Result of FASTA (omim) for
pFN21AA1047
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1047, 2337 aa
1>>>pF1KA1047 2337 - 2337 aa - 2337 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.1516+/-0.000421; mu= -4.7212+/- 0.026
mean_var=386.5173+/-80.647, 0's: 0 Z-trim(122.5): 68 B-trim: 1925 in 1/61
Lambda= 0.065236
statistics sampled from 40756 (40824) to 40756 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.479), width: 16
Scan time: 19.920
The best scores are: opt bits E(85289)
XP_011522388 (OMIM: 600849) PREDICTED: nuclear rec (2337) 15543 1478.7 0
NP_001177369 (OMIM: 600849) nuclear receptor corep (2337) 15543 1478.7 0
XP_016880908 (OMIM: 600849) PREDICTED: nuclear rec (2347) 13665 1301.9 0
XP_016880909 (OMIM: 600849) PREDICTED: nuclear rec (2331) 12595 1201.2 0
XP_016880905 (OMIM: 600849) PREDICTED: nuclear rec (2456) 12357 1178.9 0
XP_006721667 (OMIM: 600849) PREDICTED: nuclear rec (2456) 12357 1178.9 0
XP_016880904 (OMIM: 600849) PREDICTED: nuclear rec (2465) 10481 1002.3 0
XP_005256931 (OMIM: 600849) PREDICTED: nuclear rec (2466) 10479 1002.1 0
XP_016880906 (OMIM: 600849) PREDICTED: nuclear rec (2450) 9409 901.4 0
XP_011522387 (OMIM: 600849) PREDICTED: nuclear rec (2405) 8775 841.7 0
XP_016880907 (OMIM: 600849) PREDICTED: nuclear rec (2404) 8758 840.1 0
NP_006302 (OMIM: 600849) nuclear receptor corepres (2440) 7525 724.1 5.2e-207
XP_016880903 (OMIM: 600849) PREDICTED: nuclear rec (2514) 6903 665.6 2.2e-189
XP_016880900 (OMIM: 600849) PREDICTED: nuclear rec (2514) 6903 665.6 2.2e-189
XP_016880899 (OMIM: 600849) PREDICTED: nuclear rec (2514) 6903 665.6 2.2e-189
XP_016880901 (OMIM: 600849) PREDICTED: nuclear rec (2514) 6903 665.6 2.2e-189
XP_016880898 (OMIM: 600849) PREDICTED: nuclear rec (2514) 6903 665.6 2.2e-189
XP_016880902 (OMIM: 600849) PREDICTED: nuclear rec (2514) 6903 665.6 2.2e-189
XP_005256929 (OMIM: 600849) PREDICTED: nuclear rec (2514) 6903 665.6 2.2e-189
NP_001177367 (OMIM: 600849) nuclear receptor corep ( 914) 5821 563.4 4.5e-159
XP_011522386 (OMIM: 600849) PREDICTED: nuclear rec (2523) 5591 542.1 3.3e-152
XP_006721666 (OMIM: 600849) PREDICTED: nuclear rec (2511) 5590 542.0 3.5e-152
XP_005256930 (OMIM: 600849) PREDICTED: nuclear rec (2508) 5589 541.9 3.8e-152
XP_016880892 (OMIM: 600849) PREDICTED: nuclear rec (2515) 5589 541.9 3.8e-152
XP_005256928 (OMIM: 600849) PREDICTED: nuclear rec (2515) 5589 541.9 3.8e-152
XP_016880894 (OMIM: 600849) PREDICTED: nuclear rec (2515) 5589 541.9 3.8e-152
XP_016880896 (OMIM: 600849) PREDICTED: nuclear rec (2515) 5589 541.9 3.8e-152
XP_016880895 (OMIM: 600849) PREDICTED: nuclear rec (2515) 5589 541.9 3.8e-152
XP_016880893 (OMIM: 600849) PREDICTED: nuclear rec (2515) 5589 541.9 3.8e-152
XP_016880897 (OMIM: 600849) PREDICTED: nuclear rec (2515) 5589 541.9 3.8e-152
XP_005256925 (OMIM: 600849) PREDICTED: nuclear rec (2523) 5589 541.9 3.8e-152
XP_016880891 (OMIM: 600849) PREDICTED: nuclear rec (2523) 5589 541.9 3.8e-152
XP_016880890 (OMIM: 600849) PREDICTED: nuclear rec (2523) 5589 541.9 3.8e-152
XP_016880889 (OMIM: 600849) PREDICTED: nuclear rec (2523) 5589 541.9 3.8e-152
XP_006721665 (OMIM: 600849) PREDICTED: nuclear rec (2523) 5589 541.9 3.8e-152
XP_011522385 (OMIM: 600849) PREDICTED: nuclear rec (2524) 5589 541.9 3.8e-152
XP_005256923 (OMIM: 600849) PREDICTED: nuclear rec (2524) 5589 541.9 3.8e-152
XP_016880887 (OMIM: 600849) PREDICTED: nuclear rec (2524) 5589 541.9 3.8e-152
XP_006721664 (OMIM: 600849) PREDICTED: nuclear rec (2524) 5589 541.9 3.8e-152
XP_016880885 (OMIM: 600849) PREDICTED: nuclear rec (2524) 5589 541.9 3.8e-152
XP_016880888 (OMIM: 600849) PREDICTED: nuclear rec (2524) 5589 541.9 3.8e-152
XP_016880886 (OMIM: 600849) PREDICTED: nuclear rec (2524) 5589 541.9 3.8e-152
XP_005256932 (OMIM: 600849) PREDICTED: nuclear rec (2448) 5047 490.9 8.4e-137
NP_001070729 (OMIM: 600848) nuclear receptor corep (2458) 3013 299.4 3.6e-79
NP_001193583 (OMIM: 600848) nuclear receptor corep (2504) 3013 299.4 3.6e-79
NP_006303 (OMIM: 600848) nuclear receptor corepres (2514) 2808 280.2 2.3e-73
NP_055971 (OMIM: 607675) REST corepressor 1 [Homo ( 485) 318 45.3 0.0022
>>XP_011522388 (OMIM: 600849) PREDICTED: nuclear recepto (2337 aa)
initn: 15543 init1: 15543 opt: 15543 Z-score: 7916.1 bits: 1478.7 E(85289): 0
Smith-Waterman score: 15543; 100.0% identity (100.0% similar) in 2337 aa overlap (1-2337:1-2337)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 ENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 PSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 ADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 PCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREW
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 EVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 YLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 RAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 GSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRAT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 TESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQES
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 RKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 PVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 SPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA1 AMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA1 PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKER
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA1 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA1 TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKEISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKEISS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA1 HRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQES
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA1 PSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQN
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA1 SPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVS
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA1 SEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSP
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA1 MVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGL
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA1 EDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCK
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KA1 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330
pF1KA1 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
2290 2300 2310 2320 2330
>>NP_001177369 (OMIM: 600849) nuclear receptor corepress (2337 aa)
initn: 15543 init1: 15543 opt: 15543 Z-score: 7916.1 bits: 1478.7 E(85289): 0
Smith-Waterman score: 15543; 100.0% identity (100.0% similar) in 2337 aa overlap (1-2337:1-2337)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 ENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 PSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 ADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 PCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREW
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 EVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 YLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 RAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 GSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRAT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 TESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQES
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 RKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 PVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 SPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA1 AMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA1 PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKER
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA1 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA1 TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKEISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKEISS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA1 HRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQES
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA1 PSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQN
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA1 SPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVS
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA1 SEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSP
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA1 MVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGL
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA1 EDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCK
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KA1 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330
pF1KA1 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
2290 2300 2310 2320 2330
>>XP_016880908 (OMIM: 600849) PREDICTED: nuclear recepto (2347 aa)
initn: 14059 init1: 12164 opt: 13665 Z-score: 6960.8 bits: 1301.9 E(85289): 0
Smith-Waterman score: 15503; 99.6% identity (99.6% similar) in 2347 aa overlap (1-2337:1-2347)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKT---------NQVMRKKLIL
::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTGVPARRMMKNQVMRKKLIL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQ-IARPSQEEKVEEKEEDKAEKTEKKEE
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_016 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKEEDKAEKTEKKEE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KA1 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KA1 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KA1 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KA1 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KA1 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KA1 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KA1 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA1 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KA1 DVSKTKEISSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVSKTKEISSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGP
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KA1 LHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTP
1930 1940 1950 1960 1970 1980
1980 1990 2000 2010 2020 2030
pF1KA1 QQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRP
1990 2000 2010 2020 2030 2040
2040 2050 2060 2070 2080 2090
pF1KA1 GKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPS
2050 2060 2070 2080 2090 2100
2100 2110 2120 2130 2140 2150
pF1KA1 FFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHS
2110 2120 2130 2140 2150 2160
2160 2170 2180 2190 2200 2210
pF1KA1 FADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGD
2170 2180 2190 2200 2210 2220
2220 2230 2240 2250 2260 2270
pF1KA1 PSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWED
2230 2240 2250 2260 2270 2280
2280 2290 2300 2310 2320 2330
pF1KA1 RPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYE
2290 2300 2310 2320 2330 2340
pF1KA1 TLSDSDD
:::::::
XP_016 TLSDSDD
>>XP_016880909 (OMIM: 600849) PREDICTED: nuclear recepto (2331 aa)
initn: 12747 init1: 10609 opt: 12595 Z-score: 6416.6 bits: 1201.2 E(85289): 0
Smith-Waterman score: 15356; 98.9% identity (98.9% similar) in 2347 aa overlap (1-2337:1-2331)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKT---------NQVMRKKLIL
::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTGVPARRMMKNQVMRKKLIL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQ-IARPSQEEKVEEKEEDKAEKTEKKEE
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_016 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKEEDKAEKTEKKEE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
::::::::::::::::: :::::::::::::::::::::::::::
XP_016 DEDIEASNEEENPEDSE----------------VEAVKPSEDSPENATSRGNTEPAVELE
730 740 750 760
780 790 800 810 820 830
pF1KA1 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
770 780 790 800 810 820
840 850 860 870 880 890
pF1KA1 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
830 840 850 860 870 880
900 910 920 930 940 950
pF1KA1 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KA1 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KA1 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KA1 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
pF1KA1 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
pF1KA1 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KA1 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
pF1KA1 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
1310 1320 1330 1340 1350 1360
1380 1390 1400 1410 1420 1430
pF1KA1 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
1370 1380 1390 1400 1410 1420
1440 1450 1460 1470 1480 1490
pF1KA1 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
1430 1440 1450 1460 1470 1480
1500 1510 1520 1530 1540 1550
pF1KA1 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
1490 1500 1510 1520 1530 1540
1560 1570 1580 1590 1600 1610
pF1KA1 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
1550 1560 1570 1580 1590 1600
1620 1630 1640 1650 1660 1670
pF1KA1 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
1610 1620 1630 1640 1650 1660
1680 1690 1700 1710 1720 1730
pF1KA1 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
1670 1680 1690 1700 1710 1720
1740 1750 1760 1770 1780 1790
pF1KA1 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
1730 1740 1750 1760 1770 1780
1800 1810 1820 1830 1840 1850
pF1KA1 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
1790 1800 1810 1820 1830 1840
1860 1870 1880 1890 1900 1910
pF1KA1 DVSKTKEISSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVSKTKEISSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGP
1850 1860 1870 1880 1890 1900
1920 1930 1940 1950 1960 1970
pF1KA1 LHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTP
1910 1920 1930 1940 1950 1960
1980 1990 2000 2010 2020 2030
pF1KA1 QQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRP
1970 1980 1990 2000 2010 2020
2040 2050 2060 2070 2080 2090
pF1KA1 GKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPS
2030 2040 2050 2060 2070 2080
2100 2110 2120 2130 2140 2150
pF1KA1 FFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHS
2090 2100 2110 2120 2130 2140
2160 2170 2180 2190 2200 2210
pF1KA1 FADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGD
2150 2160 2170 2180 2190 2200
2220 2230 2240 2250 2260 2270
pF1KA1 PSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWED
2210 2220 2230 2240 2250 2260
2280 2290 2300 2310 2320 2330
pF1KA1 RPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYE
2270 2280 2290 2300 2310 2320
pF1KA1 TLSDSDD
:::::::
XP_016 TLSDSDD
2330
>>XP_016880905 (OMIM: 600849) PREDICTED: nuclear recepto (2456 aa)
initn: 12308 init1: 12308 opt: 12357 Z-score: 6295.2 bits: 1178.9 E(85289): 0
Smith-Waterman score: 14676; 94.9% identity (95.0% similar) in 2369 aa overlap (1-2250:1-2369)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 ENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 PSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 ADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 PCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREW
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 EVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 YLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 RAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 GSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRAT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 TESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQES
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 RKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 PVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 SPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA1 AMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA1 PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKER
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA1 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850
pF1KA1 TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKE---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKH
1810 1820 1830 1840 1850 1860
pF1KA1 ------------------------------------------------------------
XP_016 EAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAG
1870 1880 1890 1900 1910 1920
1860
pF1KA1 --------------------------------------------------------ISSH
.:::
XP_016 KDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSH
1930 1940 1950 1960 1970 1980
1870 1880 1890 1900 1910 1920
pF1KA1 RYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESP
1990 2000 2010 2020 2030 2040
1930 1940 1950 1960 1970 1980
pF1KA1 SPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNS
2050 2060 2070 2080 2090 2100
1990 2000 2010 2020 2030 2040
pF1KA1 PSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSS
2110 2120 2130 2140 2150 2160
2050 2060 2070 2080 2090 2100
pF1KA1 EPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPM
2170 2180 2190 2200 2210 2220
2110 2120 2130 2140 2150 2160
pF1KA1 VKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLE
2230 2240 2250 2260 2270 2280
2170 2180 2190 2200 2210 2220
pF1KA1 DIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKP
2290 2300 2310 2320 2330 2340
2230 2240 2250 2260 2270 2280
pF1KA1 KLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFP
:::::::::::::::::::::::::::::
XP_016 KLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFP
2350 2360 2370 2380 2390 2400
>--
initn: 616 init1: 616 opt: 616 Z-score: 323.2 bits: 73.8 E(85289): 2.9e-11
Smith-Waterman score: 616; 100.0% identity (100.0% similar) in 87 aa overlap (2251-2337:2370-2456)
2230 2240 2250 2260 2270 2280
pF1KA1 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
::::::::::::::::::::::::::::::
XP_016 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
2340 2350 2360 2370 2380 2390
2290 2300 2310 2320 2330
pF1KA1 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
2400 2410 2420 2430 2440 2450
>>XP_006721667 (OMIM: 600849) PREDICTED: nuclear recepto (2456 aa)
initn: 12308 init1: 12308 opt: 12357 Z-score: 6295.2 bits: 1178.9 E(85289): 0
Smith-Waterman score: 14676; 94.9% identity (95.0% similar) in 2369 aa overlap (1-2250:1-2369)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 ENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 PSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 ADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPMVSCT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 PCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREW
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 EVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTPGT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 YLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGLLV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 RAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEALVK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 GSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEISLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPRAT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 TESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQES
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 RKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEIVP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSARRT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 PVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVVSH
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 SPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLY
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA1 AMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTILV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA1 PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREKER
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA1 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTSVI
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850
pF1KA1 TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKE---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKESKH
1810 1820 1830 1840 1850 1860
pF1KA1 ------------------------------------------------------------
XP_006 EAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAG
1870 1880 1890 1900 1910 1920
1860
pF1KA1 --------------------------------------------------------ISSH
.:::
XP_006 KDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSSSSLSSH
1930 1940 1950 1960 1970 1980
1870 1880 1890 1900 1910 1920
pF1KA1 RYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQESP
1990 2000 2010 2020 2030 2040
1930 1940 1950 1960 1970 1980
pF1KA1 SPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTFQNS
2050 2060 2070 2080 2090 2100
1990 2000 2010 2020 2030 2040
pF1KA1 PSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHVSS
2110 2120 2130 2140 2150 2160
2050 2060 2070 2080 2090 2100
pF1KA1 EPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENTSPM
2170 2180 2190 2200 2210 2220
2110 2120 2130 2140 2150 2160
pF1KA1 VKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLE
2230 2240 2250 2260 2270 2280
2170 2180 2190 2200 2210 2220
pF1KA1 DIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKP
2290 2300 2310 2320 2330 2340
2230 2240 2250 2260 2270 2280
pF1KA1 KLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFP
:::::::::::::::::::::::::::::
XP_006 KLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFP
2350 2360 2370 2380 2390 2400
>--
initn: 616 init1: 616 opt: 616 Z-score: 323.2 bits: 73.8 E(85289): 2.9e-11
Smith-Waterman score: 616; 100.0% identity (100.0% similar) in 87 aa overlap (2251-2337:2370-2456)
2230 2240 2250 2260 2270 2280
pF1KA1 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
::::::::::::::::::::::::::::::
XP_006 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
2340 2350 2360 2370 2380 2390
2290 2300 2310 2320 2330
pF1KA1 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
2400 2410 2420 2430 2440 2450
>>XP_016880904 (OMIM: 600849) PREDICTED: nuclear recepto (2465 aa)
initn: 12892 init1: 8929 opt: 10481 Z-score: 5341.0 bits: 1002.3 E(85289): 0
Smith-Waterman score: 14624; 94.5% identity (94.5% similar) in 2380 aa overlap (1-2251:1-2379)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKT---------NQVMRKKLIL
::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTGVPARRMMKNQVMRKKLIL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQ-IARPSQEEKVEEKEEDKAEKTEKKEE
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_016 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKEEDKAEKTEKKEE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KA1 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KA1 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KA1 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KA1 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KA1 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KA1 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KA1 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA1 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
1810 1820 1830 1840 1850 1860
pF1KA1 DVSKTKE-----------------------------------------------------
:::::::
XP_016 DVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQP
1870 1880 1890 1900 1910 1920
pF1KA1 ------------------------------------------------------------
XP_016 HSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQS
1930 1940 1950 1960 1970 1980
1860 1870 1880 1890 1900 1910
pF1KA1 ------ISSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDSSSSLSSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPL
1990 2000 2010 2020 2030 2040
1920 1930 1940 1950 1960 1970
pF1KA1 HHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQ
2050 2060 2070 2080 2090 2100
1980 1990 2000 2010 2020 2030
pF1KA1 QPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_016 QPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRG-RPG
2110 2120 2130 2140 2150
2040 2050 2060 2070 2080 2090
pF1KA1 KSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSF
2160 2170 2180 2190 2200 2210
2100 2110 2120 2130 2140 2150
pF1KA1 FTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSF
2220 2230 2240 2250 2260 2270
2160 2170 2180 2190 2200 2210
pF1KA1 ADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDP
2280 2290 2300 2310 2320 2330
2220 2230 2240 2250 2260 2270
pF1KA1 SPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDR
::::::::::::::::::::::::::::::::::::::::
XP_016 SPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDR
2340 2350 2360 2370 2380 2390
2280 2290 2300 2310 2320 2330
pF1KA1 PSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYET
XP_016 PSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYET
2400 2410 2420 2430 2440 2450
>--
initn: 611 init1: 611 opt: 611 Z-score: 320.7 bits: 73.4 E(85289): 4e-11
Smith-Waterman score: 611; 100.0% identity (100.0% similar) in 86 aa overlap (2252-2337:2380-2465)
2230 2240 2250 2260 2270 2280
pF1KA1 KLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFP
::::::::::::::::::::::::::::::
XP_016 KLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQFP
2350 2360 2370 2380 2390 2400
2290 2300 2310 2320 2330
pF1KA1 YNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
2410 2420 2430 2440 2450 2460
>>XP_005256931 (OMIM: 600849) PREDICTED: nuclear recepto (2466 aa)
initn: 10824 init1: 8929 opt: 10479 Z-score: 5340.0 bits: 1002.1 E(85289): 0
Smith-Waterman score: 14636; 94.5% identity (94.6% similar) in 2379 aa overlap (1-2250:1-2379)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKT---------NQVMRKKLIL
::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_005 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTGVPARRMMKNQVMRKKLIL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQ-IARPSQEEKVEEKEEDKAEKTEKKEE
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_005 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKEEDKAEKTEKKEE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KA1 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KA1 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KA1 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KA1 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KA1 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KA1 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KA1 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA1 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
1810 1820 1830 1840 1850 1860
pF1KA1 DVSKTKE-----------------------------------------------------
:::::::
XP_005 DVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQP
1870 1880 1890 1900 1910 1920
pF1KA1 ------------------------------------------------------------
XP_005 HSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQS
1930 1940 1950 1960 1970 1980
1860 1870 1880 1890 1900 1910
pF1KA1 ------ISSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDSSSSLSSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPL
1990 2000 2010 2020 2030 2040
1920 1930 1940 1950 1960 1970
pF1KA1 HHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQ
2050 2060 2070 2080 2090 2100
1980 1990 2000 2010 2020 2030
pF1KA1 QPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPG
2110 2120 2130 2140 2150 2160
2040 2050 2060 2070 2080 2090
pF1KA1 KSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSF
2170 2180 2190 2200 2210 2220
2100 2110 2120 2130 2140 2150
pF1KA1 FTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSF
2230 2240 2250 2260 2270 2280
2160 2170 2180 2190 2200 2210
pF1KA1 ADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDP
2290 2300 2310 2320 2330 2340
2220 2230 2240 2250 2260 2270
pF1KA1 SPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDR
:::::::::::::::::::::::::::::::::::::::
XP_005 SPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDR
2350 2360 2370 2380 2390 2400
2280 2290 2300 2310 2320 2330
pF1KA1 PSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYET
XP_005 PSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYET
2410 2420 2430 2440 2450 2460
>--
initn: 616 init1: 616 opt: 616 Z-score: 323.2 bits: 73.8 E(85289): 2.9e-11
Smith-Waterman score: 616; 100.0% identity (100.0% similar) in 87 aa overlap (2251-2337:2380-2466)
2230 2240 2250 2260 2270 2280
pF1KA1 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
::::::::::::::::::::::::::::::
XP_005 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
2350 2360 2370 2380 2390 2400
2290 2300 2310 2320 2330
pF1KA1 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
2410 2420 2430 2440 2450 2460
>>XP_016880906 (OMIM: 600849) PREDICTED: nuclear recepto (2450 aa)
initn: 9450 init1: 7374 opt: 9409 Z-score: 4795.8 bits: 901.4 E(85289): 0
Smith-Waterman score: 14489; 93.9% identity (93.9% similar) in 2379 aa overlap (1-2250:1-2363)
10 20 30 40 50 60
pF1KA1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQLRRRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVSAAVLPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIY
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKT---------NQVMRKKLIL
::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 DENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTGVPARRMMKNQVMRKKLIL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQ-IARPSQEEKVEEKEEDKAEKTEKKEE
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_016 PDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKEEDKAEKTEKKEE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELE
::::::::::::::::: :::::::::::::::::::::::::::
XP_016 DEDIEASNEEENPEDSE----------------VEAVKPSEDSPENATSRGNTEPAVELE
730 740 750 760
780 790 800 810 820 830
pF1KA1 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPP
770 780 790 800 810 820
840 850 860 870 880 890
pF1KA1 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PATKADSVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQ
830 840 850 860 870 880
900 910 920 930 940 950
pF1KA1 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDNDSSATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRA
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KA1 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVIPPMVSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPC
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KA1 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSKSPNREWEVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMG
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KA1 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRS
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
pF1KA1 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNSQPEGLLVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQ
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
pF1KA1 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGIPTEALVKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRS
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KA1 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRTAHEISLKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSG
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
pF1KA1 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIMQGTPRATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEI
1310 1320 1330 1340 1350 1360
1380 1390 1400 1410 1420 1430
pF1KA1 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRQDILTQESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLS
1370 1380 1390 1400 1410 1420
1440 1450 1460 1470 1480 1490
pF1KA1 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGMPPLEIVPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPG
1430 1440 1450 1460 1470 1480
1500 1510 1520 1530 1540 1550
pF1KA1 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYDDTSARRTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSP
1490 1500 1510 1520 1530 1540
1560 1570 1580 1590 1600 1610
pF1KA1 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGVDPVVSHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPT
1550 1560 1570 1580 1590 1600
1620 1630 1640 1650 1660 1670
pF1KA1 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIID
1610 1620 1630 1640 1650 1660
1680 1690 1700 1710 1720 1730
pF1KA1 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTNMPPTILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAER
1670 1680 1690 1700 1710 1720
1740 1750 1760 1770 1780 1790
pF1KA1 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREREREKERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSV
1730 1740 1750 1760 1770 1780
1800 1810 1820 1830 1840 1850
pF1KA1 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQGTNGTSVITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQM
1790 1800 1810 1820 1830 1840
pF1KA1 DVSKTKE-----------------------------------------------------
:::::::
XP_016 DVSKTKESKHEAARLEENLRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQP
1850 1860 1870 1880 1890 1900
pF1KA1 ------------------------------------------------------------
XP_016 HSSVVYSEAGKDKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQS
1910 1920 1930 1940 1950 1960
1860 1870 1880 1890 1900 1910
pF1KA1 ------ISSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDSSSSLSSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPL
1970 1980 1990 2000 2010 2020
1920 1930 1940 1950 1960 1970
pF1KA1 HHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHYRPQQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQ
2030 2040 2050 2060 2070 2080
1980 1990 2000 2010 2020 2030
pF1KA1 QPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPG
2090 2100 2110 2120 2130 2140
2040 2050 2060 2070 2080 2090
pF1KA1 KSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPERSHVSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSF
2150 2160 2170 2180 2190 2200
2100 2110 2120 2130 2140 2150
pF1KA1 FTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSF
2210 2220 2230 2240 2250 2260
2160 2170 2180 2190 2200 2210
pF1KA1 ADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDP
2270 2280 2290 2300 2310 2320
2220 2230 2240 2250 2260 2270
pF1KA1 SPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDR
:::::::::::::::::::::::::::::::::::::::
XP_016 SPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDR
2330 2340 2350 2360 2370 2380
2280 2290 2300 2310 2320 2330
pF1KA1 PSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYET
XP_016 PSSTGSTQFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYET
2390 2400 2410 2420 2430 2440
>--
initn: 616 init1: 616 opt: 616 Z-score: 323.2 bits: 73.8 E(85289): 2.9e-11
Smith-Waterman score: 616; 100.0% identity (100.0% similar) in 87 aa overlap (2251-2337:2364-2450)
2230 2240 2250 2260 2270 2280
pF1KA1 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
::::::::::::::::::::::::::::::
XP_016 PKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGSTQF
2340 2350 2360 2370 2380 2390
2290 2300 2310 2320 2330
pF1KA1 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
2400 2410 2420 2430 2440 2450
>>XP_011522387 (OMIM: 600849) PREDICTED: nuclear recepto (2405 aa)
initn: 14045 init1: 8732 opt: 8775 Z-score: 4473.4 bits: 841.7 E(85289): 0
Smith-Waterman score: 15120; 97.1% identity (97.1% similar) in 2369 aa overlap (37-2337:37-2405)
10 20 30 40 50 60
pF1KA1 PPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLR
::::::::::::::::::::::::::::::
XP_011 PPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQQQQQLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRPSLLSEFHPGSDRPQERRTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSHFQRVSAAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQSMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPLVHPLPEGLRASADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPSKLSKEELIQSMD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 RVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDENRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRSIVQIIYDENRKK
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 AEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKT---------NQVMRKKLILFFKRRN
::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_011 AEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTGVPARRMMKNQVMRKKLILFFKRRN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 HARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 RFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKF
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 INMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLY
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 YYLTKKNENYKALVRRNYGKRRGRNQQ-IARPSQEEKVEEKEEDKAEKTEKKEEEKKDEE
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 YYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 EKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAA
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 SAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 KSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 SNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSEDSPENATSRGNTEPAVELEPTTETA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 PSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKAD
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 SVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDVEVRVPENHASKVEGDNTKERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSS
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 ATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATCSADEDVDGEPERQRMFPMDSKPSLLNPTGSILVSSPLKPNPLDLPQLQHRAAVIPPM
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 VSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSCTPCNIPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSP
970 980 990 1000 1010 1020
1020
pF1KA1 NREWE-------------------------------------------------------
:::::
XP_011 NREWEGKSVAYMPYAEVKRALEQEAQMHNTAARSASPCRLSPREVSKAAPQPDMSAARYS
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070
pF1KA1 ---VLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPPVLQPAPHQVITNLPEGVRLPTTRPTRPPPPLIPSSKTTVASEKPSFIMGGSISQGTP
1090 1100 1110 1120 1130 1140
1080 1090 1100 1110 1120 1130
pF1KA1 GTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTYLTSHNQASYTQETPKPSVGSISLGLPRQQESAKSATLPYIKQEEFSPRSQNSQPEGL
1150 1160 1170 1180 1190 1200
1140 1150 1160 1170 1180 1190
pF1KA1 LVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRAQHEGVVRGTAGAIQEGSITRGTPTSKISVESIPSLRGSITQGTPALPQTGIPTEAL
1210 1220 1230 1240 1250 1260
1200 1210 1220 1230 1240 1250
pF1KA1 VKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKGSISRMPIEDSSPEKGREEAASKGHVIYEGKSGHILSYDNIKNAREGTRSPRTAHEIS
1270 1280 1290 1300 1310 1320
1260 1270 1280 1290 1300 1310
pF1KA1 LKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKRSYESVEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHSDLKERTVLSGSIMQGTPR
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KA1 ATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATTESFEDGLKYPKQIKRESPPIRAFEGAITKGKPYDGITTIKEMGRSIHEIPRQDILTQ
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KA1 ESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRKTPEVVQSTRPIIEGSISQGTPIKFDNNSGQSAIKHNVKSLITGPSKLSRGMPPLEI
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KA1 VPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRSTLHEAPKAQLSPGIYDDTSAR
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KA1 RTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTPVSYQNTMSRGSPMMNRTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGVDPVV
1570 1580 1590 1600 1610 1620
1560 1570 1580 1590 1600 1610
pF1KA1 SHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHSPFDPHHRGSTAGEVYRSHLPTHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQ
1630 1640 1650 1660 1670 1680
1620 1630 1640 1650 1660 1670
pF1KA1 LYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYAMENTRQTILNDYITSQQMQVNLRPDVARGLSPREQPLGLPYPATRGIIDLTNMPPTI
1690 1700 1710 1720 1730 1740
1680 1690 1700 1710 1720 1730
pF1KA1 LVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASMSPGHPTHLAAAASAEREREREREK
1750 1760 1770 1780 1790 1800
1740 1750 1760 1770 1780 1790
pF1KA1 ERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERERERIAAASSDLYLRPGSEQPGRPGSHGYVRSPSPSVRTQETMLQQRPSVFQGTNGTS
1810 1820 1830 1840 1850 1860
1800 1810 1820 1830 1840 1850
pF1KA1 VITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VITPLDPTAQLRIMPLPAGGPSISQGLPASRYNTAADALAALVDAAASAPQMDVSKTKEI
1870 1880 1890 1900 1910 1920
1860 1870 1880 1890 1900 1910
pF1KA1 SSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSHRYETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGPLHHYRPQQ
1930 1940 1950 1960 1970 1980
1920 1930 1940 1950 1960 1970
pF1KA1 ESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQTPQQPPTSTF
1990 2000 2010 2020 2030 2040
1980 1990 2000 2010 2020 2030
pF1KA1 QNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSH
2050 2060 2070 2080 2090 2100
2040 2050 2060 2070 2080 2090
pF1KA1 VSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSEPYEPISPPQVPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKLENT
2110 2120 2130 2140 2150 2160
2100 2110 2120 2130 2140 2150
pF1KA1 SPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNL
2170 2180 2190 2200 2210 2220
2160 2170 2180 2190 2200 2210
pF1KA1 GLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGV
2230 2240 2250 2260 2270 2280
2220 2230 2240 2250 2260 2270
pF1KA1 CKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPGWAWEDRPSSTGST
2290 2300 2310 2320 2330 2340
2280 2290 2300 2310 2320 2330
pF1KA1 QFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFPYNPLTMRMLSSTPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD
2350 2360 2370 2380 2390 2400
2337 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:20:06 2016 done: Wed Nov 2 20:20:09 2016
Total Scan time: 19.920 Total Display time: 2.060
Function used was FASTA [36.3.4 Apr, 2011]