Result of FASTA (omim) for
pFN21AB3300
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3300, 723 aa
1>>>pF1KB3300 723 - 723 aa - 723 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.1423+/-0.000571; mu= -10.2351+/- 0.035
mean_var=581.7748+/-121.869, 0's: 0 Z-trim(119.9): 101 B-trim: 0 in 0/56
Lambda= 0.053174
statistics sampled from 34325 (34426) to 34325 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.404), width: 16
Scan time: 12.000
The best scores are: opt bits E(85289)
XP_016870772 (OMIM: 610933,614436) PREDICTED: E3 u ( 723) 4682 375.0 5.9e-103
NP_001005373 (OMIM: 610933,614436) E3 ubiquitin-pr ( 723) 4682 375.0 5.9e-103
NP_001005374 (OMIM: 610933,614436) E3 ubiquitin-pr ( 723) 4682 375.0 5.9e-103
NP_612370 (OMIM: 610933,614436) E3 ubiquitin-prote ( 723) 4682 375.0 5.9e-103
XP_006717379 (OMIM: 610933,614436) PREDICTED: E3 u ( 690) 3395 276.2 3e-73
NP_001177652 (OMIM: 610933,614436) E3 ubiquitin-pr ( 696) 3074 251.6 7.9e-66
XP_016870773 (OMIM: 610933,614436) PREDICTED: E3 u ( 460) 2961 242.7 2.5e-63
>>XP_016870772 (OMIM: 610933,614436) PREDICTED: E3 ubiqu (723 aa)
initn: 4682 init1: 4682 opt: 4682 Z-score: 1969.3 bits: 375.0 E(85289): 5.9e-103
Smith-Waterman score: 4682; 99.7% identity (100.0% similar) in 723 aa overlap (1-723:1-723)
10 20 30 40 50 60
pF1KB3 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 EEQSRLEQGLSEHQRHLDAERRRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
:::::::::::::::::.:::.::::::::::::::::::::::::::::::::::::::
XP_016 EEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
670 680 690 700 710 720
pF1KB3 HSS
:::
XP_016 HSS
>>NP_001005373 (OMIM: 610933,614436) E3 ubiquitin-protei (723 aa)
initn: 4682 init1: 4682 opt: 4682 Z-score: 1969.3 bits: 375.0 E(85289): 5.9e-103
Smith-Waterman score: 4682; 99.7% identity (100.0% similar) in 723 aa overlap (1-723:1-723)
10 20 30 40 50 60
pF1KB3 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 EEQSRLEQGLSEHQRHLDAERRRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
:::::::::::::::::.:::.::::::::::::::::::::::::::::::::::::::
NP_001 EEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
670 680 690 700 710 720
pF1KB3 HSS
:::
NP_001 HSS
>>NP_001005374 (OMIM: 610933,614436) E3 ubiquitin-protei (723 aa)
initn: 4682 init1: 4682 opt: 4682 Z-score: 1969.3 bits: 375.0 E(85289): 5.9e-103
Smith-Waterman score: 4682; 99.7% identity (100.0% similar) in 723 aa overlap (1-723:1-723)
10 20 30 40 50 60
pF1KB3 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 EEQSRLEQGLSEHQRHLDAERRRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
:::::::::::::::::.:::.::::::::::::::::::::::::::::::::::::::
NP_001 EEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
670 680 690 700 710 720
pF1KB3 HSS
:::
NP_001 HSS
>>NP_612370 (OMIM: 610933,614436) E3 ubiquitin-protein l (723 aa)
initn: 4682 init1: 4682 opt: 4682 Z-score: 1969.3 bits: 375.0 E(85289): 5.9e-103
Smith-Waterman score: 4682; 99.7% identity (100.0% similar) in 723 aa overlap (1-723:1-723)
10 20 30 40 50 60
pF1KB3 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 EEQSRLEQGLSEHQRHLDAERRRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
:::::::::::::::::.:::.::::::::::::::::::::::::::::::::::::::
NP_612 EEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
670 680 690 700 710 720
pF1KB3 HSS
:::
NP_612 HSS
>>XP_006717379 (OMIM: 610933,614436) PREDICTED: E3 ubiqu (690 aa)
initn: 3391 init1: 3391 opt: 3395 Z-score: 1436.0 bits: 276.2 E(85289): 3e-73
Smith-Waterman score: 4395; 95.2% identity (95.4% similar) in 723 aa overlap (1-723:1-690)
10 20 30 40 50 60
pF1KB3 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 EEQSRLEQGLSEHQRHLDAERRRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
:::::::::::::::::.:::.::::::::::::::::::::::::::::::::::::::
XP_006 EEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREIL-------
490 500 510 520 530
550 560 570 580 590 600
pF1KB3 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
::::::::::::::::::::::::::::::::::
XP_006 --------------------------EEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
540 550 560
610 620 630 640 650 660
pF1KB3 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB3 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
630 640 650 660 670 680
pF1KB3 HSS
:::
XP_006 HSS
690
>>NP_001177652 (OMIM: 610933,614436) E3 ubiquitin-protei (696 aa)
initn: 3036 init1: 3036 opt: 3074 Z-score: 1302.8 bits: 251.6 E(85289): 7.9e-66
Smith-Waterman score: 4465; 96.0% identity (96.3% similar) in 723 aa overlap (1-723:1-696)
10 20 30 40 50 60
pF1KB3 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPLFFRKRKPSEEARKRLEYQMCLAKEAGADDILDISKCELSEIPFGAFATCKVLQKKVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DASAMVYPPREVCGAGTAAILQFLCKESGLEYYPPSQYLLPILEQDGIENSRDSPDGPTD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEILQTVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 EEQSRLEQGLSEHQRHLDAERRRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
:::::::::::::::::.:::.::::::::::::::::::::::::::::::::::::::
NP_001 EEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSSEILKSLE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNLVQQACSS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQIKLIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRSQ------
430 440 450 460 470
490 500 510 520 530 540
pF1KB3 ELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
:::::::::::::::::::::::::::::::::::::::
NP_001 ---------------------EMISEQRWALSSLLQQLLKEKQQREEELREILTELEAKS
480 490 500 510
550 560 570 580 590 600
pF1KB3 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHHRLSLDLL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB3 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQEPPESVR
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB3 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIY
640 650 660 670 680 690
pF1KB3 HSS
:::
NP_001 HSS
>>XP_016870773 (OMIM: 610933,614436) PREDICTED: E3 ubiqu (460 aa)
initn: 2961 init1: 2961 opt: 2961 Z-score: 1258.1 bits: 242.7 E(85289): 2.5e-63
Smith-Waterman score: 2961; 99.6% identity (100.0% similar) in 460 aa overlap (264-723:1-460)
240 250 260 270 280 290
pF1KB3 SPDGPTDRFSREELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKD
::::::::::::::::::::::::::::::
XP_016 MLEKLEFERRLELGQREHTQLLQQSSSQKD
10 20 30
300 310 320 330 340 350
pF1KB3 EILQTVKEEQSRLEQGLSEHQRHLDAERRRLQEQLKQTEQNISSRIQKLLQDNQRQKKSS
::::::::::::::::::::::::.:::.:::::::::::::::::::::::::::::::
XP_016 EILQTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQDNQRQKKSS
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB3 EILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCKNRLIQMAYESQRQNL
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB3 VQQACSSMAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQQACSSMAEMDERFQQILSWQQMDQNKAISQILQESAMQKAAFEALQVKKDLMHRQIRS
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB3 QIKLIETELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIKLIETELLQLTQLELKRKSLDTESLQEMISEQRWALSSLLQQLLKEKQQREEELREIL
220 230 240 250 260 270
540 550 560 570 580 590
pF1KB3 TELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELEAKSETRQENYWLIQYQRLLNQKPLSLKLQEEGMERQLVALLEELSAEHYLPIFAHH
280 290 300 310 320 330
600 610 620 630 640 650
pF1KB3 RLSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLSLDLLSQMSPGDLAKVGVSEAGLQHEILRRVQELLDAARIQPELKPPMGEVVTPTAPQ
340 350 360 370 380 390
660 670 680 690 700 710
pF1KB3 EPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDI
400 410 420 430 440 450
720
pF1KB3 AQRLRIYHSS
::::::::::
XP_016 AQRLRIYHSS
460
723 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:54:44 2016 done: Thu Nov 3 20:54:45 2016
Total Scan time: 12.000 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]