Result of FASTA (omim) for
pFN21AB5697
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5697, 660 aa
1>>>pF1KB5697 660 - 660 aa - 660 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4136+/-0.00037; mu= 19.0222+/- 0.023
mean_var=81.4523+/-16.144, 0's: 0 Z-trim(113.3): 131 B-trim: 0 in 0/56
Lambda= 0.142109
statistics sampled from 22442 (22574) to 22442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.265), width: 16
Scan time: 10.130
The best scores are: opt bits E(85289)
NP_004521 (OMIM: 120360,259600) 72 kDa type IV col ( 660) 4703 974.6 0
NP_001121363 (OMIM: 120360,259600) 72 kDa type IV ( 610) 4369 906.1 0
NP_001289437 (OMIM: 120360,259600) 72 kDa type IV ( 584) 4193 870.0 0
NP_001289439 (OMIM: 120360,259600) 72 kDa type IV ( 584) 4193 870.0 0
NP_001289438 (OMIM: 120360,259600) 72 kDa type IV ( 584) 4193 870.0 0
NP_004985 (OMIM: 120361,613073) matrix metalloprot ( 707) 1901 400.1 1.4e-110
NP_002418 (OMIM: 250400,600108,602111) collagenase ( 471) 705 154.8 6.6e-37
NP_002414 (OMIM: 178990) matrilysin preproprotein ( 267) 657 144.8 3.9e-34
NP_002413 (OMIM: 185250,614466) stromelysin-1 prep ( 477) 658 145.2 5.3e-34
NP_002416 (OMIM: 185260) stromelysin-2 preproprote ( 476) 638 141.1 9.1e-33
NP_004762 (OMIM: 604629,612529) matrix metalloprot ( 483) 637 140.9 1.1e-32
NP_002417 (OMIM: 601046) macrophage metalloelastas ( 470) 628 139.0 3.8e-32
NP_002412 (OMIM: 120353,226600,606963) interstitia ( 469) 594 132.0 4.7e-30
NP_002415 (OMIM: 120355) neutrophil collagenase is ( 467) 574 127.9 8e-29
XP_011541138 (OMIM: 120355) PREDICTED: neutrophil ( 377) 569 126.8 1.4e-28
NP_001139410 (OMIM: 120353,226600,606963) intersti ( 403) 569 126.9 1.5e-28
XP_011541136 (OMIM: 120355) PREDICTED: neutrophil ( 476) 569 126.9 1.7e-28
NP_001291370 (OMIM: 120355) neutrophil collagenase ( 444) 565 126.1 2.8e-28
NP_001291371 (OMIM: 120355) neutrophil collagenase ( 444) 565 126.1 2.8e-28
XP_016873260 (OMIM: 120355) PREDICTED: neutrophil ( 444) 565 126.1 2.8e-28
XP_011541137 (OMIM: 120355) PREDICTED: neutrophil ( 444) 565 126.1 2.8e-28
NP_005932 (OMIM: 602262) matrix metalloproteinase- ( 607) 533 119.6 3.3e-26
NP_002419 (OMIM: 602261) matrix metalloproteinase- ( 669) 514 115.8 5.3e-25
NP_473375 (OMIM: 135600,601894,614101) fibronectin ( 657) 509 114.7 1.1e-24
NP_997639 (OMIM: 135600,601894,614101) fibronectin (2176) 509 115.1 2.7e-24
NP_001293061 (OMIM: 135600,601894,614101) fibronec (2240) 509 115.1 2.8e-24
XP_005246473 (OMIM: 135600,601894,614101) PREDICTE (2246) 509 115.1 2.8e-24
NP_001293060 (OMIM: 135600,601894,614101) fibronec (2265) 509 115.1 2.8e-24
XP_005246471 (OMIM: 135600,601894,614101) PREDICTE (2266) 509 115.1 2.8e-24
NP_001293059 (OMIM: 135600,601894,614101) fibronec (2267) 509 115.1 2.8e-24
XP_005246469 (OMIM: 135600,601894,614101) PREDICTE (2271) 509 115.1 2.8e-24
XP_005246468 (OMIM: 135600,601894,614101) PREDICTE (2273) 509 115.1 2.8e-24
NP_997641 (OMIM: 135600,601894,614101) fibronectin (2296) 509 115.1 2.8e-24
XP_016859184 (OMIM: 135600,601894,614101) PREDICTE (2302) 509 115.1 2.8e-24
NP_997643 (OMIM: 135600,601894,614101) fibronectin (2330) 509 115.2 2.8e-24
XP_016859183 (OMIM: 135600,601894,614101) PREDICTE (2331) 509 115.2 2.8e-24
XP_005246467 (OMIM: 135600,601894,614101) PREDICTE (2337) 509 115.2 2.8e-24
NP_002017 (OMIM: 135600,601894,614101) fibronectin (2355) 509 115.2 2.9e-24
XP_016859182 (OMIM: 135600,601894,614101) PREDICTE (2356) 509 115.2 2.9e-24
XP_016859181 (OMIM: 135600,601894,614101) PREDICTE (2357) 509 115.2 2.9e-24
XP_005246466 (OMIM: 135600,601894,614101) PREDICTE (2361) 509 115.2 2.9e-24
XP_005246465 (OMIM: 135600,601894,614101) PREDICTE (2362) 509 115.2 2.9e-24
XP_005246464 (OMIM: 135600,601894,614101) PREDICTE (2363) 509 115.2 2.9e-24
XP_005246463 (OMIM: 135600,601894,614101) PREDICTE (2386) 509 115.2 2.9e-24
XP_005246462 (OMIM: 135600,601894,614101) PREDICTE (2387) 509 115.2 2.9e-24
XP_005246461 (OMIM: 135600,601894,614101) PREDICTE (2392) 509 115.2 2.9e-24
XP_005246460 (OMIM: 135600,601894,614101) PREDICTE (2393) 509 115.2 2.9e-24
XP_005246459 (OMIM: 135600,601894,614101) PREDICTE (2421) 509 115.2 2.9e-24
XP_005246458 (OMIM: 135600,601894,614101) PREDICTE (2427) 509 115.2 2.9e-24
NP_001293058 (OMIM: 135600,601894,614101) fibronec (2446) 509 115.2 2.9e-24
>>NP_004521 (OMIM: 120360,259600) 72 kDa type IV collage (660 aa)
initn: 4703 init1: 4703 opt: 4703 Z-score: 5211.4 bits: 974.6 E(85289): 0
Smith-Waterman score: 4703; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660)
10 20 30 40 50 60
pF1KB5 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
610 620 630 640 650 660
>>NP_001121363 (OMIM: 120360,259600) 72 kDa type IV coll (610 aa)
initn: 4369 init1: 4369 opt: 4369 Z-score: 4841.8 bits: 906.1 E(85289): 0
Smith-Waterman score: 4369; 99.8% identity (100.0% similar) in 610 aa overlap (51-660:1-610)
30 40 50 60 70 80
pF1KB5 GCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKF
.:::::::::::::::::::::::::::::
NP_001 MQYLNTFYGCPKESCNLFVLKDTLKKMQKF
10 20 30
90 100 110 120 130 140
pF1KB5 FGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETV
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB5 DDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTG
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB5 VGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB5 TTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTT
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB5 EDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTAN
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB5 YDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKG
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB5 IQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPR
400 410 420 430 440 450
510 520 530 540 550 560
pF1KB5 DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLG
460 470 480 490 500 510
570 580 590 600 610 620
pF1KB5 LPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAV
520 530 540 550 560 570
630 640 650 660
pF1KB5 VDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
::::::::::::::::::::::::::::::::::::::::
NP_001 VDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
580 590 600 610
>>NP_001289437 (OMIM: 120360,259600) 72 kDa type IV coll (584 aa)
initn: 4193 init1: 4193 opt: 4193 Z-score: 4647.0 bits: 870.0 E(85289): 0
Smith-Waterman score: 4193; 100.0% identity (100.0% similar) in 584 aa overlap (77-660:1-584)
50 60 70 80 90 100
pF1KB5 KELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPD
::::::::::::::::::::::::::::::
NP_001 MQKFFGLPQTGDLDQNTIETMRKPRCGNPD
10 20 30
110 120 130 140 150 160
pF1KB5 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB5 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB5 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB5 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
460 470 480 490 500 510
590 600 610 620 630 640
pF1KB5 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
520 530 540 550 560 570
650 660
pF1KB5 SVKFGSIKSDWLGC
::::::::::::::
NP_001 SVKFGSIKSDWLGC
580
>>NP_001289439 (OMIM: 120360,259600) 72 kDa type IV coll (584 aa)
initn: 4193 init1: 4193 opt: 4193 Z-score: 4647.0 bits: 870.0 E(85289): 0
Smith-Waterman score: 4193; 100.0% identity (100.0% similar) in 584 aa overlap (77-660:1-584)
50 60 70 80 90 100
pF1KB5 KELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPD
::::::::::::::::::::::::::::::
NP_001 MQKFFGLPQTGDLDQNTIETMRKPRCGNPD
10 20 30
110 120 130 140 150 160
pF1KB5 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB5 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB5 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB5 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
460 470 480 490 500 510
590 600 610 620 630 640
pF1KB5 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
520 530 540 550 560 570
650 660
pF1KB5 SVKFGSIKSDWLGC
::::::::::::::
NP_001 SVKFGSIKSDWLGC
580
>>NP_001289438 (OMIM: 120360,259600) 72 kDa type IV coll (584 aa)
initn: 4193 init1: 4193 opt: 4193 Z-score: 4647.0 bits: 870.0 E(85289): 0
Smith-Waterman score: 4193; 100.0% identity (100.0% similar) in 584 aa overlap (77-660:1-584)
50 60 70 80 90 100
pF1KB5 KELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPD
::::::::::::::::::::::::::::::
NP_001 MQKFFGLPQTGDLDQNTIETMRKPRCGNPD
10 20 30
110 120 130 140 150 160
pF1KB5 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB5 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB5 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB5 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
460 470 480 490 500 510
590 600 610 620 630 640
pF1KB5 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
520 530 540 550 560 570
650 660
pF1KB5 SVKFGSIKSDWLGC
::::::::::::::
NP_001 SVKFGSIKSDWLGC
580
>>NP_004985 (OMIM: 120361,613073) matrix metalloproteina (707 aa)
initn: 2044 init1: 1228 opt: 1901 Z-score: 2106.3 bits: 400.1 E(85289): 1.4e-110
Smith-Waterman score: 2106; 46.7% identity (68.7% similar) in 696 aa overlap (9-644:2-686)
10 20 30 40 50
pF1KB5 MEALMARGALTGPLR-ALCLLGCLLSHAAAAPSPIIKFPGDVAPK-TDKELAVQYLNTFY
.: :: .: .::: .. : .. ::::. . ::..:: .:: :
NP_004 MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYR-Y
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 GCPK------ESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF
: . :: .: .: .:: ..::.::.::. :...:: :::: ::.. ..
NP_004 GYTRVAEMRGESKSL---GPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQT
60 70 80 90 100
120 130 140 150 160 170
pF1KB5 FPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMIN
: :: ...::: : .:. :: ..:::::::: .:: :::: :.:... .:::.:.
NP_004 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQ
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEY
:: ::::::::::::::::::: :: :. ::.::::::::.::.: :: ...:::::
NP_004 FGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 CKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCK
:.:::.:.:. :..:: :::::. ::::: :.. : ..:::: : :.:. :::.:.::.
NP_004 CHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQ
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 FPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTV-GGNSEGAPCVF
::: ::: ::..:::.::.::::::.:: .::::: .:::: : ::: :::: : :::
NP_004 FPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVF
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 PFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGL
::::::..: .::: ::.::..:::::.:.:.:.:::::::::::::::::::::::.::
NP_004 PFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGL
350 360 370 380 390 400
420 430 440 450
pF1KB5 EHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDID-----------------LG
.::. : ::: :.: .:.. : .::..::..::: :. .
NP_004 DHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCP
410 420 430 440 450 460
460 470 480
pF1KB5 TGPT-------PTLGPVTP-------------------------EICKQDIVFDGIAQIR
::: :: ::. : . :. .: ::.::.:
NP_004 TGPPTVHPSERPTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNI-FDAIAEIG
470 480 490 500 510 520
490 500 510 520 530 540
pF1KB5 GEIFFFKDRFIWRTVTPR-DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYW
.....::: :: : ..:.::.:.: :: ::.:.:.:.: .: ::.: . :
NP_004 NQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVW
530 540 550 560 570 580
550 560 570 580 590 600
pF1KB5 IYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM-DP
.:..... : :. : .::: :: .: .:. : : .:.: ..::.. :: .: ::
NP_004 VYTGASVL-G-PRRLDKLGLGADVAQVTGALR-SGRGKMLLFSGRRLWRFD-VKAQMVDP
590 600 610 620 630 640
610 620 630 640 650 660
pF1KB5 GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
. . . ..: ::. .: ..:: . .: .. ..:
NP_004 RSASEVDRMFPGVP--LDTHDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDIL
650 660 670 680 690 700
NP_004 QCPED
>>NP_002418 (OMIM: 250400,600108,602111) collagenase 3 p (471 aa)
initn: 1259 init1: 681 opt: 705 Z-score: 783.5 bits: 154.8 E(85289): 6.6e-37
Smith-Waterman score: 1083; 34.2% identity (52.6% similar) in 646 aa overlap (12-649:4-461)
10 20 30 40 50
pF1KB5 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFY--
: : :. .:. .: : : : :.. . : ..: .:: ..:
NP_002 MHPGVLAAFLFLS--WTHCRALPLPSGGDEDDLS-EEDLQFAERYLRSYYHP
10 20 30 40
60 70 80 90 100 110
pF1KB5 ----GCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFP
: ::. . . :..::.:::: :: ::.::...:.::::: :::..:: ::
NP_002 TNLAGILKENAAS-SMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 RKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFG
: ::.: ..::::..::::. :. :: .::.:::::::: :.:.::: :::::.::
NP_002 RTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 RWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCK
:::: ::::: .::::::: :: . :::.:::::: ::
NP_002 IKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWT--------------------
170 180 190 200
240 250 260 270 280 290
pF1KB5 FPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFP
:..
NP_002 -------------------------SSS--------------------------------
210
300 310 320 330 340 350
pF1KB5 FRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFT
NP_002 ------------------------------------------------------------
360 370 380 390 400 410
pF1KB5 FLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHS
.::.:::::::::::..::.::
NP_002 --------------------------------------KGYNLFLVAAHEFGHSLGLDHS
220 230
420 430 440 450 460 470
pF1KB5 QDPGALMAPIYTYT--KNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQD
.:::::: :::::: ..: : .::..::: ::: . : : :.: : ::. : .
NP_002 KDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG-DED----PNPK-HPKTPDKCDPS
240 250 260 270 280
480 490 500 510 520 530
pF1KB5 IVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKA
. .:.:...::: ..:::::.:: . :.. .:. .::::::..:::.:: :...
NP_002 LSLDAITSLRGETMIFKDRFFWR-LHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLI
290 300 310 320 330 340
540 550 560 570 580 590
pF1KB5 VFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYN
.: : ..: .. . .:::: .. :::: .:....:: .. . :: .:.:.. :::.
NP_002 FIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYD
350 360 370 380 390 400
600 610 620 630 640 650
pF1KB5 EVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGS
.... :: .:.:: . . .: :..::: . .:. :::.: .. : . :.
NP_002 DTNHIMDKDYPRLIEEDFPGIGDKVDAVYE--KNGYIYFFNGPIQFEYSIWSNRIVRVMP
410 420 430 440 450 460
660
pF1KB5 IKSDWLGC
NP_002 ANSILWC
470
>>NP_002414 (OMIM: 178990) matrilysin preproprotein [Hom (267 aa)
initn: 811 init1: 625 opt: 657 Z-score: 733.7 bits: 144.8 E(85289): 3.9e-34
Smith-Waterman score: 657; 50.7% identity (71.9% similar) in 203 aa overlap (14-216:3-201)
10 20 30 40 50 60
pF1KB5 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
: .:: . ::: . : : : . : .. . . : : .::. ::
NP_002 MRLTVLCAV-CLLPGSLALPLP--QEAGGMS-ELQWEQAQDYLKRFYLY
10 20 30 40
70 80 90 100 110 120
pF1KB5 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
.:. : :. ::.:::::::: :: :.. .:: :.::::: ::::.:..:: .:::
NP_002 DSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
.. .::::..:: :: ::: ..:...:. ::.: .. : :::::.:.: :::
NP_002 SKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
.::::: . ::::::::::.:::.:::.:: :: :
NP_002 SYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHS
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
NP_002 SDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
230 240 250 260
>--
initn: 200 init1: 108 opt: 209 Z-score: 237.3 bits: 52.9 E(85289): 1.8e-06
Smith-Waterman score: 209; 54.5% identity (81.8% similar) in 55 aa overlap (394-446:205-259)
370 380 390 400 410 420
pF1KB5 TSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAP
: ... .:.::.::..:. ::.::.:.: :
NP_002 TLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYP
180 190 200 210 220 230
430 440 450 460 470 480
pF1KB5 IYTY--TKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQI
: .::.::::::::::.:::
NP_002 TYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
240 250 260
>>NP_002413 (OMIM: 185250,614466) stromelysin-1 prepropr (477 aa)
initn: 1283 init1: 639 opt: 658 Z-score: 731.4 bits: 145.2 E(85289): 5.3e-34
Smith-Waterman score: 1046; 33.5% identity (53.0% similar) in 641 aa overlap (37-660:18-477)
10 20 30 40 50 60
pF1KB5 RGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPK---TDKELAVQYLNTFYGCPKE
.: : : . :. .:. .::...: :.
NP_002 MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKD
10 20 30 40
70 80 90 100 110
pF1KB5 SCNLFVLKDT------LKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKP
.. ::. ...::::.:: :: ::..:.:.::::::: :::... :: :
NP_002 VKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 KWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWE
:: :...::::..::::: ..::.: .:..:: .:::: :::...:::::::.:. :
NP_002 KWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVRE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 HGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPF
::: ::::: ..::::.::: :..::.:::::: ::
NP_002 HGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWT-----------------------
170 180 190 200
240 250 260 270 280 290
pF1KB5 LFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRF
::
NP_002 -----------------------------KD-----------------------------
300 310 320 330 340 350
pF1KB5 QGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLG
:.: :
NP_002 -----------------------------------------TTGTN--------------
210
360 370 380 390 400 410
pF1KB5 NKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDP
::::::::.::..:: :: .
NP_002 ---------------------------------------LFLVAAHEIGHSLGLFHSANT
220 230
420 430 440 450 460 470
pF1KB5 GALMAPIY---TYTKNFRLSQDDIKGIQELYGASPDID----LGTGPTPTLGPVTPEICK
::: :.: : ::::::::.::: ::: :: . : :.: : :: :
NP_002 EALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPE-PGTPANCD
240 250 260 270 280 290
480 490 500 510 520 530
pF1KB5 QDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEE
. ::... .::::..:::: .:: . .: : ...::: :: .::.::. ...
NP_002 PALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHL-ISSFWPSLPSGVDAAYEVTSKD
300 310 320 330 340 350
540 550 560 570 580 590
pF1KB5 KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR
. .: ::..: .. .. :::. . .::.:: :...:::.. ....:::.:. ::.::
NP_002 LVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWR
360 370 380 390 400 410
600 610 620 630 640 650
pF1KB5 YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF
..: ...:.::::: ::. . .: ...::: .. : ::: :. :... .. : ..
NP_002 FDEKRNSMEPGFPKQIAEDFPGIDSKIDAV--FEEFGFFYFFTGSSQLEFDPNAKKVTH-
420 430 440 450 460
660
pF1KB5 GSIKSD-WLGC
..::. ::.:
NP_002 -TLKSNSWLNC
470
>>NP_002416 (OMIM: 185260) stromelysin-2 preproprotein [ (476 aa)
initn: 1339 init1: 601 opt: 638 Z-score: 709.2 bits: 141.1 E(85289): 9.1e-33
Smith-Waterman score: 1016; 33.6% identity (52.2% similar) in 628 aa overlap (45-660:29-476)
20 30 40 50 60 70
pF1KB5 RALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDT-
..:.:: :::. .:. :. . : ::.
NP_002 MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKD-VKQFRRKDSN
10 20 30 40 50
80 90 100 110 120
pF1KB5 --LKK---MQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRI
.:: ::::.:: :: :: .:.:.::::::: :::.... :: ::: :...::::
NP_002 LIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKD
..::::: ..::.:. .:..:: .:::: :::...:::::::.:. :::: : :::
NP_002 VNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 GLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCT
::::. :: :. :: :::::: ::
NP_002 HSLAHAYPPGPGLYGDIHFDDDEKWT----------------------------------
180 190 200
250 260 270 280 290 300
pF1KB5 DTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTE
NP_002 ------------------------------------------------------------
310 320 330 340 350 360
pF1KB5 GRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGR
:: .
NP_002 ------------EDAS--------------------------------------------
370 380 390 400 410 420
pF1KB5 SDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIY-TY
: .::::::::.::..:: :: . ::: :.: ..
NP_002 -------------------------GTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSF
210 220 230 240
430 440 450 460 470 480
pF1KB5 TK--NFRLSQDDIKGIQELYGASP-DIDLGTGPTPTL--GPVTPEICKQDIVFDGIAQIR
:. .:::::::..::: ::: : . . :: .. : : : . ::.:. .:
NP_002 TELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLR
250 260 270 280 290 300
490 500 510 520 530 540
pF1KB5 GEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWI
:: .:::::..:: .: :. : ::: :: .::.::. ... . .: :::.:
NP_002 GEYLFFKDRYFWRRSHWNPEPEFHLISA-FWPSLPSYLDAAYEVNSRDTVFIFKGNEFWA
310 320 330 340 350 360
550 560 570 580 590 600
pF1KB5 YSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGF
.. .. :::. . .::.:: ....::: . ...::::.::.::.::..: ...:. ::
NP_002 IRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGF
370 380 390 400 410 420
610 620 630 640 650 660
pF1KB5 PKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
:.:::: . .. ..::: ::. : :::.:. .... .. . : ...:: :
NP_002 PRLIADDFPGVEPKVDAV--LQAFGFFYFFSGSSQFEFDPNA-RMVTHILKSNSWLHC
430 440 450 460 470
660 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:02:19 2016 done: Thu Nov 3 18:02:20 2016
Total Scan time: 10.130 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]