Result of FASTA (omim) for
pFN21AB5140
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5140, 393 aa
1>>>pF1KB5140 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1363+/-0.00036; mu= 17.0789+/- 0.022
mean_var=63.8292+/-12.880, 0's: 0 Z-trim(113.8): 69 B-trim: 102 in 1/50
Lambda= 0.160533
statistics sampled from 23192 (23271) to 23192 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.273), width: 16
Scan time: 8.660
The best scores are: opt bits E(85289)
NP_004974 (OMIM: 600932) G protein-activated inwar ( 393) 2626 617.1 2.3e-176
XP_016856736 (OMIM: 600932) PREDICTED: G protein-a ( 450) 2626 617.1 2.6e-176
NP_002231 (OMIM: 600877,614098) G protein-activate ( 423) 1845 436.2 6.9e-122
XP_011541111 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1724 408.2 1.9e-113
NP_000881 (OMIM: 600734,613485,613677) G protein-a ( 419) 1724 408.2 1.9e-113
XP_011541112 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1724 408.2 1.9e-113
NP_002230 (OMIM: 601534) G protein-activated inwar ( 501) 1478 351.2 3.1e-96
XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 1323 315.3 1.7e-85
NP_066292 (OMIM: 602323) ATP-sensitive inward rect ( 433) 1323 315.3 1.7e-85
XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 1323 315.3 1.7e-85
NP_001181887 (OMIM: 613236,613239) inward rectifie ( 433) 1306 311.4 2.7e-84
XP_005276976 (OMIM: 613236,613239) PREDICTED: inwa ( 535) 1306 311.4 3.2e-84
NP_000882 (OMIM: 170390,600681,609622,613980) inwa ( 427) 1283 306.0 1.1e-82
NP_001247438 (OMIM: 601534) G protein-activated in ( 308) 1210 289.1 1e-77
NP_037480 (OMIM: 603953) ATP-sensitive inward rect ( 436) 1201 287.1 5.6e-77
NP_000516 (OMIM: 125853,600937,601820,606176,61058 ( 390) 1197 286.1 9.8e-77
XP_005253415 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1142 273.4 7.2e-73
NP_004973 (OMIM: 600935) ATP-sensitive inward rect ( 424) 1142 273.4 7.2e-73
XP_016874772 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1142 273.4 7.2e-73
XP_016874773 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1142 273.4 7.2e-73
NP_722451 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1037 249.0 1.3e-65
NP_722448 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1037 249.0 1.3e-65
NP_722450 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1037 249.0 1.3e-65
NP_722449 (OMIM: 241200,600359) ATP-sensitive inwa ( 389) 1037 249.0 1.4e-65
NP_000211 (OMIM: 241200,600359) ATP-sensitive inwa ( 391) 1037 249.0 1.4e-65
NP_004972 (OMIM: 600504) inward rectifier potassiu ( 445) 1024 246.1 1.3e-64
NP_690607 (OMIM: 600504) inward rectifier potassiu ( 445) 1024 246.1 1.3e-64
NP_001278554 (OMIM: 605722) inward rectifier potas ( 418) 977 235.2 2.3e-61
XP_011523083 (OMIM: 605722) PREDICTED: inward rect ( 418) 977 235.2 2.3e-61
NP_001278553 (OMIM: 605722) inward rectifier potas ( 418) 977 235.2 2.3e-61
NP_001257351 (OMIM: 605722) inward rectifier potas ( 418) 977 235.2 2.3e-61
XP_016880102 (OMIM: 605722) PREDICTED: inward rect ( 418) 977 235.2 2.3e-61
NP_001278552 (OMIM: 605722) inward rectifier potas ( 453) 977 235.2 2.4e-61
NP_061128 (OMIM: 605722) inward rectifier potassiu ( 453) 977 235.2 2.4e-61
XP_016880100 (OMIM: 605722) PREDICTED: inward rect ( 453) 977 235.2 2.4e-61
NP_733937 (OMIM: 605722) inward rectifier potassiu ( 453) 977 235.2 2.4e-61
XP_016880098 (OMIM: 605722) PREDICTED: inward rect ( 453) 977 235.2 2.4e-61
XP_006721948 (OMIM: 605722) PREDICTED: inward rect ( 453) 977 235.2 2.4e-61
XP_006721949 (OMIM: 605722) PREDICTED: inward rect ( 453) 977 235.2 2.4e-61
XP_016880101 (OMIM: 605722) PREDICTED: inward rect ( 453) 977 235.2 2.4e-61
NP_733938 (OMIM: 605722) inward rectifier potassiu ( 453) 977 235.2 2.4e-61
XP_006721950 (OMIM: 605722) PREDICTED: inward rect ( 453) 977 235.2 2.4e-61
NP_001278551 (OMIM: 605722) inward rectifier potas ( 453) 977 235.2 2.4e-61
XP_016880099 (OMIM: 605722) PREDICTED: inward rect ( 453) 977 235.2 2.4e-61
XP_005257394 (OMIM: 605722) PREDICTED: inward rect ( 453) 977 235.2 2.4e-61
XP_016873169 (OMIM: 125853,600937,601820,606176,61 ( 303) 973 234.2 3.3e-61
NP_001159762 (OMIM: 125853,600937,601820,606176,61 ( 303) 973 234.2 3.3e-61
XP_006718289 (OMIM: 125853,600937,601820,606176,61 ( 303) 973 234.2 3.3e-61
NP_002232 (OMIM: 274600,600791,602208,612780) ATP- ( 379) 921 222.2 1.7e-57
NP_001247437 (OMIM: 601534) G protein-activated in ( 235) 897 216.5 5.3e-56
>>NP_004974 (OMIM: 600932) G protein-activated inward re (393 aa)
initn: 2626 init1: 2626 opt: 2626 Z-score: 3287.2 bits: 617.1 E(85289): 2.3e-176
Smith-Waterman score: 2626; 99.7% identity (100.0% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEK
310 320 330 340 350 360
370 380 390
pF1KB5 VEEEGVGEGAGGEAGADKEQNGCLPPPESESKV
:::::.:::::::::::::::::::::::::::
NP_004 VEEEGAGEGAGGEAGADKEQNGCLPPPESESKV
370 380 390
>>XP_016856736 (OMIM: 600932) PREDICTED: G protein-activ (450 aa)
initn: 2626 init1: 2626 opt: 2626 Z-score: 3286.4 bits: 617.1 E(85289): 2.6e-176
Smith-Waterman score: 2626; 99.7% identity (100.0% similar) in 393 aa overlap (1-393:58-450)
10 20 30
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGR
::::::::::::::::::::::::::::::
XP_016 LGAQRRAAGGSSSGPRRTPGARSARPDAAAMAQENAAFSPGQEEPPRRRGRQRYVEKDGR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB5 CNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLE
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB5 HLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVN
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB5 AFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLI
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB5 RSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB5 EIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPT
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB5 PSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGVGEGAGGEAGADKEQNGCLPPPESE
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
XP_016 PSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGGEAGADKEQNGCLPPPESE
390 400 410 420 430 440
pF1KB5 SKV
:::
XP_016 SKV
450
>>NP_002231 (OMIM: 600877,614098) G protein-activated in (423 aa)
initn: 1847 init1: 1820 opt: 1845 Z-score: 2309.2 bits: 436.2 E(85289): 6.9e-122
Smith-Waterman score: 1845; 71.8% identity (89.6% similar) in 376 aa overlap (18-393:50-423)
10 20 30 40
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTD
.: ::::.:::.:::..::::::::::::
NP_002 DVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTD
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB5 LFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGF
.:::::::.::..::.::..:..:::::: ::::::: :::..:.:: .:::::.:::::
NP_002 IFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGF
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB5 VAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKR
:.:::::::::::::::.:::::.:::::.:::.:..:::.::::::::::::::::.::
NP_002 VSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKR
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB5 AATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTD
: :::::.:::.:.:::.:::::::::::.:::::::::::::.:.:: :::::::.:::
NP_002 AETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTD
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB5 LSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTC
..::. ::::::::::::.:::::. ::::: :. : ....:::::::::::::::::
NP_002 INVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTC
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB5 QARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA
::::::...:.:::.::: ::::::::::::: :::::.:. ::: ::.:::: :.: .
NP_002 QARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELASRAEL
320 330 340 350 360 370
350 360 370 380 390
pF1KB5 HLYWSIPSRLDEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV
: ::. :.:....: : : . : . :.:: . :.::::
NP_002 PLSWSVSSKLNQHAELETEEEEKNLE--EQTERNGDVANLENESKV
380 390 400 410 420
>>XP_011541111 (OMIM: 600734,613485,613677) PREDICTED: G (419 aa)
initn: 1719 init1: 1719 opt: 1724 Z-score: 2157.8 bits: 408.2 E(85289): 1.9e-113
Smith-Waterman score: 1725; 70.0% identity (86.6% similar) in 367 aa overlap (18-372:47-411)
10 20 30 40
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTD
.. ::::.::.:.:::..:::.::::::.:
XP_011 VTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSD
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB5 LFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGF
::::::::.::..:: :...:..:::::: ::::::: ::::.:. : : :::.::.::
XP_011 LFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGF
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB5 VAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKR
:.::::::::::::::: ::::..:::::.:::.::::::.::::::::::::::::.::
XP_011 VSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKR
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB5 AATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTD
: ::.::..::.:.:: .:::::::::::.:::::::::::::.:::: :::::::.:::
XP_011 AETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTD
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB5 LSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTC
..::::::::::::::::.:::::. ::::: :. :....::.:::::::::::::::
XP_011 INVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTC
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB5 QARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA
::::::. ::::::::: ::::: ::::::: .::.:.:. :::: :.:::: . ..
XP_011 QARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEM--KREG
320 330 340 350 360 370
350 360 370 380 390
pF1KB5 HLYWSIPSR----------LDEKVE--EEGVGEGAGGEAGADKEQNGCLPPPESESKV
.: .:: :: ..: :: .: ::
XP_011 RLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
380 390 400 410
>>NP_000881 (OMIM: 600734,613485,613677) G protein-activ (419 aa)
initn: 1719 init1: 1719 opt: 1724 Z-score: 2157.8 bits: 408.2 E(85289): 1.9e-113
Smith-Waterman score: 1725; 70.0% identity (86.6% similar) in 367 aa overlap (18-372:47-411)
10 20 30 40
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTD
.. ::::.::.:.:::..:::.::::::.:
NP_000 VTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSD
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB5 LFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGF
::::::::.::..:: :...:..:::::: ::::::: ::::.:. : : :::.::.::
NP_000 LFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGF
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB5 VAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKR
:.::::::::::::::: ::::..:::::.:::.::::::.::::::::::::::::.::
NP_000 VSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKR
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB5 AATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTD
: ::.::..::.:.:: .:::::::::::.:::::::::::::.:::: :::::::.:::
NP_000 AETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTD
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB5 LSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTC
..::::::::::::::::.:::::. ::::: :. :....::.:::::::::::::::
NP_000 INVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTC
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB5 QARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA
::::::. ::::::::: ::::: ::::::: .::.:.:. :::: :.:::: . ..
NP_000 QARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEM--KREG
320 330 340 350 360 370
350 360 370 380 390
pF1KB5 HLYWSIPSR----------LDEKVE--EEGVGEGAGGEAGADKEQNGCLPPPESESKV
.: .:: :: ..: :: .: ::
NP_000 RLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
380 390 400 410
>>XP_011541112 (OMIM: 600734,613485,613677) PREDICTED: G (419 aa)
initn: 1719 init1: 1719 opt: 1724 Z-score: 2157.8 bits: 408.2 E(85289): 1.9e-113
Smith-Waterman score: 1725; 70.0% identity (86.6% similar) in 367 aa overlap (18-372:47-411)
10 20 30 40
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTD
.. ::::.::.:.:::..:::.::::::.:
XP_011 VTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSD
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB5 LFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGF
::::::::.::..:: :...:..:::::: ::::::: ::::.:. : : :::.::.::
XP_011 LFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGF
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB5 VAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKR
:.::::::::::::::: ::::..:::::.:::.::::::.::::::::::::::::.::
XP_011 VSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKR
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB5 AATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTD
: ::.::..::.:.:: .:::::::::::.:::::::::::::.:::: :::::::.:::
XP_011 AETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTD
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB5 LSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTC
..::::::::::::::::.:::::. ::::: :. :....::.:::::::::::::::
XP_011 INVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTC
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB5 QARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA
::::::. ::::::::: ::::: ::::::: .::.:.:. :::: :.:::: . ..
XP_011 QARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEM--KREG
320 330 340 350 360 370
350 360 370 380 390
pF1KB5 HLYWSIPSR----------LDEKVE--EEGVGEGAGGEAGADKEQNGCLPPPESESKV
.: .:: :: ..: :: .: ::
XP_011 RLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
380 390 400 410
>>NP_002230 (OMIM: 601534) G protein-activated inward re (501 aa)
initn: 1509 init1: 1369 opt: 1478 Z-score: 1848.8 bits: 351.2 E(85289): 3.1e-96
Smith-Waterman score: 1478; 63.3% identity (87.7% similar) in 332 aa overlap (10-340:33-363)
10 20 30
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNV-
: :. :... :::.:.:.::::::.::.
NP_002 ALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 RETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWT
:: :::.:::::::::.:: .:..:.:.:...:::....::.::: ::::.. . .:
NP_002 SETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 PCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMF
::: :. .: .:::: ::::.:::::.: :::.:::::.:.:.:.::::.:.::..::::
NP_002 PCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 VKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEG
.:.:::.::: ::.:: :::.:.:::.: ::::::.::.::.: :.:: ::..:::: ::
NP_002 IKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 EFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEG
::.:: : .:.:::.:: :.:::::::.: : ::: :::.. :.:... ..:::::::::
NP_002 EFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 MVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSAREL
.::.::::::::.:: ::::::::: :..::.::..:::..:: ::::::: :..:
NP_002 IVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQ
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 AEAAARLDAHLYWSIPSRLDEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV
:
NP_002 EEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMSS
370 380 390 400 410 420
>>XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensitive i (433 aa)
initn: 1319 init1: 1201 opt: 1323 Z-score: 1655.7 bits: 315.3 E(85289): 1.7e-85
Smith-Waterman score: 1323; 55.3% identity (80.0% similar) in 360 aa overlap (17-369:39-398)
10 20 30 40
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRE-TYRYL
::: :.:.:.:.:.::.. .:. : . :::
XP_011 PYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 TDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLN
.:.::: ::..:: ::.: ::. .::.:: :.:.:: ..:::: : . :::: ...
XP_011 ADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 GFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPN
::.:::::::::.:::::: : .:..:: .. ... :.:.: ....::.: ...:...:.
XP_011 GFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 KRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQ
::: ::.:: .:::.::::.::::.:::.::.:::::: .::.::. : : :::.::: :
XP_011 KRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQ
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 TDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGM
:..:::: : ::.:::::..: :::: :::.. ::. :: ::::::::::::::::.:
XP_011 IDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAM
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 TCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAAR
: :::::::..:.:::::: :: : . :..::. ::.:.::: :: :::..:.:
XP_011 TTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFL
310 320 330 340 350 360
350 360 370 380 390
pF1KB5 LDAHLYWSIPSRL-----DEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV
: . . ..: ::. : .: .:
XP_011 LPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVLEQRPYR
370 380 390 400 410 420
>>NP_066292 (OMIM: 602323) ATP-sensitive inward rectifie (433 aa)
initn: 1319 init1: 1201 opt: 1323 Z-score: 1655.7 bits: 315.3 E(85289): 1.7e-85
Smith-Waterman score: 1323; 55.3% identity (80.0% similar) in 360 aa overlap (17-369:39-398)
10 20 30 40
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRE-TYRYL
::: :.:.:.:.:.::.. .:. : . :::
NP_066 PYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 TDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLN
.:.::: ::..:: ::.: ::. .::.:: :.:.:: ..:::: : . :::: ...
NP_066 ADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 GFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPN
::.:::::::::.:::::: : .:..:: .. ... :.:.: ....::.: ...:...:.
NP_066 GFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 KRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQ
::: ::.:: .:::.::::.::::.:::.::.:::::: .::.::. : : :::.::: :
NP_066 KRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQ
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 TDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGM
:..:::: : ::.:::::..: :::: :::.. ::. :: ::::::::::::::::.:
NP_066 IDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAM
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 TCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAAR
: :::::::..:.:::::: :: : . :..::. ::.:.::: :: :::..:.:
NP_066 TTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFL
310 320 330 340 350 360
350 360 370 380 390
pF1KB5 LDAHLYWSIPSRL-----DEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV
: . . ..: ::. : .: .:
NP_066 LPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVLEQRPYR
370 380 390 400 410 420
>>XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensitive i (433 aa)
initn: 1319 init1: 1201 opt: 1323 Z-score: 1655.7 bits: 315.3 E(85289): 1.7e-85
Smith-Waterman score: 1323; 55.3% identity (80.0% similar) in 360 aa overlap (17-369:39-398)
10 20 30 40
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRE-TYRYL
::: :.:.:.:.:.::.. .:. : . :::
XP_005 PYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB5 TDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLN
.:.::: ::..:: ::.: ::. .::.:: :.:.:: ..:::: : . :::: ...
XP_005 ADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB5 GFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPN
::.:::::::::.:::::: : .:..:: .. ... :.:.: ....::.: ...:...:.
XP_005 GFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 KRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQ
::: ::.:: .:::.::::.::::.:::.::.:::::: .::.::. : : :::.::: :
XP_005 KRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQ
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB5 TDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGM
:..:::: : ::.:::::..: :::: :::.. ::. :: ::::::::::::::::.:
XP_005 IDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAM
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 TCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAAR
: :::::::..:.:::::: :: : . :..::. ::.:.::: :: :::..:.:
XP_005 TTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFL
310 320 330 340 350 360
350 360 370 380 390
pF1KB5 LDAHLYWSIPSRL-----DEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV
: . . ..: ::. : .: .:
XP_005 LPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVLEQRPYR
370 380 390 400 410 420
393 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:10:58 2016 done: Thu Nov 3 16:10:59 2016
Total Scan time: 8.660 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]