Result of FASTA (omim) for
pFN21ASDA1242
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1242, 493 aa
1>>>pF1KSDA1242 493 - 493 aa - 493 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0217+/-0.000492; mu= 10.0641+/- 0.030
mean_var=168.1969+/-36.120, 0's: 0 Z-trim(114.3): 292 B-trim: 2116 in 2/48
Lambda= 0.098893
statistics sampled from 23635 (24082) to 23635 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.282), width: 16
Scan time: 10.290
The best scores are: opt bits E(85289)
NP_057347 (OMIM: 603619) fizzy-related protein hom ( 493) 3300 483.7 5e-136
XP_005259630 (OMIM: 603619) PREDICTED: fizzy-relat ( 496) 3284 481.4 2.5e-135
NP_001129670 (OMIM: 603619) fizzy-related protein ( 496) 3284 481.4 2.5e-135
XP_016882352 (OMIM: 603619) PREDICTED: fizzy-relat ( 528) 3284 481.5 2.6e-135
NP_001129669 (OMIM: 603619) fizzy-related protein ( 404) 1856 277.6 4.6e-74
NP_001246 (OMIM: 603618) cell division cycle prote ( 499) 1094 169.0 2.8e-41
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 320 58.7 6e-08
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 320 58.7 6e-08
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 320 58.7 6e-08
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 320 58.7 6e-08
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 320 58.7 6.1e-08
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 320 58.7 6.1e-08
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 320 58.7 6.1e-08
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 320 58.7 6.1e-08
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 320 58.7 6.1e-08
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 320 58.7 6.1e-08
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 320 58.7 6.1e-08
XP_005247749 (OMIM: 610863,615185) PREDICTED: guan ( 340) 267 50.8 7.1e-06
NP_067642 (OMIM: 610863,615185) guanine nucleotide ( 340) 267 50.8 7.1e-06
XP_006713784 (OMIM: 610863,615185) PREDICTED: guan ( 340) 267 50.8 7.1e-06
NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 262 50.2 1.4e-05
XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 262 50.3 1.6e-05
NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 262 50.3 1.6e-05
XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 262 50.3 1.6e-05
XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 262 50.3 1.6e-05
NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 262 50.3 1.6e-05
XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 262 50.3 1.6e-05
XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 262 50.3 1.6e-05
NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 262 50.3 1.6e-05
XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 262 50.3 1.6e-05
XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577) 261 50.2 1.9e-05
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 257 49.4 1.9e-05
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 257 49.4 1.9e-05
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 257 49.4 1.9e-05
XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 255 49.0 2.1e-05
NP_001284500 (OMIM: 139130,145500,617024) guanine ( 339) 256 49.3 2.1e-05
NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340) 256 49.3 2.1e-05
XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 256 49.3 2.1e-05
XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 256 49.3 2.1e-05
NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 256 49.3 2.1e-05
NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 256 49.3 2.1e-05
XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 256 49.3 2.1e-05
XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540) 259 49.9 2.2e-05
NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 255 49.1 2.3e-05
NP_001269467 (OMIM: 139380,613065,616973) guanine ( 240) 247 47.8 4.1e-05
NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 252 48.9 4.2e-05
NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 252 48.9 4.2e-05
NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 252 48.9 4.2e-05
XP_005262629 (OMIM: 400033) PREDICTED: F-box-like/ ( 536) 252 48.9 4.3e-05
NP_005264 (OMIM: 139390) guanine nucleotide-bindin ( 340) 247 48.0 5.2e-05
>>NP_057347 (OMIM: 603619) fizzy-related protein homolog (493 aa)
initn: 3300 init1: 3300 opt: 3300 Z-score: 2563.0 bits: 483.7 E(85289): 5e-136
Smith-Waterman score: 3300; 100.0% identity (100.0% similar) in 493 aa overlap (1-493:1-493)
10 20 30 40 50 60
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
430 440 450 460 470 480
490
pF1KSD ESVSVLNLFTRIR
:::::::::::::
NP_057 ESVSVLNLFTRIR
490
>>XP_005259630 (OMIM: 603619) PREDICTED: fizzy-related p (496 aa)
initn: 3286 init1: 3225 opt: 3284 Z-score: 2550.7 bits: 481.4 E(85289): 2.5e-135
Smith-Waterman score: 3284; 99.4% identity (99.4% similar) in 496 aa overlap (1-493:1-496)
10 20 30 40 50 60
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
430 440 450 460 470 480
490
pF1KSD ---ESVSVLNLFTRIR
:::::::::::::
XP_005 VKWESVSVLNLFTRIR
490
>>NP_001129670 (OMIM: 603619) fizzy-related protein homo (496 aa)
initn: 3286 init1: 3225 opt: 3284 Z-score: 2550.7 bits: 481.4 E(85289): 2.5e-135
Smith-Waterman score: 3284; 99.4% identity (99.4% similar) in 496 aa overlap (1-493:1-496)
10 20 30 40 50 60
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
430 440 450 460 470 480
490
pF1KSD ---ESVSVLNLFTRIR
:::::::::::::
NP_001 VKWESVSVLNLFTRIR
490
>>XP_016882352 (OMIM: 603619) PREDICTED: fizzy-related p (528 aa)
initn: 3286 init1: 3225 opt: 3284 Z-score: 2550.3 bits: 481.5 E(85289): 2.6e-135
Smith-Waterman score: 3284; 99.4% identity (99.4% similar) in 496 aa overlap (1-493:33-528)
10 20 30
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRT
::::::::::::::::::::::::::::::
XP_016 GSCSGVWRAALVRPSPVDALTLPRAEPCLAMDQDYERRLLRQIVIQNENTMPRVTEMRRT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD LTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD YSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD SPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD LWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD TARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLAS
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD GGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLA
430 440 450 460 470 480
460 470 480 490
pF1KSD MSPDGEAIVTGAGDETLRFWNVFSKTRSTK---ESVSVLNLFTRIR
:::::::::::::::::::::::::::::: :::::::::::::
XP_016 MSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR
490 500 510 520
>>NP_001129669 (OMIM: 603619) fizzy-related protein homo (404 aa)
initn: 1856 init1: 1856 opt: 1856 Z-score: 1450.7 bits: 277.6 E(85289): 4.6e-74
Smith-Waterman score: 2518; 81.9% identity (81.9% similar) in 493 aa overlap (1-493:1-404)
10 20 30 40 50 60
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
:::::::::
NP_001 TPEKKGLFT---------------------------------------------------
190 200 210 220 230 240
pF1KSD APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
::::::::::::::::::::::
NP_001 --------------------------------------VTRLCDLSVEGDSVTSVGWSER
130 140 150
250 260 270 280 290 300
pF1KSD GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
160 170 180 190 200 210
310 320 330 340 350 360
pF1KSD PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
220 230 240 250 260 270
370 380 390 400 410 420
pF1KSD IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
280 290 300 310 320 330
430 440 450 460 470 480
pF1KSD SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
340 350 360 370 380 390
490
pF1KSD ESVSVLNLFTRIR
:::::::::::::
NP_001 ESVSVLNLFTRIR
400
>>NP_001246 (OMIM: 603618) cell division cycle protein 2 (499 aa)
initn: 1157 init1: 490 opt: 1094 Z-score: 862.0 bits: 169.0 E(85289): 2.8e-41
Smith-Waterman score: 1113; 41.3% identity (67.2% similar) in 458 aa overlap (29-473:58-473)
10 20 30 40 50
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPV-SSPSKHG-DRFIPSRAGAN
:: .:: : ..::: : ::.:: :..:.
NP_001 WQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQ
30 40 50 60 70 80
60 70 80 90 100
pF1KSD WSVNFHRIN-----ENEKSPSQNRKAKD-ATSDNGKDGLAYSALLKNELLGAGIEKVQD-
: .. :: ..:..... : : . :: : . . .:. : : : :.
NP_001 MEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFD-VEEAKILR--LSG----KPQNA
90 100 110 120 130 140
110 120 130 140 150 160
pF1KSD PQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTR
:. . ::. : .....: : :: :
NP_001 PEGYQNRLK------------VLYSQKATPG----------------------SSRKTCR
150 160
170 180 190 200 210 220
pF1KSD KISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEG
: ..: ..:::::...:.::::::::: :::.:.: . :::::: .... .: .. :
NP_001 YIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPG
170 180 190 200 210 220
230 240 250 260 270 280
pF1KSD DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR
. ..::.: ..:: .:::: .. ::.::. :.: . .:.::::.:.::. ::::::
NP_001 EYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSR
230 240 250 260 270 280
290 300 310 320 330 340
pF1KSD DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW----NHSSL
. : ..:.:. . :.:: ::::::.:. : . :::::::: . :: ....
NP_001 SGHIHHHDVRVAE-HHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW
290 300 310 320 330 340
350 360 370 380 390 400
pF1KSD SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL
:.: .:.: .::::.:: : : ..::.::::.:: ::.::. .: :. .:. ::::..
NP_001 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSI
350 360 370 380 390 400
410 420 430 440 450 460
pF1KSD AWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDE
:: : .::.: ::..:::...::::....::.: ::. ::: :.::::: .....:.::
NP_001 LWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADE
410 420 430 440 450 460
470 480 490
pF1KSD TLRFWNVFSKTRSTKESVSVLNLFTRIR
:::.: :
NP_001 TLRLWRCFELDPARRREREKASAAKSSLIHQGIR
470 480 490
>>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin (655 aa)
initn: 283 init1: 137 opt: 320 Z-score: 263.7 bits: 58.7 E(85289): 6e-08
Smith-Waterman score: 320; 31.9% identity (60.9% similar) in 207 aa overlap (196-397:31-228)
170 180 190 200 210 220
pF1KSD KPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTC-VYLWSACTSQVTRLCD
.: .:..: : : ::: . :
XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPN----CI
10 20 30 40 50
230 240 250 260 270 280
pF1KSD LSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--
.:. : . : :: . .:...:...: ...:: :.: : : :: : . .: ..
XP_016 MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY
60 70 80 90 100 110
290 300 310 320 330 340
pF1KSD AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW
.: ..:::.: : ::: : .:: : : :..: : . :::...:. . .:
XP_016 GEFVASGSQDTNIKLWDIRRKG--CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW
120 130 140 150 160 170
350 360 370 380 390 400
pF1KSD NHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS
. .. . .... : . :... . :... ::::: ..:: ::::. : ..::.
XP_016 DLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASG--SSDRTIRFWDLEKFQVVSCIEGEP
180 190 200 210 220 230
410 420 430 440 450 460
pF1KSD QVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVT
XP_016 GPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFS
240 250 260 270 280 290
>>XP_016878352 (OMIM: 602703,616212) PREDICTED: katanin (655 aa)
initn: 283 init1: 137 opt: 320 Z-score: 263.7 bits: 58.7 E(85289): 6e-08
Smith-Waterman score: 320; 31.9% identity (60.9% similar) in 207 aa overlap (196-397:31-228)
170 180 190 200 210 220
pF1KSD KPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTC-VYLWSACTSQVTRLCD
.: .:..: : : ::: . :
XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPN----CI
10 20 30 40 50
230 240 250 260 270 280
pF1KSD LSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--
.:. : . : :: . .:...:...: ...:: :.: : : :: : . .: ..
XP_016 MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY
60 70 80 90 100 110
290 300 310 320 330 340
pF1KSD AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW
.: ..:::.: : ::: : .:: : : :..: : . :::...:. . .:
XP_016 GEFVASGSQDTNIKLWDIRRKG--CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW
120 130 140 150 160 170
350 360 370 380 390 400
pF1KSD NHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS
. .. . .... : . :... . :... ::::: ..:: ::::. : ..::.
XP_016 DLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASG--SSDRTIRFWDLEKFQVVSCIEGEP
180 190 200 210 220 230
410 420 430 440 450 460
pF1KSD QVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVT
XP_016 GPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFS
240 250 260 270 280 290
>>NP_005877 (OMIM: 602703,616212) katanin p80 WD40 repea (655 aa)
initn: 283 init1: 137 opt: 320 Z-score: 263.7 bits: 58.7 E(85289): 6e-08
Smith-Waterman score: 320; 31.9% identity (60.9% similar) in 207 aa overlap (196-397:31-228)
170 180 190 200 210 220
pF1KSD KPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTC-VYLWSACTSQVTRLCD
.: .:..: : : ::: . :
NP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPN----CI
10 20 30 40 50
230 240 250 260 270 280
pF1KSD LSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--
.:. : . : :: . .:...:...: ...:: :.: : : :: : . .: ..
NP_005 MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY
60 70 80 90 100 110
290 300 310 320 330 340
pF1KSD AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW
.: ..:::.: : ::: : .:: : : :..: : . :::...:. . .:
NP_005 GEFVASGSQDTNIKLWDIRRKG--CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW
120 130 140 150 160 170
350 360 370 380 390 400
pF1KSD NHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS
. .. . .... : . :... . :... ::::: ..:: ::::. : ..::.
NP_005 DLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASG--SSDRTIRFWDLEKFQVVSCIEGEP
180 190 200 210 220 230
410 420 430 440 450 460
pF1KSD QVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVT
NP_005 GPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFS
240 250 260 270 280 290
>>XP_006721186 (OMIM: 602703,616212) PREDICTED: katanin (658 aa)
initn: 283 init1: 137 opt: 320 Z-score: 263.7 bits: 58.7 E(85289): 6e-08
Smith-Waterman score: 320; 31.9% identity (60.9% similar) in 207 aa overlap (196-397:31-228)
170 180 190 200 210 220
pF1KSD KPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTC-VYLWSACTSQVTRLCD
.: .:..: : : ::: . :
XP_006 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPN----CI
10 20 30 40 50
230 240 250 260 270 280
pF1KSD LSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--
.:. : . : :: . .:...:...: ...:: :.: : : :: : . .: ..
XP_006 MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY
60 70 80 90 100 110
290 300 310 320 330 340
pF1KSD AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW
.: ..:::.: : ::: : .:: : : :..: : . :::...:. . .:
XP_006 GEFVASGSQDTNIKLWDIRRKG--CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW
120 130 140 150 160 170
350 360 370 380 390 400
pF1KSD NHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS
. .. . .... : . :... . :... ::::: ..:: ::::. : ..::.
XP_006 DLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASG--SSDRTIRFWDLEKFQVVSCIEGEP
180 190 200 210 220 230
410 420 430 440 450 460
pF1KSD QVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVT
XP_006 GPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFS
240 250 260 270 280 290
493 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:30:38 2016 done: Thu Nov 3 05:30:40 2016
Total Scan time: 10.290 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]