Result of FASTA (omim) for
pFN21ASDB0046
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDB0046, 1975 aa
1>>>pF1KSDB0046 1975 - 1975 aa - 1975 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6917+/-0.000455; mu= -0.3111+/- 0.028
mean_var=266.3591+/-54.162, 0's: 0 Z-trim(118.2): 7 B-trim: 512 in 1/55
Lambda= 0.078585
statistics sampled from 30905 (30912) to 30905 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.362), width: 16
Scan time: 19.700
The best scores are: opt bits E(85289)
NP_001135451 (OMIM: 605230) tumor suppressor p53-b (1975) 13040 1493.4 0
NP_001135452 (OMIM: 605230) tumor suppressor p53-b (1977) 13026 1491.8 0
NP_005648 (OMIM: 605230) tumor suppressor p53-bind (1972) 12988 1487.5 0
XP_011520288 (OMIM: 605230) PREDICTED: tumor suppr (1700) 11127 1276.5 0
XP_011520287 (OMIM: 605230) PREDICTED: tumor suppr (1927) 8964 1031.3 0
XP_016878022 (OMIM: 605230) PREDICTED: tumor suppr (1017) 6742 779.2 0
>>NP_001135451 (OMIM: 605230) tumor suppressor p53-bindi (1975 aa)
initn: 13040 init1: 13040 opt: 13040 Z-score: 7998.3 bits: 1493.4 E(85289): 0
Smith-Waterman score: 13040; 100.0% identity (100.0% similar) in 1975 aa overlap (1-1975:1-1975)
10 20 30 40 50 60
pF1KSD MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD ERSPAKRGRKSATVKPVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERSPAKRGRKSATVKPVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLT
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KSD MATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCN
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KSD TAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KSD RILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVF
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970
pF1KSD DVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
1930 1940 1950 1960 1970
>>NP_001135452 (OMIM: 605230) tumor suppressor p53-bindi (1977 aa)
initn: 11131 init1: 11131 opt: 13026 Z-score: 7989.8 bits: 1491.8 E(85289): 0
Smith-Waterman score: 13026; 99.9% identity (99.9% similar) in 1977 aa overlap (1-1975:1-1977)
10 20 30 40 50 60
pF1KSD MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KSD ERSPAKRGRKSATVKP--VGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL
:::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_001 ERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KSD LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KSD CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KSD EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KSD VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
1930 1940 1950 1960 1970
>>NP_005648 (OMIM: 605230) tumor suppressor p53-binding (1972 aa)
initn: 11093 init1: 11093 opt: 12988 Z-score: 7966.5 bits: 1487.5 E(85289): 0
Smith-Waterman score: 12988; 99.9% identity (99.9% similar) in 1972 aa overlap (6-1975:1-1972)
10 20 30 40 50 60
pF1KSD MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
10 20 30 40 50
70 80 90 100 110 120
pF1KSD NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
660 670 680 690 700 710
730 740 750 760 770 780
pF1KSD MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KSD EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
780 790 800 810 820 830
850 860 870 880 890 900
pF1KSD PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
840 850 860 870 880 890
910 920 930 940 950 960
pF1KSD CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KSD KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KSD KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KSD VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KSD DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KSD SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KSD EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KSD FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KSD SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KSD GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KSD DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730
pF1KSD ERSPAKRGRKSATVKP--VGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL
:::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_005 ERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KSD LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KSD CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900 1910
pF1KSD EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG
1860 1870 1880 1890 1900 1910
1920 1930 1940 1950 1960 1970
pF1KSD VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
1920 1930 1940 1950 1960 1970
>>XP_011520288 (OMIM: 605230) PREDICTED: tumor suppresso (1700 aa)
initn: 11127 init1: 11127 opt: 11127 Z-score: 6827.2 bits: 1276.5 E(85289): 0
Smith-Waterman score: 11127; 100.0% identity (100.0% similar) in 1696 aa overlap (1-1696:1-1696)
10 20 30 40 50 60
pF1KSD MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD ERSPAKRGRKSATVKPVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLT
::::::::::::::::
XP_011 ERSPAKRGRKSATVKPGRHA
1690 1700
>>XP_011520287 (OMIM: 605230) PREDICTED: tumor suppresso (1927 aa)
initn: 10848 init1: 8949 opt: 8964 Z-score: 5501.0 bits: 1031.3 E(85289): 0
Smith-Waterman score: 12565; 97.4% identity (97.4% similar) in 1977 aa overlap (1-1975:1-1927)
10 20 30 40 50 60
pF1KSD MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGER
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVIT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVC
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKL--------------
1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KSD EEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKS
::::::::::::::::::::::::
XP_011 ------------------------------------RETAVPGPLGIEDISPNLSPDDKS
1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KSD FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKW
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KSD SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSA
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KSD GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAA
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660 1670 1680
pF1KSD DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEE
1580 1590 1600 1610 1620 1630
1690 1700 1710 1720 1730
pF1KSD ERSPAKRGRKSATVKP--VGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL
:::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_011 ERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFL
1640 1650 1660 1670 1680 1690
1740 1750 1760 1770 1780 1790
pF1KSD LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQ
1700 1710 1720 1730 1740 1750
1800 1810 1820 1830 1840 1850
pF1KSD CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLE
1760 1770 1780 1790 1800 1810
1860 1870 1880 1890 1900 1910
pF1KSD EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALG
1820 1830 1840 1850 1860 1870
1920 1930 1940 1950 1960 1970
pF1KSD VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
1880 1890 1900 1910 1920
>>XP_016878022 (OMIM: 605230) PREDICTED: tumor suppresso (1017 aa)
initn: 4847 init1: 4847 opt: 6742 Z-score: 4143.7 bits: 779.2 E(85289): 0
Smith-Waterman score: 6742; 99.8% identity (99.8% similar) in 1017 aa overlap (961-1975:1-1017)
940 950 960 970 980 990
pF1KSD IGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKL
::::::::::::::::::::::::::::::
XP_016 MSESMVETHDPILGSGKGDSGAAPDVDDKL
10 20 30
1000 1010 1020 1030 1040 1050
pF1KSD CLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQE
40 50 60 70 80 90
1060 1070 1080 1090 1100 1110
pF1KSD NEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQ
100 110 120 130 140 150
1120 1130 1140 1150 1160 1170
pF1KSD KMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPE
160 170 180 190 200 210
1180 1190 1200 1210 1220 1230
pF1KSD TVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEF
220 230 240 250 260 270
1240 1250 1260 1270 1280 1290
pF1KSD DMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECET
280 290 300 310 320 330
1300 1310 1320 1330 1340 1350
pF1KSD EVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTE
340 350 360 370 380 390
1360 1370 1380 1390 1400 1410
pF1KSD PADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPP
400 410 420 430 440 450
1420 1430 1440 1450 1460 1470
pF1KSD SRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEI
460 470 480 490 500 510
1480 1490 1500 1510 1520 1530
pF1KSD PFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYEC
520 530 540 550 560 570
1540 1550 1560 1570 1580 1590
pF1KSD DVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMA
580 590 600 610 620 630
1600 1610 1620 1630 1640 1650
pF1KSD VILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASSSS
640 650 660 670 680 690
1660 1670 1680 1690 1700
pF1KSD STTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRGRKSATVKP--VGAGEFVSPCES
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 STTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRGRKSATVKPGAVGAGEFVSPCES
700 710 720 730 740 750
1710 1720 1730 1740 1750 1760
pF1KSD GDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLPDGPTGSSEEEEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLPDGPTGSSEEEEEF
760 770 780 790 800 810
1770 1780 1790 1800 1810 1820
pF1KSD LEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPC
820 830 840 850 860 870
1830 1840 1850 1860 1870 1880
pF1KSD VSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFL
880 890 900 910 920 930
1890 1900 1910 1920 1930 1940
pF1KSD ELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQE
940 950 960 970 980 990
1950 1960 1970
pF1KSD WVIQCLIVGERIGFKQHPKYKHDYVSH
:::::::::::::::::::::::::::
XP_016 WVIQCLIVGERIGFKQHPKYKHDYVSH
1000 1010
1975 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:21:06 2016 done: Thu Nov 3 08:21:08 2016
Total Scan time: 19.700 Total Display time: 0.570
Function used was FASTA [36.3.4 Apr, 2011]