Result of FASTA (omim) for
pFN21AB5576
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5576, 164 aa
1>>>pF1KB5576 164 - 164 aa - 164 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6677+/-0.000252; mu= 12.0570+/- 0.016
mean_var=82.9474+/-16.406, 0's: 0 Z-trim(122.7): 11 B-trim: 373 in 1/57
Lambda= 0.140823
statistics sampled from 41138 (41149) to 41138 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.482), width: 16
Scan time: 5.460
The best scores are: opt bits E(85289)
NP_000380 (OMIM: 116899) cyclin-dependent kinase i ( 164) 1144 240.7 8e-64
NP_510867 (OMIM: 116899) cyclin-dependent kinase i ( 164) 1144 240.7 8e-64
NP_001207707 (OMIM: 116899) cyclin-dependent kinas ( 164) 1144 240.7 8e-64
NP_001207706 (OMIM: 116899) cyclin-dependent kinas ( 164) 1144 240.7 8e-64
NP_001278478 (OMIM: 116899) cyclin-dependent kinas ( 198) 1144 240.8 9.3e-64
NP_004055 (OMIM: 600778,610755) cyclin-dependent k ( 198) 220 53.0 3e-07
XP_005252789 (OMIM: 130650,600856,614732) PREDICTE ( 175) 175 43.9 0.00015
NP_001116103 (OMIM: 130650,600856,614732) cyclin-d ( 305) 177 44.4 0.00018
NP_001116102 (OMIM: 130650,600856,614732) cyclin-d ( 305) 177 44.4 0.00018
NP_000067 (OMIM: 130650,600856,614732) cyclin-depe ( 316) 177 44.4 0.00019
XP_016872577 (OMIM: 130650,600856,614732) PREDICTE ( 316) 177 44.4 0.00019
>>NP_000380 (OMIM: 116899) cyclin-dependent kinase inhib (164 aa)
initn: 1144 init1: 1144 opt: 1144 Z-score: 1266.8 bits: 240.7 E(85289): 8e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:1-164)
10 20 30 40 50 60
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPLE
:::::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::
NP_000 MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
70 80 90 100 110 120
130 140 150 160
pF1KB5 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
130 140 150 160
>>NP_510867 (OMIM: 116899) cyclin-dependent kinase inhib (164 aa)
initn: 1144 init1: 1144 opt: 1144 Z-score: 1266.8 bits: 240.7 E(85289): 8e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:1-164)
10 20 30 40 50 60
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPLE
:::::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::
NP_510 MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
70 80 90 100 110 120
130 140 150 160
pF1KB5 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
::::::::::::::::::::::::::::::::::::::::::::
NP_510 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
130 140 150 160
>>NP_001207707 (OMIM: 116899) cyclin-dependent kinase in (164 aa)
initn: 1144 init1: 1144 opt: 1144 Z-score: 1266.8 bits: 240.7 E(85289): 8e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:1-164)
10 20 30 40 50 60
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPLE
:::::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::
NP_001 MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
70 80 90 100 110 120
130 140 150 160
pF1KB5 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
130 140 150 160
>>NP_001207706 (OMIM: 116899) cyclin-dependent kinase in (164 aa)
initn: 1144 init1: 1144 opt: 1144 Z-score: 1266.8 bits: 240.7 E(85289): 8e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:1-164)
10 20 30 40 50 60
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPLE
:::::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::
NP_001 MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
70 80 90 100 110 120
130 140 150 160
pF1KB5 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
130 140 150 160
>>NP_001278478 (OMIM: 116899) cyclin-dependent kinase in (198 aa)
initn: 1144 init1: 1144 opt: 1144 Z-score: 1265.6 bits: 240.8 E(85289): 9.3e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:35-198)
10 20 30
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQL
:::::::::::::::::::::::::::.::
NP_001 FRRQTTHSSNPPLPGQQSCCNHRDFFCSGAMSEPAGDVRQNPCGSKACRRLFGPVDSEQL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 RRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 GGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDF
130 140 150 160 170 180
160
pF1KB5 YHSKRRLIFSKRKP
::::::::::::::
NP_001 YHSKRRLIFSKRKP
190
>>NP_004055 (OMIM: 600778,610755) cyclin-dependent kinas (198 aa)
initn: 219 init1: 195 opt: 220 Z-score: 251.1 bits: 53.0 E(85289): 3e-07
Smith-Waterman score: 220; 32.3% identity (57.0% similar) in 158 aa overlap (7-155:17-166)
10 20 30 40
pF1KB5 MSEPAGDVRQ--NPCGSKACRRLFGPVDSDQLRRDCDALMAGC--IQEAR
:.:: .: : ::: :::::: ..: :: : : ..::
NP_004 MSNVRVSNGSPSLERMDARQAEHPKPS-ACRNLFGPVDHEELTRD---LEKHCRDMEEAS
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 ER-WNFDFVTETPLEGDFAWERVRGLGLPKLYL-PTGPRRGRDELGGGRRP---GTSPAL
.: ::::: .. :::: . :..:. .::..: : : .: .. . . :. ::
NP_004 QRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 LQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSK
: . : : . :.. . .... : . : ..: .. . ..::
NP_004 PLIGAPANSEDTHL---VDPKT-DPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEE
120 130 140 150 160 170
pF1KB5 RKP
NP_004 NVSDGSPNAGSVEQTPKKPGLRRRQT
180 190
>>XP_005252789 (OMIM: 130650,600856,614732) PREDICTED: c (175 aa)
initn: 194 init1: 154 opt: 175 Z-score: 202.5 bits: 43.9 E(85289): 0.00015
Smith-Waterman score: 175; 31.3% identity (56.0% similar) in 134 aa overlap (15-141:16-143)
10 20 30 40 50
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPL
..::: :::::: ..: :. .: .: : ..::..:: . ::
XP_005 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 EGD--FAWERVRGLGLPKLYLPT----GPRRGRDELGGGRRPGTSPALLQGTAEEDHVDL
.: . : .: . ..: .: : .: .::. .:: . :: . : :
XP_005 RGPGRLQWTEVDSDSVPAFYRETVQISSPS-ARDQRLRSRR-AMSPRRVPLQAPP----L
70 80 90 100 110
120 130 140 150 160
pF1KB5 SLSCTLVPRSGEQAEGSPGGP-GDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
. . ::. .: .: : :. :..
XP_005 AWARWSRPRARGCGEPKPKEPRGNLPGQRTLEGRWASAGTVHVAATGGGCRRAAFGFVFK
120 130 140 150 160 170
>>NP_001116103 (OMIM: 130650,600856,614732) cyclin-depen (305 aa)
initn: 173 init1: 152 opt: 177 Z-score: 201.2 bits: 44.4 E(85289): 0.00018
Smith-Waterman score: 177; 37.3% identity (63.9% similar) in 83 aa overlap (15-95:16-97)
10 20 30 40 50
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPL
..::: :::::: ..: :. .: .: : ..::..:: . ::
NP_001 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 EGD--FAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSC
.: . : .: . ..: .: : . :: .: . ::
NP_001 RGPGRLQWTEVDSDSVPAFYRET-VQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLE
70 80 90 100 110
120 130 140 150 160
pF1KB5 TLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
NP_001 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP
120 130 140 150 160 170
>>NP_001116102 (OMIM: 130650,600856,614732) cyclin-depen (305 aa)
initn: 173 init1: 152 opt: 177 Z-score: 201.2 bits: 44.4 E(85289): 0.00018
Smith-Waterman score: 177; 37.3% identity (63.9% similar) in 83 aa overlap (15-95:16-97)
10 20 30 40 50
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPL
..::: :::::: ..: :. .: .: : ..::..:: . ::
NP_001 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 EGD--FAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSC
.: . : .: . ..: .: : . :: .: . ::
NP_001 RGPGRLQWTEVDSDSVPAFYRET-VQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLE
70 80 90 100 110
120 130 140 150 160
pF1KB5 TLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
NP_001 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP
120 130 140 150 160 170
>>NP_000067 (OMIM: 130650,600856,614732) cyclin-dependen (316 aa)
initn: 173 init1: 152 opt: 177 Z-score: 201.0 bits: 44.4 E(85289): 0.00019
Smith-Waterman score: 177; 37.3% identity (63.9% similar) in 83 aa overlap (15-95:27-108)
10 20 30 40
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARER
..::: :::::: ..: :. .: .: : ..:
NP_000 MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 WNFDFVTETPLEGD--FAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTA
:..:: . ::.: . : .: . ..: .: : . :: .: . ::
NP_000 WDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRET-VQVGRCRLLLAPRPVAVAVAVSPPL
70 80 90 100 110
110 120 130 140 150 160
pF1KB5 EEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
NP_000 EPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLA
120 130 140 150 160 170
164 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:38:49 2016 done: Thu Nov 3 17:38:50 2016
Total Scan time: 5.460 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]