Result of FASTA (ccds) for
pFN21AB5154
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5154, 628 aa
1>>>pF1KB5154 628 - 628 aa - 628 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3231+/-0.000839; mu= 11.5444+/- 0.051
mean_var=143.6798+/-29.289, 0's: 0 Z-trim(112.0): 13 B-trim: 5 in 1/51
Lambda= 0.106998
statistics sampled from 12829 (12840) to 12829 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.394), width: 16
Scan time: 4.040
The best scores are: opt bits E(32554)
CCDS6101.1 ASH2L gene_id:9070|Hs108|chr8 ( 628) 4339 681.5 9.1e-196
CCDS47840.1 ASH2L gene_id:9070|Hs108|chr8 ( 534) 3733 587.9 1.2e-167
CCDS64872.1 ASH2L gene_id:9070|Hs108|chr8 ( 489) 3416 538.9 5.8e-153
CCDS59100.1 ASH2L gene_id:9070|Hs108|chr8 ( 501) 3112 492.0 7.9e-139
>>CCDS6101.1 ASH2L gene_id:9070|Hs108|chr8 (628 aa)
initn: 4339 init1: 4339 opt: 4339 Z-score: 3628.1 bits: 681.5 E(32554): 9.1e-196
Smith-Waterman score: 4339; 100.0% identity (100.0% similar) in 628 aa overlap (1-628:1-628)
10 20 30 40 50 60
pF1KB5 MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EGGEANLVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 EGGEANLVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGIC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 TKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 TKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 RTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 DPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 KQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 DCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 DCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 WYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 WYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 GQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 GQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 IIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 IIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWG
550 560 570 580 590 600
610 620
pF1KB5 AVVEHTLADVLYHVETEVDGRRSPPWEP
::::::::::::::::::::::::::::
CCDS61 AVVEHTLADVLYHVETEVDGRRSPPWEP
610 620
>>CCDS47840.1 ASH2L gene_id:9070|Hs108|chr8 (534 aa)
initn: 3733 init1: 3733 opt: 3733 Z-score: 3123.6 bits: 587.9 E(32554): 1.2e-167
Smith-Waterman score: 3733; 100.0% identity (100.0% similar) in 534 aa overlap (95-628:1-534)
70 80 90 100 110 120
pF1KB5 ANLVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWF
::::::::::::::::::::::::::::::
CCDS47 MDTQAGSVDEENGRQLGEVELQCGICTKWF
10 20 30
130 140 150 160 170 180
pF1KB5 TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQD
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB5 EHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB5 KDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB5 GGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 GGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWA
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB5 GKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 GKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB5 ITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGD
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB5 VLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFY
400 410 420 430 440 450
550 560 570 580 590 600
pF1KB5 KNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 KNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVE
460 470 480 490 500 510
610 620
pF1KB5 HTLADVLYHVETEVDGRRSPPWEP
::::::::::::::::::::::::
CCDS47 HTLADVLYHVETEVDGRRSPPWEP
520 530
>>CCDS64872.1 ASH2L gene_id:9070|Hs108|chr8 (489 aa)
initn: 3416 init1: 3416 opt: 3416 Z-score: 2859.6 bits: 538.9 E(32554): 5.8e-153
Smith-Waterman score: 3416; 100.0% identity (100.0% similar) in 489 aa overlap (140-628:1-489)
110 120 130 140 150 160
pF1KB5 LGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMC
::::::::::::::::::::::::::::::
CCDS64 MTNYSFHCNVCHHSGNTYFLRKQANLKEMC
10 20 30
170 180 190 200 210 220
pF1KB5 LSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSK
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 ERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 ERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAA
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 GSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 GSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPD
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 PHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 PHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSM
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 VRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 VRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFH
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB5 QSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 QSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKA
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB5 EKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 EKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDL
400 410 420 430 440 450
590 600 610 620
pF1KB5 TYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP
:::::::::::::::::::::::::::::::::::::::
CCDS64 TYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP
460 470 480
>>CCDS59100.1 ASH2L gene_id:9070|Hs108|chr8 (501 aa)
initn: 3148 init1: 3111 opt: 3112 Z-score: 2605.9 bits: 492.0 E(32554): 7.9e-139
Smith-Waterman score: 3436; 93.8% identity (93.8% similar) in 534 aa overlap (95-628:1-501)
70 80 90 100 110 120
pF1KB5 ANLVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWF
::::::::::::::::::::::::::::::
CCDS59 MDTQAGSVDEENGRQLGEVELQCGICTKWF
10 20 30
130 140 150 160 170 180
pF1KB5 TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 TADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQD
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB5 EHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 EHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB5 KDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 KDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB5 GGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 GGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWA
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB5 GKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 GKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB5 ITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 ITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGD
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB5 VLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 VLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE----
400 410 420 430 440
550 560 570 580 590 600
pF1KB5 KNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVE
:::::::::::::::::::::::::::::::
CCDS59 -----------------------------VSINFGPCFKYPPKDLTYRPMSDMGWGAVVE
450 460 470
610 620
pF1KB5 HTLADVLYHVETEVDGRRSPPWEP
::::::::::::::::::::::::
CCDS59 HTLADVLYHVETEVDGRRSPPWEP
480 490 500
628 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:13:04 2016 done: Thu Nov 3 16:13:04 2016
Total Scan time: 4.040 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]