Result of FASTA (omim) for
pFN21AB3492
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3492, 397 aa
1>>>pF1KB3492 397 - 397 aa - 397 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7026+/-0.000408; mu= 14.2790+/- 0.025
mean_var=60.8622+/-12.346, 0's: 0 Z-trim(109.9): 49 B-trim: 873 in 1/57
Lambda= 0.164399
statistics sampled from 18137 (18168) to 18137 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.561), E-opt: 0.2 (0.213), width: 16
Scan time: 7.700
The best scores are: opt bits E(85289)
NP_005882 (OMIM: 100678,614055) acetyl-CoA acetylt ( 397) 2583 621.5 1.1e-177
NP_001290182 (OMIM: 100678,614055) acetyl-CoA acet ( 426) 2469 594.4 1.6e-169
NP_000010 (OMIM: 203750,607809) acetyl-CoA acetylt ( 427) 1030 253.1 9e-67
NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, ( 397) 1001 246.3 9.9e-65
XP_006718898 (OMIM: 203750,607809) PREDICTED: acet ( 337) 897 221.6 2.3e-57
XP_016873170 (OMIM: 203750,607809) PREDICTED: acet ( 337) 897 221.6 2.3e-57
NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, ( 424) 841 208.3 2.8e-53
XP_016873171 (OMIM: 203750,607809) PREDICTED: acet ( 301) 723 180.3 5.4e-45
XP_016873172 (OMIM: 203750,607809) PREDICTED: acet ( 301) 723 180.3 5.4e-45
XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 272) 699 174.6 2.5e-43
XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 279) 699 174.6 2.6e-43
NP_001123882 (OMIM: 604054) 3-ketoacyl-CoA thiolas ( 331) 350 91.8 2.5e-18
XP_006713185 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 364) 350 91.9 2.8e-18
NP_001268442 (OMIM: 143450,609015) trifunctional e ( 452) 199 56.1 2e-07
NP_000174 (OMIM: 143450,609015) trifunctional enzy ( 474) 199 56.1 2.1e-07
XP_011531105 (OMIM: 143450,609015) PREDICTED: trif ( 474) 199 56.1 2.1e-07
XP_016859428 (OMIM: 143450,609015) PREDICTED: trif ( 481) 199 56.1 2.2e-07
NP_001268441 (OMIM: 143450,609015) trifunctional e ( 459) 180 51.6 4.7e-06
>>NP_005882 (OMIM: 100678,614055) acetyl-CoA acetyltrans (397 aa)
initn: 2583 init1: 2583 opt: 2583 Z-score: 3310.9 bits: 621.5 E(85289): 1.1e-177
Smith-Waterman score: 2583; 99.7% identity (100.0% similar) in 397 aa overlap (1-397:1-397)
10 20 30 40 50 60
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLT
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_005 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC
310 320 330 340 350 360
370 380 390
pF1KB3 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
:::::::::::::::::::::::::::::::::::::
NP_005 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
370 380 390
>>NP_001290182 (OMIM: 100678,614055) acetyl-CoA acetyltr (426 aa)
initn: 2468 init1: 2468 opt: 2469 Z-score: 3164.3 bits: 594.4 E(85289): 1.6e-169
Smith-Waterman score: 2469; 98.7% identity (99.2% similar) in 384 aa overlap (14-397:43-426)
10 20 30 40
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLK
:.: ::::::::::::::::::::::::
NP_001 RRATAASLGRSGGRLSSPRLLRVVAPTLTFAQTSRCSFNGALAAVPVQDLGSTVIKEVLK
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB3 RATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAV
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB3 QSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGIT
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB3 AENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDEFPR
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 AENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPR
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB3 HGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSW
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB3 SQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVN
320 330 340 350 360 370
350 360 370 380 390
pF1KB3 IEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
380 390 400 410 420
>>NP_000010 (OMIM: 203750,607809) acetyl-CoA acetyltrans (427 aa)
initn: 993 init1: 395 opt: 1030 Z-score: 1319.8 bits: 253.1 E(85289): 9e-67
Smith-Waterman score: 1030; 43.8% identity (74.4% similar) in 390 aa overlap (8-396:42-426)
10 20 30
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTV
::::::.:: :::: :.:. .:. ::: .
NP_000 ARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 IKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLK
:. ....: . :.:.:. .:.:: .: :: :.::: .:::.: :.: . . .:.::.:
NP_000 IQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 AVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHN
:. .: ::. : ....::::::.::..:.. : .. : . : : :. :::::....
NP_000 AIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKLEDLIVKDGLTDVYNK
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB3 CHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTR-RGLIEV
::: :::.::: ...:..:: :. : .:.. : .::.: .:..:: :... . . :
NP_000 IHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVV
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB3 KTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTP
: :: .. .. . ::: : .. :::: :::: .::::::.::: . : . ..::
NP_000 KEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAALVLMTADAAKRLNVTP
260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELG
:::::......::: . :.:. : .... .: . ::. ..:.::::. : : .: :
NP_000 LARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 LNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQR
..:.::::.:::..::::.: :: ::. : :.: ..:. :.:..: ::: . :: .:.
NP_000 IDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLASICNGGGGASAMLIQK
370 380 390 400 410 420
pF1KB3 E
NP_000 L
>>NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, mito (397 aa)
initn: 1023 init1: 534 opt: 1001 Z-score: 1283.1 bits: 246.3 E(85289): 9.9e-65
Smith-Waterman score: 1001; 42.7% identity (72.1% similar) in 391 aa overlap (8-395:7-394)
10 20 30 40 50 60
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
: .:.: :: .:...: : . ::. . : .:. . :.:: :. ::.:.:
NP_006 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNV
10 20 30 40 50
70 80 90 100 110
pF1KB3 LAAGCGQNPV-RQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGM
: .. . :.... .::: .:: . . .::::.... . : : . .. .:. ::
NP_006 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 ENMSKAPHLAY-LRTGVKIG-EMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSRED
:.::.::. . .: :.:.: .. : ::. . ::: . :..::::.: : ..:::.
NP_006 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 QDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDEFPRHGSNIEAMSKLKPY
:: :. ::.: . :. ::.:. :..:. :.:..: ...:: : ...: ..:: :
NP_006 CDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 FLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGP
: ::: :: .::::. :::.::.. ... . :...:::::::.. : .::::::::
NP_006 FKKDGT--VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 IPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGA
.:::. :. ::: ::.:.:. :.::::: :. . : :. :.:..:::::::::::.
NP_006 VPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGG
300 310 320 330 340 350
360 370 380 390
pF1KB3 SGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
:: :: . :.: :.: : . .:.. :::::.:::. .:
NP_006 SGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
360 370 380 390
>>XP_006718898 (OMIM: 203750,607809) PREDICTED: acetyl-C (337 aa)
initn: 860 init1: 395 opt: 897 Z-score: 1151.0 bits: 221.6 E(85289): 2.3e-57
Smith-Waterman score: 897; 43.5% identity (73.8% similar) in 340 aa overlap (58-396:2-336)
30 40 50 60 70 80
pF1KB3 VPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWS
:.:: .: :: :.::: .:::.: :.: .
XP_006 MGNVLQGGEGQAPTRQAVLGAGLPISTPCTT
10 20 30
90 100 110 120 130 140
pF1KB3 CQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSIL
. .:.::.::. .: ::. : ....::::::.::..:.. : .. : . : : :.
XP_006 INKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKLEDLIV
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB3 CDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLV
:::::.... ::: :::.::: ...:..:: :. : .:.. : .::.: .:..:: :
XP_006 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB3 STR-RGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKK
... . . :: :: .. .. . ::: : .. :::: :::: .::::::.:::
XP_006 TVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAALVLMTA
160 170 180 190 200
270 280 290 300 310 320
pF1KB3 SEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAA
. : . ..:::::::......::: . :.:. : .... .: . ::. ..:.::::.
XP_006 DAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSL
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB3 VSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGG
: : .: : ..:.::::.:::..::::.: :: ::. : :.: ..:. :.:..: ::
XP_006 VVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLASICNGG
270 280 290 300 310 320
390
pF1KB3 GMGIAMCVQRE
: . :: .:.
XP_006 GGASAMLIQKL
330
>>XP_016873170 (OMIM: 203750,607809) PREDICTED: acetyl-C (337 aa)
initn: 860 init1: 395 opt: 897 Z-score: 1151.0 bits: 221.6 E(85289): 2.3e-57
Smith-Waterman score: 897; 43.5% identity (73.8% similar) in 340 aa overlap (58-396:2-336)
30 40 50 60 70 80
pF1KB3 VPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWS
:.:: .: :: :.::: .:::.: :.: .
XP_016 MGNVLQGGEGQAPTRQAVLGAGLPISTPCTT
10 20 30
90 100 110 120 130 140
pF1KB3 CQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSIL
. .:.::.::. .: ::. : ....::::::.::..:.. : .. : . : : :.
XP_016 INKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKLEDLIV
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB3 CDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLV
:::::.... ::: :::.::: ...:..:: :. : .:.. : .::.: .:..:: :
XP_016 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB3 STR-RGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKK
... . . :: :: .. .. . ::: : .. :::: :::: .::::::.:::
XP_016 TVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAALVLMTA
160 170 180 190 200
270 280 290 300 310 320
pF1KB3 SEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAA
. : . ..:::::::......::: . :.:. : .... .: . ::. ..:.::::.
XP_016 DAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSL
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB3 VSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGG
: : .: : ..:.::::.:::..::::.: :: ::. : :.: ..:. :.:..: ::
XP_016 VVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLASICNGG
270 280 290 300 310 320
390
pF1KB3 GMGIAMCVQRE
: . :: .:.
XP_016 GGASAMLIQKL
330
>>NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, pero (424 aa)
initn: 817 init1: 414 opt: 841 Z-score: 1077.5 bits: 208.3 E(85289): 2.8e-53
Smith-Waterman score: 841; 41.6% identity (66.4% similar) in 399 aa overlap (3-391:33-416)
10 20 30
pF1KB3 MNAGSDPVVIVSAARTIIGSFN-GALAAVPVQ
:.. ::.: . :: : . :.. . .
NP_001 RLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 DLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMI
.: :.:. ::: ... ::..... :.:: : : .: :. . :: .:: . .
NP_001 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 CGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGL
:.:::.:: . .: :. .: .: :.:.:: : . :. : : .
NP_001 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR----------GNPGNITSRLME--
130 140 150 160 170
160 170 180 190 200
pF1KB3 TDAFHNC--HMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVS-
. ..: ::::.::::... .::: :: :. ::... ::. : :. ::::: ..
NP_001 KEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTV
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB3 -----TRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVL
:.:. : : :: : ....:...:::: : :: ..: .:.: ..:::::..:
NP_001 HDDKGTKRS-ITVTQDEGIRPSTTMEGLAKLKPAFKKDG--STTAGNSSQVSDGAAAILL
240 250 260 270 280
270 280 290 300 310 320
pF1KB3 MKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEA
..:.:.. :: :. . :.. ::: :.:::::: :: :. ::: .. ::::::::::
NP_001 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB3 FAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAAL
::. .: :..: : ::::: :::.::::::: .: : ..:::. :.: : :. ::...
NP_001 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
350 360 370 380 390 400
390
pF1KB3 CIGGGMGIAMCVQRE
::: ::: :
NP_001 CIGTGMGAAAVFEYPGN
410 420
>>XP_016873171 (OMIM: 203750,607809) PREDICTED: acetyl-C (301 aa)
initn: 686 init1: 395 opt: 723 Z-score: 928.8 bits: 180.3 E(85289): 5.4e-45
Smith-Waterman score: 723; 43.2% identity (73.7% similar) in 285 aa overlap (113-396:21-300)
90 100 110 120 130 140
pF1KB3 VPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPL
..::::::.::..:.. : .. : . :
XP_016 MFYKEVKDKLLQGRQYWVQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKL
10 20 30 40
150 160 170 180 190 200
pF1KB3 TDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEI
: :. :::::.... ::: :::.::: ...:..:: :. : .:.. : .::.: .:.
XP_016 EDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEV
50 60 70 80 90 100
210 220 230 240 250 260
pF1KB3 VPVLVSTR-RGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAV
.:: :... . . :: :: .. .. . ::: : .. :::: :::: .::::::.
XP_016 IPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAAL
110 120 130 140 150 160
270 280 290 300 310 320
pF1KB3 VLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEIN
::: . : . ..:::::::......::: . :.:. : .... .: . ::. ..:.:
XP_016 VLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVN
170 180 190 200 210 220
330 340 350 360 370 380
pF1KB3 EAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAA
:::. : : .: : ..:.::::.:::..::::.: :: ::. : :.: ..:. :.:.
XP_016 EAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLAS
230 240 250 260 270 280
390
pF1KB3 LCIGGGMGIAMCVQRE
.: ::: . :: .:.
XP_016 ICNGGGGASAMLIQKL
290 300
>>XP_016873172 (OMIM: 203750,607809) PREDICTED: acetyl-C (301 aa)
initn: 686 init1: 395 opt: 723 Z-score: 928.8 bits: 180.3 E(85289): 5.4e-45
Smith-Waterman score: 723; 43.2% identity (73.7% similar) in 285 aa overlap (113-396:21-300)
90 100 110 120 130 140
pF1KB3 VPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPL
..::::::.::..:.. : .. : . :
XP_016 MFYKEVKDKLLQGRQYWVQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKL
10 20 30 40
150 160 170 180 190 200
pF1KB3 TDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEI
: :. :::::.... ::: :::.::: ...:..:: :. : .:.. : .::.: .:.
XP_016 EDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEV
50 60 70 80 90 100
210 220 230 240 250 260
pF1KB3 VPVLVSTR-RGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAV
.:: :... . . :: :: .. .. . ::: : .. :::: :::: .::::::.
XP_016 IPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAAL
110 120 130 140 150 160
270 280 290 300 310 320
pF1KB3 VLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEIN
::: . : . ..:::::::......::: . :.:. : .... .: . ::. ..:.:
XP_016 VLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVN
170 180 190 200 210 220
330 340 350 360 370 380
pF1KB3 EAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAA
:::. : : .: : ..:.::::.:::..::::.: :: ::. : :.: ..:. :.:.
XP_016 EAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLAS
230 240 250 260 270 280
390
pF1KB3 LCIGGGMGIAMCVQRE
.: ::: . :: .:.
XP_016 ICNGGGGASAMLIQKL
290 300
>>XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA (272 aa)
initn: 674 init1: 414 opt: 699 Z-score: 898.8 bits: 174.6 E(85289): 2.5e-43
Smith-Waterman score: 699; 50.2% identity (74.1% similar) in 239 aa overlap (160-391:29-264)
130 140 150 160 170 180
pF1KB3 YLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRT
::::.::::... .::: :: :. ::...
XP_006 MSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKA
10 20 30 40 50
190 200 210 220 230 240
pF1KB3 ENAQKAGHFDKEIVPVLVS------TRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGT
::. : :. ::::: .. :.:. : : :: : ....:...:::: : ::
XP_006 ARAQSKGCFQAEIVPVTTTVHDDKGTKRS-ITVTQDEGIRPSTTMEGLAKLKPAFKKDG-
60 70 80 90 100 110
250 260 270 280 290 300
pF1KB3 GTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQ
..: .:.: ..:::::..: ..:.:.. :: :. . :.. ::: :.:::::: ::
XP_006 -STTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV
120 130 140 150 160 170
310 320 330 340 350 360
pF1KB3 AVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRIL
:. ::: .. ::::::::::::. .: :..: : ::::: :::.::::::: .: : .
XP_006 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV
180 190 200 210 220 230
370 380 390
pF1KB3 VTLLHTLERMG-RSRGVAALCIGGGMGIAMCVQRE
.:::. :.: : :. ::...::: ::: :
XP_006 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN
240 250 260 270
397 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:25:02 2016 done: Thu Nov 3 13:25:03 2016
Total Scan time: 7.700 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]