Result of FASTA (omim) for
pFN21AB4321
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4321, 1004 aa
1>>>pF1KB4321 1004 - 1004 aa - 1004 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4492+/-0.000669; mu= -0.6574+/- 0.040
mean_var=949.0153+/-213.384, 0's: 0 Z-trim(115.6): 1059 B-trim: 0 in 0/55
Lambda= 0.041633
statistics sampled from 24973 (26197) to 24973 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.307), width: 16
Scan time: 14.090
The best scores are: opt bits E(85289)
NP_001268696 (OMIM: 600004) ephrin type-A receptor (1004) 6820 427.8 1.4e-118
NP_001268694 (OMIM: 600004) ephrin type-A receptor (1038) 6820 427.8 1.4e-118
NP_004430 (OMIM: 600004) ephrin type-A receptor 5 (1037) 6797 426.5 3.7e-118
NP_001305690 (OMIM: 600004) ephrin type-A receptor ( 969) 6343 399.1 5.9e-110
NP_001268695 (OMIM: 600004) ephrin type-A receptor (1016) 4068 262.5 8.1e-69
NP_872272 (OMIM: 600004) ephrin type-A receptor 5 (1015) 4045 261.1 2.1e-68
XP_016861699 (OMIM: 600066) PREDICTED: ephrin type (1104) 3923 253.9 3.5e-66
XP_005265710 (OMIM: 600004) PREDICTED: ephrin type ( 874) 3565 232.2 9.5e-60
XP_011530037 (OMIM: 600004) PREDICTED: ephrin type ( 926) 3561 232.0 1.1e-59
XP_006713655 (OMIM: 600066) PREDICTED: ephrin type (1146) 2641 176.9 5.4e-43
XP_016863370 (OMIM: 600004) PREDICTED: ephrin type ( 817) 2579 172.9 6.2e-42
XP_016863369 (OMIM: 600004) PREDICTED: ephrin type ( 852) 2579 173.0 6.3e-42
XP_016863368 (OMIM: 600004) PREDICTED: ephrin type ( 869) 2579 173.0 6.4e-42
XP_016863367 (OMIM: 600004) PREDICTED: ephrin type ( 904) 2579 173.0 6.5e-42
XP_016861701 (OMIM: 600066) PREDICTED: ephrin type (1012) 2538 170.6 3.7e-41
XP_016861700 (OMIM: 600066) PREDICTED: ephrin type (1018) 2538 170.6 3.8e-41
XP_016861702 (OMIM: 600066) PREDICTED: ephrin type ( 990) 2511 169.0 1.1e-40
NP_872585 (OMIM: 179611) ephrin type-A receptor 3 ( 539) 2456 165.2 8.7e-40
XP_016867305 (OMIM: 600011) PREDICTED: ephrin type (1005) 2401 162.4 1.1e-38
XP_005248728 (OMIM: 602190) PREDICTED: ephrin type ( 610) 2318 157.0 2.9e-37
NP_001073917 (OMIM: 600066) ephrin type-A receptor (1130) 2296 156.2 9.3e-37
NP_065387 (OMIM: 176945) ephrin type-A receptor 8 (1005) 2207 150.7 3.6e-35
XP_005264772 (OMIM: 179611) PREDICTED: ephrin type ( 982) 2057 141.7 1.8e-32
NP_005224 (OMIM: 179611) ephrin type-A receptor 3 ( 983) 2057 141.7 1.8e-32
NP_001275558 (OMIM: 602190) ephrin type-A receptor ( 993) 2004 138.5 1.7e-31
NP_004431 (OMIM: 602190) ephrin type-A receptor 7 ( 998) 2004 138.5 1.7e-31
NP_001291466 (OMIM: 602188) ephrin type-A receptor ( 935) 1984 137.3 3.8e-31
XP_005246431 (OMIM: 602188) PREDICTED: ephrin type ( 949) 1984 137.3 3.8e-31
NP_004429 (OMIM: 602188) ephrin type-A receptor 4 ( 986) 1984 137.3 3.8e-31
NP_001291465 (OMIM: 602188) ephrin type-A receptor ( 986) 1984 137.3 3.8e-31
XP_005264773 (OMIM: 179611) PREDICTED: ephrin type ( 918) 1980 137.0 4.4e-31
XP_016865854 (OMIM: 602190) PREDICTED: ephrin type ( 989) 1969 136.4 7.2e-31
XP_005248726 (OMIM: 602190) PREDICTED: ephrin type ( 994) 1969 136.4 7.2e-31
XP_011539272 (OMIM: 176945) PREDICTED: ephrin type ( 930) 1966 136.2 7.9e-31
XP_011539271 (OMIM: 176945) PREDICTED: ephrin type ( 930) 1966 136.2 7.9e-31
XP_011539275 (OMIM: 176945) PREDICTED: ephrin type ( 930) 1966 136.2 7.9e-31
XP_011539274 (OMIM: 176945) PREDICTED: ephrin type ( 930) 1966 136.2 7.9e-31
XP_016861708 (OMIM: 600066) PREDICTED: ephrin type ( 537) 1925 133.3 3.4e-30
XP_016865855 (OMIM: 602190) PREDICTED: ephrin type ( 442) 1919 132.8 4.1e-30
XP_006710504 (OMIM: 600997,603688) PREDICTED: ephr ( 980) 1896 132.0 1.5e-29
NP_004433 (OMIM: 600997,603688) ephrin type-B rece ( 987) 1896 132.0 1.5e-29
XP_006710505 (OMIM: 600997,603688) PREDICTED: ephr ( 956) 1880 131.1 2.9e-29
NP_059145 (OMIM: 600997,603688) ephrin type-B rece ( 986) 1880 131.1 2.9e-29
NP_001296122 (OMIM: 600997,603688) ephrin type-B r (1055) 1880 131.1 3e-29
NP_001006944 (OMIM: 176945) ephrin type-A receptor ( 495) 1856 129.1 5.9e-29
NP_001296121 (OMIM: 600997,603688) ephrin type-B r ( 928) 1852 129.4 9.1e-29
NP_004434 (OMIM: 601839) ephrin type-B receptor 3 ( 998) 1816 127.3 4.2e-28
NP_004432 (OMIM: 600600) ephrin type-B receptor 1 ( 984) 1793 125.9 1.1e-27
XP_016861357 (OMIM: 600600) PREDICTED: ephrin type (1016) 1793 125.9 1.1e-27
XP_016861356 (OMIM: 600600) PREDICTED: ephrin type (1032) 1793 125.9 1.1e-27
>>NP_001268696 (OMIM: 600004) ephrin type-A receptor 5 i (1004 aa)
initn: 6820 init1: 6820 opt: 6820 Z-score: 2249.8 bits: 427.8 E(85289): 1.4e-118
Smith-Waterman score: 6820; 100.0% identity (100.0% similar) in 1004 aa overlap (1-1004:1-1004)
10 20 30 40 50 60
pF1KB4 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
910 920 930 940 950 960
970 980 990 1000
pF1KB4 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
970 980 990 1000
>>NP_001268694 (OMIM: 600004) ephrin type-A receptor 5 i (1038 aa)
initn: 6820 init1: 6820 opt: 6820 Z-score: 2249.7 bits: 427.8 E(85289): 1.4e-118
Smith-Waterman score: 6820; 100.0% identity (100.0% similar) in 1004 aa overlap (1-1004:1-1004)
10 20 30 40 50 60
pF1KB4 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
910 920 930 940 950 960
970 980 990 1000
pF1KB4 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKI
970 980 990 1000 1010 1020
NP_001 MNSLQEMKVQLVNGMVPL
1030
>>NP_004430 (OMIM: 600004) ephrin type-A receptor 5 isof (1037 aa)
initn: 3876 init1: 3876 opt: 6797 Z-score: 2242.2 bits: 426.5 E(85289): 3.7e-118
Smith-Waterman score: 6797; 99.8% identity (99.8% similar) in 1004 aa overlap (1-1004:1-1003)
10 20 30 40 50 60
pF1KB4 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_004 RARTAAGYGVFSRRFEFETTPV-FAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
550 560 570 580 590
610 620 630 640 650 660
pF1KB4 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB4 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB4 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
900 910 920 930 940 950
970 980 990 1000
pF1KB4 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKI
960 970 980 990 1000 1010
NP_004 MNSLQEMKVQLVNGMVPL
1020 1030
>>NP_001305690 (OMIM: 600004) ephrin type-A receptor 5 i (969 aa)
initn: 6343 init1: 6343 opt: 6343 Z-score: 2095.1 bits: 399.1 E(85289): 5.9e-110
Smith-Waterman score: 6343; 100.0% identity (100.0% similar) in 935 aa overlap (70-1004:1-935)
40 50 60 70 80 90
pF1KB4 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY
::::::::::::::::::::::::::::::
NP_001 MGDLGWIAFPKNGWEEIGEVDENYAPIHTY
10 20 30
100 110 120 130 140 150
pF1KB4 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB4 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB4 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB4 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB4 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB4 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB4 VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIK
400 410 420 430 440 450
520 530 540 550 560 570
pF1KB4 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVS
460 470 480 490 500 510
580 590 600 610 620 630
pF1KB4 VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH
520 530 540 550 560 570
640 650 660 670 680 690
pF1KB4 NGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG
580 590 600 610 620 630
700 710 720 730 740 750
pF1KB4 KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMEN
640 650 660 670 680 690
760 770 780 790 800 810
pF1KB4 GSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSD
700 710 720 730 740 750
820 830 840 850 860 870
pF1KB4 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERP
760 770 780 790 800 810
880 890 900 910 920 930
pF1KB4 YWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRN
820 830 840 850 860 870
940 950 960 970 980 990
pF1KB4 PSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVA
880 890 900 910 920 930
1000
pF1KB4 QVTLE
:::::
NP_001 QVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL
940 950 960
>>NP_001268695 (OMIM: 600004) ephrin type-A receptor 5 i (1016 aa)
initn: 6622 init1: 4057 opt: 4068 Z-score: 1356.5 bits: 262.5 E(85289): 8.1e-69
Smith-Waterman score: 6581; 97.7% identity (97.7% similar) in 1004 aa overlap (1-1004:1-982)
10 20 30 40 50 60
pF1KB4 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGR--
550 560 570 580 590
610 620 630 640 650 660
pF1KB4 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
::::::::::::::::::::::::::::::::::::::::
NP_001 --------------------RCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
600 610 620 630
670 680 690 700 710 720
pF1KB4 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB4 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB4 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB4 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB4 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
880 890 900 910 920 930
970 980 990 1000
pF1KB4 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKI
940 950 960 970 980 990
NP_001 MNSLQEMKVQLVNGMVPL
1000 1010
>>NP_872272 (OMIM: 600004) ephrin type-A receptor 5 isof (1015 aa)
initn: 3873 init1: 3873 opt: 4045 Z-score: 1349.0 bits: 261.1 E(85289): 2.1e-68
Smith-Waterman score: 6558; 97.5% identity (97.5% similar) in 1004 aa overlap (1-1004:1-981)
10 20 30 40 50 60
pF1KB4 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_872 RARTAAGYGVFSRRFEFETTPV-FAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGR--
550 560 570 580 590
610 620 630 640 650 660
pF1KB4 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
::::::::::::::::::::::::::::::::::::::::
NP_872 --------------------RCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
600 610 620 630
670 680 690 700 710 720
pF1KB4 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB4 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB4 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB4 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB4 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
880 890 900 910 920 930
970 980 990 1000
pF1KB4 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
::::::::::::::::::::::::::::::::::::::::::::
NP_872 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKI
940 950 960 970 980 990
NP_872 MNSLQEMKVQLVNGMVPL
1000 1010
>>XP_016861699 (OMIM: 600066) PREDICTED: ephrin type-A r (1104 aa)
initn: 3967 init1: 2078 opt: 3923 Z-score: 1309.1 bits: 253.9 E(85289): 3.5e-66
Smith-Waterman score: 4111; 61.3% identity (82.6% similar) in 969 aa overlap (58-1004:126-1067)
30 40 50 60 70 80
pF1KB4 LAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIG
.:.: :::. ::.:.::: ..: :::. :
XP_016 GGCEVREFLLQFGFFLPLLTAWPGDCSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAIT
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB4 EVDENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTC
:.::. ::::::::.::: :::::: :.::: ..:..:..:.:::::::::.: ::::
XP_016 EMDEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTC
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB4 KETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSK
:::::..:.:::...: ..: ::: ::::::::::::..:::::..:::::.:.:::. .
XP_016 KETFNLFYMESDESHGIKFKPNQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIER
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB4 KGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV
:::::::::.:::::::::::.::::: .::.::.::::: .:::.:.:: ::::. .
XP_016 KGFYLAFQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAE
280 290 300 310 320 330
270 280 290 300 310 320
pF1KB4 TDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSY
. ::..:.:.:.::::.:.:.:..:::: .:.:..:::::.:: .:.::::::
XP_016 ERDTPKLYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSL
340 350 360 370 380 390
330 340 350 360 370 380
pF1KB4 THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK
:. ::.. : ::: ::: :.:::.::::::::::::.. :.:::...::: ::.::::::
XP_016 TYMEATSVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRK
400 410 420 430 440 450
390 400 410 420 430 440
pF1KB4 DVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGV
:..: . ::::. .. ::.::: .:..::..:: :.::...:...:.::::::::.:::
XP_016 DLTYSVICKKCGLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGV
460 470 480 490 500 510
450 460 470 480 490 500
pF1KB4 SDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYF
:.:: . . .....:::.: ::: . :.: ..:::.:::: : :: ::.:::::.
XP_016 SELSFSPKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYY
520 530 540 550 560 570
510 520 530 540 550
pF1KB4 EK-----------------DQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGV
:: .. .:. .:: .. :::::. :::.::.:::.::.
XP_016 EKVYPRIAPAFWHYLRVEEHEQLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSG
580 590 600 610 620 630
560 570 580 590 600
pF1KB4 FSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVV-IGVLLSGSCCECGCGRASS
.:..::::: . ...:.:: :::.... : ::... . :..: :
XP_016 YSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRC----------
640 650 660 670 680
610 620 630 640 650 660
pF1KB4 LCAVAHPSLIWRCGYSKAKQDPEEEKM-HFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFA
: : :::. ::.. :..:::...::..::::: :::::. ::::::
XP_016 ---------QW---YIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFA
690 700 710 720 730
670 680 690 700 710 720
pF1KB4 KEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASI
:::. : : ::::::::::::::::::: :::::.:::::::: :. ..:::::: ::::
XP_016 KEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASI
740 750 760 770 780 790
730 740 750 760 770 780
pF1KB4 MGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAG
::::::::::.::::::::.:::::.:::::::::.::.:.::.:::::::::::::..:
XP_016 MGQFDHPNIIRLEGVVTKSRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASG
800 810 820 830 840 850
790 800 810 820 830 840
pF1KB4 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAP
::::::::::::::::::::.::::::::::::::::::::::::::: :::::::::::
XP_016 MKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAP
860 870 880 890 900 910
850 860 870 880 890 900
pF1KB4 EAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAAL
::::.:::.::::.::::::::::.::::::::::.::::: ..:::::::.:: :::.:
XP_016 EAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASL
920 930 940 950 960 970
910 920 930 940 950 960
pF1KB4 YQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAY
.:::: ::::::: :::: .::..:::::::::.:.:::. . :. .:: :
XP_016 HQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVE-----DILVMPESPGEVPEY
980 990 1000 1010 1020
970 980 990 1000
pF1KB4 R---SVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
.::.::..::::.: . :. :....: .......
XP_016 PLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQ
1030 1040 1050 1060 1070 1080
XP_016 TLRLHMMHIQEKGFHV
1090 1100
>>XP_005265710 (OMIM: 600004) PREDICTED: ephrin type-A r (874 aa)
initn: 3565 init1: 3565 opt: 3565 Z-score: 1193.7 bits: 232.2 E(85289): 9.5e-60
Smith-Waterman score: 5326; 83.7% identity (83.7% similar) in 1004 aa overlap (1-1004:1-840)
10 20 30 40 50 60
pF1KB4 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
:::
XP_005 TCQ---------------------------------------------------------
370 380 390 400 410 420
pF1KB4 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
XP_005 ------------------------------------------------------------
430 440 450 460 470 480
pF1KB4 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
:::::::::::::
XP_005 -----------------------------------------------APSPVTNVKKGKI
310
490 500 510 520 530 540
pF1KB4 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
320 330 340 350 360 370
550 560 570 580 590 600
pF1KB4 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
380 390 400 410 420 430
610 620 630 640 650 660
pF1KB4 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
440 450 460 470 480 490
670 680 690 700 710 720
pF1KB4 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
500 510 520 530 540 550
730 740 750 760 770 780
pF1KB4 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
560 570 580 590 600 610
790 800 810 820 830 840
pF1KB4 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
620 630 640 650 660 670
850 860 870 880 890 900
pF1KB4 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
680 690 700 710 720 730
910 920 930 940 950 960
pF1KB4 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
740 750 760 770 780 790
970 980 990 1000
pF1KB4 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKI
800 810 820 830 840 850
XP_005 MNSLQEMKVQLVNGMVPL
860 870
>>XP_011530037 (OMIM: 600004) PREDICTED: ephrin type-A r (926 aa)
initn: 6091 init1: 3560 opt: 3561 Z-score: 1192.2 bits: 232.0 E(85289): 1.1e-59
Smith-Waterman score: 5822; 88.7% identity (88.8% similar) in 1004 aa overlap (1-1004:1-892)
10 20 30 40 50 60
pF1KB4 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACT-----
310 320 330 340 350
370 380 390 400 410 420
pF1KB4 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
XP_011 ------------------------------------------------------------
430 440 450 460 470 480
pF1KB4 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
.::::::::::::
XP_011 -----------------------------------------------TPSPVTNVKKGKI
360
490 500 510 520 530 540
pF1KB4 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
370 380 390 400 410 420
550 560 570 580 590 600
pF1KB4 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCC
430 440 450 460 470 480
610 620 630 640 650 660
pF1KB4 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDP
490 500 510 520 530 540
670 680 690 700 710 720
pF1KB4 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRR
550 560 570 580 590 600
730 740 750 760 770 780
pF1KB4 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVG
610 620 630 640 650 660
790 800 810 820 830 840
pF1KB4 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGK
670 680 690 700 710 720
850 860 870 880 890 900
pF1KB4 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPS
730 740 750 760 770 780
910 920 930 940 950 960
pF1KB4 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEH
790 800 810 820 830 840
970 980 990 1000
pF1KB4 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE
::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKI
850 860 870 880 890 900
XP_011 MNSLQEMKVQLVNGMVPL
910 920
>>XP_006713655 (OMIM: 600066) PREDICTED: ephrin type-A r (1146 aa)
initn: 3361 init1: 2078 opt: 2641 Z-score: 892.8 bits: 176.9 E(85289): 5.4e-43
Smith-Waterman score: 4004; 58.9% identity (79.0% similar) in 1006 aa overlap (58-999:126-1104)
30 40 50 60 70 80
pF1KB4 LAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIG
.:.: :::. ::.:.::: ..: :::. :
XP_006 GGCEVREFLLQFGFFLPLLTAWPGDCSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAIT
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB4 EVDENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTC
:.::. ::::::::.::: :::::: :.::: ..:..:..:.:::::::::.: ::::
XP_006 EMDEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTC
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB4 KETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSK
:::::..:.:::...: ..: ::: ::::::::::::..:::::..:::::.:.:::. .
XP_006 KETFNLFYMESDESHGIKFKPNQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIER
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB4 KGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV
:::::::::.:::::::::::.::::: .::.::.::::: .:::.:.:: ::::. .
XP_006 KGFYLAFQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAE
280 290 300 310 320 330
270 280 290 300 310 320
pF1KB4 TDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSY
. ::..:.:.:.::::.:.:.:..:::: .:.:..:::::.:: .:.::::::
XP_006 ERDTPKLYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSL
340 350 360 370 380 390
330 340 350 360 370 380
pF1KB4 THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK
:. ::.. : ::: ::: :.:::.::::::::::::.. :.:::...::: ::.::::::
XP_006 TYMEATSVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRK
400 410 420 430 440 450
390 400 410 420 430 440
pF1KB4 DVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGV
:..: . ::::. .. ::.::: .:..::..:: :.::...:...:.::::::::.:::
XP_006 DLTYSVICKKCGLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGV
460 470 480 490 500 510
450 460 470 480 490 500
pF1KB4 SDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYF
:.:: . . .....:::.: ::: . :.: ..:::.:::: : :: ::.:::::.
XP_006 SELSFSPKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYY
520 530 540 550 560 570
510 520 530 540 550
pF1KB4 EK-----------------DQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGV
:: .. .:. .:: .. :::::. :::.::.:::.::.
XP_006 EKVYPRIAPAFWHYLRVEEHEQLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSG
580 590 600 610 620 630
560 570 580 590 600
pF1KB4 FSRRFEFETTPVSVAASSDQSQIPVIAVSVTVGVILLAVV-IGVLLSGSCCECGCGRASS
.:..::::: . ...:.:: :::.... : ::... . :..: :
XP_006 YSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQ---------
640 650 660 670 680
610 620 630 640 650 660
pF1KB4 LCAVAHPSLIWRCGYSKAKQDPEEEKM-HFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFA
: : :::. ::.. :..:::...::..::::: :::::. ::::::
XP_006 ----------W---YIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFA
690 700 710 720 730
670 680 690 700 710 720
pF1KB4 KEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASI
:::. : : ::::::::::::::::::: :::::.:::::::: :. ..:::::: ::::
XP_006 KEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASI
740 750 760 770 780 790
730 740
pF1KB4 MGQFDHPNIIHLEGVVTK------------------------------------------
::::::::::.:::::::
XP_006 MGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPA
800 810 820 830 840 850
750 760 770 780 790 800
pF1KB4 SKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARN
..:::::.:::::::::.::.:.::.:::::::::::::..:::::::::::::::::::
XP_006 GRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARN
860 870 880 890 900 910
810 820 830 840 850 860
pF1KB4 ILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYG
::.::::::::::::::::::::::::::: :::::::::::::::.:::.::::.::::
XP_006 ILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYG
920 930 940 950 960 970
870 880 890 900 910 920
pF1KB4 IVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKF
::::::.::::::::::.::::: ..:::::::.:: :::.:.:::: ::::::: ::::
XP_006 IVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKF
980 990 1000 1010 1020 1030
930 940 950 960 970 980
pF1KB4 DEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYR---SVGEWLEAIKMGRY
.::..:::::::::.:.:::. . :. .:: : .::.::..::::.:
XP_006 TDIVSFLDKLIRNPSALHTLVE-----DILVMPESPGEVPEYPLFVTVGDWLDSIKMGQY
1040 1050 1060 1070 1080
990 1000
pF1KB4 TEIFMENGYSSMDAVAQVTLE
. :. :....: ..
XP_006 KNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
1090 1100 1110 1120 1130 1140
1004 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:44:41 2016 done: Thu Nov 3 14:44:43 2016
Total Scan time: 14.090 Total Display time: 0.480
Function used was FASTA [36.3.4 Apr, 2011]