Result of FASTA (omim) for
pFN21AE9684
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9684, 838 aa
1>>>pF1KE9684 838 - 838 aa - 838 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.9181+/-0.000402; mu= -8.8816+/- 0.025
mean_var=341.1143+/-68.674, 0's: 0 Z-trim(122.8): 86 B-trim: 0 in 0/59
Lambda= 0.069442
statistics sampled from 41381 (41469) to 41381 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.486), width: 16
Scan time: 12.210
The best scores are: opt bits E(85289)
NP_006333 (OMIM: 605303) transforming acidic coile ( 838) 5514 566.6 1.7e-160
XP_016863142 (OMIM: 605303) PREDICTED: transformin ( 838) 5514 566.6 1.7e-160
XP_005247986 (OMIM: 605303) PREDICTED: transformin ( 842) 5496 564.8 5.9e-160
XP_011511688 (OMIM: 605303) PREDICTED: transformin ( 717) 4571 472.1 4.1e-132
XP_005247987 (OMIM: 605303) PREDICTED: transformin ( 482) 2387 253.1 2.1e-66
XP_011542937 (OMIM: 605301) PREDICTED: transformin ( 622) 827 96.9 3e-19
XP_005273687 (OMIM: 605301) PREDICTED: transformin ( 622) 827 96.9 3e-19
XP_016869259 (OMIM: 605301) PREDICTED: transformin ( 622) 827 96.9 3e-19
XP_016869260 (OMIM: 605301) PREDICTED: transformin ( 622) 827 96.9 3e-19
XP_005273686 (OMIM: 605301) PREDICTED: transformin ( 781) 829 97.2 3.1e-19
XP_005273685 (OMIM: 605301) PREDICTED: transformin ( 789) 829 97.2 3.1e-19
XP_005273682 (OMIM: 605301) PREDICTED: transformin ( 817) 829 97.2 3.2e-19
XP_011542934 (OMIM: 605301) PREDICTED: transformin ( 817) 829 97.2 3.2e-19
XP_011542933 (OMIM: 605301) PREDICTED: transformin ( 817) 829 97.2 3.2e-19
XP_011542936 (OMIM: 605301) PREDICTED: transformin ( 776) 711 85.4 1.1e-15
XP_016869258 (OMIM: 605301) PREDICTED: transformin ( 740) 707 84.9 1.4e-15
XP_016869257 (OMIM: 605301) PREDICTED: transformin ( 748) 707 84.9 1.4e-15
XP_005269453 (OMIM: 605302) PREDICTED: transformin (2922) 714 86.0 2.7e-15
XP_011542938 (OMIM: 605301) PREDICTED: transformin ( 367) 686 82.7 3.4e-15
NP_001116296 (OMIM: 605301) transforming acidic co ( 395) 686 82.7 3.6e-15
XP_016870985 (OMIM: 605302) PREDICTED: transformin ( 683) 692 83.4 3.8e-15
XP_016869262 (OMIM: 605301) PREDICTED: transformin ( 610) 689 83.1 4.2e-15
XP_016869261 (OMIM: 605301) PREDICTED: transformin ( 610) 689 83.1 4.2e-15
XP_016869263 (OMIM: 605301) PREDICTED: transformin ( 610) 689 83.1 4.2e-15
NP_001139688 (OMIM: 605301) transforming acidic co ( 610) 689 83.1 4.2e-15
XP_011537433 (OMIM: 605302) PREDICTED: transformin (1057) 694 83.7 4.7e-15
XP_016870980 (OMIM: 605302) PREDICTED: transformin (1074) 694 83.7 4.8e-15
XP_011537431 (OMIM: 605302) PREDICTED: transformin (1145) 694 83.8 5e-15
XP_016869256 (OMIM: 605301) PREDICTED: transformin ( 769) 689 83.2 5.1e-15
XP_016869255 (OMIM: 605301) PREDICTED: transformin ( 777) 689 83.2 5.2e-15
XP_011537430 (OMIM: 605302) PREDICTED: transformin (1190) 694 83.8 5.2e-15
NP_006274 (OMIM: 605301) transforming acidic coile ( 805) 689 83.2 5.3e-15
XP_016870982 (OMIM: 605302) PREDICTED: transformin ( 992) 691 83.4 5.5e-15
XP_011537435 (OMIM: 605302) PREDICTED: transformin ( 575) 684 82.6 5.7e-15
NP_001278808 (OMIM: 605302) transforming acidic co ( 575) 684 82.6 5.7e-15
XP_011537436 (OMIM: 605302) PREDICTED: transformin ( 575) 684 82.6 5.7e-15
XP_011542940 (OMIM: 605301) PREDICTED: transformin ( 338) 677 81.7 6e-15
XP_016870988 (OMIM: 605302) PREDICTED: transformin ( 634) 684 82.6 6.2e-15
NP_996742 (OMIM: 605302) transforming acidic coile ( 996) 689 83.2 6.3e-15
XP_011542939 (OMIM: 605301) PREDICTED: transformin ( 366) 677 81.8 6.4e-15
XP_016870986 (OMIM: 605302) PREDICTED: transformin ( 679) 684 82.6 6.5e-15
XP_016870987 (OMIM: 605302) PREDICTED: transformin ( 679) 684 82.6 6.5e-15
XP_016870984 (OMIM: 605302) PREDICTED: transformin ( 949) 685 82.8 8e-15
XP_016870983 (OMIM: 605302) PREDICTED: transformin ( 966) 685 82.8 8.1e-15
NP_001278807 (OMIM: 605302) transforming acidic co (1008) 684 82.7 9e-15
NP_008928 (OMIM: 605302) transforming acidic coile (1026) 684 82.7 9.2e-15
XP_011537434 (OMIM: 605302) PREDICTED: transformin (1038) 684 82.7 9.3e-15
XP_016870981 (OMIM: 605302) PREDICTED: transformin (1043) 684 82.7 9.3e-15
XP_016869267 (OMIM: 605301) PREDICTED: transformin ( 581) 677 81.9 9.3e-15
XP_016869265 (OMIM: 605301) PREDICTED: transformin ( 581) 677 81.9 9.3e-15
>>NP_006333 (OMIM: 605303) transforming acidic coiled-co (838 aa)
initn: 5514 init1: 5514 opt: 5514 Z-score: 3002.5 bits: 566.6 E(85289): 1.7e-160
Smith-Waterman score: 5514; 99.6% identity (99.8% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE9 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKENQQLIKEVDAKTTHGILQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKENQQLIKEVDAKTTHGILQK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PVEADTDLLGDASPAFGSGSSSESGPGALADLDCSSSSQSPGSSENQMVSPGKVSGSPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PVEADTDLLGDASPAFGSGSSSESGPGALADLDCSSSSQSPGSSENQMVSPGKVSGSPEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AVEENLSSYSLDRRVTPASETLEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AVEENLSSYSLDRRVTPASETLEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 VCAPAAVATSPPGAIPKEACGGAPLQGLPGEALGYPAGVGTPVPADSTQTLTCAHTSAPE
:::::::::::::::::::::::::::::::::: :::::::::::.:::::::::::::
NP_006 VCAPAAVATSPPGAIPKEACGGAPLQGLPGEALGCPAGVGTPVPADGTQTLTCAHTSAPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 STAPTNHLVAGRAMTLSPQEEVAAGQMASSSRSGPVKLEFDVSDGATSKRAPPPRRLGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 STAPTNHLVAGRAMTLSPQEEVAAGQMASSSRSGPVKLEFDVSDGATSKRAPPPRRLGER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 SGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 DTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 TPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAEVLGTGAEVDY
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_006 TPTAESKERALNSASTSLPTSCPGSEPVPTHQQGQPALELKEESFRDPAEVLGTGAEVDY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 LEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 VEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVKATQEENRELRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVKATQEENRELRS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 RCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 SFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANE
730 740 750 760 770 780
790 800 810 820 830
pF1KE9 EIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKMEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKMEKI
790 800 810 820 830
>>XP_016863142 (OMIM: 605303) PREDICTED: transforming ac (838 aa)
initn: 5514 init1: 5514 opt: 5514 Z-score: 3002.5 bits: 566.6 E(85289): 1.7e-160
Smith-Waterman score: 5514; 99.6% identity (99.8% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE9 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKENQQLIKEVDAKTTHGILQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKENQQLIKEVDAKTTHGILQK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PVEADTDLLGDASPAFGSGSSSESGPGALADLDCSSSSQSPGSSENQMVSPGKVSGSPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVEADTDLLGDASPAFGSGSSSESGPGALADLDCSSSSQSPGSSENQMVSPGKVSGSPEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AVEENLSSYSLDRRVTPASETLEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVEENLSSYSLDRRVTPASETLEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 VCAPAAVATSPPGAIPKEACGGAPLQGLPGEALGYPAGVGTPVPADSTQTLTCAHTSAPE
:::::::::::::::::::::::::::::::::: :::::::::::.:::::::::::::
XP_016 VCAPAAVATSPPGAIPKEACGGAPLQGLPGEALGCPAGVGTPVPADGTQTLTCAHTSAPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 STAPTNHLVAGRAMTLSPQEEVAAGQMASSSRSGPVKLEFDVSDGATSKRAPPPRRLGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAPTNHLVAGRAMTLSPQEEVAAGQMASSSRSGPVKLEFDVSDGATSKRAPPPRRLGER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 SGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 DTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 TPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAEVLGTGAEVDY
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_016 TPTAESKERALNSASTSLPTSCPGSEPVPTHQQGQPALELKEESFRDPAEVLGTGAEVDY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 LEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 VEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVKATQEENRELRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVKATQEENRELRS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 RCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 SFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANE
730 740 750 760 770 780
790 800 810 820 830
pF1KE9 EIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKMEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKMEKI
790 800 810 820 830
>>XP_005247986 (OMIM: 605303) PREDICTED: transforming ac (842 aa)
initn: 4495 init1: 4341 opt: 5496 Z-score: 2992.7 bits: 564.8 E(85289): 5.9e-160
Smith-Waterman score: 5496; 99.2% identity (99.3% similar) in 842 aa overlap (1-838:1-842)
10 20 30 40 50 60
pF1KE9 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKENQQLIKEVDAKTTHGILQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKENQQLIKEVDAKTTHGILQK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PVEADTDLLGDASPAFGSGSSSESGPGALADLDCSSSSQSPGSSENQMVSPGKVSGSPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVEADTDLLGDASPAFGSGSSSESGPGALADLDCSSSSQSPGSSENQMVSPGKVSGSPEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AVEENLSSYSLDRRVTPASETLEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVEENLSSYSLDRRVTPASETLEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 VCAPAAVATSPPGAIPKEACGGAPLQGLPGEALGYPAGVGTPVPADSTQTLTCAHTSAPE
:::::::::::::::::::::::::::::::::: :::::::::::.:::::::::::::
XP_005 VCAPAAVATSPPGAIPKEACGGAPLQGLPGEALGCPAGVGTPVPADGTQTLTCAHTSAPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 STAPTNHLVAGRAMTLSPQEEVAAGQMASSSRSGPVKLEFDVSDGATSKRAPPPRRLGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STAPTNHLVAGRAMTLSPQEEVAAGQMASSSRSGPVKLEFDVSDGATSKRAPPPRRLGER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 SGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 DTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 TPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAEVLGTGAEVDY
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_005 TPTAESKERALNSASTSLPTSCPGSEPVPTHQQGQPALELKEESFRDPAEVLGTGAEVDY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 LEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKL
550 560 570 580 590 600
610 620 630 640 650
pF1KE9 VEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVV----KATQEENR
:::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_005 VEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVRTQVKATQEENR
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE9 ELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLN
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE9 SMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQ
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE9 LANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKME
790 800 810 820 830 840
pF1KE9 KI
::
XP_005 KI
>>XP_011511688 (OMIM: 605303) PREDICTED: transforming ac (717 aa)
initn: 4459 init1: 4341 opt: 4571 Z-score: 2492.9 bits: 472.1 E(85289): 4.1e-132
Smith-Waterman score: 4571; 99.0% identity (99.1% similar) in 691 aa overlap (1-687:1-691)
10 20 30 40 50 60
pF1KE9 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVLRVSQKENVPPKNLAKAMKVTFQTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKENQQLIKEVDAKTTHGILQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDPQTHRILSPSMASKLEAPFTQDDTLGLENSHPVWTQKENQQLIKEVDAKTTHGILQK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PVEADTDLLGDASPAFGSGSSSESGPGALADLDCSSSSQSPGSSENQMVSPGKVSGSPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVEADTDLLGDASPAFGSGSSSESGPGALADLDCSSSSQSPGSSENQMVSPGKVSGSPEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AVEENLSSYSLDRRVTPASETLEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVEENLSSYSLDRRVTPASETLEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 VCAPAAVATSPPGAIPKEACGGAPLQGLPGEALGYPAGVGTPVPADSTQTLTCAHTSAPE
:::::::::::::::::::::::::::::::::: :::::::::::.:::::::::::::
XP_011 VCAPAAVATSPPGAIPKEACGGAPLQGLPGEALGCPAGVGTPVPADGTQTLTCAHTSAPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 STAPTNHLVAGRAMTLSPQEEVAAGQMASSSRSGPVKLEFDVSDGATSKRAPPPRRLGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STAPTNHLVAGRAMTLSPQEEVAAGQMASSSRSGPVKLEFDVSDGATSKRAPPPRRLGER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 SGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 DTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTKSGCSEAQPPESPETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 TPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAEVLGTGAEVDY
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 TPTAESKERALNSASTSLPTSCPGSEPVPTHQQGQPALELKEESFRDPAEVLGTGAEVDY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 LEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANETPSGRPREAKL
550 560 570 580 590 600
610 620 630 640 650
pF1KE9 VEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVV----KATQEENR
:::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 VEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVRTQVKATQEENR
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE9 ELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLN
:::::::::::::::::::::::::::::::
XP_011 ELRSRCEELHGKNLELGKIMDRFEEVVYQAMVPPGPPRSTTHILELAIPAPRPHPRL
670 680 690 700 710
720 730 740 750 760 770
pF1KE9 SMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQ
>>XP_005247987 (OMIM: 605303) PREDICTED: transforming ac (482 aa)
initn: 1925 init1: 1228 opt: 2387 Z-score: 1313.0 bits: 253.1 E(85289): 2.1e-66
Smith-Waterman score: 2394; 85.5% identity (90.3% similar) in 462 aa overlap (394-838:26-482)
370 380 390 400 410 420
pF1KE9 KPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDTK
:: ..:.: .... . .: . .:
XP_005 MSLQVLNDKNVSNEKNTENCDFLFSPPEVTGRSSVL----RVSQKENVPPKNLAK
10 20 30 40 50
430 440 450 460 470
pF1KE9 SGCSEAQPP-ESPET-RLGQPA-AEQLHAGPAT-------EEPGPCLSQ---QLHSASAE
. : : ..:.: :. .:. : .:.: : : :. : .: ::::::::
XP_005 AMKVTFQTPLRDPQTHRILSPSMASKLEA-PFTQDDTLGLENSHPVWTQKEKQLHSASAE
60 70 80 90 100 110
480 490 500 510 520 530
pF1KE9 DTPVVQLAAETPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAE
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_005 DTPVVQLAAETPTAESKERALNSASTSLPTSCPGSEPVPTHQQGQPALELKEESFRDPAE
120 130 140 150 160 170
540 550 560 570 580 590
pF1KE9 VLGTGAEVDYLEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLGTGAEVDYLEQFGTSSFKESALRKQSLYLKFDPLLRDSPGRPVPVATETSSMHGANET
180 190 200 210 220 230
600 610 620 630 640
pF1KE9 PSGRPREAKLVEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVV--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSGRPREAKLVEFDFLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVRT
240 250 260 270 280 290
650 660 670 680 690 700
pF1KE9 --KATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLK
300 310 320 330 340 350
710 720 730 740 750 760
pF1KE9 EKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQA
360 370 380 390 400 410
770 780 790 800 810 820
pF1KE9 LKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTR
420 430 440 450 460 470
830
pF1KE9 ICDDLISKMEKI
::::::::::::
XP_005 ICDDLISKMEKI
480
>>XP_011542937 (OMIM: 605301) PREDICTED: transforming ac (622 aa)
initn: 762 init1: 646 opt: 827 Z-score: 466.7 bits: 96.9 E(85289): 3e-19
Smith-Waterman score: 827; 32.3% identity (57.2% similar) in 647 aa overlap (232-837:14-620)
210 220 230 240 250 260
pF1KE9 LEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGGVCAPAAVATSPPGAIPKEACG
:: . . :. : . . :: .
XP_011 MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPV--
10 20 30 40
270 280 290 300 310
pF1KE9 GAPL--QGLPGEALGYPAGV-GTPVPADSTQTLTCAHTSAPESTAPTNHLVAGRAMTLSP
:: ... :: :.: :::.: : : : : :. :.. . ::
XP_011 --PLRKKAIGGEFSDTNAAVEGTPLPKASY------HFSPEELDENTSPLLGDARFQKSP
50 60 70 80 90
320 330 340 350 360
pF1KE9 QE-EVAAGQMASS-----------SRSGPVKLEFDVSD--GATSKRAPPPRRLGERSG--
. . . : ..:. :::.:.::::: .. : : ::.::.. :
XP_011 PDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGST
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE9 LKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDT
: : ..: .. .. . .. . .:.: : :. : . : .. ..:.: :::. .
XP_011 LTPKIQKDGISKSAGLEQPTDPVARDG-------PLSQTSSKPDPSQWESPSFNPFGSHS
160 170 180 190 200
430 440 450 460 470
pF1KE9 KSGCSEAQPPESPETRLGQPAAEQLHAGPAT--EEPGPCLSQQLHSASAEDTPV---VQL
. .:: : : :. : : . : : ..: .:. :.
XP_011 ---VLQNSPPLSSE---GS-----YHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNE
210 220 230 240 250
480 490 500 510 520 530
pF1KE9 AAETPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAEVLGTGAE
:.: ..: : : ... .. : ....: .: : : :: . :.. ..
XP_011 ILESPK-KAKSR-LITTTEQVKFLCFLLSGCKVKKHETQSLALDACS-RDEGAVISQISD
260 270 280 290 300 310
540 550 560 570 580 590
pF1KE9 VDYLEQFGTSSFKESAL----RKQSLYLKFDPL--LRDSPGRPVPVATETSSMHGANETP
.. . .:. : .. .. . .: .: :. :::.: . :. . .
XP_011 ISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTIN---HAFSSSE
320 330 340 350 360
600 610 620 630 640
pF1KE9 SGRPREA-KLVEFD---FLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAV
.: .:. . .: : :: :. . : .: : :: : . :..: ::
XP_011 AGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPL------DGICLSESDKTAV
370 380 390 400 410 420
650 660 670 680 690 700
pF1KE9 VKATQEE-------NRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAE
. .:: : ... :: . . ::. ::. ..:... : .:. :. . :.
XP_011 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS
430 440 450 460 470 480
710 720 730 740 750 760
pF1KE9 IQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQE
.:.. ::.: .::::.:.:.::::.:.:. : :.::..::::.::::..:::::. ::
XP_011 FQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQE
490 500 510 520 530 540
770 780 790 800 810 820
pF1KE9 GQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKE
::::::: ::::::. :::::::::.::.::. ::.:.::::::...:::....::..:
XP_011 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQE
550 560 570 580 590 600
830
pF1KE9 NEELTRICDDLISKMEKI
::::.:::.::.:. :
XP_011 IEELTKICDELIAKLGKTD
610 620
>>XP_005273687 (OMIM: 605301) PREDICTED: transforming ac (622 aa)
initn: 762 init1: 646 opt: 827 Z-score: 466.7 bits: 96.9 E(85289): 3e-19
Smith-Waterman score: 827; 32.3% identity (57.2% similar) in 647 aa overlap (232-837:14-620)
210 220 230 240 250 260
pF1KE9 LEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGGVCAPAAVATSPPGAIPKEACG
:: . . :. : . . :: .
XP_005 MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPV--
10 20 30 40
270 280 290 300 310
pF1KE9 GAPL--QGLPGEALGYPAGV-GTPVPADSTQTLTCAHTSAPESTAPTNHLVAGRAMTLSP
:: ... :: :.: :::.: : : : : :. :.. . ::
XP_005 --PLRKKAIGGEFSDTNAAVEGTPLPKASY------HFSPEELDENTSPLLGDARFQKSP
50 60 70 80 90
320 330 340 350 360
pF1KE9 QE-EVAAGQMASS-----------SRSGPVKLEFDVSD--GATSKRAPPPRRLGERSG--
. . . : ..:. :::.:.::::: .. : : ::.::.. :
XP_005 PDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGST
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE9 LKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDT
: : ..: .. .. . .. . .:.: : :. : . : .. ..:.: :::. .
XP_005 LTPKIQKDGISKSAGLEQPTDPVARDG-------PLSQTSSKPDPSQWESPSFNPFGSHS
160 170 180 190 200
430 440 450 460 470
pF1KE9 KSGCSEAQPPESPETRLGQPAAEQLHAGPAT--EEPGPCLSQQLHSASAEDTPV---VQL
. .:: : : :. : : . : : ..: .:. :.
XP_005 ---VLQNSPPLSSE---GS-----YHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNE
210 220 230 240 250
480 490 500 510 520 530
pF1KE9 AAETPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAEVLGTGAE
:.: ..: : : ... .. : ....: .: : : :: . :.. ..
XP_005 ILESPK-KAKSR-LITTTEQVKFLCFLLSGCKVKKHETQSLALDACS-RDEGAVISQISD
260 270 280 290 300 310
540 550 560 570 580 590
pF1KE9 VDYLEQFGTSSFKESAL----RKQSLYLKFDPL--LRDSPGRPVPVATETSSMHGANETP
.. . .:. : .. .. . .: .: :. :::.: . :. . .
XP_005 ISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTIN---HAFSSSE
320 330 340 350 360
600 610 620 630 640
pF1KE9 SGRPREA-KLVEFD---FLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAV
.: .:. . .: : :: :. . : .: : :: : . :..: ::
XP_005 AGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPL------DGICLSESDKTAV
370 380 390 400 410 420
650 660 670 680 690 700
pF1KE9 VKATQEE-------NRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAE
. .:: : ... :: . . ::. ::. ..:... : .:. :. . :.
XP_005 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS
430 440 450 460 470 480
710 720 730 740 750 760
pF1KE9 IQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQE
.:.. ::.: .::::.:.:.::::.:.:. : :.::..::::.::::..:::::. ::
XP_005 FQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQE
490 500 510 520 530 540
770 780 790 800 810 820
pF1KE9 GQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKE
::::::: ::::::. :::::::::.::.::. ::.:.::::::...:::....::..:
XP_005 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQE
550 560 570 580 590 600
830
pF1KE9 NEELTRICDDLISKMEKI
::::.:::.::.:. :
XP_005 IEELTKICDELIAKLGKTD
610 620
>>XP_016869259 (OMIM: 605301) PREDICTED: transforming ac (622 aa)
initn: 762 init1: 646 opt: 827 Z-score: 466.7 bits: 96.9 E(85289): 3e-19
Smith-Waterman score: 827; 32.3% identity (57.2% similar) in 647 aa overlap (232-837:14-620)
210 220 230 240 250 260
pF1KE9 LEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGGVCAPAAVATSPPGAIPKEACG
:: . . :. : . . :: .
XP_016 MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPV--
10 20 30 40
270 280 290 300 310
pF1KE9 GAPL--QGLPGEALGYPAGV-GTPVPADSTQTLTCAHTSAPESTAPTNHLVAGRAMTLSP
:: ... :: :.: :::.: : : : : :. :.. . ::
XP_016 --PLRKKAIGGEFSDTNAAVEGTPLPKASY------HFSPEELDENTSPLLGDARFQKSP
50 60 70 80 90
320 330 340 350 360
pF1KE9 QE-EVAAGQMASS-----------SRSGPVKLEFDVSD--GATSKRAPPPRRLGERSG--
. . . : ..:. :::.:.::::: .. : : ::.::.. :
XP_016 PDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGST
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE9 LKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDT
: : ..: .. .. . .. . .:.: : :. : . : .. ..:.: :::. .
XP_016 LTPKIQKDGISKSAGLEQPTDPVARDG-------PLSQTSSKPDPSQWESPSFNPFGSHS
160 170 180 190 200
430 440 450 460 470
pF1KE9 KSGCSEAQPPESPETRLGQPAAEQLHAGPAT--EEPGPCLSQQLHSASAEDTPV---VQL
. .:: : : :. : : . : : ..: .:. :.
XP_016 ---VLQNSPPLSSE---GS-----YHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNE
210 220 230 240 250
480 490 500 510 520 530
pF1KE9 AAETPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAEVLGTGAE
:.: ..: : : ... .. : ....: .: : : :: . :.. ..
XP_016 ILESPK-KAKSR-LITTTEQVKFLCFLLSGCKVKKHETQSLALDACS-RDEGAVISQISD
260 270 280 290 300 310
540 550 560 570 580 590
pF1KE9 VDYLEQFGTSSFKESAL----RKQSLYLKFDPL--LRDSPGRPVPVATETSSMHGANETP
.. . .:. : .. .. . .: .: :. :::.: . :. . .
XP_016 ISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTIN---HAFSSSE
320 330 340 350 360
600 610 620 630 640
pF1KE9 SGRPREA-KLVEFD---FLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAV
.: .:. . .: : :: :. . : .: : :: : . :..: ::
XP_016 AGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPL------DGICLSESDKTAV
370 380 390 400 410 420
650 660 670 680 690 700
pF1KE9 VKATQEE-------NRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAE
. .:: : ... :: . . ::. ::. ..:... : .:. :. . :.
XP_016 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS
430 440 450 460 470 480
710 720 730 740 750 760
pF1KE9 IQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQE
.:.. ::.: .::::.:.:.::::.:.:. : :.::..::::.::::..:::::. ::
XP_016 FQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQE
490 500 510 520 530 540
770 780 790 800 810 820
pF1KE9 GQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKE
::::::: ::::::. :::::::::.::.::. ::.:.::::::...:::....::..:
XP_016 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQE
550 560 570 580 590 600
830
pF1KE9 NEELTRICDDLISKMEKI
::::.:::.::.:. :
XP_016 IEELTKICDELIAKLGKTD
610 620
>>XP_016869260 (OMIM: 605301) PREDICTED: transforming ac (622 aa)
initn: 762 init1: 646 opt: 827 Z-score: 466.7 bits: 96.9 E(85289): 3e-19
Smith-Waterman score: 827; 32.3% identity (57.2% similar) in 647 aa overlap (232-837:14-620)
210 220 230 240 250 260
pF1KE9 LEDPCRTESQHKAETPHGAEEECKAETPHGAEEECRHGGVCAPAAVATSPPGAIPKEACG
:: . . :. : . . :: .
XP_016 MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPV--
10 20 30 40
270 280 290 300 310
pF1KE9 GAPL--QGLPGEALGYPAGV-GTPVPADSTQTLTCAHTSAPESTAPTNHLVAGRAMTLSP
:: ... :: :.: :::.: : : : : :. :.. . ::
XP_016 --PLRKKAIGGEFSDTNAAVEGTPLPKASY------HFSPEELDENTSPLLGDARFQKSP
50 60 70 80 90
320 330 340 350 360
pF1KE9 QE-EVAAGQMASS-----------SRSGPVKLEFDVSD--GATSKRAPPPRRLGERSG--
. . . : ..:. :::.:.::::: .. : : ::.::.. :
XP_016 PDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGST
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE9 LKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDT
: : ..: .. .. . .. . .:.: : :. : . : .. ..:.: :::. .
XP_016 LTPKIQKDGISKSAGLEQPTDPVARDG-------PLSQTSSKPDPSQWESPSFNPFGSHS
160 170 180 190 200
430 440 450 460 470
pF1KE9 KSGCSEAQPPESPETRLGQPAAEQLHAGPAT--EEPGPCLSQQLHSASAEDTPV---VQL
. .:: : : :. : : . : : ..: .:. :.
XP_016 ---VLQNSPPLSSE---GS-----YHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNE
210 220 230 240 250
480 490 500 510 520 530
pF1KE9 AAETPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPALELKEESFRDPAEVLGTGAE
:.: ..: : : ... .. : ....: .: : : :: . :.. ..
XP_016 ILESPK-KAKSR-LITTTEQVKFLCFLLSGCKVKKHETQSLALDACS-RDEGAVISQISD
260 270 280 290 300 310
540 550 560 570 580 590
pF1KE9 VDYLEQFGTSSFKESAL----RKQSLYLKFDPL--LRDSPGRPVPVATETSSMHGANETP
.. . .:. : .. .. . .: .: :. :::.: . :. . .
XP_016 ISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTIN---HAFSSSE
320 330 340 350 360
600 610 620 630 640
pF1KE9 SGRPREA-KLVEFD---FLGALDIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAV
.: .:. . .: : :: :. . : .: : :: : . :..: ::
XP_016 AGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPL------DGICLSESDKTAV
370 380 390 400 410 420
650 660 670 680 690 700
pF1KE9 VKATQEE-------NRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAE
. .:: : ... :: . . ::. ::. ..:... : .:. :. . :.
XP_016 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS
430 440 450 460 470 480
710 720 730 740 750 760
pF1KE9 IQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQE
.:.. ::.: .::::.:.:.::::.:.:. : :.::..::::.::::..:::::. ::
XP_016 FQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQE
490 500 510 520 530 540
770 780 790 800 810 820
pF1KE9 GQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKE
::::::: ::::::. :::::::::.::.::. ::.:.::::::...:::....::..:
XP_016 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQE
550 560 570 580 590 600
830
pF1KE9 NEELTRICDDLISKMEKI
::::.:::.::.:. :
XP_016 IEELTKICDELIAKLGKTD
610 620
>>XP_005273686 (OMIM: 605301) PREDICTED: transforming ac (781 aa)
initn: 767 init1: 646 opt: 829 Z-score: 466.3 bits: 97.2 E(85289): 3.1e-19
Smith-Waterman score: 864; 30.6% identity (55.7% similar) in 787 aa overlap (118-837:34-779)
90 100 110 120 130 140
pF1KE9 LGLENSHPVWTQKENQQLIKEVDAKTTHGILQKPVEADTD-LLGDASPAFGSGSSSESGP
...: . . : :: :.:. : :.:.
XP_005 LPSTLRSNAKTNHQSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADE
10 20 30 40 50 60
150 160 170 180 190 200
pF1KE9 GALADL--DCSSSSQS-PGSSE--NQMVSPGKVSGSPEQAVEENLSSYSLDRRVTPASET
.:.. :::.. : :. .: .: .. .:.. :. :...:. :. : . ..
XP_005 QLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEP-EHDFSKISIVRPFSIETKD
70 80 90 100 110 120
210 220 230 240
pF1KE9 LED-----------PCRTESQHKA---ETPHGAEEECKAETPHG------AEEECRHGGV
: : : . :: : . ..: .: : :: . . :.
XP_005 STDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNS
130 140 150 160 170 180
250 260 270 280 290
pF1KE9 CAPAAVATSPPGAIPKEACGGAPL--QGLPGEALGYPAGV-GTPVPADSTQTLTCAHTSA
: . . :: . :: ... :: :.: :::.: : : :
XP_005 CPELVPSRRSKLRKPKPV----PLRKKAIGGEFSDTNAAVEGTPLPKASY------HFSP
190 200 210 220 230
300 310 320 330 340
pF1KE9 PESTAPTNHLVAGRAMTLSPQE-EVAAGQMASS-----------SRSGPVKLEFDVSD--
: :. :.. . :: . . . : ..:. :::.:.::::: ..
XP_005 EELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDT
240 250 260 270 280 290
350 360 370 380 390 400
pF1KE9 GATSKRAPPPRRLGERSG--LKPPLRKAAVRQQKAPQEVEEDDGRSGAGEDPPMPASRGS
: : ::.::.. : : : ..: .. .. . .. . .:.: : :. :
XP_005 GNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDG-------PLSQTS
300 310 320 330 340
410 420 430 440 450 460
pF1KE9 YHLDWDKMDDPNFIPFGGDTKSGCSEAQPPESPETRLGQPAAEQLHAGPAT--EEPGPCL
. : .. ..:.: :::. . . .:: : : :. : : . : :
XP_005 SKPDPSQWESPSFNPFGSHS---VLQNSPPLSSE---GS-----YHFDPDNFDESMDPFK
350 360 370 380 390
470 480 490 500 510
pF1KE9 SQQLHSASAEDTPV---VQLAAETPTAESKERALNSASTSLPTSCPGSEPVPTHQQEQPA
..: .:. :. :.: ..: : : ... .. : ....: .
XP_005 PTTTLTSSDFCSPTGNHVNEILESPK-KAKSR-LITTTEQVKFLCFLLSGCKVKKHETQS
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE9 LELKEESFRDPAEVLGTGAEVDYLEQFGTSSFKESAL----RKQSLYLKFDPL--LRDSP
: : : :: . :.. .... . .:. : .. .. . .: .: :.
XP_005 LALDACS-RDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFE
460 470 480 490 500 510
580 590 600 610 620
pF1KE9 GRPVPVATETSSMHGANETPSGRPREA-KLVEFD---FLGALDIPVPGPPPGVPAPGGPP
:::.: . :. . . .: .:. . .: : :: :. . : .: : :
XP_005 CSNVPVSTIN---HAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESP
520 530 540 550 560
630 640 650 660 670 680
pF1KE9 LSTGPIVDLLQYSQKDLDAVVKATQEE-------NRELRSRCEELHGKNLELGKIMDRFE
: : . :..: ::. .:: : ... :: . . ::. ::. ..:
XP_005 L------DGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYE
570 580 590 600 610 620
690 700 710 720 730 740
pF1KE9 EVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYR
... : .:. :. . :. .:.. ::.: .::::.:.:.::::.:.:. : :.::..
XP_005 KTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFK
630 640 650 660 670 680
750 760 770 780 790 800
pF1KE9 KNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASL
::::.::::..:::::. :: ::::::: ::::::. :::::::::.::.::. ::.:.:
XP_005 KNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGL
690 700 710 720 730 740
810 820 830
pF1KE9 RKEQMRIQSLEKTVEQKTKENEELTRICDDLISKMEKI
:::::...:::....::..: ::::.:::.::.:. :
XP_005 RKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
750 760 770 780
838 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:32:42 2016 done: Tue Nov 8 10:32:43 2016
Total Scan time: 12.210 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]