Result of FASTA (ccds) for
pFN21AA0985
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0985, 694 aa
1>>>pF1KA0985 694 - 694 aa - 694 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.6768+/-0.00119; mu= -15.9591+/- 0.071
mean_var=538.7992+/-108.171, 0's: 0 Z-trim(116.8): 56 B-trim: 0 in 0/53
Lambda= 0.055254
statistics sampled from 17403 (17456) to 17403 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.536), width: 16
Scan time: 4.570
The best scores are: opt bits E(32554)
CCDS44979.1 RPH3A gene_id:22895|Hs108|chr12 ( 694) 4813 398.4 1.8e-110
CCDS31904.1 RPH3A gene_id:22895|Hs108|chr12 ( 690) 4763 394.4 2.9e-109
CCDS10666.1 DOC2A gene_id:8448|Hs108|chr16 ( 400) 1402 126.3 8.5e-29
CCDS73934.1 DOC2B gene_id:8447|Hs108|chr17 ( 412) 890 85.5 1.7e-16
CCDS10994.1 RPH3AL gene_id:9501|Hs108|chr17 ( 315) 746 73.9 3.9e-13
>>CCDS44979.1 RPH3A gene_id:22895|Hs108|chr12 (694 aa)
initn: 4813 init1: 4813 opt: 4813 Z-score: 2096.7 bits: 398.4 E(32554): 1.8e-110
Smith-Waterman score: 4813; 100.0% identity (100.0% similar) in 694 aa overlap (1-694:1-694)
10 20 30 40 50 60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
610 620 630 640 650 660
670 680 690
pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
::::::::::::::::::::::::::::::::::
CCDS44 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
670 680 690
>>CCDS31904.1 RPH3A gene_id:22895|Hs108|chr12 (690 aa)
initn: 4621 init1: 4621 opt: 4763 Z-score: 2075.2 bits: 394.4 E(32554): 2.9e-109
Smith-Waterman score: 4763; 99.3% identity (99.4% similar) in 694 aa overlap (1-694:1-690)
10 20 30 40 50 60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
::::::::::::::::::::::: .::::::::::::::::::::::::::::::::
CCDS31 MTDTVFSNSSNRWMYPSDRPLQS----KLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
600 610 620 630 640 650
670 680 690
pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
::::::::::::::::::::::::::::::::::
CCDS31 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
660 670 680 690
>>CCDS10666.1 DOC2A gene_id:8448|Hs108|chr16 (400 aa)
initn: 1398 init1: 708 opt: 1402 Z-score: 630.4 bits: 126.3 E(32554): 8.5e-29
Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389)
280 290 300 310 320 330
pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
::: : : . : :: : :
CCDS10 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
10 20 30 40
340 350 360 370 380 390
pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
:: :: .: . : ::: ::. : ..:::::.::.:
CCDS10 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
50 60 70 80 90
400 410 420 430 440 450
pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
:.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
CCDS10 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
100 110 120 130 140 150
460 470 480 490 500 510
pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.::
CCDS10 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
160 170 180 190 200 210
520 530 540 550 560
pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.:
CCDS10 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
220 230 240 250 260 270
570 580 590 600 610 620
pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. :
CCDS10 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
280 290 300 310 320 330
630 640 650 660 670 680
pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
:: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .:
CCDS10 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
340 350 360 370 380 390
690
pF1KA0 HVSSD
CCDS10 PPAAGALSSA
400
>>CCDS73934.1 DOC2B gene_id:8447|Hs108|chr17 (412 aa)
initn: 1582 init1: 824 opt: 890 Z-score: 409.7 bits: 85.5 E(32554): 1.7e-16
Smith-Waterman score: 1617; 62.0% identity (79.0% similar) in 400 aa overlap (297-688:24-404)
270 280 290 300 310 320
pF1KA0 LRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPG--T
:: :: . :: . :. : : : .
CCDS73 MTLRRRGEKATISIQEHMAIDVCPGPIRPIKQISDYFP-RFPRGLPPDAGPRA
10 20 30 40 50
330 340 350 360 370
pF1KA0 TAPPREERTGGVGGY----PAVGAREDR--MSHPSGPYSQASAAAPQPAAARQPPPPEEE
.::: .:.: :. ::::: ... : :... . .: :. :: : : :.
CCDS73 AAPPDAPARPAVAGAGRRSPSDGAREDDEDVDQLFGAYGSSPGPSPGPSPARPPAKPPED
60 70 80 90 100 110
380 390 400 410 420 430
pF1KA0 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP
: .:..:.::. :.::.:.:::::::.:..:.::: ::::::::: ::::::::::::::
CCDS73 EPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLP
120 130 140 150 160 170
440 450 460 470 480 490
pF1KA0 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR
::::.::::::::::: :: :::::.:.::::::: :::::::::::::: :::::::::
CCDS73 GASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETR
180 190 200 210 220 230
500 510 520 530 540 550
pF1KA0 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL
:::::::. :.:.::::. .:. .. :.. ..::::.::.::
CCDS73 VPLKKLKPNHTKTFSICLEKQLPVDKT-------------EDK-----SLEERGRILISL
240 250 260 270
560 570 580 590 600 610
pF1KA0 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN
::.:. ::.:::.::.:::::::::::::.:: .:.::. ::.:::: .::::::::::
CCDS73 KYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFN
280 290 300 310 320 330
620 630 640 650 660 670
pF1KA0 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK
::: :.:::.:::::::...:::::::::::.::: ::: :::::::::..:::::::.
CCDS73 EEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKR
340 350 360 370 380 390
680 690
pF1KA0 IERWHQLQNENHVSSD
::::: : .:
CCDS73 IERWHTLTSELPGAVLSD
400 410
>>CCDS10994.1 RPH3AL gene_id:9501|Hs108|chr17 (315 aa)
initn: 651 init1: 387 opt: 746 Z-score: 349.2 bits: 73.9 E(32554): 3.9e-13
Smith-Waterman score: 772; 39.2% identity (66.5% similar) in 337 aa overlap (1-324:1-312)
10 20 30 40 50 60
pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
:.::.:......:. :.:: : . .::.::::: : ..::....:. : : : .
CCDS10 MADTIFGSGNDQWVCPNDRQLAL--RAKLQTGWSVHTY-QTEKQRRKQHLSPAEVEAILQ
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
:: :::... .::.::::::.:::.::.:: :.:...:.:::: ::.:::. : :.::.:
CCDS10 VIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRK
60 70 80 90 100 110
130 140 150 160 170
pF1KA0 NVCTKCGVETN-NRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQ-
.::::::.:.. .. . .:::::: :::::::::::::.::.:: .:: : . :.
CCDS10 KVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KA0 QPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASE
.:. :. : . :. .. .: . . :: .. : : . .. :
CCDS10 RPL--PTEPAEREPRSSETSRIYTWA-----RGRVVSSDSDSDSDLSSSSL--------E
180 190 200 210 220
240 250 260 270 280
pF1KA0 ARMSSSS-RDSES---WDHSGGAGDSSR-----SPAGLRRANSVQAS-RPAPGSVQSPAP
:. :.. :: .. : .:::. .. : :. : .: :: . . ::.. :.
CCDS10 DRLPSTGVRDRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGG
230 240 250 260 270 280
290 300 310 320 330 340
pF1KA0 PQPGQPG-TPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGARED
:.:: .: . :: .::. ..::. :..
CCDS10 PRPGLTRRAPVKDTPGRAPAA-------DAAPAGPSSCLG
290 300 310
350 360 370 380 390 400
pF1KA0 RMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNS
694 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:11:58 2016 done: Wed Nov 2 20:11:58 2016
Total Scan time: 4.570 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]