Result of FASTA (ccds) for
pFN21AB3492
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3492, 397 aa
1>>>pF1KB3492 397 - 397 aa - 397 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4675+/-0.000952; mu= 15.7847+/- 0.057
mean_var=61.6654+/-12.344, 0's: 0 Z-trim(103.4): 29 B-trim: 0 in 0/50
Lambda= 0.163325
statistics sampled from 7373 (7388) to 7373 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.591), E-opt: 0.2 (0.227), width: 16
Scan time: 2.500
The best scores are: opt bits E(32554)
CCDS5268.1 ACAT2 gene_id:39|Hs108|chr6 ( 397) 2583 617.4 7e-177
CCDS8339.1 ACAT1 gene_id:38|Hs108|chr11 ( 427) 1030 251.5 1.1e-66
CCDS11939.1 ACAA2 gene_id:10449|Hs108|chr18 ( 397) 1001 244.7 1.1e-64
CCDS2673.1 ACAA1 gene_id:30|Hs108|chr3 ( 424) 841 207.0 2.7e-53
CCDS46794.1 ACAA1 gene_id:30|Hs108|chr3 ( 331) 350 91.3 1.5e-18
>>CCDS5268.1 ACAT2 gene_id:39|Hs108|chr6 (397 aa)
initn: 2583 init1: 2583 opt: 2583 Z-score: 3289.1 bits: 617.4 E(32554): 7e-177
Smith-Waterman score: 2583; 99.7% identity (100.0% similar) in 397 aa overlap (1-397:1-397)
10 20 30 40 50 60
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLT
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
CCDS52 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC
310 320 330 340 350 360
370 380 390
pF1KB3 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
:::::::::::::::::::::::::::::::::::::
CCDS52 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
370 380 390
>>CCDS8339.1 ACAT1 gene_id:38|Hs108|chr11 (427 aa)
initn: 993 init1: 395 opt: 1030 Z-score: 1310.9 bits: 251.5 E(32554): 1.1e-66
Smith-Waterman score: 1030; 43.8% identity (74.4% similar) in 390 aa overlap (8-396:42-426)
10 20 30
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTV
::::::.:: :::: :.:. .:. ::: .
CCDS83 ARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 IKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLK
:. ....: . :.:.:. .:.:: .: :: :.::: .:::.: :.: . . .:.::.:
CCDS83 IQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMK
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 AVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHN
:. .: ::. : ....::::::.::..:.. : .. : . : : :. :::::....
CCDS83 AIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKLEDLIVKDGLTDVYNK
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB3 CHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTR-RGLIEV
::: :::.::: ...:..:: :. : .:.. : .::.: .:..:: :... . . :
CCDS83 IHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVV
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB3 KTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTP
: :: .. .. . ::: : .. :::: :::: .::::::.::: . : . ..::
CCDS83 KEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAALVLMTADAAKRLNVTP
260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELG
:::::......::: . :.:. : .... .: . ::. ..:.::::. : : .: :
CCDS83 LARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 LNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQR
..:.::::.:::..::::.: :: ::. : :.: ..:. :.:..: ::: . :: .:.
CCDS83 IDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLASICNGGGGASAMLIQK
370 380 390 400 410 420
pF1KB3 E
CCDS83 L
>>CCDS11939.1 ACAA2 gene_id:10449|Hs108|chr18 (397 aa)
initn: 1023 init1: 534 opt: 1001 Z-score: 1274.5 bits: 244.7 E(32554): 1.1e-64
Smith-Waterman score: 1001; 42.7% identity (72.1% similar) in 391 aa overlap (8-395:7-394)
10 20 30 40 50 60
pF1KB3 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
: .:.: :: .:...: : . ::. . : .:. . :.:: :. ::.:.:
CCDS11 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNV
10 20 30 40 50
70 80 90 100 110
pF1KB3 LAAGCGQNPV-RQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGM
: .. . :.... .::: .:: . . .::::.... . : : . .. .:. ::
CCDS11 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 ENMSKAPHLAY-LRTGVKIG-EMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSRED
:.::.::. . .: :.:.: .. : ::. . ::: . :..::::.: : ..:::.
CCDS11 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 QDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRRGLIEVKTDEFPRHGSNIEAMSKLKPY
:: :. ::.: . :. ::.:. :..:. :.:..: ...:: : ...: ..:: :
CCDS11 CDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 FLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGP
: ::: :: .::::. :::.::.. ... . :...:::::::.. : .::::::::
CCDS11 FKKDGT--VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 IPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGA
.:::. :. ::: ::.:.:. :.::::: :. . : :. :.:..:::::::::::.
CCDS11 VPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGG
300 310 320 330 340 350
360 370 380 390
pF1KB3 SGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
:: :: . :.: :.: : . .:.. :::::.:::. .:
CCDS11 SGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
360 370 380 390
>>CCDS2673.1 ACAA1 gene_id:30|Hs108|chr3 (424 aa)
initn: 817 init1: 414 opt: 841 Z-score: 1070.3 bits: 207.0 E(32554): 2.7e-53
Smith-Waterman score: 841; 41.6% identity (66.4% similar) in 399 aa overlap (3-391:33-416)
10 20 30
pF1KB3 MNAGSDPVVIVSAARTIIGSFN-GALAAVPVQ
:.. ::.: . :: : . :.. . .
CCDS26 RLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 DLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMI
.: :.:. ::: ... ::..... :.:: : : .: :. . :: .:: . .
CCDS26 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 CGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGL
:.:::.:: . .: :. .: .: :.:.:: : . :. : : .
CCDS26 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR----------GNPGNITSRLME--
130 140 150 160 170
160 170 180 190 200
pF1KB3 TDAFHNC--HMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVS-
. ..: ::::.::::... .::: :: :. ::... ::. : :. ::::: ..
CCDS26 KEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTV
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB3 -----TRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVL
:.:. : : :: : ....:...:::: : :: ..: .:.: ..:::::..:
CCDS26 HDDKGTKRS-ITVTQDEGIRPSTTMEGLAKLKPAFKKDG--STTAGNSSQVSDGAAAILL
240 250 260 270 280
270 280 290 300 310 320
pF1KB3 MKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEA
..:.:.. :: :. . :.. ::: :.:::::: :: :. ::: .. ::::::::::
CCDS26 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB3 FAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAAL
::. .: :..: : ::::: :::.::::::: .: : ..:::. :.: : :. ::...
CCDS26 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
350 360 370 380 390 400
390
pF1KB3 CIGGGMGIAMCVQRE
::: ::: :
CCDS26 CIGTGMGAAAVFEYPGN
410 420
>>CCDS46794.1 ACAA1 gene_id:30|Hs108|chr3 (331 aa)
initn: 636 init1: 259 opt: 350 Z-score: 446.8 bits: 91.3 E(32554): 1.5e-18
Smith-Waterman score: 489; 33.5% identity (51.4% similar) in 397 aa overlap (3-391:33-323)
10 20 30
pF1KB3 MNAGSDPVVIVSAARTIIGSFN-GALAAVPVQ
:.. ::.: . :: : . :.. . .
CCDS46 RLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 DLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMI
.: :.:. ::: ... ::..... :.:: : : .: :. . :: .:: . .
CCDS46 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 CGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGL
:.:::.:: .:: :::..: :
CCDS46 CSSGLQAV-----------ASI--AGGIRN----------------------------GS
130 140
160 170 180 190 200
pF1KB3 TDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVS---
: : :::.::::... .::: :: :. ::... ::. : :. ::::: ..
CCDS46 YDIGMAC--GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHD
150 160 170 180 190
210 220 230 240 250 260
pF1KB3 ---TRRGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMK
:.:. : : :: : ....:...:::: : ::.
CCDS46 DKGTKRS-ITVTQDEGIRPSTTMEGLAKLKPAFKKDGS----------------------
200 210 220 230
270 280 290 300 310 320
pF1KB3 KSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFA
: :: .. ::::::::::::
CCDS46 ----------------------------------------TTAGLTVSDVDIFEINEAFA
240 250
330 340 350 360 370 380
pF1KB3 AVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAALCI
. .: :..: : ::::: :::.::::::: .: : ..:::. :.: : :. ::...::
CCDS46 SQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCI
260 270 280 290 300 310
390
pF1KB3 GGGMGIAMCVQRE
: ::: :
CCDS46 GTGMGAAAVFEYPGN
320 330
397 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:25:01 2016 done: Thu Nov 3 13:25:02 2016
Total Scan time: 2.500 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]