Result of FASTA (omim) for
pFN21AB3098
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3098, 646 aa
1>>>pF1KB3098 646 - 646 aa - 646 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6980+/-0.000421; mu= -1.7232+/- 0.026
mean_var=544.4985+/-120.461, 0's: 0 Z-trim(123.3): 49 B-trim: 33 in 1/57
Lambda= 0.054964
statistics sampled from 42812 (42892) to 42812 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.503), width: 16
Scan time: 13.540
The best scores are: opt bits E(85289)
NP_003381 (OMIM: 193525) wee1-like protein kinase ( 646) 4352 360.2 1.3e-98
NP_001137448 (OMIM: 193525) wee1-like protein kina ( 432) 2830 239.3 2.2e-62
NP_001099028 (OMIM: 614084) wee1-like protein kina ( 567) 1400 126.1 3.5e-28
>>NP_003381 (OMIM: 193525) wee1-like protein kinase isof (646 aa)
initn: 4352 init1: 4352 opt: 4352 Z-score: 1891.5 bits: 360.2 E(85289): 1.3e-98
Smith-Waterman score: 4352; 100.0% identity (100.0% similar) in 646 aa overlap (1-646:1-646)
10 20 30 40 50 60
pF1KB3 MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 RYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 RFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 EFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKK
550 560 570 580 590 600
610 620 630 640
pF1KB3 AQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
610 620 630 640
>>NP_001137448 (OMIM: 193525) wee1-like protein kinase i (432 aa)
initn: 2830 init1: 2830 opt: 2830 Z-score: 1241.1 bits: 239.3 E(85289): 2.2e-62
Smith-Waterman score: 2830; 100.0% identity (100.0% similar) in 432 aa overlap (215-646:1-432)
190 200 210 220 230 240
pF1KB3 FDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLL
::::::::::::::::::::::::::::::
NP_001 MDTEKSGKREFDVRQTPQVNINPFTPDSLL
10 20 30
250 260 270 280 290 300
pF1KB3 LHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEK
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB3 IGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFS
100 110 120 130 140 150
370 380 390 400 410 420
pF1KB3 AWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVH
160 170 180 190 200 210
430 440 450 460 470 480
pF1KB3 MDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLA
220 230 240 250 260 270
490 500 510 520 530 540
pF1KB3 NEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTE
280 290 300 310 320 330
550 560 570 580 590 600
pF1KB3 LLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMA
340 350 360 370 380 390
610 620 630 640
pF1KB3 KAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
400 410 420 430
>>NP_001099028 (OMIM: 614084) wee1-like protein kinase 2 (567 aa)
initn: 1467 init1: 721 opt: 1400 Z-score: 627.0 bits: 126.1 E(85289): 3.5e-28
Smith-Waterman score: 1474; 51.7% identity (72.9% similar) in 484 aa overlap (168-644:92-559)
140 150 160 170 180 190
pF1KB3 FSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSK
:. :. : .. :: :.: :::..::.
NP_001 NVHELDTSSEKDKESPDQILRTPVSHPLKCPETPAQPDSRS--KLLPSDSPSTPKTMLSR
70 80 90 100 110
200 210 220 230 240 250
pF1KB3 ARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDS---LLLHSSGQCRRR
.... :: . . : : : . . ::::::::.: :.:.:.: .:.
NP_001 LVISPTGKLPSRGPKHLKLTPAPLKDE--MTSLALVNINPFTPESYKKLFLQSGG--KRK
120 130 140 150 160 170
260 270 280 290 300 310
pF1KB3 KRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVF
: : :.: . : :::: .. :.:: ::: :: :.:::: ::::.:.
NP_001 IR-------G-DLEEAGPEEGKGGLPAKRCVLRETNMASRYEKEFLEVEKIGVGEFGTVY
180 190 200 210 220
320 330 340 350 360 370
pF1KB3 KCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLI
::.::::::.:::::: : .. .:..::.:::::::::.: :::::.:.:::::::.:
NP_001 KCIKRLDGCVYAIKRSMKTFTELSNENSALHEVYAHAVLGHHPHVVRYYSSWAEDDHMII
230 240 250 260 270 280
380 390 400 410 420 430
pF1KB3 QNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFI
:::::::::: ::::: . ..:.: .:::.:::.. :: :::. :.::.:::::::::
NP_001 QNEYCNGGSLQAAISENTKSGNHFEEPKLKDILLQISLGLNYIHNSSMVHLDIKPSNIFI
290 300 310 320 330 340
440 450 460 470 480 490
pF1KB3 SRT--SIPNAASEE-GDEDDW-ASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQE
. : ... :: .: :: : .::.:::::::.: :..:.::::::::::::.:::
NP_001 CHKMQSESSGVIEEVENEADWFLSANVMYKIGDLGHATSINKPKVEEGDSRFLANEILQE
350 360 370 380 390 400
500 510 520 530 540 550
pF1KB3 NYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMI
.: ::::::::::.::.. ::::: :: :: ::.::.: .: .:: ::. :. ::: ::
NP_001 DYRHLPKADIFALGLTIAVAAGAESLPTNGAAWHHIRKGNFPDVPQELSESFSSLLKNMI
410 420 430 440 450 460
560 570 580 590 600 610
pF1KB3 HPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEE
.:: :.:::: ::....:: . :. :.:. .:: ::::.. :..::..::.:.. .
NP_001 QPDAEQRPSAAALARNTVLRPSLGKT-EELQQQLNLEKFKTATLERELREAQQAQSP-QG
470 480 490 500 510 520
620 630 640
pF1KB3 RALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
. : .. . : : :.::.: : :: :.:
NP_001 YTHHGDTGVSGTHTGSRSTKRLVGGKSARSSSFTSGEREPLH
530 540 550 560
646 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:22:27 2016 done: Thu Nov 3 12:22:28 2016
Total Scan time: 13.540 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]