Result of FASTA (omim) for
pFN21AB3248
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3248, 210 aa
1>>>pF1KB3248 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0037+/-0.000345; mu= 15.4032+/- 0.021
mean_var=65.5246+/-12.895, 0's: 0 Z-trim(114.9): 67 B-trim: 0 in 0/51
Lambda= 0.158443
statistics sampled from 24868 (24940) to 24868 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.292), width: 16
Scan time: 6.000
The best scores are: opt bits E(85289)
NP_001010934 (OMIM: 142409,608265) hepatocyte grow ( 210) 1475 345.6 3.6e-95
XP_016867586 (OMIM: 142409,608265) PREDICTED: hepa ( 290) 1461 342.5 4.2e-94
NP_001010931 (OMIM: 142409,608265) hepatocyte grow ( 290) 1461 342.5 4.2e-94
XP_006716019 (OMIM: 142409,608265) PREDICTED: hepa ( 728) 1461 342.7 8.8e-94
NP_000592 (OMIM: 142409,608265) hepatocyte growth ( 728) 1461 342.7 8.8e-94
NP_001010933 (OMIM: 142409,608265) hepatocyte grow ( 285) 1408 330.3 1.8e-90
XP_016867587 (OMIM: 142409,608265) PREDICTED: hepa ( 285) 1408 330.3 1.8e-90
NP_001010932 (OMIM: 142409,608265) hepatocyte grow ( 723) 1408 330.6 3.9e-90
XP_011514417 (OMIM: 142409,608265) PREDICTED: hepa ( 723) 1408 330.6 3.9e-90
XP_016861957 (OMIM: 142408) PREDICTED: hepatocyte ( 366) 466 115.1 1.5e-25
XP_016861954 (OMIM: 142408) PREDICTED: hepatocyte ( 645) 466 115.3 2.3e-25
XP_016861953 (OMIM: 142408) PREDICTED: hepatocyte ( 648) 466 115.3 2.3e-25
XP_016861952 (OMIM: 142408) PREDICTED: hepatocyte ( 667) 466 115.3 2.4e-25
XP_016861956 (OMIM: 142408) PREDICTED: hepatocyte ( 535) 452 112.0 1.8e-24
XP_016861955 (OMIM: 142408) PREDICTED: hepatocyte ( 552) 452 112.0 1.9e-24
XP_016861951 (OMIM: 142408) PREDICTED: hepatocyte ( 702) 452 112.1 2.3e-24
XP_016861950 (OMIM: 142408) PREDICTED: hepatocyte ( 706) 452 112.1 2.3e-24
XP_016861949 (OMIM: 142408) PREDICTED: hepatocyte ( 718) 452 112.1 2.3e-24
XP_011532034 (OMIM: 142408) PREDICTED: hepatocyte ( 737) 452 112.1 2.4e-24
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810) 450 111.7 3.5e-24
NP_005568 (OMIM: 152200) apolipoprotein(a) precurs (2040) 335 85.7 6e-16
NP_001298186 (OMIM: 176930,188050,601367,613679,61 ( 606) 325 83.0 1.1e-15
NP_000497 (OMIM: 176930,188050,601367,613679,61439 ( 622) 325 83.0 1.1e-15
XP_016870252 (OMIM: 113000,268310,602337) PREDICTE ( 803) 310 79.7 1.5e-14
XP_005252065 (OMIM: 113000,268310,602337) PREDICTE ( 803) 310 79.7 1.5e-14
XP_006717184 (OMIM: 113000,268310,602337) PREDICTE ( 803) 310 79.7 1.5e-14
XP_016870251 (OMIM: 113000,268310,602337) PREDICTE ( 940) 310 79.7 1.7e-14
NP_004551 (OMIM: 113000,268310,602337) tyrosine-pr ( 943) 310 79.7 1.7e-14
XP_011532040 (OMIM: 142408) PREDICTED: hepatocyte ( 515) 303 77.9 3.2e-14
XP_011532039 (OMIM: 142408) PREDICTED: hepatocyte ( 523) 303 77.9 3.2e-14
NP_066278 (OMIM: 142408) hepatocyte growth factor- ( 725) 303 78.0 4.2e-14
XP_006713229 (OMIM: 142408) PREDICTED: hepatocyte ( 680) 302 77.8 4.7e-14
NP_001077061 (OMIM: 602336) inactive tyrosine-prot ( 393) 294 75.8 1.1e-13
XP_011539828 (OMIM: 602336) PREDICTED: inactive ty ( 874) 293 75.8 2.4e-13
XP_016856866 (OMIM: 602336) PREDICTED: inactive ty ( 874) 293 75.8 2.4e-13
XP_016856865 (OMIM: 602336) PREDICTED: inactive ty ( 917) 293 75.8 2.5e-13
NP_005003 (OMIM: 602336) inactive tyrosine-protein ( 937) 293 75.8 2.5e-13
NP_001161810 (OMIM: 173350,217090) plasminogen iso ( 136) 244 64.0 1.3e-10
NP_001305133 (OMIM: 113000,268310,602337) tyrosine ( 432) 243 64.2 3.8e-10
NP_001306118 (OMIM: 173370,612348) tissue-type pla ( 473) 241 63.7 5.5e-10
NP_127509 (OMIM: 173370,612348) tissue-type plasmi ( 516) 241 63.8 5.9e-10
NP_000921 (OMIM: 173370,612348) tissue-type plasmi ( 562) 241 63.8 6.3e-10
XP_011532764 (OMIM: 234000,610618,610619) PREDICTE ( 503) 195 53.2 8.5e-07
NP_001171131 (OMIM: 188050,603924,616535) hyaluron ( 534) 195 53.3 8.9e-07
NP_004123 (OMIM: 188050,603924,616535) hyaluronan- ( 560) 195 53.3 9.3e-07
NP_000496 (OMIM: 234000,610618,610619) coagulation ( 615) 195 53.3 1e-06
XP_016884478 (OMIM: 609898) PREDICTED: kremen prot ( 365) 181 49.9 6.1e-06
XP_011528732 (OMIM: 609898) PREDICTED: kremen prot ( 382) 181 50.0 6.3e-06
NP_001034659 (OMIM: 609898) kremen protein 1 isofo ( 458) 181 50.0 7.3e-06
XP_011528731 (OMIM: 609898) PREDICTED: kremen prot ( 475) 181 50.0 7.5e-06
>>NP_001010934 (OMIM: 142409,608265) hepatocyte growth f (210 aa)
initn: 1475 init1: 1475 opt: 1475 Z-score: 1829.7 bits: 345.6 E(85289): 3.6e-95
Smith-Waterman score: 1475; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
130 140 150 160 170 180
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::::
NP_001 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
190 200 210
>>XP_016867586 (OMIM: 142409,608265) PREDICTED: hepatocy (290 aa)
initn: 1461 init1: 1461 opt: 1461 Z-score: 1810.4 bits: 342.5 E(85289): 4.2e-94
Smith-Waterman score: 1461; 100.0% identity (100.0% similar) in 208 aa overlap (1-208:1-208)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
130 140 150 160 170 180
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::
XP_016 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
190 200 210 220 230 240
>--
initn: 287 init1: 186 opt: 286 Z-score: 358.8 bits: 73.9 E(85289): 3e-13
Smith-Waterman score: 286; 45.6% identity (70.9% similar) in 79 aa overlap (128-206:211-288)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:.::.: .. :.:: :: :. . :
XP_016 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
190 200 210 220 230 240
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.:.::: : : ...:::::: :. :::.: .:..:.: : : :
XP_016 HRHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCET
250 260 270 280 290
>>NP_001010931 (OMIM: 142409,608265) hepatocyte growth f (290 aa)
initn: 1461 init1: 1461 opt: 1461 Z-score: 1810.4 bits: 342.5 E(85289): 4.2e-94
Smith-Waterman score: 1461; 100.0% identity (100.0% similar) in 208 aa overlap (1-208:1-208)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
130 140 150 160 170 180
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::
NP_001 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
190 200 210 220 230 240
>--
initn: 287 init1: 186 opt: 286 Z-score: 358.8 bits: 73.9 E(85289): 3e-13
Smith-Waterman score: 286; 45.6% identity (70.9% similar) in 79 aa overlap (128-206:211-288)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:.::.: .. :.:: :: :. . :
NP_001 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
190 200 210 220 230 240
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.:.::: : : ...:::::: :. :::.: .:..:.: : : :
NP_001 HRHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCET
250 260 270 280 290
>>XP_006716019 (OMIM: 142409,608265) PREDICTED: hepatocy (728 aa)
initn: 1461 init1: 1461 opt: 1461 Z-score: 1804.7 bits: 342.7 E(85289): 8.8e-94
Smith-Waterman score: 1461; 100.0% identity (100.0% similar) in 208 aa overlap (1-208:1-208)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
130 140 150 160 170 180
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::
XP_006 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
190 200 210 220 230 240
>--
initn: 491 init1: 245 opt: 334 Z-score: 412.4 bits: 85.1 E(85289): 3.1e-16
Smith-Waterman score: 334; 51.2% identity (77.9% similar) in 86 aa overlap (128-210:305-389)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:: :.:..:.:::. .:: :: :.:. :
XP_006 DPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYP
280 290 300 310 320 330
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCD-IPQC--SEGK
:::.. : ... :::.::::::: : :. :::::..:..: :. ::.: :.:.
XP_006 HEHDMTPENFKCKDLRENYCRNPDGSES-PWCFTTDPNIRVGYCSQIPNCDMSHGQDCYR
340 350 360 370 380 390
XP_006 GNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCY
400 410 420 430 440 450
>--
initn: 290 init1: 186 opt: 289 Z-score: 356.8 bits: 74.8 E(85289): 3.9e-13
Smith-Waterman score: 289; 44.4% identity (71.6% similar) in 81 aa overlap (128-208:211-290)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:.::.: .. :.:: :: :. . :
XP_006 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
190 200 210 220 230 240
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.:.::: : : ...:::::: :. :::.: .:..:.: : : :..
XP_006 HRHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCADNTMNDTDVP
250 260 270 280 290
XP_006 LETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDG
300 310 320 330 340 350
>--
initn: 179 init1: 157 opt: 250 Z-score: 308.7 bits: 65.9 E(85289): 1.9e-10
Smith-Waterman score: 250; 40.7% identity (68.6% similar) in 86 aa overlap (127-209:390-471)
100 110 120 130 140 150
pF1KB3 LWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMI
.: :.:..: :..: :.::. :. :.. .
XP_006 SESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNM
360 370 380 390 400 410
160 170 180 190 200 210
pF1KB3 P--HEHSFL-PSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.: : :.. . :.::::::: . ::::.:.:: . .. : : .: ::
XP_006 EDLHRHIFWEPDASK---LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC-EGDTTP
420 430 440 450 460 470
XP_006 TIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQC
480 490 500 510 520 530
>>NP_000592 (OMIM: 142409,608265) hepatocyte growth fact (728 aa)
initn: 1461 init1: 1461 opt: 1461 Z-score: 1804.7 bits: 342.7 E(85289): 8.8e-94
Smith-Waterman score: 1461; 100.0% identity (100.0% similar) in 208 aa overlap (1-208:1-208)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
130 140 150 160 170 180
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::
NP_000 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
190 200 210 220 230 240
>--
initn: 491 init1: 245 opt: 334 Z-score: 412.4 bits: 85.1 E(85289): 3.1e-16
Smith-Waterman score: 334; 51.2% identity (77.9% similar) in 86 aa overlap (128-210:305-389)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:: :.:..:.:::. .:: :: :.:. :
NP_000 DPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYP
280 290 300 310 320 330
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCD-IPQC--SEGK
:::.. : ... :::.::::::: : :. :::::..:..: :. ::.: :.:.
NP_000 HEHDMTPENFKCKDLRENYCRNPDGSES-PWCFTTDPNIRVGYCSQIPNCDMSHGQDCYR
340 350 360 370 380 390
NP_000 GNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCY
400 410 420 430 440 450
>--
initn: 290 init1: 186 opt: 289 Z-score: 356.8 bits: 74.8 E(85289): 3.9e-13
Smith-Waterman score: 289; 44.4% identity (71.6% similar) in 81 aa overlap (128-208:211-290)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:.::.: .. :.:: :: :. . :
NP_000 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
190 200 210 220 230 240
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.:.::: : : ...:::::: :. :::.: .:..:.: : : :..
NP_000 HRHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCADNTMNDTDVP
250 260 270 280 290
NP_000 LETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDG
300 310 320 330 340 350
>--
initn: 179 init1: 157 opt: 250 Z-score: 308.7 bits: 65.9 E(85289): 1.9e-10
Smith-Waterman score: 250; 40.7% identity (68.6% similar) in 86 aa overlap (127-209:390-471)
100 110 120 130 140 150
pF1KB3 LWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMI
.: :.:..: :..: :.::. :. :.. .
NP_000 SESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNM
360 370 380 390 400 410
160 170 180 190 200 210
pF1KB3 P--HEHSFL-PSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.: : :.. . :.::::::: . ::::.:.:: . .. : : .: ::
NP_000 EDLHRHIFWEPDASK---LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC-EGDTTP
420 430 440 450 460 470
NP_000 TIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQC
480 490 500 510 520 530
>>NP_001010933 (OMIM: 142409,608265) hepatocyte growth f (285 aa)
initn: 1360 init1: 1105 opt: 1408 Z-score: 1745.0 bits: 330.3 E(85289): 1.8e-90
Smith-Waterman score: 1408; 97.6% identity (97.6% similar) in 208 aa overlap (1-208:1-203)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNP
130 140 150 160 170
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::
NP_001 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
180 190 200 210 220 230
>--
initn: 287 init1: 186 opt: 286 Z-score: 358.9 bits: 73.9 E(85289): 3e-13
Smith-Waterman score: 286; 45.6% identity (70.9% similar) in 79 aa overlap (128-206:206-283)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:.::.: .. :.:: :: :. . :
NP_001 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.:.::: : : ...:::::: :. :::.: .:..:.: : : :
NP_001 HRHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCET
240 250 260 270 280
>>XP_016867587 (OMIM: 142409,608265) PREDICTED: hepatocy (285 aa)
initn: 1360 init1: 1105 opt: 1408 Z-score: 1745.0 bits: 330.3 E(85289): 1.8e-90
Smith-Waterman score: 1408; 97.6% identity (97.6% similar) in 208 aa overlap (1-208:1-203)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_016 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNP
130 140 150 160 170
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::
XP_016 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
180 190 200 210 220 230
>--
initn: 287 init1: 186 opt: 286 Z-score: 358.9 bits: 73.9 E(85289): 3e-13
Smith-Waterman score: 286; 45.6% identity (70.9% similar) in 79 aa overlap (128-206:206-283)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:.::.: .. :.:: :: :. . :
XP_016 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.:.::: : : ...:::::: :. :::.: .:..:.: : : :
XP_016 HRHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCET
240 250 260 270 280
>>NP_001010932 (OMIM: 142409,608265) hepatocyte growth f (723 aa)
initn: 1568 init1: 1105 opt: 1408 Z-score: 1739.3 bits: 330.6 E(85289): 3.9e-90
Smith-Waterman score: 1408; 97.6% identity (97.6% similar) in 208 aa overlap (1-208:1-203)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNP
130 140 150 160 170
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::
NP_001 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
180 190 200 210 220 230
>--
initn: 491 init1: 245 opt: 334 Z-score: 412.5 bits: 85.1 E(85289): 3.1e-16
Smith-Waterman score: 334; 51.2% identity (77.9% similar) in 86 aa overlap (128-210:300-384)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:: :.:..:.:::. .:: :: :.:. :
NP_001 DPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYP
270 280 290 300 310 320
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCD-IPQC--SEGK
:::.. : ... :::.::::::: : :. :::::..:..: :. ::.: :.:.
NP_001 HEHDMTPENFKCKDLRENYCRNPDGSES-PWCFTTDPNIRVGYCSQIPNCDMSHGQDCYR
330 340 350 360 370 380
NP_001 GNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCY
390 400 410 420 430 440
>--
initn: 290 init1: 186 opt: 289 Z-score: 356.9 bits: 74.8 E(85289): 3.9e-13
Smith-Waterman score: 289; 44.4% identity (71.6% similar) in 81 aa overlap (128-208:206-285)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:.::.: .. :.:: :: :. . :
NP_001 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.:.::: : : ...:::::: :. :::.: .:..:.: : : :..
NP_001 HRHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCADNTMNDTDVP
240 250 260 270 280 290
NP_001 LETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDG
300 310 320 330 340 350
>--
initn: 179 init1: 157 opt: 250 Z-score: 308.7 bits: 65.9 E(85289): 1.9e-10
Smith-Waterman score: 250; 40.7% identity (68.6% similar) in 86 aa overlap (127-209:385-466)
100 110 120 130 140 150
pF1KB3 LWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMI
.: :.:..: :..: :.::. :. :.. .
NP_001 SESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNM
360 370 380 390 400 410
160 170 180 190 200 210
pF1KB3 P--HEHSFL-PSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.: : :.. . :.::::::: . ::::.:.:: . .. : : .: ::
NP_001 EDLHRHIFWEPDASK---LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC-EGDTTP
420 430 440 450 460 470
NP_001 TIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQC
480 490 500 510 520 530
>>XP_011514417 (OMIM: 142409,608265) PREDICTED: hepatocy (723 aa)
initn: 1568 init1: 1105 opt: 1408 Z-score: 1739.3 bits: 330.6 E(85289): 3.9e-90
Smith-Waterman score: 1408; 97.6% identity (97.6% similar) in 208 aa overlap (1-208:1-203)
10 20 30 40 50 60
pF1KB3 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_011 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNP
130 140 150 160 170
190 200 210
pF1KB3 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::::::::::::::::::::::::::::
XP_011 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
180 190 200 210 220 230
>--
initn: 491 init1: 245 opt: 334 Z-score: 412.5 bits: 85.1 E(85289): 3.1e-16
Smith-Waterman score: 334; 51.2% identity (77.9% similar) in 86 aa overlap (128-210:300-384)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:: :.:..:.:::. .:: :: :.:. :
XP_011 DPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYP
270 280 290 300 310 320
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCD-IPQC--SEGK
:::.. : ... :::.::::::: : :. :::::..:..: :. ::.: :.:.
XP_011 HEHDMTPENFKCKDLRENYCRNPDGSES-PWCFTTDPNIRVGYCSQIPNCDMSHGQDCYR
330 340 350 360 370 380
XP_011 GNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCY
390 400 410 420 430 440
>--
initn: 290 init1: 186 opt: 289 Z-score: 356.9 bits: 74.8 E(85289): 3.9e-13
Smith-Waterman score: 289; 44.4% identity (71.6% similar) in 81 aa overlap (128-208:206-285)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:.::.: .. :.:: :: :. . :
XP_011 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.:.::: : : ...:::::: :. :::.: .:..:.: : : :..
XP_011 HRHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCADNTMNDTDVP
240 250 260 270 280 290
XP_011 LETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDG
300 310 320 330 340 350
>--
initn: 179 init1: 157 opt: 250 Z-score: 308.7 bits: 65.9 E(85289): 1.9e-10
Smith-Waterman score: 250; 40.7% identity (68.6% similar) in 86 aa overlap (127-209:385-466)
100 110 120 130 140 150
pF1KB3 LWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMI
.: :.:..: :..: :.::. :. :.. .
XP_011 SESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNM
360 370 380 390 400 410
160 170 180 190 200 210
pF1KB3 P--HEHSFL-PSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
:.: : :.. . :.::::::: . ::::.:.:: . .. : : .: ::
XP_011 EDLHRHIFWEPDASK---LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC-EGDTTP
420 430 440 450 460 470
XP_011 TIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQC
480 490 500 510 520 530
>>XP_016861957 (OMIM: 142408) PREDICTED: hepatocyte grow (366 aa)
initn: 562 init1: 187 opt: 466 Z-score: 579.8 bits: 115.1 E(85289): 1.5e-25
Smith-Waterman score: 466; 34.4% identity (64.6% similar) in 209 aa overlap (2-208:5-202)
10 20 30 40 50
pF1KB3 MWVTKLLPALLLQHVLLHLLLLP-IAIPYAEGQRKRRNTIHEFKKSAKTTLIK-IDP
::: :: . . : ::: ...: :::. : .. .. . :.. . :
XP_016 MGLWWVTVQPPARRMGWLPLLLLLTQCLGVP---GQRSPLNDFQVLRGTELQHLLHAVVP
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 ALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHE
. . : :..::.:: : . :.:: .. . . : .:... : .. . . .
XP_016 G--PWQEDVADAEECAGRC----GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 FDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQEN
::...:::.:.::...: .:.::.. : .:. :: :: .:..:.. :. : :.::
XP_016 CDLFQKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNG--LEEN
120 130 140 150 160
180 190 200 210
pF1KB3 YCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
.:::: :. :::::.:..: ::.. : : .: :
XP_016 FCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRW
170 180 190 200 210 220
XP_016 DLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPR
230 240 250 260 270 280
>--
initn: 289 init1: 185 opt: 300 Z-score: 374.7 bits: 77.1 E(85289): 3.9e-14
Smith-Waterman score: 300; 44.0% identity (76.2% similar) in 84 aa overlap (128-210:205-287)
100 110 120 130 140 150
pF1KB3 WFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP
:. .:. :.:.:. :.:: .:: :. . :
XP_016 DGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHP
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB3 HEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQC-SEGK
:.: : :... . :..:::::: : : :::.:..:... : ::.:.: ::..
XP_016 HQHPFEPGKFLDQGLDDNYCRNPDGSER-PWCYTTDPQIEREFCDLPRCGSEAQPRQEAT
240 250 260 270 280 290
XP_016 TVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKLLPRRRGAVPRHGQ
300 310 320 330 340 350
>--
initn: 177 init1: 177 opt: 179 Z-score: 225.2 bits: 49.5 E(85289): 8.3e-06
Smith-Waterman score: 179; 39.1% identity (65.6% similar) in 64 aa overlap (127-189:296-359)
100 110 120 130 140 150
pF1KB3 LWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMI
.:. :::..:.::.. : .:. :: :...:
XP_016 YTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQI
270 280 290 300 310 320
160 170 180 190 200 210
pF1KB3 PHEHSFLPSSYRGKDLQENYCRNPR-GEEGGPWCFTSNPEVRYEVCDIPQCSEGK
::.: : : .: : : . :: :.. :
XP_016 PHQHRFTPEKYACKLLPRRRGAVPRHGQQDPQGCPVPALVR
330 340 350 360
210 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:39:13 2016 done: Thu Nov 3 12:39:14 2016
Total Scan time: 6.000 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]