
NP_002882 (OMIM: 606600) ras-specific guanine nucl (1273) 4025 619.5 4.6e-176
XP_016865172 (OMIM: 606614) PREDICTED: ras-specifi ( 897) 3747 577.5 1.4e-163
XP_005248622 (OMIM: 606614) PREDICTED: ras-specifi ( 937) 3747 577.5 1.4e-163
NP_008840 (OMIM: 606614) ras-specific guanine nucl (1237) 3747 577.6 1.8e-163
XP_016865171 (OMIM: 606614) PREDICTED: ras-specifi (1142) 3376 521.7 1.1e-146
NP_722522 (OMIM: 606600) ras-specific guanine nucl ( 489) 3175 491.2 7.3e-138
XP_016870126 (OMIM: 600303) PREDICTED: rap guanine (1225) 534 93.9 7.1e-18
XP_011531368 (OMIM: 135300,182530,610733) PREDICTE ( 978) 531 93.4 8.2e-18
XP_005272248 (OMIM: 600303) PREDICTED: rap guanine (1226) 531 93.5 9.7e-18
XP_006717135 (OMIM: 600303) PREDICTED: rap guanine (1232) 531 93.5 9.8e-18
XP_016870125 (OMIM: 600303) PREDICTED: rap guanine (1233) 531 93.5 9.8e-18
XP_016870124 (OMIM: 600303) PREDICTED: rap guanine (1241) 531 93.5 9.8e-18
XP_016870123 (OMIM: 600303) PREDICTED: rap guanine (1241) 531 93.5 9.8e-18
XP_016870122 (OMIM: 600303) PREDICTED: rap guanine (1247) 531 93.5 9.8e-18
XP_011516875 (OMIM: 600303) PREDICTED: rap guanine (1255) 531 93.5 9.9e-18
XP_005272243 (OMIM: 600303) PREDICTED: rap guanine (1264) 531 93.5 9.9e-18
XP_006717130 (OMIM: 600303) PREDICTED: rap guanine (1270) 531 93.5 1e-17
XP_011516874 (OMIM: 600303) PREDICTED: rap guanine (1272) 531 93.5 1e-17
XP_011516873 (OMIM: 600303) PREDICTED: rap guanine (1273) 531 93.5 1e-17
XP_011531366 (OMIM: 135300,182530,610733) PREDICTE (1276) 531 93.5 1e-17
XP_011516872 (OMIM: 600303) PREDICTED: rap guanine (1277) 531 93.5 1e-17
XP_011516871 (OMIM: 600303) PREDICTED: rap guanine (1278) 531 93.5 1e-17
XP_005264572 (OMIM: 135300,182530,610733) PREDICTE (1318) 531 93.5 1e-17
XP_011531364 (OMIM: 135300,182530,610733) PREDICTE (1326) 531 93.5 1e-17
NP_005624 (OMIM: 135300,182530,610733) son of seve (1333) 531 93.5 1e-17
XP_016870128 (OMIM: 600303) PREDICTED: rap guanine (1192) 528 93.0 1.3e-17
XP_016870127 (OMIM: 600303) PREDICTED: rap guanine (1194) 523 92.2 2.2e-17
XP_011516878 (OMIM: 600303) PREDICTED: rap guanine (1161) 522 92.1 2.4e-17
XP_011516879 (OMIM: 600303) PREDICTED: rap guanine (1160) 521 91.9 2.6e-17
XP_011516880 (OMIM: 600303) PREDICTED: rap guanine (1139) 510 90.3 8.2e-17
NP_008870 (OMIM: 601247,616559) son of sevenless h (1332) 511 90.5 8.3e-17
XP_011516877 (OMIM: 600303) PREDICTED: rap guanine (1246) 510 90.3 8.8e-17
XP_011516876 (OMIM: 600303) PREDICTED: rap guanine (1247) 510 90.3 8.8e-17
NP_005303 (OMIM: 600303) rap guanine nucleotide ex (1077) 506 89.6 1.2e-16
NP_001291204 (OMIM: 600303) rap guanine nucleotide (1094) 506 89.6 1.2e-16
NP_941372 (OMIM: 600303) rap guanine nucleotide ex (1095) 506 89.6 1.2e-16
XP_006717137 (OMIM: 600303) PREDICTED: rap guanine (1100) 506 89.7 1.2e-16
XP_011516881 (OMIM: 600303) PREDICTED: rap guanine (1108) 506 89.7 1.2e-16
NP_001177659 (OMIM: 614444) ras-specific guanine n ( 305) 396 72.7 4.4e-12
XP_016870839 (OMIM: 614444) PREDICTED: ras-specifi ( 384) 396 72.7 5.2e-12
NP_001309253 (OMIM: 614444) ras-specific guanine n ( 514) 396 72.8 6.5e-12
XP_011517538 (OMIM: 614444) PREDICTED: ras-specifi ( 515) 396 72.8 6.6e-12
>>NP_001139120 (OMIM: 606600) ras-specific guanine nucle (1257 aa)
initn: 8195 init1: 8195 opt: 8195 Z-score: 6674.8 bits: 1247.2 E(85289): 0
Smith-Waterman score: 8195; 100.0% identity (100.0% similar) in 1257 aa overlap (1-1257:1-1257)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 FLHSYRVFTTAIVVLDKLITIYKKPISAIPARSLELLFASGQNNKLLYGEPPKSPRATRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLHSYRVFTTAIVVLDKLITIYKKPISAIPARSLELLFASGQNNKLLYGEPPKSPRATRK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 FSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFSKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFSKAT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 LDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGDTET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGDTET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 SPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGANEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGANEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 TPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETNDELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETNDELK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 CKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEPFEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEPFEN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 HSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 IIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 ALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250
pF1KB9 KMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT
1210 1220 1230 1240 1250
>>XP_016877945 (OMIM: 606600) PREDICTED: ras-specific gu (1260 aa)
initn: 4535 init1: 4535 opt: 8179 Z-score: 6661.7 bits: 1244.8 E(85289): 0
Smith-Waterman score: 8179; 99.8% identity (99.8% similar) in 1260 aa overlap (1-1257:1-1260)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
610 620 630 640 650 660
670 680 690 700 710
pF1KB9 FLHSYRVFTTAIVVLDKLITIYKKPISAIPAR---SLELLFASGQNNKLLYGEPPKSPRA
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 FLHSYRVFTTAIVVLDKLITIYKKPISAIPARWLRSLELLFASGQNNKLLYGEPPKSPRA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB9 TRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFS
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB9 KATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGD
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB9 TETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB9 NEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETND
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB9 ELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEP
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB9 FENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB9 ASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSK
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB9 QTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLV
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KB9 NFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT
1210 1220 1230 1240 1250 1260
>>XP_016877947 (OMIM: 606600) PREDICTED: ras-specific gu (1245 aa)
initn: 7573 init1: 7573 opt: 7573 Z-score: 6168.7 bits: 1153.6 E(85289): 0
Smith-Waterman score: 7573; 100.0% identity (100.0% similar) in 1164 aa overlap (1-1164:1-1164)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 FLHSYRVFTTAIVVLDKLITIYKKPISAIPARSLELLFASGQNNKLLYGEPPKSPRATRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLHSYRVFTTAIVVLDKLITIYKKPISAIPARSLELLFASGQNNKLLYGEPPKSPRATRK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 FSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFSKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFSKAT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 LDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGDTET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGDTET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 SPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGANEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGANEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 TPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETNDELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETNDELK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 CKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEPFEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEPFEN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 HSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 IIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 ALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFS
::::::::::::::::::::::::
XP_016 ALIDKLQKLVSSEGRFKNLREALKKQMLHPSVLSSRLSSAWAPESPCGLCLWGAAPSVHS
1150 1160 1170 1180 1190 1200
>>XP_016877948 (OMIM: 606600) PREDICTED: ras-specific gu (1185 aa)
initn: 4535 init1: 4535 opt: 7557 Z-score: 6156.0 bits: 1151.2 E(85289): 0
Smith-Waterman score: 7557; 99.7% identity (99.7% similar) in 1167 aa overlap (1-1164:1-1167)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
610 620 630 640 650 660
670 680 690 700 710
pF1KB9 FLHSYRVFTTAIVVLDKLITIYKKPISAIPAR---SLELLFASGQNNKLLYGEPPKSPRA
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 FLHSYRVFTTAIVVLDKLITIYKKPISAIPARWLRSLELLFASGQNNKLLYGEPPKSPRA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB9 TRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFS
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB9 KATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGD
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB9 TETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB9 NEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETND
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB9 ELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEP
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB9 FENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB9 ASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSK
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB9 QTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLV
:::::::::::::::::::::::::::
XP_016 QTKALIDKLQKLVSSEGRFKNLREALKKYPILSERFASFNKLPTK
1150 1160 1170 1180
>>XP_016877946 (OMIM: 606600) PREDICTED: ras-specific gu (1248 aa)
initn: 4535 init1: 4535 opt: 7557 Z-score: 6155.7 bits: 1151.2 E(85289): 0
Smith-Waterman score: 7557; 99.7% identity (99.7% similar) in 1167 aa overlap (1-1164:1-1167)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNT
610 620 630 640 650 660
670 680 690 700 710
pF1KB9 FLHSYRVFTTAIVVLDKLITIYKKPISAIPAR---SLELLFASGQNNKLLYGEPPKSPRA
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 FLHSYRVFTTAIVVLDKLITIYKKPISAIPARWLRSLELLFASGQNNKLLYGEPPKSPRA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB9 TRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFS
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB9 KATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESDIDQNQSDDGD
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB9 TETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB9 NEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETND
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB9 ELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEP
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB9 FENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB9 ASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSK
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB9 QTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLV
:::::::::::::::::::::::::::
XP_016 QTKALIDKLQKLVSSEGRFKNLREALKKQMLHPSVLSSRLSSAWAPESPCGLCLWGAAPS
1150 1160 1170 1180 1190 1200
>>XP_016877944 (OMIM: 606600) PREDICTED: ras-specific gu (1270 aa)
initn: 4195 init1: 4195 opt: 4195 Z-score: 3420.3 bits: 645.1 E(85289): 9e-184
Smith-Waterman score: 8159; 99.0% identity (99.0% similar) in 1270 aa overlap (1-1257:1-1270)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640
pF1KB9 KVTVPQMIK-------------SDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL
::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 KVTVPQMIKRTREGTREAEMSRSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB9 TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPARSLELLFASGQNNKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPARSLELLFASGQNNKLL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB9 YGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB9 SMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMREESD
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB9 IDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB9 SAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVS
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB9 KHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEIT
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB9 QMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTT
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KB9 KHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFR
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KB9 LKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEG
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KB9 TPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYES
1210 1220 1230 1240 1250 1260
1250
pF1KB9 SLRIEPKLPT
::::::::::
XP_016 SLRIEPKLPT
1270
>>XP_011520169 (OMIM: 606600) PREDICTED: ras-specific gu (1198 aa)
initn: 7043 init1: 4009 opt: 4025 Z-score: 3282.3 bits: 619.4 E(85289): 4.4e-176
Smith-Waterman score: 7521; 98.6% identity (98.6% similar) in 1180 aa overlap (1-1164:1-1180)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640
pF1KB9 KVTVPQMIK-------------SDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL
::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 KVTVPQMIKRTREGTREAEMSRSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB9 TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPAR---SLELLFASGQNN
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPARWLRSLELLFASGQNN
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB9 KLLYGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLLYGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSN
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB9 GYTSMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYTSMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMRE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB9 ESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSAL
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB9 SAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRH
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB9 WVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLE
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB9 EITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KB9 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KB9 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFI
::::::::::::::::::::::::::::::::::::::::
XP_011 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKKYPILSERFASFNKLPTK
1150 1160 1170 1180 1190
1190 1200 1210 1220 1230 1240
pF1KB9 EEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESL
>>XP_011520168 (OMIM: 606600) PREDICTED: ras-specific gu (1261 aa)
initn: 7043 init1: 4009 opt: 4025 Z-score: 3282.0 bits: 619.5 E(85289): 4.5e-176
Smith-Waterman score: 7521; 98.6% identity (98.6% similar) in 1180 aa overlap (1-1164:1-1180)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640
pF1KB9 KVTVPQMIK-------------SDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL
::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 KVTVPQMIKRTREGTREAEMSRSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB9 TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPAR---SLELLFASGQNN
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPARWLRSLELLFASGQNN
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB9 KLLYGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLLYGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSN
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB9 GYTSMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYTSMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMRE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB9 ESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSAL
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB9 SAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRH
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB9 WVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLE
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB9 EITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KB9 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KB9 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFI
::::::::::::::::::::::::::::::::::::::::
XP_011 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKKQMLHPSVLSSRLSSAWAPE
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KB9 EEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESL
XP_011 SPCGLCLWGAAPSVHSPTCPSVRPRGTTPSTSSHGWLPRLPPPPPLPPLPLGPPILSESP
1210 1220 1230 1240 1250 1260
>>NP_002882 (OMIM: 606600) ras-specific guanine nucleoti (1273 aa)
initn: 7665 init1: 4009 opt: 4025 Z-score: 3282.0 bits: 619.5 E(85289): 4.6e-176
Smith-Waterman score: 8143; 98.7% identity (98.7% similar) in 1273 aa overlap (1-1257:1-1273)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITRGRLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLEEPESTEEEAKGSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNAFEENS
550 560 570 580 590 600
610 620 630 640
pF1KB9 KVTVPQMIK-------------SDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL
::::::::: ::::::::::::::::::::::::::::::::::::::
NP_002 KVTVPQMIKRTREGTREAEMSRSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB9 TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPAR---SLELLFASGQNN
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_002 TDLRFLSIDFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPARWLRSLELLFASGQNN
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB9 KLLYGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KLLYGEPPKSPRATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSN
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB9 GYTSMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GYTSMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPEDPSALSKQSSEVSMRE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB9 ESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSAL
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB9 SAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRH
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB9 WVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLE
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB9 EITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIM
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KB9 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSA
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KB9 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFI
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KB9 EEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESL
1210 1220 1230 1240 1250 1260
1250
pF1KB9 YESSLRIEPKLPT
:::::::::::::
NP_002 YESSLRIEPKLPT
1270
>>XP_016865172 (OMIM: 606614) PREDICTED: ras-specific gu (897 aa)
initn: 2361 init1: 1877 opt: 3747 Z-score: 3057.9 bits: 577.5 E(85289): 1.4e-163
Smith-Waterman score: 3795; 64.6% identity (83.5% similar) in 913 aa overlap (1-902:1-894)
10 20 30 40 50 60
pF1KB9 MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSS
:::..: :.::. :..::::.::..:.:::.... ..:. ::::: ::.:::::...:
XP_016 MQKSVRYNEGHALYLAFLARKEGTKRGFLSKKTAEASRWHEKWFALYQNVLFYFEGEQSC
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 RPSGLYLLEGCVCDRAPSPKPALSA----KEPLEKQHYFTVNFSHENQKALELRTEDAKD
::.:.:::::: :.:.:.: : .. .. :.::.:::: :.::.:: :::: :. .:
XP_016 RPAGMYLLEGCSCERTPAPPRAGAGQGGVRDALDKQYYFTVLFGHEGQKPLELRCEEEQD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 CDEWVAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKA
::. :: .::: . :.:.:::::.::.::::::: .:.:::.:.:: . ::::::.
XP_016 GKEWMEAIHQASYADILIEREVLMQKYIHLVQIVETEKIAANQLRHQLEDQDTEIERLKS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 EITSLLKDNERIQSTQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHAD
:: .: : .::.. :. .::: :::::::::::.::::::::::::.:::: ::::.
XP_016 EIIALNKTKERMRPYQS-NQEDEDPDIKKIKKVQSFMRGWLCRRKWKTIVQDYICSPHAE
190 200 210 220 230
240 250 260 270 280 290
pF1KB9 SMRKRNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETI
:::::::.::.:.:::.:::.::.::::.::::::::::::::::.::::::::::::::
XP_016 SMRKRNQIVFTMVEAESEYVHQLYILVNGFLRPLRMAASSKKPPISHDDVSSIFLNSETI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 MFLHQIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDF
::::.::.:::::::..::::.:::::::::::::::::::::::::::.::.:::::::
XP_016 MFLHEIFHQGLKARIANWPTLILADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNRDF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 DKLLKHYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKL
:::::.:::.: :: : ::::::::::::::::.::::::::::::::::.::..:::::
XP_016 DKLLKQYEANPACEGRMLETFLTYPMFQIPRYIITLHELLAHTPHEHVERKSLEFAKSKL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 EELSRIMHDEVSETENIRKNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEKGKITR
:::::.::::::.::::::::::::::.:::.:::::::::.::::::::: :.::...
XP_016 EELSRVMHDEVSDTENIRKNLAIERMIVEGCDILLDTSQTFIRQGSLIQVPSVERGKLSK
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB9 GRLGSLSLKKEGERQCFLFSKHLIICTRGSGGKLHLTKNG-VISLIDCTLLEEPESTEEE
::::::::::::::::::.::..::::.::::::: :.: :.:::::::.:::......
XP_016 VRLGSLSLKKEGERQCFLFTKHFLICTRSSGGKLHLLKTGGVLSLIDCTLIEEPDASDDD
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB9 AKGSGQDIDHLDFKIGVEPKDSPPFTVILVASSRQEKAAWTSDISQCVDNIRCNGLMMNA
.::::: . :::::: ::: :. :::.:.: :::::::: :::::::::::::::: .
XP_016 SKGSGQVFGHLDFKIVVEPPDAAAFTVVLLAPSRQEKAAWMSDISQCVDNIRCNGLMTIV
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB9 FEENSKVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSI
::::::::::.:::::: :. ::.:: ::::.::::: ::::::::::::::::::::::
XP_016 FEENSKVTVPHMIKSDARLHKDDTDICFSKTLNSCKVPQIRYASVERLLERLTDLRFLSI
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB9 DFLNTFLHSYRVFTTAIVVLDKLITIYKKPISAIPARSLELLFASGQNNKLLYGEPPKSP
::::::::.::.:::: ::: :: :::.:...::.:::::.::..:::. . :::
XP_016 DFLNTFLHTYRIFTTAAVVLGKLSDIYKRPFTSIPVRSLELFFATSQNNRGEHLVDGKSP
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB9 RATRKFSSPPPLSITKTSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSP
: :::::::::....:::: : :::::. :. . ::::.. : .. : .. :
XP_016 RLCRKFSSPPPLAVSRTSSPVRARKLSLTSPLNSKIGALDLTTSSSPTTTTQSPAASPPP
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB9 FS-KATLDTSKLYVSSSFTNKIPDEGDTTPEKPE-DPSALSKQSSEVSMREESDIDQ---
. . :: :. . : .. : . . ..:. : :.: . .. : . :.
XP_016 HTGQIPLDLSR---GLSSPEQSPGTVEENVDNPRVDLCNKLKRSIQKAVLESAPADRAGV
780 790 800 810 820 830
840 850 860 870 880
pF1KB9 NQSDDGDT-ETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELDNNRSALSAASA
..: .:: : :: .::.::. .. .. : .: . :: . ..: :::
XP_016 ESSPAADTTELSPCRSPSTPRHLRYRQ----P-----GG------QTADNAHCSVSPASA
840 850 860 870 880
890 900 910 920 930 940
pF1KB9 FAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKH
::::::.:..:.:
XP_016 FAIATAAAGHGSPPEP
890
1257 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:01:40 2016 done: Thu Nov 3 23:01:42 2016
Total Scan time: 14.040 Total Display time: 0.690
Function used was FASTA [36.3.4 Apr, 2011]