Result of FASTA (omim) for
pFN21AB3319
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3319, 806 aa
1>>>pF1KB3319 806 - 806 aa - 806 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6334+/-0.000419; mu= 18.9875+/- 0.026
mean_var=94.0052+/-18.337, 0's: 0 Z-trim(113.2): 301 B-trim: 2 in 1/53
Lambda= 0.132281
statistics sampled from 22074 (22431) to 22074 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.263), width: 16
Scan time: 10.730
The best scores are: opt bits E(85289)
XP_011537154 (OMIM: 604118) PREDICTED: rasGAP-acti ( 806) 5430 1047.5 0
XP_006719704 (OMIM: 604118) PREDICTED: rasGAP-acti ( 806) 5430 1047.5 0
XP_005254007 (OMIM: 604118) PREDICTED: rasGAP-acti ( 806) 5430 1047.5 0
NP_001180449 (OMIM: 604118) rasGAP-activating-like ( 806) 5430 1047.5 0
XP_006719705 (OMIM: 604118) PREDICTED: rasGAP-acti ( 805) 5412 1044.1 0
NP_001288131 (OMIM: 604118) rasGAP-activating-like ( 805) 5411 1043.9 0
XP_016875517 (OMIM: 604118) PREDICTED: rasGAP-acti ( 805) 5411 1043.9 0
NP_004649 (OMIM: 604118) rasGAP-activating-like pr ( 804) 5393 1040.5 0
XP_011537155 (OMIM: 604118) PREDICTED: rasGAP-acti ( 804) 5393 1040.5 0
XP_016875518 (OMIM: 604118) PREDICTED: rasGAP-acti ( 780) 4760 919.6 0
XP_016875519 (OMIM: 604118) PREDICTED: rasGAP-acti ( 780) 4760 919.6 0
XP_016875520 (OMIM: 604118) PREDICTED: rasGAP-acti ( 779) 4741 916.0 0
NP_001180450 (OMIM: 604118) rasGAP-activating-like ( 776) 4073 788.5 0
XP_011537156 (OMIM: 604118) PREDICTED: rasGAP-acti ( 447) 3010 585.5 1.8e-166
NP_008920 (OMIM: 607943) ras GTPase-activating pro ( 803) 2486 485.7 3.4e-136
XP_016867150 (OMIM: 607943) PREDICTED: ras GTPase- ( 840) 2449 478.6 4.8e-134
XP_011514025 (OMIM: 607943) PREDICTED: ras GTPase- ( 682) 1986 390.2 1.6e-107
NP_001073346 (OMIM: 607943) ras GTPase-activating ( 757) 1986 390.2 1.7e-107
XP_016867151 (OMIM: 607943) PREDICTED: ras GTPase- ( 794) 1986 390.3 1.8e-107
NP_006497 (OMIM: 601589) ras GTPase-activating pro ( 849) 682 141.4 1.6e-32
NP_001290175 (OMIM: 601589) ras GTPase-activating ( 853) 677 140.5 3e-32
XP_016862458 (OMIM: 601589) PREDICTED: ras GTPase- ( 871) 676 140.3 3.5e-32
NP_001290174 (OMIM: 601589) ras GTPase-activating ( 850) 672 139.5 5.9e-32
XP_011511361 (OMIM: 601589) PREDICTED: ras GTPase- ( 853) 666 138.4 1.3e-31
XP_016862457 (OMIM: 601589) PREDICTED: ras GTPase- ( 872) 666 138.4 1.3e-31
XP_016862461 (OMIM: 601589) PREDICTED: ras GTPase- ( 442) 537 113.5 2.1e-24
XP_016875927 (OMIM: 605182) PREDICTED: ras GTPase- ( 451) 450 96.9 2.1e-19
XP_016875928 (OMIM: 605182) PREDICTED: ras GTPase- ( 451) 450 96.9 2.1e-19
NP_001307750 (OMIM: 605182) ras GTPase-activating ( 451) 450 96.9 2.1e-19
XP_016862459 (OMIM: 601589) PREDICTED: ras GTPase- ( 707) 437 94.6 1.6e-18
NP_001307751 (OMIM: 605182) ras GTPase-activating ( 802) 422 91.8 1.3e-17
XP_011533143 (OMIM: 605182) PREDICTED: ras GTPase- ( 802) 422 91.8 1.3e-17
XP_011533144 (OMIM: 605182) PREDICTED: ras GTPase- ( 802) 422 91.8 1.3e-17
NP_031394 (OMIM: 605182) ras GTPase-activating pro ( 834) 422 91.8 1.3e-17
XP_016862460 (OMIM: 601589) PREDICTED: ras GTPase- ( 573) 334 74.9 1.1e-12
XP_006718799 (OMIM: 604146) PREDICTED: synaptotagm ( 293) 284 65.1 5.2e-10
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403) 284 65.2 6.6e-10
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409) 284 65.2 6.6e-10
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447) 284 65.2 7.1e-10
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449) 284 65.2 7.1e-10
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453) 284 65.2 7.2e-10
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478) 284 65.3 7.4e-10
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484) 284 65.3 7.5e-10
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528) 284 65.3 8e-10
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611) 284 65.3 8.9e-10
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617) 284 65.4 9e-10
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642) 284 65.4 9.3e-10
XP_011543639 (OMIM: 604146) PREDICTED: synaptotagm ( 648) 284 65.4 9.3e-10
XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651) 284 65.4 9.4e-10
XP_005274440 (OMIM: 604146) PREDICTED: synaptotagm ( 686) 284 65.4 9.8e-10
>>XP_011537154 (OMIM: 604118) PREDICTED: rasGAP-activati (806 aa)
initn: 5430 init1: 5430 opt: 5430 Z-score: 5602.4 bits: 1047.5 E(85289): 0
Smith-Waterman score: 5430; 99.9% identity (100.0% similar) in 806 aa overlap (1-806:1-806)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
730 740 750 760 770 780
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
XP_011 LADLDRAHEEFQQQERGKAALGPLGP
790 800
>>XP_006719704 (OMIM: 604118) PREDICTED: rasGAP-activati (806 aa)
initn: 5430 init1: 5430 opt: 5430 Z-score: 5602.4 bits: 1047.5 E(85289): 0
Smith-Waterman score: 5430; 99.9% identity (100.0% similar) in 806 aa overlap (1-806:1-806)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_006 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
730 740 750 760 770 780
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
XP_006 LADLDRAHEEFQQQERGKAALGPLGP
790 800
>>XP_005254007 (OMIM: 604118) PREDICTED: rasGAP-activati (806 aa)
initn: 5430 init1: 5430 opt: 5430 Z-score: 5602.4 bits: 1047.5 E(85289): 0
Smith-Waterman score: 5430; 99.9% identity (100.0% similar) in 806 aa overlap (1-806:1-806)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_005 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
730 740 750 760 770 780
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
XP_005 LADLDRAHEEFQQQERGKAALGPLGP
790 800
>>NP_001180449 (OMIM: 604118) rasGAP-activating-like pro (806 aa)
initn: 5430 init1: 5430 opt: 5430 Z-score: 5602.4 bits: 1047.5 E(85289): 0
Smith-Waterman score: 5430; 99.9% identity (100.0% similar) in 806 aa overlap (1-806:1-806)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_001 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
730 740 750 760 770 780
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
NP_001 LADLDRAHEEFQQQERGKAALGPLGP
790 800
>>XP_006719705 (OMIM: 604118) PREDICTED: rasGAP-activati (805 aa)
initn: 3721 init1: 3721 opt: 5412 Z-score: 5583.9 bits: 1044.1 E(85289): 0
Smith-Waterman score: 5412; 99.8% identity (99.9% similar) in 806 aa overlap (1-806:1-805)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_006 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DFLDRLVDVDGDE-AGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
550 560 570 580 590
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
720 730 740 750 760 770
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
XP_006 LADLDRAHEEFQQQERGKAALGPLGP
780 790 800
>>NP_001288131 (OMIM: 604118) rasGAP-activating-like pro (805 aa)
initn: 3086 init1: 3086 opt: 5411 Z-score: 5582.8 bits: 1043.9 E(85289): 0
Smith-Waterman score: 5411; 99.8% identity (99.9% similar) in 806 aa overlap (1-806:1-805)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_001 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_001 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQ-DVKYLAISGFLFLRFFAPAIL
430 440 450 460 470
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
720 730 740 750 760 770
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
NP_001 LADLDRAHEEFQQQERGKAALGPLGP
780 790 800
>>XP_016875517 (OMIM: 604118) PREDICTED: rasGAP-activati (805 aa)
initn: 3086 init1: 3086 opt: 5411 Z-score: 5582.8 bits: 1043.9 E(85289): 0
Smith-Waterman score: 5411; 99.8% identity (99.9% similar) in 806 aa overlap (1-806:1-805)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_016 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQ-DVKYLAISGFLFLRFFAPAIL
430 440 450 460 470
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
720 730 740 750 760 770
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
XP_016 LADLDRAHEEFQQQERGKAALGPLGP
780 790 800
>>NP_004649 (OMIM: 604118) rasGAP-activating-like protei (804 aa)
initn: 4783 init1: 3086 opt: 5393 Z-score: 5564.3 bits: 1040.5 E(85289): 0
Smith-Waterman score: 5393; 99.6% identity (99.8% similar) in 806 aa overlap (1-806:1-804)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_004 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_004 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQ-DVKYLAISGFLFLRFFAPAIL
430 440 450 460 470
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DFLDRLVDVDGDE-AGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
720 730 740 750 760 770
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
NP_004 LADLDRAHEEFQQQERGKAALGPLGP
780 790 800
>>XP_011537155 (OMIM: 604118) PREDICTED: rasGAP-activati (804 aa)
initn: 4783 init1: 3086 opt: 5393 Z-score: 5564.3 bits: 1040.5 E(85289): 0
Smith-Waterman score: 5393; 99.6% identity (99.8% similar) in 806 aa overlap (1-806:1-804)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQ-DVKYLAISGFLFLRFFAPAIL
430 440 450 460 470
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFLDRLVDVDGDE-AGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
720 730 740 750 760 770
790 800
pF1KB3 LADLDRAHEEFQQQERGKAALGPLGP
::::::::::::::::::::::::::
XP_011 LADLDRAHEEFQQQERGKAALGPLGP
780 790 800
>>XP_016875518 (OMIM: 604118) PREDICTED: rasGAP-activati (780 aa)
initn: 4760 init1: 4760 opt: 4760 Z-score: 4911.6 bits: 919.6 E(85289): 0
Smith-Waterman score: 4760; 99.7% identity (100.0% similar) in 705 aa overlap (1-705:1-705)
10 20 30 40 50 60
pF1KB3 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAKSSSLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLDFHQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVQMLEDGQGRCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVLELREMPGAPSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQKPPKGWFRLLPFPRAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDSGGNLGALRVKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CRQDLATKLVKLFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 CRQDLATKLVKLFLGRGLAGRFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYLHEVLKPVISRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIVDAIVGSVGRCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKLFDLRDQHADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFLDRLVDVDGDEEAGVPARALFPPSAIVREGYLLKRKEEPAGLATRFAFKKRYVWLSGE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSFSKSPEWQMCHSIPVSHIRAVERVDEGAFQLPHVMQVVTQDGTGALHTTYLQCKNVN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSAAGCSRTHSAVTLGDWSD
:::::::::::::::::::::::::::::::::::::::::::.:
XP_016 ELNQWLSALRKASAPNPNKLAACHPGAFRSARWTCCLQAERSASGWGLKEGFLEEVLLKC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 PLDPDAEAQTVYRQLLLGRDQLRLKLLEDSNMDTTLEADTGACPEVLARQRAATARLLEV
XP_016 DLSRAEVKQRHWRQNWEMGPPAAAVHTQLSPWGTGVTHWILMLRPRQCIGSCSWGGTSSG
730 740 750 760 770 780
806 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:50:34 2016 done: Thu Nov 3 12:50:36 2016
Total Scan time: 10.730 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]