Result of FASTA (omim) for
pFN21AA0358
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0358, 1581 aa
1>>>pF1KA0358 1581 - 1581 aa - 1581 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0708+/-0.000418; mu= 10.4035+/- 0.026
mean_var=133.3839+/-28.363, 0's: 0 Z-trim(115.9): 161 B-trim: 1309 in 2/54
Lambda= 0.111051
statistics sampled from 26460 (26632) to 26460 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.312), width: 16
Scan time: 13.330
The best scores are: opt bits E(85289)
NP_569831 (OMIM: 603584) MAP kinase-activating dea (1581) 10463 1688.9 0
XP_005253257 (OMIM: 603584) PREDICTED: MAP kinase- (1580) 10446 1686.2 0
XP_016873977 (OMIM: 603584) PREDICTED: MAP kinase- (1577) 10425 1682.8 0
XP_016873978 (OMIM: 603584) PREDICTED: MAP kinase- (1577) 10425 1682.8 0
NP_003673 (OMIM: 603584) MAP kinase-activating dea (1647) 10416 1681.4 0
XP_005253246 (OMIM: 603584) PREDICTED: MAP kinase- (1647) 10416 1681.4 0
XP_016873967 (OMIM: 603584) PREDICTED: MAP kinase- (1643) 10378 1675.3 0
XP_016873979 (OMIM: 603584) PREDICTED: MAP kinase- (1563) 7477 1210.5 0
XP_016873980 (OMIM: 603584) PREDICTED: MAP kinase- (1562) 7475 1210.2 0
XP_016873981 (OMIM: 603584) PREDICTED: MAP kinase- (1559) 7472 1209.7 0
XP_016873968 (OMIM: 603584) PREDICTED: MAP kinase- (1625) 7472 1209.7 0
XP_005253253 (OMIM: 603584) PREDICTED: MAP kinase- (1608) 7447 1205.7 0
NP_569829 (OMIM: 603584) MAP kinase-activating dea (1608) 7447 1205.7 0
XP_016873969 (OMIM: 603584) PREDICTED: MAP kinase- (1607) 7442 1204.9 0
XP_016873971 (OMIM: 603584) PREDICTED: MAP kinase- (1604) 7439 1204.4 0
XP_016873989 (OMIM: 603584) PREDICTED: MAP kinase- (1521) 5885 955.4 0
XP_016873986 (OMIM: 603584) PREDICTED: MAP kinase- (1539) 5885 955.4 0
XP_016873985 (OMIM: 603584) PREDICTED: MAP kinase- (1539) 5885 955.4 0
XP_016873984 (OMIM: 603584) PREDICTED: MAP kinase- (1542) 5885 955.4 0
XP_016873983 (OMIM: 603584) PREDICTED: MAP kinase- (1543) 5885 955.4 0
XP_016873982 (OMIM: 603584) PREDICTED: MAP kinase- (1557) 5885 955.4 0
XP_016873974 (OMIM: 603584) PREDICTED: MAP kinase- (1584) 5885 955.4 0
XP_016873973 (OMIM: 603584) PREDICTED: MAP kinase- (1584) 5885 955.4 0
NP_569832 (OMIM: 603584) MAP kinase-activating dea (1587) 5885 955.4 0
NP_569826 (OMIM: 603584) MAP kinase-activating dea (1588) 5885 955.4 0
XP_005253256 (OMIM: 603584) PREDICTED: MAP kinase- (1588) 5885 955.4 0
XP_016873970 (OMIM: 603584) PREDICTED: MAP kinase- (1605) 5885 955.4 0
XP_005253262 (OMIM: 603584) PREDICTED: MAP kinase- (1479) 5079 826.3 0
NP_569830 (OMIM: 603584) MAP kinase-activating dea (1479) 5079 826.3 0
XP_016873999 (OMIM: 603584) PREDICTED: MAP kinase- (1496) 5079 826.3 0
XP_016873998 (OMIM: 603584) PREDICTED: MAP kinase- (1499) 5079 826.3 0
XP_016873997 (OMIM: 603584) PREDICTED: MAP kinase- (1500) 5079 826.3 0
XP_016873996 (OMIM: 603584) PREDICTED: MAP kinase- (1514) 5079 826.3 0
XP_016873995 (OMIM: 603584) PREDICTED: MAP kinase- (1516) 5079 826.3 0
XP_016873994 (OMIM: 603584) PREDICTED: MAP kinase- (1516) 5079 826.3 0
XP_016873993 (OMIM: 603584) PREDICTED: MAP kinase- (1519) 5079 826.3 0
XP_016873992 (OMIM: 603584) PREDICTED: MAP kinase- (1519) 5079 826.3 0
XP_016873990 (OMIM: 603584) PREDICTED: MAP kinase- (1520) 5079 826.3 0
XP_016873991 (OMIM: 603584) PREDICTED: MAP kinase- (1520) 5079 826.3 0
XP_016873988 (OMIM: 603584) PREDICTED: MAP kinase- (1534) 5079 826.3 0
XP_016873987 (OMIM: 603584) PREDICTED: MAP kinase- (1534) 5079 826.3 0
NP_001129416 (OMIM: 603584) MAP kinase-activating (1541) 5079 826.3 0
XP_005253261 (OMIM: 603584) PREDICTED: MAP kinase- (1541) 5079 826.3 0
NP_001129415 (OMIM: 603584) MAP kinase-activating (1544) 5079 826.3 0
XP_005253260 (OMIM: 603584) PREDICTED: MAP kinase- (1545) 5079 826.3 0
NP_569828 (OMIM: 603584) MAP kinase-activating dea (1545) 5079 826.3 0
XP_005253258 (OMIM: 603584) PREDICTED: MAP kinase- (1565) 5079 826.3 0
NP_569827 (OMIM: 603584) MAP kinase-activating dea (1565) 5079 826.3 0
XP_016873976 (OMIM: 603584) PREDICTED: MAP kinase- (1580) 5079 826.3 0
XP_016873975 (OMIM: 603584) PREDICTED: MAP kinase- (1582) 5079 826.3 0
>>NP_569831 (OMIM: 603584) MAP kinase-activating death d (1581 aa)
initn: 10463 init1: 10463 opt: 10463 Z-score: 9058.1 bits: 1688.9 E(85289): 0
Smith-Waterman score: 10463; 100.0% identity (100.0% similar) in 1581 aa overlap (1-1581:1-1581)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1510 1520 1530 1540 1550 1560
1570 1580
pF1KA0 VTLEGINLKFMHNQFLKLKKW
:::::::::::::::::::::
NP_569 VTLEGINLKFMHNQFLKLKKW
1570 1580
>>XP_005253257 (OMIM: 603584) PREDICTED: MAP kinase-acti (1580 aa)
initn: 7922 init1: 7922 opt: 10446 Z-score: 9043.4 bits: 1686.2 E(85289): 0
Smith-Waterman score: 10446; 99.9% identity (99.9% similar) in 1581 aa overlap (1-1581:1-1580)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -SNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1500 1510 1520 1530 1540 1550
1570 1580
pF1KA0 VTLEGINLKFMHNQFLKLKKW
:::::::::::::::::::::
XP_005 VTLEGINLKFMHNQFLKLKKW
1560 1570 1580
>>XP_016873977 (OMIM: 603584) PREDICTED: MAP kinase-acti (1577 aa)
initn: 7914 init1: 7914 opt: 10425 Z-score: 9025.2 bits: 1682.8 E(85289): 0
Smith-Waterman score: 10425; 99.7% identity (99.7% similar) in 1581 aa overlap (1-1581:1-1577)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVS--
1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --NSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1500 1510 1520 1530 1540 1550
1570 1580
pF1KA0 VTLEGINLKFMHNQFLKLKKW
:::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
1560 1570
>>XP_016873978 (OMIM: 603584) PREDICTED: MAP kinase-acti (1577 aa)
initn: 7914 init1: 7914 opt: 10425 Z-score: 9025.2 bits: 1682.8 E(85289): 0
Smith-Waterman score: 10425; 99.7% identity (99.7% similar) in 1581 aa overlap (1-1581:1-1577)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVS--
1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --NSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1500 1510 1520 1530 1540 1550
1570 1580
pF1KA0 VTLEGINLKFMHNQFLKLKKW
:::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
1560 1570
>>NP_003673 (OMIM: 603584) MAP kinase-activating death d (1647 aa)
initn: 10412 init1: 10412 opt: 10416 Z-score: 9017.1 bits: 1681.4 E(85289): 0
Smith-Waterman score: 10416; 99.8% identity (99.9% similar) in 1579 aa overlap (1-1578:1-1579)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1510 1520 1530 1540 1550 1560
1570 1580
pF1KA0 VTLEGINLKFMHNQ-FLKLKKW
:::::::::::::: :..:
NP_003 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS
1570 1580 1590 1600 1610 1620
>>XP_005253246 (OMIM: 603584) PREDICTED: MAP kinase-acti (1647 aa)
initn: 10412 init1: 10412 opt: 10416 Z-score: 9017.1 bits: 1681.4 E(85289): 0
Smith-Waterman score: 10416; 99.8% identity (99.9% similar) in 1579 aa overlap (1-1578:1-1579)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1510 1520 1530 1540 1550 1560
1570 1580
pF1KA0 VTLEGINLKFMHNQ-FLKLKKW
:::::::::::::: :..:
XP_005 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS
1570 1580 1590 1600 1610 1620
>>XP_016873967 (OMIM: 603584) PREDICTED: MAP kinase-acti (1643 aa)
initn: 7914 init1: 7914 opt: 10378 Z-score: 8984.2 bits: 1675.3 E(85289): 0
Smith-Waterman score: 10378; 99.6% identity (99.7% similar) in 1579 aa overlap (1-1578:1-1575)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEV---
1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -SNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1500 1510 1520 1530 1540 1550
1570 1580
pF1KA0 VTLEGINLKFMHNQ-FLKLKKW
:::::::::::::: :..:
XP_016 VTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYS
1560 1570 1580 1590 1600 1610
>>XP_016873979 (OMIM: 603584) PREDICTED: MAP kinase-acti (1563 aa)
initn: 10321 init1: 7420 opt: 7477 Z-score: 6472.7 bits: 1210.5 E(85289): 0
Smith-Waterman score: 10286; 98.8% identity (98.8% similar) in 1581 aa overlap (1-1581:1-1563)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
:::::::::::::::::::::::::::::::::::::::: :
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIG------------------P
1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1490 1500 1510 1520 1530 1540
1570 1580
pF1KA0 VTLEGINLKFMHNQFLKLKKW
:::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
1550 1560
>>XP_016873980 (OMIM: 603584) PREDICTED: MAP kinase-acti (1562 aa)
initn: 9958 init1: 7420 opt: 7475 Z-score: 6471.0 bits: 1210.2 E(85289): 0
Smith-Waterman score: 10269; 98.7% identity (98.7% similar) in 1581 aa overlap (1-1581:1-1562)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
:::::::::::::::::::::::::::::::::::::::: :
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIG------------------P
1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -SNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1490 1500 1510 1520 1530 1540
1570 1580
pF1KA0 VTLEGINLKFMHNQFLKLKKW
:::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
1550 1560
>>XP_016873981 (OMIM: 603584) PREDICTED: MAP kinase-acti (1559 aa)
initn: 9952 init1: 7420 opt: 7472 Z-score: 6468.4 bits: 1209.7 E(85289): 0
Smith-Waterman score: 10248; 98.5% identity (98.5% similar) in 1581 aa overlap (1-1581:1-1559)
10 20 30 40 50 60
pF1KA0 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKEKGEGGAGSRGKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHATCASEEGGTESSESGSSLQPLSADSTPDVNQSPRGKRRAKAGSRSRNSTLTSLCVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEKSSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLELKKHLKQALASMSLNTQPILNLEKFHEGQEIPLLLGRPSNDLQSTPSTEFNPLIYGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEALSVPPERDSDSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASSSPSTVIHGANSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEDEDEQGESYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTST
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGEGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEKQRP
:::::::::::::::::::::::::::::::::::::::: :
XP_016 KAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIG------------------P
1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVS--
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KA0 VSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --NSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLK
1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KA0 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSIKEKLAGSPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQ
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KA0 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLIS
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KA0 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKK
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KA0 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRR
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KA0 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQ
1480 1490 1500 1510 1520 1530
1570 1580
pF1KA0 VTLEGINLKFMHNQFLKLKKW
:::::::::::::::::::::
XP_016 VTLEGINLKFMHNQFLKLKKW
1540 1550
1581 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:42:34 2016 done: Wed Nov 2 18:42:36 2016
Total Scan time: 13.330 Total Display time: 1.180
Function used was FASTA [36.3.4 Apr, 2011]