Result of FASTA (omim) for
pFN21AA0985
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0985, 694 aa
1>>>pF1KA0985 694 - 694 aa - 694 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.5430+/-0.000476; mu= -21.4936+/- 0.030
mean_var=603.1288+/-126.001, 0's: 0 Z-trim(124.5): 166 B-trim: 966 in 2/58
Lambda= 0.052224
statistics sampled from 46071 (46269) to 46071 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.542), width: 16
Scan time: 12.060
The best scores are: opt bits E(85289)
XP_011536350 (OMIM: 612159) PREDICTED: rabphilin-3 ( 694) 4813 377.7 8.4e-104
NP_001137326 (OMIM: 612159) rabphilin-3A isoform 1 ( 694) 4813 377.7 8.4e-104
NP_055769 (OMIM: 612159) rabphilin-3A isoform 2 [H ( 690) 4763 373.9 1.1e-102
XP_016874523 (OMIM: 612159) PREDICTED: rabphilin-3 ( 346) 2334 190.7 8.3e-48
XP_016879265 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26
XP_016879266 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26
NP_001268997 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26
NP_003577 (OMIM: 604567) double C2-like domain-con ( 400) 1402 120.5 1.3e-26
NP_001268992 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26
NP_001268991 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26
XP_011544277 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26
XP_016879267 (OMIM: 604567) PREDICTED: double C2-l ( 282) 1200 105.1 3.7e-22
XP_016880716 (OMIM: 604568) PREDICTED: double C2-l ( 340) 891 81.9 4.4e-15
NP_003576 (OMIM: 604568) double C2-like domain-con ( 412) 890 81.9 5.3e-15
XP_011533665 (OMIM: 604568) PREDICTED: double C2-l ( 387) 788 74.2 1e-12
XP_011533666 (OMIM: 604881) PREDICTED: rab effecto ( 321) 750 71.3 6.6e-12
XP_011533667 (OMIM: 604881) PREDICTED: rab effecto ( 321) 750 71.3 6.6e-12
XP_011533668 (OMIM: 604881) PREDICTED: rab effecto ( 321) 750 71.3 6.6e-12
NP_008918 (OMIM: 604881) rab effector Noc2 isoform ( 315) 746 71.0 8e-12
XP_011533669 (OMIM: 604881) PREDICTED: rab effecto ( 315) 746 71.0 8e-12
NP_001177340 (OMIM: 604881) rab effector Noc2 isof ( 315) 746 71.0 8e-12
XP_016880857 (OMIM: 604881) PREDICTED: rab effecto ( 253) 718 68.8 2.9e-11
XP_016880856 (OMIM: 604881) PREDICTED: rab effecto ( 259) 696 67.1 9.4e-11
XP_016880860 (OMIM: 604881) PREDICTED: rab effecto ( 161) 560 56.7 8e-08
XP_011533671 (OMIM: 604881) PREDICTED: rab effecto ( 239) 491 51.7 4e-06
XP_016880858 (OMIM: 604881) PREDICTED: rab effecto ( 239) 491 51.7 4e-06
XP_016880859 (OMIM: 604881) PREDICTED: rab effecto ( 233) 487 51.4 4.8e-06
NP_001177342 (OMIM: 604881) rab effector Noc2 isof ( 286) 466 49.8 1.7e-05
NP_001177341 (OMIM: 604881) rab effector Noc2 isof ( 286) 466 49.8 1.7e-05
XP_011533670 (OMIM: 604881) PREDICTED: rab effecto ( 286) 466 49.8 1.7e-05
XP_016877187 (OMIM: 610950) PREDICTED: synaptotagm ( 339) 381 43.5 0.0016
XP_011535531 (OMIM: 610950) PREDICTED: synaptotagm ( 424) 381 43.6 0.0019
XP_016877185 (OMIM: 610950) PREDICTED: synaptotagm ( 462) 381 43.6 0.002
XP_011535530 (OMIM: 610950) PREDICTED: synaptotagm ( 464) 381 43.6 0.002
XP_011535529 (OMIM: 610950) PREDICTED: synaptotagm ( 505) 381 43.6 0.0022
XP_011535526 (OMIM: 610950) PREDICTED: synaptotagm ( 533) 381 43.7 0.0023
XP_011535527 (OMIM: 610950) PREDICTED: synaptotagm ( 533) 381 43.7 0.0023
XP_011535525 (OMIM: 610950) PREDICTED: synaptotagm ( 535) 381 43.7 0.0023
XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651) 383 43.9 0.0024
XP_016877184 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026
XP_006720335 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026
XP_016877182 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026
NP_114120 (OMIM: 610950) synaptotagmin-16 [Homo sa ( 645) 381 43.7 0.0026
XP_011535521 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026
XP_016877183 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo ( 425) 367 42.5 0.004
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425) 367 42.5 0.004
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443) 367 42.5 0.0041
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478) 367 42.6 0.0043
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484) 367 42.6 0.0044
>>XP_011536350 (OMIM: 612159) PREDICTED: rabphilin-3A is (694 aa)
initn: 4813 init1: 4813 opt: 4813 Z-score: 1984.6 bits: 377.7 E(85289): 8.4e-104
Smith-Waterman score: 4813; 100.0% identity (100.0% similar) in 694 aa overlap (1-694:1-694)
10 20 30 40 50 60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
610 620 630 640 650 660
670 680 690
pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
::::::::::::::::::::::::::::::::::
XP_011 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
670 680 690
>>NP_001137326 (OMIM: 612159) rabphilin-3A isoform 1 [Ho (694 aa)
initn: 4813 init1: 4813 opt: 4813 Z-score: 1984.6 bits: 377.7 E(85289): 8.4e-104
Smith-Waterman score: 4813; 100.0% identity (100.0% similar) in 694 aa overlap (1-694:1-694)
10 20 30 40 50 60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
610 620 630 640 650 660
670 680 690
pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
::::::::::::::::::::::::::::::::::
NP_001 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
670 680 690
>>NP_055769 (OMIM: 612159) rabphilin-3A isoform 2 [Homo (690 aa)
initn: 4621 init1: 4621 opt: 4763 Z-score: 1964.2 bits: 373.9 E(85289): 1.1e-102
Smith-Waterman score: 4763; 99.3% identity (99.4% similar) in 694 aa overlap (1-694:1-690)
10 20 30 40 50 60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
::::::::::::::::::::::: .::::::::::::::::::::::::::::::::
NP_055 MTDTVFSNSSNRWMYPSDRPLQS----KLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
600 610 620 630 640 650
670 680 690
pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
::::::::::::::::::::::::::::::::::
NP_055 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
660 670 680 690
>>XP_016874523 (OMIM: 612159) PREDICTED: rabphilin-3A is (346 aa)
initn: 2334 init1: 2334 opt: 2334 Z-score: 979.3 bits: 190.7 E(85289): 8.3e-48
Smith-Waterman score: 2334; 100.0% identity (100.0% similar) in 346 aa overlap (349-694:1-346)
320 330 340 350 360 370
pF1KA0 PSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEE
::::::::::::::::::::::::::::::
XP_016 MSHPSGPYSQASAAAPQPAAARQPPPPEEE
10 20 30
380 390 400 410 420 430
pF1KA0 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP
40 50 60 70 80 90
440 450 460 470 480 490
pF1KA0 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR
100 110 120 130 140 150
500 510 520 530 540 550
pF1KA0 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL
160 170 180 190 200 210
560 570 580 590 600 610
pF1KA0 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN
220 230 240 250 260 270
620 630 640 650 660 670
pF1KA0 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK
280 290 300 310 320 330
680 690
pF1KA0 IERWHQLQNENHVSSD
::::::::::::::::
XP_016 IERWHQLQNENHVSSD
340
>>XP_016879265 (OMIM: 604567) PREDICTED: double C2-like (400 aa)
initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)
280 290 300 310 320 330
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
::: : : . : :: : :
XP_016 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
10 20 30 40
340 350 360 370 380 390
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
:: :: .: . : ::: ::. : ..:::::.::.:
XP_016 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
50 60 70 80 90
400 410 420 430 440 450
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
:.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
XP_016 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
100 110 120 130 140 150
460 470 480 490 500 510
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.::
XP_016 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
160 170 180 190 200 210
520 530 540 550 560
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.:
XP_016 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
220 230 240 250 260 270
570 580 590 600 610 620
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. :
XP_016 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
280 290 300 310 320 330
630 640 650 660 670 680
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
:: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .:
XP_016 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
340 350 360 370 380 390
690
pF1KA0 HVSSD
XP_016 PPAAGALSSA
400
>>XP_016879266 (OMIM: 604567) PREDICTED: double C2-like (400 aa)
initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)
280 290 300 310 320 330
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
::: : : . : :: : :
XP_016 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
10 20 30 40
340 350 360 370 380 390
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
:: :: .: . : ::: ::. : ..:::::.::.:
XP_016 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
50 60 70 80 90
400 410 420 430 440 450
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
:.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
XP_016 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
100 110 120 130 140 150
460 470 480 490 500 510
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.::
XP_016 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
160 170 180 190 200 210
520 530 540 550 560
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.:
XP_016 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
220 230 240 250 260 270
570 580 590 600 610 620
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. :
XP_016 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
280 290 300 310 320 330
630 640 650 660 670 680
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
:: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .:
XP_016 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
340 350 360 370 380 390
690
pF1KA0 HVSSD
XP_016 PPAAGALSSA
400
>>NP_001268997 (OMIM: 604567) double C2-like domain-cont (400 aa)
initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)
280 290 300 310 320 330
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
::: : : . : :: : :
NP_001 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
10 20 30 40
340 350 360 370 380 390
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
:: :: .: . : ::: ::. : ..:::::.::.:
NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
50 60 70 80 90
400 410 420 430 440 450
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
:.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
100 110 120 130 140 150
460 470 480 490 500 510
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.::
NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
160 170 180 190 200 210
520 530 540 550 560
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.:
NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
220 230 240 250 260 270
570 580 590 600 610 620
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. :
NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
280 290 300 310 320 330
630 640 650 660 670 680
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
:: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .:
NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
340 350 360 370 380 390
690
pF1KA0 HVSSD
NP_001 PPAAGALSSA
400
>>NP_003577 (OMIM: 604567) double C2-like domain-contain (400 aa)
initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)
280 290 300 310 320 330
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
::: : : . : :: : :
NP_003 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
10 20 30 40
340 350 360 370 380 390
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
:: :: .: . : ::: ::. : ..:::::.::.:
NP_003 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
50 60 70 80 90
400 410 420 430 440 450
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
:.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_003 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
100 110 120 130 140 150
460 470 480 490 500 510
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.::
NP_003 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
160 170 180 190 200 210
520 530 540 550 560
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.:
NP_003 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
220 230 240 250 260 270
570 580 590 600 610 620
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. :
NP_003 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
280 290 300 310 320 330
630 640 650 660 670 680
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
:: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .:
NP_003 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
340 350 360 370 380 390
690
pF1KA0 HVSSD
NP_003 PPAAGALSSA
400
>>NP_001268992 (OMIM: 604567) double C2-like domain-cont (400 aa)
initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)
280 290 300 310 320 330
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
::: : : . : :: : :
NP_001 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
10 20 30 40
340 350 360 370 380 390
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
:: :: .: . : ::: ::. : ..:::::.::.:
NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
50 60 70 80 90
400 410 420 430 440 450
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
:.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
100 110 120 130 140 150
460 470 480 490 500 510
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.::
NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
160 170 180 190 200 210
520 530 540 550 560
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.:
NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
220 230 240 250 260 270
570 580 590 600 610 620
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. :
NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
280 290 300 310 320 330
630 640 650 660 670 680
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
:: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .:
NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
340 350 360 370 380 390
690
pF1KA0 HVSSD
NP_001 PPAAGALSSA
400
>>NP_001268991 (OMIM: 604567) double C2-like domain-cont (400 aa)
initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)
280 290 300 310 320 330
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
::: : : . : :: : :
NP_001 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
10 20 30 40
340 350 360 370 380 390
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
:: :: .: . : ::: ::. : ..:::::.::.:
NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
50 60 70 80 90
400 410 420 430 440 450
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
:.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
100 110 120 130 140 150
460 470 480 490 500 510
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.::
NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
160 170 180 190 200 210
520 530 540 550 560
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.:
NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
220 230 240 250 260 270
570 580 590 600 610 620
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. :
NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
280 290 300 310 320 330
630 640 650 660 670 680
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
:: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .:
NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
340 350 360 370 380 390
690
pF1KA0 HVSSD
NP_001 PPAAGALSSA
400
694 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:11:59 2016 done: Wed Nov 2 20:12:00 2016
Total Scan time: 12.060 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]