Result of FASTA (ccds) for
pFN21AB7024
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7024, 426 aa
1>>>pF1KB7024 426 - 426 aa - 426 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4951+/-0.000732; mu= 14.8056+/- 0.044
mean_var=160.4772+/-32.172, 0's: 0 Z-trim(115.5): 24 B-trim: 0 in 0/50
Lambda= 0.101244
statistics sampled from 16048 (16069) to 16048 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.494), width: 16
Scan time: 3.640
The best scores are: opt bits E(32554)
CCDS11936.1 SMAD7 gene_id:4092|Hs108|chr18 ( 426) 3033 454.4 9.5e-128
CCDS59317.1 SMAD7 gene_id:4092|Hs108|chr18 ( 425) 3016 451.9 5.3e-127
CCDS54186.1 SMAD7 gene_id:4092|Hs108|chr18 ( 211) 1494 229.3 2.8e-60
CCDS10221.1 SMAD6 gene_id:4091|Hs108|chr15 ( 496) 1112 173.9 3.1e-43
>>CCDS11936.1 SMAD7 gene_id:4092|Hs108|chr18 (426 aa)
initn: 3033 init1: 3033 opt: 3033 Z-score: 2407.0 bits: 454.4 E(32554): 9.5e-128
Smith-Waterman score: 3033; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KB7 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
370 380 390 400 410 420
pF1KB7 VIFNSR
::::::
CCDS11 VIFNSR
>>CCDS59317.1 SMAD7 gene_id:4092|Hs108|chr18 (425 aa)
initn: 1588 init1: 1588 opt: 3016 Z-score: 2393.6 bits: 451.9 E(32554): 5.3e-127
Smith-Waterman score: 3016; 99.8% identity (99.8% similar) in 426 aa overlap (1-426:1-425)
10 20 30 40 50 60
pF1KB7 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
CCDS59 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPT-DCPDAVPSSAETGGTNY
190 200 210 220 230
250 260 270 280 290 300
pF1KB7 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
360 370 380 390 400 410
pF1KB7 VIFNSR
::::::
CCDS59 VIFNSR
420
>>CCDS54186.1 SMAD7 gene_id:4092|Hs108|chr18 (211 aa)
initn: 1494 init1: 1494 opt: 1494 Z-score: 1195.7 bits: 229.3 E(32554): 2.8e-60
Smith-Waterman score: 1494; 100.0% identity (100.0% similar) in 211 aa overlap (216-426:1-211)
190 200 210 220 230 240
pF1KB7 INPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNYLAPGG
::::::::::::::::::::::::::::::
CCDS54 MDFLKPTADCPDAVPSSAETGGTNYLAPGG
10 20 30
250 260 270 280 290 300
pF1KB7 LSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDN
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB7 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFS
100 110 120 130 140 150
370 380 390 400 410 420
pF1KB7 IKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 IKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNS
160 170 180 190 200 210
pF1KB7 R
:
CCDS54 R
>>CCDS10221.1 SMAD6 gene_id:4091|Hs108|chr15 (496 aa)
initn: 1307 init1: 559 opt: 1112 Z-score: 889.8 bits: 173.9 E(32554): 3.1e-43
Smith-Waterman score: 1251; 47.7% identity (68.5% similar) in 444 aa overlap (17-425:66-494)
10 20 30
pF1KB7 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGG----GGGELR----
: : ..:: :.: .:: :
CCDS10 DGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSE
40 50 60 70 80 90
40 50 60 70 80
pF1KB7 -GEGATDSRAHGAGGGGPG--------RAGCCLGKAVRGAKGHHHPHPPAAGAG--AAGG
: :: .: : :::: . ::: . .: . . : :::. :::
CCDS10 PGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGG
100 110 120 130 140 150
90 100 110 120 130
pF1KB7 A------------EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGRLDCR
. : .::..:.:.::.::::.:. ::.:::::::. .:.:.: : : :
CCDS10 GRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVP-RADLR
160 170 180 190 200 210
140 150 160 170 180 190
pF1KB7 LGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKI-NPELVCCN
:: .::: ::. ::: ..::::::.:. :.: :: :.:.. . ::::
CCDS10 LG------GQPA-PPQ-----LLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCN
220 230 240 250 260
200 210 220 230 240 250
pF1KB7 PHHLSRLCELESPPPPYSRY-PMDFLKPTADCPDAVPSSAETGGTNYL--APGGLSDSQL
:.:.:::: ::::::::: : : :: : :.. : .:: .:: : ::: .::...
CCDS10 PYHFSRLCGPESPPPPYSRLSPRDEYKPL-DLSDSTLSYTETEATNSLITAPGEFSDASM
270 280 290 300 310 320
260 270 280 290 300 310
pF1KB7 LLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQ
. :::: :::::..::::::: : . ...::::::::.:::::::: ...:. :.
CCDS10 SPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVR
330 340 350 360 370 380
320 330 340 350 360 370
pF1KB7 KVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDY
..::::: :: :..: ::::.:::. .:::..: ::: : .:.:.:.:: ::.:::.::.
CCDS10 RTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDF
390 400 410 420 430 440
380 390 400 410 420
pF1KB7 EKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNSR
:.. .::. . . . :. .:.:::.:::: ::.::::.:::::::...:.
CCDS10 ERS-GLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR
450 460 470 480 490
426 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:16:29 2016 done: Thu Nov 3 18:16:30 2016
Total Scan time: 3.640 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]