Result of FASTA (omim) for
pFN21ASDA0317
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0317, 823 aa
1>>>pF1KSDA0317 823 - 823 aa - 823 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7781+/-0.000429; mu= 17.9100+/- 0.027
mean_var=79.5555+/-15.778, 0's: 0 Z-trim(111.5): 267 B-trim: 285 in 1/50
Lambda= 0.143793
statistics sampled from 19799 (20078) to 19799 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.235), width: 16
Scan time: 11.480
The best scores are: opt bits E(85289)
XP_011535717 (OMIM: 615380) PREDICTED: apoptosis-r ( 823) 5556 1163.1 0
NP_001034568 (OMIM: 615380) apoptosis-resistant E3 ( 823) 5556 1163.1 0
XP_006720407 (OMIM: 615380) PREDICTED: apoptosis-r ( 813) 5000 1047.8 0
XP_005268301 (OMIM: 615380) PREDICTED: apoptosis-r ( 662) 4469 937.6 0
XP_011535719 (OMIM: 615380) PREDICTED: apoptosis-r ( 662) 4469 937.6 0
XP_011535718 (OMIM: 615380) PREDICTED: apoptosis-r ( 763) 3634 764.4 0
XP_016884695 (OMIM: 300697,300706) PREDICTED: E3 u (4367) 716 159.5 3e-37
NP_113584 (OMIM: 300697,300706) E3 ubiquitin-prote (4374) 716 159.5 3e-37
XP_005262022 (OMIM: 300697,300706) PREDICTED: E3 u (4374) 716 159.5 3e-37
XP_016884694 (OMIM: 300697,300706) PREDICTED: E3 u (4377) 716 159.5 3e-37
XP_016884693 (OMIM: 300697,300706) PREDICTED: E3 u (4418) 716 159.5 3.1e-37
XP_011529053 (OMIM: 300697,300706) PREDICTED: E3 u (4457) 716 159.5 3.1e-37
XP_011529049 (OMIM: 300697,300706) PREDICTED: E3 u (4457) 716 159.5 3.1e-37
XP_016884690 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 716 159.5 3.1e-37
XP_016884687 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 716 159.5 3.1e-37
XP_016884691 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 716 159.5 3.1e-37
XP_016884688 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 716 159.5 3.1e-37
XP_016884689 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 716 159.5 3.1e-37
XP_016884692 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 716 159.5 3.1e-37
XP_016884686 (OMIM: 300697,300706) PREDICTED: E3 u (4468) 716 159.5 3.1e-37
XP_016884685 (OMIM: 300697,300706) PREDICTED: E3 u (4484) 716 159.5 3.1e-37
XP_016884684 (OMIM: 300697,300706) PREDICTED: E3 u (4485) 716 159.5 3.1e-37
XP_016884683 (OMIM: 300697,300706) PREDICTED: E3 u (4486) 716 159.5 3.1e-37
XP_016884682 (OMIM: 300697,300706) PREDICTED: E3 u (4494) 716 159.5 3.1e-37
XP_016884681 (OMIM: 300697,300706) PREDICTED: E3 u (4500) 716 159.5 3.1e-37
XP_016884680 (OMIM: 300697,300706) PREDICTED: E3 u (4501) 716 159.5 3.1e-37
NP_955456 (OMIM: 602308) NEDD4-like E3 ubiquitin-p ( 431) 685 152.5 3.8e-36
NP_001257382 (OMIM: 602308) NEDD4-like E3 ubiquiti ( 754) 685 152.6 6.1e-36
XP_011521128 (OMIM: 602308) PREDICTED: NEDD4-like ( 754) 685 152.6 6.1e-36
XP_016878369 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 685 152.6 6.8e-36
NP_008945 (OMIM: 602308) NEDD4-like E3 ubiquitin-p ( 870) 685 152.6 6.8e-36
XP_016878370 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 685 152.6 6.8e-36
XP_011521125 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 685 152.6 6.8e-36
XP_016878368 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 685 152.6 6.8e-36
XP_011521127 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 685 152.6 6.8e-36
NP_001257383 (OMIM: 602308) NEDD4-like E3 ubiquiti ( 870) 685 152.6 6.8e-36
XP_011527381 (OMIM: 606409,613385) PREDICTED: E3 u ( 692) 675 150.5 2.4e-35
XP_005260627 (OMIM: 606409,613385) PREDICTED: E3 u ( 692) 675 150.5 2.4e-35
NP_001244067 (OMIM: 606409,613385) E3 ubiquitin-pr ( 752) 675 150.5 2.6e-35
XP_016883580 (OMIM: 606409,613385) PREDICTED: E3 u ( 752) 675 150.5 2.6e-35
NP_001311127 (OMIM: 606409,613385) E3 ubiquitin-pr ( 862) 675 150.6 2.9e-35
NP_113671 (OMIM: 606409,613385) E3 ubiquitin-prote ( 862) 675 150.6 2.9e-35
XP_016883579 (OMIM: 606409,613385) PREDICTED: E3 u ( 900) 675 150.6 3e-35
XP_016883578 (OMIM: 606409,613385) PREDICTED: E3 u ( 903) 675 150.6 3e-35
NP_001311126 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903) 675 150.6 3e-35
NP_001244066 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903) 675 150.6 3e-35
XP_016868484 (OMIM: 602307) PREDICTED: NEDD4-like ( 743) 644 144.1 2.2e-33
XP_016868485 (OMIM: 602307) PREDICTED: NEDD4-like ( 743) 644 144.1 2.2e-33
XP_016868482 (OMIM: 602307) PREDICTED: NEDD4-like ( 921) 644 144.2 2.6e-33
XP_005250818 (OMIM: 602307) PREDICTED: NEDD4-like ( 921) 644 144.2 2.6e-33
>>XP_011535717 (OMIM: 615380) PREDICTED: apoptosis-resis (823 aa)
initn: 5556 init1: 5556 opt: 5556 Z-score: 6226.8 bits: 1163.1 E(85289): 0
Smith-Waterman score: 5556; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823)
10 20 30 40 50 60
pF1KSD MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
730 740 750 760 770 780
790 800 810 820
pF1KSD HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
:::::::::::::::::::::::::::::::::::::::::::
XP_011 HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
790 800 810 820
>>NP_001034568 (OMIM: 615380) apoptosis-resistant E3 ubi (823 aa)
initn: 5556 init1: 5556 opt: 5556 Z-score: 6226.8 bits: 1163.1 E(85289): 0
Smith-Waterman score: 5556; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823)
10 20 30 40 50 60
pF1KSD MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
730 740 750 760 770 780
790 800 810 820
pF1KSD HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
:::::::::::::::::::::::::::::::::::::::::::
NP_001 HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
790 800 810 820
>>XP_006720407 (OMIM: 615380) PREDICTED: apoptosis-resis (813 aa)
initn: 4998 init1: 4998 opt: 5000 Z-score: 5603.6 bits: 1047.8 E(85289): 0
Smith-Waterman score: 5456; 98.8% identity (98.8% similar) in 823 aa overlap (1-823:1-813)
10 20 30 40 50 60
pF1KSD MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_006 KVSWDWKDPYE----------LFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
70 80 90 100 110
130 140 150 160 170 180
pF1KSD PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
660 670 680 690 700 710
730 740 750 760 770 780
pF1KSD VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
720 730 740 750 760 770
790 800 810 820
pF1KSD HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
:::::::::::::::::::::::::::::::::::::::::::
XP_006 HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
780 790 800 810
>>XP_005268301 (OMIM: 615380) PREDICTED: apoptosis-resis (662 aa)
initn: 4469 init1: 4469 opt: 4469 Z-score: 5009.6 bits: 937.6 E(85289): 0
Smith-Waterman score: 4469; 100.0% identity (100.0% similar) in 662 aa overlap (162-823:1-662)
140 150 160 170 180 190
pF1KSD VRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVP
::::::::::::::::::::::::::::::
XP_005 MVVPSKTKIVCHFSTLVLTCGQPHTLQIVP
10 20 30
200 210 220 230 240 250
pF1KSD RDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHS
40 50 60 70 80 90
260 270 280 290 300 310
pF1KSD RGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTP
100 110 120 130 140 150
320 330 340 350 360 370
pF1KSD WHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKI
160 170 180 190 200 210
380 390 400 410 420 430
pF1KSD IPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHK
220 230 240 250 260 270
440 450 460 470 480 490
pF1KSD NIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNF
280 290 300 310 320 330
500 510 520 530 540 550
pF1KSD EVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKM
340 350 360 370 380 390
560 570 580 590 600 610
pF1KSD YEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVC
400 410 420 430 440 450
620 630 640 650 660 670
pF1KSD FILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQ
460 470 480 490 500 510
680 690 700 710 720 730
pF1KSD VKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREK
520 530 540 550 560 570
740 750 760 770 780 790
pF1KSD VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCF
580 590 600 610 620 630
800 810 820
pF1KSD NQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
::::::::::::::::::::::::::::::::
XP_005 NQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
640 650 660
>>XP_011535719 (OMIM: 615380) PREDICTED: apoptosis-resis (662 aa)
initn: 4469 init1: 4469 opt: 4469 Z-score: 5009.6 bits: 937.6 E(85289): 0
Smith-Waterman score: 4469; 100.0% identity (100.0% similar) in 662 aa overlap (162-823:1-662)
140 150 160 170 180 190
pF1KSD VRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVP
::::::::::::::::::::::::::::::
XP_011 MVVPSKTKIVCHFSTLVLTCGQPHTLQIVP
10 20 30
200 210 220 230 240 250
pF1KSD RDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHS
40 50 60 70 80 90
260 270 280 290 300 310
pF1KSD RGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTP
100 110 120 130 140 150
320 330 340 350 360 370
pF1KSD WHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKI
160 170 180 190 200 210
380 390 400 410 420 430
pF1KSD IPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHK
220 230 240 250 260 270
440 450 460 470 480 490
pF1KSD NIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNF
280 290 300 310 320 330
500 510 520 530 540 550
pF1KSD EVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKM
340 350 360 370 380 390
560 570 580 590 600 610
pF1KSD YEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVC
400 410 420 430 440 450
620 630 640 650 660 670
pF1KSD FILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQ
460 470 480 490 500 510
680 690 700 710 720 730
pF1KSD VKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREK
520 530 540 550 560 570
740 750 760 770 780 790
pF1KSD VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCF
580 590 600 610 620 630
800 810 820
pF1KSD NQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
::::::::::::::::::::::::::::::::
XP_011 NQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
640 650 660
>>XP_011535718 (OMIM: 615380) PREDICTED: apoptosis-resis (763 aa)
initn: 5136 init1: 3634 opt: 3634 Z-score: 4072.5 bits: 764.4 E(85289): 0
Smith-Waterman score: 5020; 92.7% identity (92.7% similar) in 823 aa overlap (1-823:1-763)
10 20 30 40 50 60
pF1KSD MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQAL----
490 500 510 520 530
550 560 570 580 590 600
pF1KSD PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
::::
XP_011 --------------------------------------------------------YFET
540
610 620 630 640 650 660
pF1KSD DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
550 560 570 580 590 600
670 680 690 700 710 720
pF1KSD NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
610 620 630 640 650 660
730 740 750 760 770 780
pF1KSD VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
670 680 690 700 710 720
790 800 810 820
pF1KSD HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
:::::::::::::::::::::::::::::::::::::::::::
XP_011 HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
730 740 750 760
>>XP_016884695 (OMIM: 300697,300706) PREDICTED: E3 ubiqu (4367 aa)
initn: 596 init1: 197 opt: 716 Z-score: 789.6 bits: 159.5 E(85289): 3e-37
Smith-Waterman score: 723; 34.6% identity (67.2% similar) in 396 aa overlap (439-822:3987-4366)
410 420 430 440 450 460
pF1KSD PPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSR
:. : ..:..::... . ....: :
XP_016 TVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRR
3960 3970 3980 3990 4000 4010
470 480 490 500 510 520
pF1KSD HALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTR
..:.: . . : . .. . .::. ::. : :: :::. .: . .:. :: :
XP_016 DHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALF-R
4020 4030 4040 4050 4060 4070
530 540 550 560 570 580
pF1KSD FSDNNQALVHPNPNR---PAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFL
: .... ::. : :: ....:.::.:.: .:.. .:.. :::::
XP_016 TSPGDRVTYTINPSSHCNPNHL--SYFKFVGRIVAKAVYDN-------RLLECYFTRSFY
4080 4090 4100 4110 4120
590 600 610 620 630 640
pF1KSD AQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKVVELM
.:.: ..: .:..: .::.. : ..:.::.: . .:.:. : .. : . .: .:
XP_016 KHILGKSVRYTDMESEDYHFYQGLV-YLLENDVSTLGYDLTFSTE-VQEFG-VCEVRDLK
4130 4140 4150 4160 4170 4180
650 660 670 680 690 700
pF1KSD TGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELL
.::. ::. :: :..:. :.:... ..... ::.:. :..:. :..:: :.:::::
XP_016 PNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELL
4190 4200 4210 4220 4230 4240
710 720 730 740 750 760
pF1KSD MCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPP
. : :...:.:... ... ..::: .. :. : . :..:::.::.:..:
XP_016 ISGLPTIDIDDLKSNTEY--HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPL
4250 4260 4270 4280 4290 4300
770 780 790 800 810
pF1KSD GGFAAL-----CPSFQIIAAPTHST--LPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG
::::: .::: .:: ::.:::::::: ::.:.:.:....:: :::.:
XP_016 QGFAALEGMNGIQKFQI-HRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC
4310 4320 4330 4340 4350 4360
820
pF1KSD CEGFGML
::::.
XP_016 SEGFGLA
>>NP_113584 (OMIM: 300697,300706) E3 ubiquitin-protein l (4374 aa)
initn: 596 init1: 197 opt: 716 Z-score: 789.6 bits: 159.5 E(85289): 3e-37
Smith-Waterman score: 723; 34.6% identity (67.2% similar) in 396 aa overlap (439-822:3994-4373)
410 420 430 440 450 460
pF1KSD PPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSR
:. : ..:..::... . ....: :
NP_113 TVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRR
3970 3980 3990 4000 4010 4020
470 480 490 500 510 520
pF1KSD HALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTR
..:.: . . : . .. . .::. ::. : :: :::. .: . .:. :: :
NP_113 DHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALF-R
4030 4040 4050 4060 4070 4080
530 540 550 560 570 580
pF1KSD FSDNNQALVHPNPNR---PAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFL
: .... ::. : :: ....:.::.:.: .:.. .:.. :::::
NP_113 TSPGDRVTYTINPSSHCNPNHL--SYFKFVGRIVAKAVYDN-------RLLECYFTRSFY
4090 4100 4110 4120 4130
590 600 610 620 630 640
pF1KSD AQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKVVELM
.:.: ..: .:..: .::.. : ..:.::.: . .:.:. : .. : . .: .:
NP_113 KHILGKSVRYTDMESEDYHFYQGLV-YLLENDVSTLGYDLTFSTE-VQEFG-VCEVRDLK
4140 4150 4160 4170 4180 4190
650 660 670 680 690 700
pF1KSD TGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELL
.::. ::. :: :..:. :.:... ..... ::.:. :..:. :..:: :.:::::
NP_113 PNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELL
4200 4210 4220 4230 4240 4250
710 720 730 740 750 760
pF1KSD MCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPP
. : :...:.:... ... ..::: .. :. : . :..:::.::.:..:
NP_113 ISGLPTIDIDDLKSNTEY--HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPL
4260 4270 4280 4290 4300
770 780 790 800 810
pF1KSD GGFAAL-----CPSFQIIAAPTHST--LPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG
::::: .::: .:: ::.:::::::: ::.:.:.:....:: :::.:
NP_113 QGFAALEGMNGIQKFQI-HRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC
4310 4320 4330 4340 4350 4360
820
pF1KSD CEGFGML
::::.
NP_113 SEGFGLA
4370
>>XP_005262022 (OMIM: 300697,300706) PREDICTED: E3 ubiqu (4374 aa)
initn: 596 init1: 197 opt: 716 Z-score: 789.6 bits: 159.5 E(85289): 3e-37
Smith-Waterman score: 723; 34.6% identity (67.2% similar) in 396 aa overlap (439-822:3994-4373)
410 420 430 440 450 460
pF1KSD PPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSR
:. : ..:..::... . ....: :
XP_005 TVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRR
3970 3980 3990 4000 4010 4020
470 480 490 500 510 520
pF1KSD HALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTR
..:.: . . : . .. . .::. ::. : :: :::. .: . .:. :: :
XP_005 DHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALF-R
4030 4040 4050 4060 4070 4080
530 540 550 560 570 580
pF1KSD FSDNNQALVHPNPNR---PAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFL
: .... ::. : :: ....:.::.:.: .:.. .:.. :::::
XP_005 TSPGDRVTYTINPSSHCNPNHL--SYFKFVGRIVAKAVYDN-------RLLECYFTRSFY
4090 4100 4110 4120 4130
590 600 610 620 630 640
pF1KSD AQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKVVELM
.:.: ..: .:..: .::.. : ..:.::.: . .:.:. : .. : . .: .:
XP_005 KHILGKSVRYTDMESEDYHFYQGLV-YLLENDVSTLGYDLTFSTE-VQEFG-VCEVRDLK
4140 4150 4160 4170 4180 4190
650 660 670 680 690 700
pF1KSD TGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELL
.::. ::. :: :..:. :.:... ..... ::.:. :..:. :..:: :.:::::
XP_005 PNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELL
4200 4210 4220 4230 4240 4250
710 720 730 740 750 760
pF1KSD MCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPP
. : :...:.:... ... ..::: .. :. : . :..:::.::.:..:
XP_005 ISGLPTIDIDDLKSNTEY--HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPL
4260 4270 4280 4290 4300
770 780 790 800 810
pF1KSD GGFAAL-----CPSFQIIAAPTHST--LPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG
::::: .::: .:: ::.:::::::: ::.:.:.:....:: :::.:
XP_005 QGFAALEGMNGIQKFQI-HRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC
4310 4320 4330 4340 4350 4360
820
pF1KSD CEGFGML
::::.
XP_005 SEGFGLA
4370
>>XP_016884694 (OMIM: 300697,300706) PREDICTED: E3 ubiqu (4377 aa)
initn: 596 init1: 197 opt: 716 Z-score: 789.6 bits: 159.5 E(85289): 3e-37
Smith-Waterman score: 723; 34.6% identity (67.2% similar) in 396 aa overlap (439-822:3997-4376)
410 420 430 440 450 460
pF1KSD PPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSR
:. : ..:..::... . ....: :
XP_016 TVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRR
3970 3980 3990 4000 4010 4020
470 480 490 500 510 520
pF1KSD HALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTR
..:.: . . : . .. . .::. ::. : :: :::. .: . .:. :: :
XP_016 DHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALF-R
4030 4040 4050 4060 4070 4080
530 540 550 560 570 580
pF1KSD FSDNNQALVHPNPNR---PAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFL
: .... ::. : :: ....:.::.:.: .:.. .:.. :::::
XP_016 TSPGDRVTYTINPSSHCNPNHL--SYFKFVGRIVAKAVYDN-------RLLECYFTRSFY
4090 4100 4110 4120 4130
590 600 610 620 630 640
pF1KSD AQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKVVELM
.:.: ..: .:..: .::.. : ..:.::.: . .:.:. : .. : . .: .:
XP_016 KHILGKSVRYTDMESEDYHFYQGLV-YLLENDVSTLGYDLTFSTE-VQEFG-VCEVRDLK
4140 4150 4160 4170 4180 4190
650 660 670 680 690 700
pF1KSD TGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELL
.::. ::. :: :..:. :.:... ..... ::.:. :..:. :..:: :.:::::
XP_016 PNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELL
4200 4210 4220 4230 4240 4250
710 720 730 740 750 760
pF1KSD MCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPP
. : :...:.:... ... ..::: .. :. : . :..:::.::.:..:
XP_016 ISGLPTIDIDDLKSNTEY--HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPL
4260 4270 4280 4290 4300 4310
770 780 790 800 810
pF1KSD GGFAAL-----CPSFQIIAAPTHST--LPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG
::::: .::: .:: ::.:::::::: ::.:.:.:....:: :::.:
XP_016 QGFAALEGMNGIQKFQI-HRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC
4320 4330 4340 4350 4360 4370
820
pF1KSD CEGFGML
::::.
XP_016 SEGFGLA
823 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:15:09 2016 done: Thu Nov 3 01:15:11 2016
Total Scan time: 11.480 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]