Result of FASTA (omim) for
pFN21AB6005
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6005, 1083 aa
1>>>pF1KB6005 1083 - 1083 aa - 1083 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.8362+/-0.000517; mu= -34.4967+/- 0.032
mean_var=594.4535+/-125.596, 0's: 0 Z-trim(121.1): 79 B-trim: 0 in 0/54
Lambda= 0.052604
statistics sampled from 37201 (37311) to 37201 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.437), width: 16
Scan time: 18.450
The best scores are: opt bits E(85289)
NP_001139400 (OMIM: 609697) histone deacetylase co (1083) 7070 552.4 5.1e-156
XP_006712811 (OMIM: 609697) PREDICTED: histone dea (1082) 7053 551.1 1.2e-155
XP_005263824 (OMIM: 609697) PREDICTED: histone dea (1082) 7053 551.1 1.2e-155
XP_005263826 (OMIM: 609697) PREDICTED: histone dea (1057) 6884 538.3 8.8e-152
NP_001317230 (OMIM: 609697) histone deacetylase co (1057) 6884 538.3 8.8e-152
NP_001317231 (OMIM: 609697) histone deacetylase co (1056) 6867 537.0 2.1e-151
NP_001317228 (OMIM: 609697) histone deacetylase co (1056) 6867 537.0 2.1e-151
NP_078821 (OMIM: 609697) histone deacetylase compl (1048) 4497 357.2 3e-97
XP_006712812 (OMIM: 609697) PREDICTED: histone dea (1047) 4480 355.9 7.2e-97
NP_001317232 (OMIM: 609697) histone deacetylase co (1022) 4311 343.0 5.1e-93
NP_001317229 (OMIM: 609697) histone deacetylase co (1021) 4294 341.7 1.3e-92
NP_001035194 (OMIM: 608424) mucin-17 precursor [Ho (4493) 440 49.5 0.00052
NP_001291288 (OMIM: 158373) mucin-5AC precursor [H (5654) 417 47.8 0.0021
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 398 46.2 0.0024
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 398 46.2 0.0024
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 398 46.2 0.0024
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 398 46.2 0.0024
>>NP_001139400 (OMIM: 609697) histone deacetylase comple (1083 aa)
initn: 7070 init1: 7070 opt: 7070 Z-score: 2922.1 bits: 552.4 E(85289): 5.1e-156
Smith-Waterman score: 7070; 100.0% identity (100.0% similar) in 1083 aa overlap (1-1083:1-1083)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
1030 1040 1050 1060 1070 1080
pF1KB6 EKV
:::
NP_001 EKV
>>XP_006712811 (OMIM: 609697) PREDICTED: histone deacety (1082 aa)
initn: 4065 init1: 4065 opt: 7053 Z-score: 2915.1 bits: 551.1 E(85289): 1.2e-155
Smith-Waterman score: 7053; 99.9% identity (99.9% similar) in 1083 aa overlap (1-1083:1-1082)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_006 GLQPAPMGTQQPQPEGKTS-VVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
610 620 630 640 650
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
1020 1030 1040 1050 1060 1070
pF1KB6 EKV
:::
XP_006 EKV
1080
>>XP_005263824 (OMIM: 609697) PREDICTED: histone deacety (1082 aa)
initn: 5022 init1: 5022 opt: 7053 Z-score: 2915.1 bits: 551.1 E(85289): 1.2e-155
Smith-Waterman score: 7053; 99.9% identity (99.9% similar) in 1083 aa overlap (1-1083:1-1082)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVITTTAAHATDSAL-RPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
310 320 330 340 350
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
1020 1030 1040 1050 1060 1070
pF1KB6 EKV
:::
XP_005 EKV
1080
>>XP_005263826 (OMIM: 609697) PREDICTED: histone deacety (1057 aa)
initn: 6884 init1: 6884 opt: 6884 Z-score: 2846.0 bits: 538.3 E(85289): 8.8e-152
Smith-Waterman score: 6884; 100.0% identity (100.0% similar) in 1057 aa overlap (27-1083:1-1057)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::
XP_005 MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
1000 1010 1020 1030 1040 1050
pF1KB6 EKV
:::
XP_005 EKV
>>NP_001317230 (OMIM: 609697) histone deacetylase comple (1057 aa)
initn: 6884 init1: 6884 opt: 6884 Z-score: 2846.0 bits: 538.3 E(85289): 8.8e-152
Smith-Waterman score: 6884; 100.0% identity (100.0% similar) in 1057 aa overlap (27-1083:1-1057)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::
NP_001 MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
1000 1010 1020 1030 1040 1050
pF1KB6 EKV
:::
NP_001 EKV
>>NP_001317231 (OMIM: 609697) histone deacetylase comple (1056 aa)
initn: 3879 init1: 3879 opt: 6867 Z-score: 2839.0 bits: 537.0 E(85289): 2.1e-151
Smith-Waterman score: 6867; 99.9% identity (99.9% similar) in 1057 aa overlap (27-1083:1-1056)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::
NP_001 MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTS-VVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
1000 1010 1020 1030 1040 1050
pF1KB6 EKV
:::
NP_001 EKV
>>NP_001317228 (OMIM: 609697) histone deacetylase comple (1056 aa)
initn: 5022 init1: 5022 opt: 6867 Z-score: 2839.0 bits: 537.0 E(85289): 2.1e-151
Smith-Waterman score: 6867; 99.9% identity (99.9% similar) in 1057 aa overlap (27-1083:1-1056)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::
NP_001 MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSAL-RPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
1000 1010 1020 1030 1040 1050
pF1KB6 EKV
:::
NP_001 EKV
>>NP_078821 (OMIM: 609697) histone deacetylase complex s (1048 aa)
initn: 4416 init1: 4416 opt: 4497 Z-score: 1867.0 bits: 357.2 E(85289): 3e-97
Smith-Waterman score: 6755; 96.8% identity (96.8% similar) in 1083 aa overlap (1-1083:1-1048)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::: ::::::
NP_078 AQGSSPRPSILRKKPATDG-----------------------------------AKPKSE
670 680
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
750 760 770 780 790 800
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
810 820 830 840 850 860
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
990 1000 1010 1020 1030 1040
pF1KB6 EKV
:::
NP_078 EKV
>>XP_006712812 (OMIM: 609697) PREDICTED: histone deacety (1047 aa)
initn: 6459 init1: 4046 opt: 4480 Z-score: 1860.0 bits: 355.9 E(85289): 7.2e-97
Smith-Waterman score: 6738; 96.7% identity (96.7% similar) in 1083 aa overlap (1-1083:1-1047)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_006 GLQPAPMGTQQPQPEGKTS-VVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
610 620 630 640 650
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::: ::::::
XP_006 AQGSSPRPSILRKKPATDG-----------------------------------AKPKSE
660 670 680
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
750 760 770 780 790 800
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
810 820 830 840 850 860
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
990 1000 1010 1020 1030 1040
pF1KB6 EKV
:::
XP_006 EKV
>>NP_001317232 (OMIM: 609697) histone deacetylase comple (1022 aa)
initn: 4230 init1: 4230 opt: 4311 Z-score: 1790.9 bits: 343.0 E(85289): 5.1e-93
Smith-Waterman score: 6569; 96.7% identity (96.7% similar) in 1057 aa overlap (27-1083:1-1022)
10 20 30 40 50 60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
::::::::::::::::::::::::::::::::::
NP_001 MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
10 20 30
70 80 90 100 110 120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
::::::::::::::::::: ::::::
NP_001 AQGSSPRPSILRKKPATDG-----------------------------------AKPKSE
640 650
730 740 750 760 770 780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
660 670 680 690 700 710
790 800 810 820 830 840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
720 730 740 750 760 770
850 860 870 880 890 900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
780 790 800 810 820 830
910 920 930 940 950 960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
960 970 980 990 1000 1010
pF1KB6 EKV
:::
NP_001 EKV
1020
1083 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:04:26 2016 done: Thu Nov 3 18:04:29 2016
Total Scan time: 18.450 Total Display time: 0.560
Function used was FASTA [36.3.4 Apr, 2011]