Result of FASTA (omim) for
pFN21ASDA1769
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1769, 2080 aa
1>>>pF1KSDA1769 2080 - 2080 aa - 2080 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6673+/-0.000393; mu= 24.2617+/- 0.025
mean_var=93.0303+/-18.962, 0's: 0 Z-trim(114.2): 74 B-trim: 282 in 2/50
Lambda= 0.132973
statistics sampled from 23911 (23986) to 23911 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.281), width: 16
Scan time: 16.120
The best scores are: opt bits E(85289)
NP_208384 (OMIM: 611265) helicase with zinc finger (2080) 14093 2715.3 0
NP_001032412 (OMIM: 611265) helicase with zinc fin (2649) 14050 2707.2 0
XP_016880967 (OMIM: 606699) PREDICTED: probable he (1551) 770 159.4 2.9e-37
XP_006722279 (OMIM: 606699) PREDICTED: probable he (1578) 770 159.4 3e-37
XP_016880966 (OMIM: 606699) PREDICTED: probable he (1707) 770 159.4 3.2e-37
XP_006722278 (OMIM: 606699) PREDICTED: probable he (1735) 770 159.4 3.2e-37
NP_055692 (OMIM: 606699) probable helicase with zi (1942) 770 159.4 3.5e-37
NP_001317376 (OMIM: 606699) probable helicase with (1943) 770 159.4 3.5e-37
XP_005257945 (OMIM: 606699) PREDICTED: probable he (1969) 770 159.4 3.5e-37
XP_006722277 (OMIM: 606699) PREDICTED: probable he (1970) 770 159.4 3.5e-37
XP_011523846 (OMIM: 606699) PREDICTED: probable he (1970) 770 159.4 3.5e-37
NP_001310867 (OMIM: 614183) DIS3-like exonuclease ( 920) 433 94.5 5.7e-18
NP_001310875 (OMIM: 614183) DIS3-like exonuclease ( 920) 433 94.5 5.7e-18
NP_001310870 (OMIM: 614183) DIS3-like exonuclease ( 920) 433 94.5 5.7e-18
NP_001310868 (OMIM: 614183) DIS3-like exonuclease ( 920) 433 94.5 5.7e-18
NP_001310866 (OMIM: 614183) DIS3-like exonuclease ( 928) 433 94.5 5.8e-18
NP_001310874 (OMIM: 614183) DIS3-like exonuclease ( 971) 433 94.5 6e-18
NP_588616 (OMIM: 614183) DIS3-like exonuclease 1 i ( 971) 433 94.5 6e-18
NP_001310865 (OMIM: 614183) DIS3-like exonuclease ( 971) 433 94.5 6e-18
NP_001310877 (OMIM: 614183) DIS3-like exonuclease ( 994) 433 94.6 6.1e-18
NP_001310873 (OMIM: 614183) DIS3-like exonuclease (1037) 433 94.6 6.3e-18
NP_001137160 (OMIM: 614183) DIS3-like exonuclease (1054) 433 94.6 6.4e-18
NP_001310872 (OMIM: 614183) DIS3-like exonuclease ( 684) 425 92.9 1.3e-17
NP_001310869 (OMIM: 614183) DIS3-like exonuclease ( 684) 425 92.9 1.3e-17
XP_005254203 (OMIM: 614183) PREDICTED: DIS3-like e ( 848) 412 90.5 8.8e-17
NP_001309278 (OMIM: 607533) exosome complex exonuc ( 796) 323 73.4 1.2e-11
NP_001309277 (OMIM: 607533) exosome complex exonuc ( 835) 323 73.4 1.2e-11
NP_001121698 (OMIM: 607533) exosome complex exonuc ( 928) 323 73.4 1.3e-11
NP_055768 (OMIM: 607533) exosome complex exonuclea ( 958) 323 73.4 1.3e-11
NP_001244210 (OMIM: 267000,614184) DIS3-like exonu ( 603) 302 69.2 1.5e-10
NP_689596 (OMIM: 267000,614184) DIS3-like exonucle ( 885) 302 69.4 2e-10
NP_002171 (OMIM: 600502,604320,616155) DNA-binding ( 993) 277 64.6 6.2e-09
XP_016873159 (OMIM: 600502,604320,616155) PREDICTE ( 656) 274 63.9 6.8e-09
XP_005274031 (OMIM: 600502,604320,616155) PREDICTE ( 656) 274 63.9 6.8e-09
XP_016873158 (OMIM: 600502,604320,616155) PREDICTE ( 656) 274 63.9 6.8e-09
XP_005270926 (OMIM: 610742) PREDICTED: putative he ( 947) 275 64.2 7.8e-09
NP_001273001 (OMIM: 610742) putative helicase MOV- ( 947) 275 64.2 7.8e-09
XP_005270927 (OMIM: 610742) PREDICTED: putative he ( 947) 275 64.2 7.8e-09
XP_016856807 (OMIM: 610742) PREDICTED: putative he ( 947) 275 64.2 7.8e-09
NP_066014 (OMIM: 610742) putative helicase MOV-10 (1003) 275 64.2 8.1e-09
NP_001123551 (OMIM: 610742) putative helicase MOV- (1003) 275 64.2 8.1e-09
NP_001308253 (OMIM: 610742) putative helicase MOV- (1003) 275 64.2 8.1e-09
XP_016873160 (OMIM: 600502,604320,616155) PREDICTE ( 546) 245 58.3 2.8e-07
NP_001157578 (OMIM: 605794) RNA helicase Mov10l1 i ( 338) 239 57.0 4.3e-07
XP_005261980 (OMIM: 605794) PREDICTED: RNA helicas (1191) 239 57.4 1.1e-06
NP_061868 (OMIM: 605794) RNA helicase Mov10l1 isof (1211) 239 57.4 1.1e-06
NP_001157577 (OMIM: 605794) RNA helicase Mov10l1 i (1165) 219 53.6 1.6e-05
XP_011537719 (OMIM: 601810,615156,615807) PREDICTE ( 700) 198 49.3 0.00017
XP_016871288 (OMIM: 601810,615156,615807) PREDICTE ( 836) 198 49.4 0.0002
NP_001073918 (OMIM: 601810,615156,615807) DNA repl (1060) 198 49.5 0.00024
>>NP_208384 (OMIM: 611265) helicase with zinc finger dom (2080 aa)
initn: 14093 init1: 14093 opt: 14093 Z-score: 14601.2 bits: 2715.3 E(85289): 0
Smith-Waterman score: 14093; 99.8% identity (100.0% similar) in 2080 aa overlap (1-2080:1-2080)
10 20 30 40 50 60
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FRPPTRAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 FRPPTRAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 LVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGNPDRDMSMASWLNLAEIAQVVE
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_208 VSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 KVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 VVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 SFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AVVTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 AVVTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD ESTEAEDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 ESTEAEDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD YENLPPAALRKLLRAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAG
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_208 YENLPPAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD DEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 DEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ELKDPSQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 ELKDPSQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD ASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 ASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD ACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 ACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD SLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 SLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 GAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 IQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD SPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 SPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD CARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 CARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD FSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 FSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD PVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 PVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD QLLELVELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 QLLELVELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD SLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 SLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFC
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD ALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 ALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD IRLEGLLAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTEDWDQERRADRQEAPRRVHLF
:::::: ::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_208 IRLEGLPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLF
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD VHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 VHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD LCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 LCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVF
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD WFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 WFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD EASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 EASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGE
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KSD LFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 LFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KSD TLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 TLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KSD GICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 GICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNEN
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KSD SKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 SKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSIT
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KSD KSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 KSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIG
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080
pF1KSD DHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS
::::::::::::::::::::::::::::::::::::::::
NP_208 DHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS
2050 2060 2070 2080
>>NP_001032412 (OMIM: 611265) helicase with zinc finger (2649 aa)
initn: 14050 init1: 14050 opt: 14050 Z-score: 14555.2 bits: 2707.2 E(85289): 0
Smith-Waterman score: 14050; 99.7% identity (99.9% similar) in 2075 aa overlap (6-2080:575-2649)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
. ::::::::::::::::::::::::::::
NP_001 PFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATPLRVM
550 560 570 580 590 600
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVPVGFFSHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVPVGFFSHI
610 620 630 640 650 660
100 110 120 130 140 150
pF1KSD LIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCY
670 680 690 700 710 720
160 170 180 190 200 210
pF1KSD QQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCH
730 740 750 760 770 780
220 230 240 250 260 270
pF1KSD VAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQ
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQ
790 800 810 820 830 840
280 290 300 310 320 330
pF1KSD ELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTR
850 860 870 880 890 900
340 350 360 370 380 390
pF1KSD AQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPR
910 920 930 940 950 960
400 410 420 430 440 450
pF1KSD GTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTEAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTEAAAA
970 980 990 1000 1010 1020
460 470 480 490 500 510
pF1KSD PAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAILRELLDESQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAILRELLDESQK
1030 1040 1050 1060 1070 1080
520 530 540 550 560 570
pF1KSD VMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLRAEPERYRHCSFVPETFERASA
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_001 VMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLHAEPERYRHCSFVPETFERASA
1090 1100 1110 1120 1130 1140
580 590 600 610 620 630
pF1KSD IPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAF
1150 1160 1170 1180 1190 1200
640 650 660 670 680 690
pF1KSD VCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQRVGLERLTAEARHSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQRVGLERLTAEARHSRL
1210 1220 1230 1240 1250 1260
700 710 720 730 740 750
pF1KSD FWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYH
1270 1280 1290 1300 1310 1320
760 770 780 790 800 810
pF1KSD TELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGV
1330 1340 1350 1360 1370 1380
820 830 840 850 860 870
pF1KSD LDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLR
1390 1400 1410 1420 1430 1440
880 890 900 910 920 930
pF1KSD FAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHRLRSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHRLRSD
1450 1460 1470 1480 1490 1500
940 950 960 970 980 990
pF1KSD CFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLK
1510 1520 1530 1540 1550 1560
1000 1010 1020 1030 1040 1050
pF1KSD ALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTT
1570 1580 1590 1600 1610 1620
1060 1070 1080 1090 1100 1110
pF1KSD DDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQ
1630 1640 1650 1660 1670 1680
1120 1130 1140 1150 1160 1170
pF1KSD RQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFV
1690 1700 1710 1720 1730 1740
1180 1190 1200 1210 1220 1230
pF1KSD VDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQG
1750 1760 1770 1780 1790 1800
1240 1250 1260 1270 1280 1290
pF1KSD SSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQRRELVQVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQRRELVQVQR
1810 1820 1830 1840 1850 1860
1300 1310 1320 1330 1340 1350
pF1KSD SHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFS
1870 1880 1890 1900 1910 1920
1360 1370 1380 1390 1400 1410
pF1KSD GRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQ
1930 1940 1950 1960 1970 1980
1420 1430 1440 1450 1460 1470
pF1KSD GAFRLEAAFLEENCADINFSCCYLCIRLEGLLAPTASPRPGPSSLGPGLNVDPGTYTWVA
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 GAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLGPGLNVDPGTYTWVA
1990 2000 2010 2020 2030 2040
1480 1490 1500 1510 1520 1530
pF1KSD HGQTEDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKE
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKE
2050 2060 2070 2080 2090 2100
1540 1550 1560 1570 1580 1590
pF1KSD EAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREA
2110 2120 2130 2140 2150 2160
1600 1610 1620 1630 1640 1650
pF1KSD LEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNK
2170 2180 2190 2200 2210 2220
1660 1670 1680 1690 1700 1710
pF1KSD SVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLH
2230 2240 2250 2260 2270 2280
1720 1730 1740 1750 1760 1770
pF1KSD HRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCA
2290 2300 2310 2320 2330 2340
1780 1790 1800 1810 1820 1830
pF1KSD ASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNL
2350 2360 2370 2380 2390 2400
1840 1850 1860 1870 1880 1890
pF1KSD GLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKES
2410 2420 2430 2440 2450 2460
1900 1910 1920 1930 1940 1950
pF1KSD CPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPY
2470 2480 2490 2500 2510 2520
1960 1970 1980 1990 2000 2010
pF1KSD NAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF
2530 2540 2550 2560 2570 2580
2020 2030 2040 2050 2060 2070
pF1KSD LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRR
2590 2600 2610 2620 2630 2640
2080
pF1KSD PTMPS
:::::
NP_001 PTMPS
>>XP_016880967 (OMIM: 606699) PREDICTED: probable helica (1551 aa)
initn: 906 init1: 229 opt: 770 Z-score: 789.9 bits: 159.4 E(85289): 2.9e-37
Smith-Waterman score: 931; 41.0% identity (66.3% similar) in 398 aa overlap (6-383:308-695)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
: ::::.::..:.: .: .:.:.: ::::.
XP_016 YGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
280 290 300 310 320 330
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
XP_016 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
340 350 360 370 380 390
100 110 120 130 140 150
pF1KSD SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
XP_016 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
400 410 420 430 440 450
160 170 180 190 200 210
pF1KSD FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
XP_016 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
460 470 480 490 500
220 230 240 250 260 270
pF1KSD MFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA-QV
: . :. .. . ... : ::. .:::.:.: :: :: .. : ::. : ::
XP_016 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
510 520 530 540 550 560
280 290 300 310 320
pF1KSD SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
.: :::.. :..:.: . :.::::. :::: :::. .: .
XP_016 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
570 580 590 600 610 620
330 340 350 360 370
pF1KSD ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
XP_016 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
630 640 650 660 670 680
380 390 400 410 420 430
pF1KSD GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
:...::..
XP_016 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
690 700 710 720 730 740
>>XP_006722279 (OMIM: 606699) PREDICTED: probable helica (1578 aa)
initn: 906 init1: 229 opt: 770 Z-score: 789.8 bits: 159.4 E(85289): 3e-37
Smith-Waterman score: 931; 41.0% identity (66.3% similar) in 398 aa overlap (6-383:335-722)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
: ::::.::..:.: .: .:.:.: ::::.
XP_006 YGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
310 320 330 340 350 360
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
XP_006 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
370 380 390 400 410 420
100 110 120 130 140 150
pF1KSD SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
XP_006 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
430 440 450 460 470 480
160 170 180 190 200 210
pF1KSD FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
XP_006 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
490 500 510 520 530
220 230 240 250 260 270
pF1KSD MFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA-QV
: . :. .. . ... : ::. .:::.:.: :: :: .. : ::. : ::
XP_006 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
540 550 560 570 580 590
280 290 300 310 320
pF1KSD SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
.: :::.. :..:.: . :.::::. :::: :::. .: .
XP_006 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
600 610 620 630 640 650
330 340 350 360 370
pF1KSD ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
XP_006 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
660 670 680 690 700 710
380 390 400 410 420 430
pF1KSD GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
:...::..
XP_006 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
720 730 740 750 760 770
>>XP_016880966 (OMIM: 606699) PREDICTED: probable helica (1707 aa)
initn: 906 init1: 229 opt: 770 Z-score: 789.3 bits: 159.4 E(85289): 3.2e-37
Smith-Waterman score: 931; 41.0% identity (66.3% similar) in 398 aa overlap (6-383:464-851)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
: ::::.::..:.: .: .:.:.: ::::.
XP_016 PYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
440 450 460 470 480 490
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
XP_016 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
500 510 520 530 540 550
100 110 120 130 140 150
pF1KSD SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
XP_016 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
560 570 580 590 600 610
160 170 180 190 200 210
pF1KSD FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
XP_016 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
620 630 640 650 660
220 230 240 250 260 270
pF1KSD MFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA-QV
: . :. .. . ... : ::. .:::.:.: :: :: .. : ::. : ::
XP_016 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
670 680 690 700 710 720
280 290 300 310 320
pF1KSD SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
.: :::.. :..:.: . :.::::. :::: :::. .: .
XP_016 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
730 740 750 760 770 780
330 340 350 360 370
pF1KSD ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
XP_016 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
790 800 810 820 830 840
380 390 400 410 420 430
pF1KSD GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
:...::..
XP_016 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
850 860 870 880 890 900
>>XP_006722278 (OMIM: 606699) PREDICTED: probable helica (1735 aa)
initn: 906 init1: 229 opt: 770 Z-score: 789.2 bits: 159.4 E(85289): 3.2e-37
Smith-Waterman score: 931; 41.0% identity (66.3% similar) in 398 aa overlap (6-383:492-879)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
: ::::.::..:.: .: .:.:.: ::::.
XP_006 YGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
470 480 490 500 510 520
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
XP_006 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
530 540 550 560 570 580
100 110 120 130 140 150
pF1KSD SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
XP_006 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
590 600 610 620 630 640
160 170 180 190 200 210
pF1KSD FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
XP_006 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
650 660 670 680 690
220 230 240 250 260 270
pF1KSD MFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA-QV
: . :. .. . ... : ::. .:::.:.: :: :: .. : ::. : ::
XP_006 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
700 710 720 730 740 750
280 290 300 310 320
pF1KSD SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
.: :::.. :..:.: . :.::::. :::: :::. .: .
XP_006 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
760 770 780 790 800 810
330 340 350 360 370
pF1KSD ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
XP_006 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
820 830 840 850 860 870
380 390 400 410 420 430
pF1KSD GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
:...::..
XP_006 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
880 890 900 910 920 930
>>NP_055692 (OMIM: 606699) probable helicase with zinc f (1942 aa)
initn: 906 init1: 229 opt: 770 Z-score: 788.6 bits: 159.4 E(85289): 3.5e-37
Smith-Waterman score: 931; 41.0% identity (66.3% similar) in 398 aa overlap (6-383:699-1086)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
: ::::.::..:.: .: .:.:.: ::::.
NP_055 PYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
670 680 690 700 710 720
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
NP_055 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
730 740 750 760 770 780
100 110 120 130 140 150
pF1KSD SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
NP_055 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
790 800 810 820 830 840
160 170 180 190 200 210
pF1KSD FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
NP_055 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
850 860 870 880 890 900
220 230 240 250 260 270
pF1KSD MFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA-QV
: . :. .. . ... : ::. .:::.:.: :: :: .. : ::. : ::
NP_055 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
910 920 930 940 950 960
280 290 300 310 320
pF1KSD SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
.: :::.. :..:.: . :.::::. :::: :::. .: .
NP_055 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
970 980 990 1000 1010 1020
330 340 350 360 370
pF1KSD ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
NP_055 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
1030 1040 1050 1060 1070
380 390 400 410 420 430
pF1KSD GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
:...::..
NP_055 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
1080 1090 1100 1110 1120 1130
>>NP_001317376 (OMIM: 606699) probable helicase with zin (1943 aa)
initn: 906 init1: 229 opt: 770 Z-score: 788.6 bits: 159.4 E(85289): 3.5e-37
Smith-Waterman score: 931; 41.0% identity (66.3% similar) in 398 aa overlap (6-383:700-1087)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
: ::::.::..:.: .: .:.:.: ::::.
NP_001 YGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
670 680 690 700 710 720
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
NP_001 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
730 740 750 760 770 780
100 110 120 130 140 150
pF1KSD SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
NP_001 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
790 800 810 820 830 840
160 170 180 190 200 210
pF1KSD FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
NP_001 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
850 860 870 880 890 900
220 230 240 250 260 270
pF1KSD MFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA-QV
: . :. .. . ... : ::. .:::.:.: :: :: .. : ::. : ::
NP_001 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
910 920 930 940 950 960
280 290 300 310 320
pF1KSD SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
.: :::.. :..:.: . :.::::. :::: :::. .: .
NP_001 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
970 980 990 1000 1010 1020
330 340 350 360 370
pF1KSD ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
NP_001 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
1030 1040 1050 1060 1070
380 390 400 410 420 430
pF1KSD GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
:...::..
NP_001 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
1080 1090 1100 1110 1120 1130
>>XP_005257945 (OMIM: 606699) PREDICTED: probable helica (1969 aa)
initn: 906 init1: 229 opt: 770 Z-score: 788.5 bits: 159.4 E(85289): 3.5e-37
Smith-Waterman score: 931; 41.0% identity (66.3% similar) in 398 aa overlap (6-383:726-1113)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
: ::::.::..:.: .: .:.:.: ::::.
XP_005 PYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
700 710 720 730 740 750
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
XP_005 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
760 770 780 790 800 810
100 110 120 130 140 150
pF1KSD SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
XP_005 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
820 830 840 850 860 870
160 170 180 190 200 210
pF1KSD FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
XP_005 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
880 890 900 910 920
220 230 240 250 260 270
pF1KSD MFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA-QV
: . :. .. . ... : ::. .:::.:.: :: :: .. : ::. : ::
XP_005 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
930 940 950 960 970 980
280 290 300 310 320
pF1KSD SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
.: :::.. :..:.: . :.::::. :::: :::. .: .
XP_005 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
990 1000 1010 1020 1030 1040
330 340 350 360 370
pF1KSD ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
XP_005 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
1050 1060 1070 1080 1090 1100
380 390 400 410 420 430
pF1KSD GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
:...::..
XP_005 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
1110 1120 1130 1140 1150 1160
>>XP_006722277 (OMIM: 606699) PREDICTED: probable helica (1970 aa)
initn: 906 init1: 229 opt: 770 Z-score: 788.5 bits: 159.4 E(85289): 3.5e-37
Smith-Waterman score: 931; 41.0% identity (66.3% similar) in 398 aa overlap (6-383:727-1114)
10 20 30
pF1KSD MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
: ::::.::..:.: .: .:.:.: ::::.
XP_006 YGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
700 710 720 730 740 750
40 50 60 70 80 90
pF1KSD YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
XP_006 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
760 770 780 790 800 810
100 110 120 130 140 150
pF1KSD SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
XP_006 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
820 830 840 850 860 870
160 170 180 190 200 210
pF1KSD FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
XP_006 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
880 890 900 910 920
220 230 240 250 260 270
pF1KSD MFCHVAGNPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA-QV
: . :. .. . ... : ::. .:::.:.: :: :: .. : ::. : ::
XP_006 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
930 940 950 960 970 980
280 290 300 310 320
pF1KSD SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
.: :::.. :..:.: . :.::::. :::: :::. .: .
XP_006 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
990 1000 1010 1020 1030 1040
330 340 350 360 370
pF1KSD ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
XP_006 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
1050 1060 1070 1080 1090 1100
380 390 400 410 420 430
pF1KSD GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
:...::..
XP_006 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
1110 1120 1130 1140 1150 1160
2080 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:10:16 2016 done: Thu Nov 3 19:10:19 2016
Total Scan time: 16.120 Total Display time: 0.640
Function used was FASTA [36.3.4 Apr, 2011]