Result of FASTA (omim) for
pFN21AA0164
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0164, 920 aa
1>>>pF1KA0164 920 - 920 aa - 920 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.9180+/-0.000465; mu= -2.2424+/- 0.029
mean_var=409.2757+/-84.930, 0's: 0 Z-trim(121.5): 227 B-trim: 1333 in 2/59
Lambda= 0.063397
statistics sampled from 37833 (38088) to 37833 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.447), width: 16
Scan time: 16.350
The best scores are: opt bits E(85289)
NP_055554 (OMIM: 612588) bcl-2-associated transcri ( 920) 6138 576.5 2.1e-163
NP_001287967 (OMIM: 612588) bcl-2-associated trans ( 918) 6114 574.3 9.6e-163
XP_005267294 (OMIM: 612588) PREDICTED: bcl-2-assoc ( 871) 5305 500.3 1.7e-140
NP_001070908 (OMIM: 612588) bcl-2-associated trans ( 869) 5281 498.1 8e-140
XP_016867018 (OMIM: 612588) PREDICTED: bcl-2-assoc ( 745) 2743 265.9 5.4e-70
NP_001070909 (OMIM: 612588) bcl-2-associated trans ( 747) 2743 265.9 5.4e-70
XP_016867019 (OMIM: 612588) PREDICTED: bcl-2-assoc ( 698) 2290 224.4 1.5e-57
XP_016867020 (OMIM: 612588) PREDICTED: bcl-2-assoc ( 696) 2266 222.2 7e-57
XP_016867021 (OMIM: 612588) PREDICTED: bcl-2-assoc ( 309) 2048 201.9 4e-51
NP_001308402 (OMIM: 603809) thyroid hormone recept ( 954) 1256 130.0 5.6e-29
NP_001308400 (OMIM: 603809) thyroid hormone recept ( 955) 1247 129.1 9.9e-29
NP_005110 (OMIM: 603809) thyroid hormone receptor- ( 955) 1247 129.1 9.9e-29
XP_005271428 (OMIM: 603809) PREDICTED: thyroid hor ( 568) 744 82.9 4.9e-15
XP_005255283 (OMIM: 606032) PREDICTED: serine/argi (2751) 379 50.2 0.00016
NP_057417 (OMIM: 606032) serine/arginine repetitiv (2752) 379 50.2 0.00016
XP_016866202 (OMIM: 616653) PREDICTED: arginine/se ( 719) 317 44.0 0.0033
XP_016866201 (OMIM: 616653) PREDICTED: arginine/se ( 719) 317 44.0 0.0033
XP_016866199 (OMIM: 616653) PREDICTED: arginine/se ( 796) 317 44.0 0.0035
XP_016866200 (OMIM: 616653) PREDICTED: arginine/se ( 796) 317 44.0 0.0035
XP_011540253 (OMIM: 601940) PREDICTED: serine/argi ( 464) 311 43.2 0.0036
NP_001309341 (OMIM: 616653) arginine/serine-rich p ( 814) 317 44.0 0.0036
NP_001309342 (OMIM: 616653) arginine/serine-rich p ( 814) 317 44.0 0.0036
XP_005266969 (OMIM: 616653) PREDICTED: arginine/se ( 814) 317 44.0 0.0036
NP_001309339 (OMIM: 616653) arginine/serine-rich p ( 814) 317 44.0 0.0036
NP_115285 (OMIM: 603269) serine/arginine-rich spli ( 282) 302 42.2 0.0045
XP_016872631 (OMIM: 603269) PREDICTED: serine/argi ( 282) 302 42.2 0.0045
NP_005617 (OMIM: 601940) serine/arginine-rich spli ( 494) 303 42.5 0.0062
NP_001309344 (OMIM: 616653) arginine/serine-rich p ( 787) 304 42.8 0.008
NP_001309343 (OMIM: 616653) arginine/serine-rich p ( 787) 304 42.8 0.008
NP_001309334 (OMIM: 616653) arginine/serine-rich p ( 805) 304 42.8 0.0081
NP_001309337 (OMIM: 616653) arginine/serine-rich p ( 805) 304 42.8 0.0081
NP_001309335 (OMIM: 616653) arginine/serine-rich p ( 805) 304 42.8 0.0081
NP_056306 (OMIM: 616653) arginine/serine-rich prot ( 805) 304 42.8 0.0081
NP_116259 (OMIM: 616653) arginine/serine-rich prot ( 805) 304 42.8 0.0081
XP_016864544 (OMIM: 609268) PREDICTED: splicing re ( 503) 297 42.0 0.0091
>>NP_055554 (OMIM: 612588) bcl-2-associated transcriptio (920 aa)
initn: 6138 init1: 6138 opt: 6138 Z-score: 3054.6 bits: 576.5 E(85289): 2.1e-163
Smith-Waterman score: 6138; 100.0% identity (100.0% similar) in 920 aa overlap (1-920:1-920)
10 20 30 40 50 60
pF1KA0 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
850 860 870 880 890 900
910 920
pF1KA0 EEETMENNEEKKDRRKEEKE
::::::::::::::::::::
NP_055 EEETMENNEEKKDRRKEEKE
910 920
>>NP_001287967 (OMIM: 612588) bcl-2-associated transcrip (918 aa)
initn: 5993 init1: 5993 opt: 6114 Z-score: 3042.7 bits: 574.3 E(85289): 9.6e-163
Smith-Waterman score: 6114; 99.8% identity (99.8% similar) in 920 aa overlap (1-920:1-918)
10 20 30 40 50 60
pF1KA0 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
:::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA0 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
840 850 860 870 880 890
910 920
pF1KA0 EEETMENNEEKKDRRKEEKE
::::::::::::::::::::
NP_001 EEETMENNEEKKDRRKEEKE
900 910
>>XP_005267294 (OMIM: 612588) PREDICTED: bcl-2-associate (871 aa)
initn: 5283 init1: 5283 opt: 5305 Z-score: 2643.1 bits: 500.3 E(85289): 1.7e-140
Smith-Waterman score: 5688; 94.7% identity (94.7% similar) in 920 aa overlap (1-920:1-871)
10 20 30 40 50 60
pF1KA0 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
:::::::::::::::::::
XP_005 HEMKEYSGFAGVSRPRGTF-----------------------------------------
790
850 860 870 880 890 900
pF1KA0 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 --------HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
800 810 820 830 840 850
910 920
pF1KA0 EEETMENNEEKKDRRKEEKE
::::::::::::::::::::
XP_005 EEETMENNEEKKDRRKEEKE
860 870
>>NP_001070908 (OMIM: 612588) bcl-2-associated transcrip (869 aa)
initn: 5138 init1: 5138 opt: 5281 Z-score: 2631.3 bits: 498.1 E(85289): 8e-140
Smith-Waterman score: 5664; 94.5% identity (94.5% similar) in 920 aa overlap (1-920:1-869)
10 20 30 40 50 60
pF1KA0 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
:::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
:::::::::::::::::::
NP_001 HEMKEYSGFAGVSRPRGTF-----------------------------------------
780 790
850 860 870 880 890 900
pF1KA0 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
800 810 820 830 840
910 920
pF1KA0 EEETMENNEEKKDRRKEEKE
::::::::::::::::::::
NP_001 EEETMENNEEKKDRRKEEKE
850 860
>>XP_016867018 (OMIM: 612588) PREDICTED: bcl-2-associate (745 aa)
initn: 4860 init1: 2729 opt: 2743 Z-score: 1377.6 bits: 265.9 E(85289): 5.4e-70
Smith-Waterman score: 4639; 81.0% identity (81.0% similar) in 920 aa overlap (1-920:1-745)
10 20 30 40 50 60
pF1KA0 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
:::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
::::::::::::::::::::::::::::::::::::::
XP_016 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK----------------------
300 310 320 330
370 380 390 400 410 420
pF1KA0 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
XP_016 ------------------------------------------------------------
430 440 450 460 470 480
pF1KA0 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
XP_016 ------------------------------------------------------------
490 500 510 520 530 540
pF1KA0 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
:::::::::::::::::::::::::::::
XP_016 -------------------------------SPPLHKNLDAREKSTFREESPLRIKMIAS
340 350 360
550 560 570 580 590 600
pF1KA0 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
370 380 390 400 410 420
610 620 630 640 650 660
pF1KA0 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
430 440 450 460 470 480
670 680 690 700 710 720
pF1KA0 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
490 500 510 520 530 540
730 740 750 760 770 780
pF1KA0 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
550 560 570 580 590 600
790 800 810 820 830 840
pF1KA0 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
610 620 630 640 650 660
850 860 870 880 890 900
pF1KA0 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
670 680 690 700 710 720
910 920
pF1KA0 EEETMENNEEKKDRRKEEKE
::::::::::::::::::::
XP_016 EEETMENNEEKKDRRKEEKE
730 740
>>NP_001070909 (OMIM: 612588) bcl-2-associated transcrip (747 aa)
initn: 5005 init1: 2729 opt: 2743 Z-score: 1377.6 bits: 265.9 E(85289): 5.4e-70
Smith-Waterman score: 4663; 81.2% identity (81.2% similar) in 920 aa overlap (1-920:1-747)
10 20 30 40 50 60
pF1KA0 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
::::::::::::::::::::::::::::::::::::::
NP_001 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK----------------------
310 320 330
370 380 390 400 410 420
pF1KA0 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
NP_001 ------------------------------------------------------------
430 440 450 460 470 480
pF1KA0 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
NP_001 ------------------------------------------------------------
490 500 510 520 530 540
pF1KA0 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
:::::::::::::::::::::::::::::
NP_001 -------------------------------SPPLHKNLDAREKSTFREESPLRIKMIAS
340 350 360
550 560 570 580 590 600
pF1KA0 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
370 380 390 400 410 420
610 620 630 640 650 660
pF1KA0 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
430 440 450 460 470 480
670 680 690 700 710 720
pF1KA0 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
490 500 510 520 530 540
730 740 750 760 770 780
pF1KA0 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
550 560 570 580 590 600
790 800 810 820 830 840
pF1KA0 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
610 620 630 640 650 660
850 860 870 880 890 900
pF1KA0 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
670 680 690 700 710 720
910 920
pF1KA0 EEETMENNEEKKDRRKEEKE
::::::::::::::::::::
NP_001 EEETMENNEEKKDRRKEEKE
730 740
>>XP_016867019 (OMIM: 612588) PREDICTED: bcl-2-associate (698 aa)
initn: 4150 init1: 2290 opt: 2290 Z-score: 1154.0 bits: 224.4 E(85289): 1.5e-57
Smith-Waterman score: 4213; 75.9% identity (75.9% similar) in 920 aa overlap (1-920:1-698)
10 20 30 40 50 60
pF1KA0 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
::::::::::::::::::::::::::::::::::::::
XP_016 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK----------------------
310 320 330
370 380 390 400 410 420
pF1KA0 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
XP_016 ------------------------------------------------------------
430 440 450 460 470 480
pF1KA0 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
XP_016 ------------------------------------------------------------
490 500 510 520 530 540
pF1KA0 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
:::::::::::::::::::::::::::::
XP_016 -------------------------------SPPLHKNLDAREKSTFREESPLRIKMIAS
340 350 360
550 560 570 580 590 600
pF1KA0 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
370 380 390 400 410 420
610 620 630 640 650 660
pF1KA0 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
430 440 450 460 470 480
670 680 690 700 710 720
pF1KA0 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
490 500 510 520 530 540
730 740 750 760 770 780
pF1KA0 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
550 560 570 580 590 600
790 800 810 820 830 840
pF1KA0 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
:::::::::::::::::::
XP_016 HEMKEYSGFAGVSRPRGTF-----------------------------------------
610 620
850 860 870 880 890 900
pF1KA0 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
630 640 650 660 670
910 920
pF1KA0 EEETMENNEEKKDRRKEEKE
::::::::::::::::::::
XP_016 EEETMENNEEKKDRRKEEKE
680 690
>>XP_016867020 (OMIM: 612588) PREDICTED: bcl-2-associate (696 aa)
initn: 4005 init1: 2145 opt: 2266 Z-score: 1142.2 bits: 222.2 E(85289): 7e-57
Smith-Waterman score: 4189; 75.7% identity (75.7% similar) in 920 aa overlap (1-920:1-696)
10 20 30 40 50 60
pF1KA0 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
:::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
::::::::::::::::::::::::::::::::::::::
XP_016 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK----------------------
300 310 320 330
370 380 390 400 410 420
pF1KA0 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
XP_016 ------------------------------------------------------------
430 440 450 460 470 480
pF1KA0 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
XP_016 ------------------------------------------------------------
490 500 510 520 530 540
pF1KA0 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
:::::::::::::::::::::::::::::
XP_016 -------------------------------SPPLHKNLDAREKSTFREESPLRIKMIAS
340 350 360
550 560 570 580 590 600
pF1KA0 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
370 380 390 400 410 420
610 620 630 640 650 660
pF1KA0 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
430 440 450 460 470 480
670 680 690 700 710 720
pF1KA0 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
490 500 510 520 530 540
730 740 750 760 770 780
pF1KA0 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
550 560 570 580 590 600
790 800 810 820 830 840
pF1KA0 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
:::::::::::::::::::
XP_016 HEMKEYSGFAGVSRPRGTF-----------------------------------------
610 620
850 860 870 880 890 900
pF1KA0 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
630 640 650 660 670
910 920
pF1KA0 EEETMENNEEKKDRRKEEKE
::::::::::::::::::::
XP_016 EEETMENNEEKKDRRKEEKE
680 690
>>XP_016867021 (OMIM: 612588) PREDICTED: bcl-2-associate (309 aa)
initn: 2048 init1: 2048 opt: 2048 Z-score: 1038.8 bits: 201.9 E(85289): 4e-51
Smith-Waterman score: 2048; 100.0% identity (100.0% similar) in 303 aa overlap (618-920:7-309)
590 600 610 620 630 640
pF1KA0 IFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQK
::::::::::::::::::::::::::::::
XP_016 MCWILGEQYFKSAAMTLNERFTSYQKATEEHSTRQK
10 20 30
650 660 670 680 690 700
pF1KA0 SPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE
40 50 60 70 80 90
710 720 730 740 750 760
pF1KA0 RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEK
100 110 120 130 140 150
770 780 790 800 810 820
pF1KA0 ESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQ
160 170 180 190 200 210
830 840 850 860 870 880
pF1KA0 KRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW
220 230 240 250 260 270
890 900 910 920
pF1KA0 THDKYQGDGIVEDEEETMENNEEKKDRRKEEKE
:::::::::::::::::::::::::::::::::
XP_016 THDKYQGDGIVEDEEETMENNEEKKDRRKEEKE
280 290 300
>>NP_001308402 (OMIM: 603809) thyroid hormone receptor-a (954 aa)
initn: 1132 init1: 358 opt: 1256 Z-score: 641.2 bits: 130.0 E(85289): 5.6e-29
Smith-Waterman score: 1938; 41.0% identity (66.1% similar) in 970 aa overlap (2-913:10-948)
10 20 30 40
pF1KA0 MGRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRYSSRSRSRTYSRSRSR
: .:::.: :::.::: :.::::::: .:::.: :::::::.:: ...:
NP_001 MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 DRMYSRDYR-RDYR-NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGY---RPVW-NRRHSR
.: . : :. ::.: .:::.:::: .:::.::.: : .:.:::: : : : :..
NP_001 ERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWG--QYNRGGYGNYRSNWQNYRQAY
70 80 90 100 110
110 120 130 140 150 160
pF1KA0 SPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGS
:::::::::::::::: : ::::.:: : .:: :: ::::::::: .:. :::...
NP_001 SPRRGRSRSRSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KA0 QEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN
.::.... ...:.. . ....: ..:: :.. .:.: .: :: . .
NP_001 KEKKSSSKDSRPSQAAG-DNQGDEAKEQTFSGGTSQD----TKASESSKP-WPDATYGTG
180 190 200 210 220 230
230 240 250 260 270
pF1KA0 SPRSPHSPSPIATPPSQSSSCSDAPMLSTV---HSAKNTPSQHSHSIQHSPERSGSGSVG
: . : .. : . : .:. :.: .: . .: . : . :: ..
NP_001 SASRASAVSELS--PRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGS-TLP
240 250 260 270 280
280 290 300 310 320 330
pF1KA0 NGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTG--KF
.:.. : .... . : . ::.: ..: : : : : .. .:.: .: .
NP_001 SGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSP--PSTG--STYGSSQKEESAASGGAAY
290 300 310 320 330 340
340 350 360 370 380 390
pF1KA0 LKRFTDEESRVFLLDRGNTR---DKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGK
::. .:.. :. . . ::: ::::: . : ..:. .. : :. : ...
NP_001 TKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKS----DSFAPKTDSE
350 360 370 380 390 400
400 410 420 430 440
pF1KA0 QKFNDSEGDDTEETED-----YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKG
. : :.. . .: . .:.: . :: :. : . ... .. :. ::: . .
NP_001 KPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKV-IGA
410 420 430 440 450
450 460 470 480 490
pF1KA0 NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEE-DKNSERITVKKETQS---------
:.... :::. : . : : :. :... :: ...: ::: ..
NP_001 NKNQE---EEKSGKWE--GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRG
460 470 480 490 500 510
500 510 520 530 540 550
pF1KA0 --PEQ---VKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKM
::. : . : . . ::: .:. ..:.: . . : : : ... .:...:
NP_001 FVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRM
520 530 540 550 560 570
560 570 580 590 600 610
pF1KA0 APVPLDDSNRPASL-TKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIV
.: ::..: ...: : :::: ::::::::::.::. :...: :: : ::::
NP_001 DSFD-EDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIV
580 590 600 610 620 630
620 630 640 650 660
pF1KA0 SLVHHVKEQYFKSAAMTLNERFTSY-QKATEEHSTR-QKSPEIHRRIDISPSTLRKHTRL
..::::::..: :..:::.::::.: ...::..... .:::::::::::::::.:::
NP_001 TIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLA
640 650 660 670 680 690
670 680 690 700 710 720
pF1KA0 AGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK--ERSKERGDSK---GSRESSGSRKQ
: . .: . :.. : . : .::: ::.::.: ::. .:: :. ::.:: ::..
NP_001 HDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRER
700 710 720 730 740 750
730 740 750 760 770
pF1KA0 EKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPS-SPSSREEKESKKEREEEF----K
.. : : .:. : ..::.: .:.:::::::.. : : ...: : .:::: :
NP_001 -SAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDK
760 770 780 790 800 810
780 790 800 810 820 830
pF1KA0 THHEMKEYSGFA--GVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWD
.. :.. : . : .: :::::: :::: .:: ..:.:. ::::. :::: .:::::
NP_001 SRLGTKDFVGPSERGGGRARGTFFRARGRGWGRGNYSGNNN--NNSNNDFQKRNREEEWD
820 830 840 850 860
840 850 860 870 880 890
pF1KA0 PEYTPKSKKYFLHDDRD-DGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGD
::::::::::.:::::. .: : :..::::::.: :::::: :.::..::::.:::..:.
NP_001 PEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGE
870 880 890 900 910 920
900 910 920
pF1KA0 -GIVEDEEETMENNEEKKDRRKEEKE
: .::.: :: ::: .
NP_001 EGEIEDDESGTENREEKDNIQPTTE
930 940 950
920 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:19:56 2016 done: Wed Nov 2 18:19:59 2016
Total Scan time: 16.350 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]