Result of FASTA (omim) for
pFN21AB3626
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3626, 1154 aa
1>>>pF1KB3626 1154 - 1154 aa - 1154 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.9206+/-0.000656; mu= -26.7634+/- 0.039
mean_var=933.4235+/-214.539, 0's: 0 Z-trim(111.8): 1153 B-trim: 1130 in 1/59
Lambda= 0.041979
statistics sampled from 19263 (20531) to 19263 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.241), width: 16
Scan time: 14.000
The best scores are: opt bits E(85289)
NP_001308784 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308785 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308782 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_002218 (OMIM: 147795) tyrosine-protein kinase J (1154) 7820 492.1 8.4e-138
NP_001307852 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308781 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308783 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308786 (OMIM: 147795) tyrosine-protein kinas (1153) 7801 490.9 1.9e-137
XP_016856701 (OMIM: 147795) PREDICTED: tyrosine-pr (1153) 7801 490.9 1.9e-137
XP_011526551 (OMIM: 176941,611521) PREDICTED: non- ( 745) 2131 147.3 3.3e-34
XP_011526549 (OMIM: 176941,611521) PREDICTED: non- (1088) 2131 147.5 4.2e-34
XP_011526548 (OMIM: 176941,611521) PREDICTED: non- (1088) 2131 147.5 4.2e-34
XP_011526553 (OMIM: 176941,611521) PREDICTED: non- ( 606) 2122 146.6 4.3e-34
XP_011526547 (OMIM: 176941,611521) PREDICTED: non- (1187) 2131 147.6 4.5e-34
NP_003322 (OMIM: 176941,611521) non-receptor tyros (1187) 2131 147.6 4.5e-34
XP_011526292 (OMIM: 600173,600802) PREDICTED: tyro ( 866) 1283 96.0 1.1e-18
NP_001309128 (OMIM: 133100,147796,254450,263300,60 ( 727) 1119 86.0 9.2e-16
NP_001309127 (OMIM: 133100,147796,254450,263300,60 ( 727) 1119 86.0 9.2e-16
NP_001309133 (OMIM: 133100,147796,254450,263300,60 ( 983) 1119 86.2 1.1e-15
NP_001309123 (OMIM: 133100,147796,254450,263300,60 (1132) 1119 86.2 1.2e-15
NP_001309125 (OMIM: 133100,147796,254450,263300,60 (1132) 1119 86.2 1.2e-15
NP_004963 (OMIM: 133100,147796,254450,263300,60088 (1132) 1119 86.2 1.2e-15
NP_001309124 (OMIM: 133100,147796,254450,263300,60 (1132) 1119 86.2 1.2e-15
NP_000206 (OMIM: 600173,600802) tyrosine-protein k (1124) 1039 81.4 3.5e-14
XP_005259953 (OMIM: 600173,600802) PREDICTED: tyro (1167) 1039 81.4 3.6e-14
XP_011526293 (OMIM: 600173,600802) PREDICTED: tyro ( 650) 658 58.0 2.2e-07
XP_011526554 (OMIM: 176941,611521) PREDICTED: non- ( 606) 639 56.8 4.6e-07
XP_011533958 (OMIM: 606573) PREDICTED: tyrosine-pr ( 392) 521 49.5 5e-05
XP_005266939 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 521 49.6 5.9e-05
XP_011533955 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 521 49.6 5.9e-05
XP_016866134 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 521 49.6 5.9e-05
XP_011533956 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 521 49.6 5.9e-05
XP_011533957 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 521 49.6 5.9e-05
XP_005266938 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 521 49.6 5.9e-05
NP_002022 (OMIM: 606573) tyrosine-protein kinase F ( 505) 521 49.6 5.9e-05
XP_005266937 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 521 49.6 5.9e-05
XP_016859071 (OMIM: 600543,615515) PREDICTED: rece (1116) 502 48.9 0.00021
XP_005246434 (OMIM: 600543,615515) PREDICTED: rece (1282) 502 48.9 0.00023
NP_001036064 (OMIM: 600543,615515) receptor tyrosi (1292) 502 48.9 0.00023
XP_005246433 (OMIM: 600543,615515) PREDICTED: rece (1298) 502 48.9 0.00024
NP_005226 (OMIM: 600543,615515) receptor tyrosine- (1308) 502 49.0 0.00024
XP_016859070 (OMIM: 600543,615515) PREDICTED: rece (1318) 502 49.0 0.00024
XP_006712427 (OMIM: 600543,615515) PREDICTED: rece (1323) 502 49.0 0.00024
XP_016859069 (OMIM: 600543,615515) PREDICTED: rece (1324) 502 49.0 0.00024
XP_016859068 (OMIM: 600543,615515) PREDICTED: rece (1333) 502 49.0 0.00024
XP_016859067 (OMIM: 600543,615515) PREDICTED: rece (1334) 502 49.0 0.00024
XP_016859066 (OMIM: 600543,615515) PREDICTED: rece (1349) 502 49.0 0.00024
XP_011510623 (OMIM: 606994) PREDICTED: activated C ( 979) 486 47.8 0.00039
NP_005772 (OMIM: 606994) activated CDC42 kinase 1 (1038) 486 47.9 0.0004
NP_001294975 (OMIM: 606994) activated CDC42 kinase (1040) 486 47.9 0.0004
>>NP_001308784 (OMIM: 147795) tyrosine-protein kinase JA (1154 aa)
initn: 7820 init1: 7820 opt: 7820 Z-score: 2595.0 bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1090 1100 1110 1120 1130 1140
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
NP_001 SFQNLIEGFEALLK
1150
>>NP_001308785 (OMIM: 147795) tyrosine-protein kinase JA (1154 aa)
initn: 7820 init1: 7820 opt: 7820 Z-score: 2595.0 bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1090 1100 1110 1120 1130 1140
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
NP_001 SFQNLIEGFEALLK
1150
>>NP_001308782 (OMIM: 147795) tyrosine-protein kinase JA (1154 aa)
initn: 7820 init1: 7820 opt: 7820 Z-score: 2595.0 bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1090 1100 1110 1120 1130 1140
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
NP_001 SFQNLIEGFEALLK
1150
>>NP_002218 (OMIM: 147795) tyrosine-protein kinase JAK1 (1154 aa)
initn: 7820 init1: 7820 opt: 7820 Z-score: 2595.0 bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1090 1100 1110 1120 1130 1140
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
NP_002 SFQNLIEGFEALLK
1150
>>NP_001307852 (OMIM: 147795) tyrosine-protein kinase JA (1154 aa)
initn: 7820 init1: 7820 opt: 7820 Z-score: 2595.0 bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1090 1100 1110 1120 1130 1140
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
NP_001 SFQNLIEGFEALLK
1150
>>NP_001308781 (OMIM: 147795) tyrosine-protein kinase JA (1154 aa)
initn: 7820 init1: 7820 opt: 7820 Z-score: 2595.0 bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1090 1100 1110 1120 1130 1140
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
NP_001 SFQNLIEGFEALLK
1150
>>NP_001308783 (OMIM: 147795) tyrosine-protein kinase JA (1154 aa)
initn: 7820 init1: 7820 opt: 7820 Z-score: 2595.0 bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1090 1100 1110 1120 1130 1140
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
NP_001 SFQNLIEGFEALLK
1150
>>NP_001308786 (OMIM: 147795) tyrosine-protein kinase JA (1153 aa)
initn: 4536 init1: 4536 opt: 7801 Z-score: 2588.8 bits: 490.9 E(85289): 1.9e-137
Smith-Waterman score: 7801; 99.9% identity (99.9% similar) in 1154 aa overlap (1-1154:1-1153)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSE-VQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1080 1090 1100 1110 1120 1130
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
NP_001 SFQNLIEGFEALLK
1140 1150
>>XP_016856701 (OMIM: 147795) PREDICTED: tyrosine-protei (1153 aa)
initn: 4536 init1: 4536 opt: 7801 Z-score: 2588.8 bits: 490.9 E(85289): 1.9e-137
Smith-Waterman score: 7801; 99.9% identity (99.9% similar) in 1154 aa overlap (1-1154:1-1153)
10 20 30 40 50 60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFEKSE-VQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
490 500 510 520 530
550 560 570 580 590 600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
1080 1090 1100 1110 1120 1130
1150
pF1KB3 SFQNLIEGFEALLK
::::::::::::::
XP_016 SFQNLIEGFEALLK
1140 1150
>>XP_011526551 (OMIM: 176941,611521) PREDICTED: non-rece (745 aa)
initn: 1398 init1: 1121 opt: 2131 Z-score: 735.1 bits: 147.3 E(85289): 3.3e-34
Smith-Waterman score: 2451; 50.6% identity (76.3% similar) in 735 aa overlap (429-1146:3-724)
400 410 420 430 440 450
pF1KB3 HEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGS
::: . .: : . .. :::
XP_011 MLPPLQA----AACAGNL-EPFVQAKLRP---
10 20
460 470 480 490 500 510
pF1KB3 EEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQK-QFKNFQIEVQKGRYSLHGSDRSFP
:.:.:...:: . ...::. ..:. .: :. ....: :: : : . :.: ::::
XP_011 EDGLYLIHWSTSHPYRLILTVA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFP
30 40 50 60 70 80
520 530 540 550 560 570
pF1KB3 SLGDLMSHLKKQILRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDR
:. .: . :. .::. . : :.::: :.: : :::.. . :. . .::::: :
XP_011 SVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM-RGARASPRTLNLSQLSFHR
90 100 110 120 130 140
580 590 600 610 620
pF1KB3 ILKKDLVQGEHLGRGTRTHIYSGTL------------MDYKDD--EGTSEEKKIKVILKV
. .:...: :::.::::..: : : :: .: : .. ....:.:::
XP_011 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV
150 160 170 180 190 200
630 640 650 660 670 680
pF1KB3 LDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKS
:::::.::.:::.:.::.: :::: :.....::::: ::::: :.:: ::::....:.
XP_011 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER
210 220 230 240 250 260
690 700 710 720 730 740
pF1KB3 DVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIP
. ::. ::.::::::::::.:.::::::: .:.:::: :. .:::::::::.
XP_011 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG
270 280 290 300 310 320
750 760 770 780 790 800
pF1KB3 ITVLSRQECIERIPWIAPECVEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDKTLIEK
. .:::.: .:::::.::::. . : ::.: :::.::.:: :::..:: ::.... ::
XP_011 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK
330 340 350 360 370 380
810 820 830 840 850 860
pF1KB3 ERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQN-PDIVSEKKP
:.::. . : ::: .:: : ..:..:.:.::: ::.:.::...:. .: :... .
XP_011 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD
390 400 410 420 430 440
870 880 890 900 910 920
pF1KB3 ATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIAD
. ::: :.::.::.:::::::::::: : ::: .:.:::.::::.:: . : .: .
XP_011 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG
450 460 470 480 490 500
930 940 950 960 970 980
pF1KB3 LKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQL
:.::.:::.::::.:.:::: : ..: ....:.::..: :::..:::... :.: : :
XP_011 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLL
510 520 530 540 550
990 1000 1010 1020 1030 1040
pF1KB3 KYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDR
.: :::.:: :: ...:.::::::::::..... ::::::::.::. .::: :..:
XP_011 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG
560 570 580 590 600 610
1050 1060 1070 1080 1090 1100
pF1KB3 DSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTV
:::::::::::: . ::: :::::::::::.::::.:::..:: . ::..:: ..:::::
XP_011 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV
620 630 640 650 660 670
1110 1120 1130 1140 1150
pF1KB3 TRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK
::.. :..:.::: : .:: :::.::..::: . : : .:.:::
XP_011 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP
680 690 700 710 720 730
XP_011 SVFSVC
740
1154 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:32:30 2016 done: Thu Nov 3 13:32:32 2016
Total Scan time: 14.000 Total Display time: 0.530
Function used was FASTA [36.3.4 Apr, 2011]