Result of FASTA (omim) for
pFN21AE9686
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9686, 533 aa
1>>>pF1KE9686 533 - 533 aa - 533 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7495+/-0.000344; mu= 11.9495+/- 0.022
mean_var=104.7395+/-21.361, 0's: 0 Z-trim(116.7): 34 B-trim: 247 in 1/51
Lambda= 0.125320
statistics sampled from 27979 (28011) to 27979 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.328), width: 16
Scan time: 7.380
The best scores are: opt bits E(85289)
NP_001139568 (OMIM: 613534,614817) fanconi-associa ( 533) 3455 635.4 1.3e-181
NP_001139566 (OMIM: 613534,614817) fanconi-associa ( 533) 3455 635.4 1.3e-181
NP_001139567 (OMIM: 613534,614817) fanconi-associa ( 533) 3455 635.4 1.3e-181
XP_011519674 (OMIM: 613534,614817) PREDICTED: fanc ( 609) 3397 624.9 2.1e-178
XP_005254289 (OMIM: 613534,614817) PREDICTED: fanc (1017) 3397 625.0 3.2e-178
XP_005254292 (OMIM: 613534,614817) PREDICTED: fanc (1017) 3397 625.0 3.2e-178
XP_005254291 (OMIM: 613534,614817) PREDICTED: fanc (1017) 3397 625.0 3.2e-178
NP_055782 (OMIM: 613534,614817) fanconi-associated (1017) 3397 625.0 3.2e-178
XP_011519673 (OMIM: 613534,614817) PREDICTED: fanc ( 622) 728 142.4 3.9e-33
XP_011519672 (OMIM: 613534,614817) PREDICTED: fanc ( 623) 723 141.5 7.3e-33
>>NP_001139568 (OMIM: 613534,614817) fanconi-associated (533 aa)
initn: 3415 init1: 3415 opt: 3455 Z-score: 3381.5 bits: 635.4 E(85289): 1.3e-181
Smith-Waterman score: 3455; 99.6% identity (99.6% similar) in 533 aa overlap (1-533:2-533)
10 20 30 40 50
pF1KE9 MSEGKPPDKKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMSEGKPPDKK-RPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRESKIMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_001 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
480 490 500 510 520 530
>>NP_001139566 (OMIM: 613534,614817) fanconi-associated (533 aa)
initn: 3415 init1: 3415 opt: 3455 Z-score: 3381.5 bits: 635.4 E(85289): 1.3e-181
Smith-Waterman score: 3455; 99.6% identity (99.6% similar) in 533 aa overlap (1-533:2-533)
10 20 30 40 50
pF1KE9 MSEGKPPDKKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMSEGKPPDKK-RPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRESKIMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_001 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
480 490 500 510 520 530
>>NP_001139567 (OMIM: 613534,614817) fanconi-associated (533 aa)
initn: 3415 init1: 3415 opt: 3455 Z-score: 3381.5 bits: 635.4 E(85289): 1.3e-181
Smith-Waterman score: 3455; 99.6% identity (99.6% similar) in 533 aa overlap (1-533:2-533)
10 20 30 40 50
pF1KE9 MSEGKPPDKKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMSEGKPPDKK-RPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRESKIMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_001 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
480 490 500 510 520 530
>>XP_011519674 (OMIM: 613534,614817) PREDICTED: fanconi- (609 aa)
initn: 3357 init1: 3357 opt: 3397 Z-score: 3324.0 bits: 624.9 E(85289): 2.1e-178
Smith-Waterman score: 3397; 99.6% identity (99.6% similar) in 526 aa overlap (1-526:2-526)
10 20 30 40 50
pF1KE9 MSEGKPPDKKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMSEGKPPDKK-RPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRESKIMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_011 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICK
480 490 500 510 520 530
XP_011 GPRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDR
540 550 560 570 580 590
>>XP_005254289 (OMIM: 613534,614817) PREDICTED: fanconi- (1017 aa)
initn: 3357 init1: 3357 opt: 3397 Z-score: 3320.6 bits: 625.0 E(85289): 3.2e-178
Smith-Waterman score: 3397; 99.6% identity (99.6% similar) in 526 aa overlap (1-526:2-526)
10 20 30 40 50
pF1KE9 MSEGKPPDKKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMSEGKPPDKK-RPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRESKIMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICK
480 490 500 510 520 530
XP_005 GPRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDR
540 550 560 570 580 590
>>XP_005254292 (OMIM: 613534,614817) PREDICTED: fanconi- (1017 aa)
initn: 3357 init1: 3357 opt: 3397 Z-score: 3320.6 bits: 625.0 E(85289): 3.2e-178
Smith-Waterman score: 3397; 99.6% identity (99.6% similar) in 526 aa overlap (1-526:2-526)
10 20 30 40 50
pF1KE9 MSEGKPPDKKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMSEGKPPDKK-RPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRESKIMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICK
480 490 500 510 520 530
XP_005 GPRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDR
540 550 560 570 580 590
>>XP_005254291 (OMIM: 613534,614817) PREDICTED: fanconi- (1017 aa)
initn: 3357 init1: 3357 opt: 3397 Z-score: 3320.6 bits: 625.0 E(85289): 3.2e-178
Smith-Waterman score: 3397; 99.6% identity (99.6% similar) in 526 aa overlap (1-526:2-526)
10 20 30 40 50
pF1KE9 MSEGKPPDKKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMSEGKPPDKK-RPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRESKIMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICK
480 490 500 510 520 530
XP_005 GPRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDR
540 550 560 570 580 590
>>NP_055782 (OMIM: 613534,614817) fanconi-associated nuc (1017 aa)
initn: 3357 init1: 3357 opt: 3397 Z-score: 3320.6 bits: 625.0 E(85289): 3.2e-178
Smith-Waterman score: 3397; 99.6% identity (99.6% similar) in 526 aa overlap (1-526:2-526)
10 20 30 40 50
pF1KE9 MSEGKPPDKKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MMSEGKPPDKK-RPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRH
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LDEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EVKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRESKIMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_055 SPQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ESQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREAC
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HCEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RLFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
:::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICK
480 490 500 510 520 530
NP_055 GPRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDR
540 550 560 570 580 590
>>XP_011519673 (OMIM: 613534,614817) PREDICTED: fanconi- (622 aa)
initn: 728 init1: 728 opt: 728 Z-score: 715.9 bits: 142.4 E(85289): 3.9e-33
Smith-Waterman score: 728; 99.1% identity (100.0% similar) in 116 aa overlap (411-526:16-131)
390 400 410 420 430 440
pF1KE9 VVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIA
.:::::::::::::::::::::::::::::
XP_011 MPEVLGSQGWLQASSAATGQKLYVRLFQRKLSWIKMTKLEYEEIA
10 20 30 40
450 460 470 480 490 500
pF1KE9 LDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAF
50 60 70 80 90 100
510 520 530
pF1KE9 LKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
::::::::::::::::::::::::::
XP_011 LKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMED
110 120 130 140 150 160
>>XP_011519672 (OMIM: 613534,614817) PREDICTED: fanconi- (623 aa)
initn: 722 init1: 722 opt: 723 Z-score: 711.0 bits: 141.5 E(85289): 7.3e-33
Smith-Waterman score: 723; 92.7% identity (96.8% similar) in 124 aa overlap (403-526:9-132)
380 390 400 410 420 430
pF1KE9 PYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMT
.: . . ..::::::::::::::::::::
XP_011 MRSYRIPLLVISSQESKTTGQKLYVRLFQRKLSWIKMT
10 20 30
440 450 460 470 480 490
pF1KE9 KLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQ
40 50 60 70 80 90
500 510 520 530
pF1KE9 KQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ
::::::::::::::::::::::::::::::::::
XP_011 KQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLF
100 110 120 130 140 150
XP_011 SLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHML
160 170 180 190 200 210
533 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:34:27 2016 done: Tue Nov 8 10:34:29 2016
Total Scan time: 7.380 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]