Result of FASTA (omim) for
pFN21AE9678
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9678, 1417 aa
1>>>pF1KE9678 1417 - 1417 aa - 1417 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7380+/-0.00045; mu= 17.2678+/- 0.028
mean_var=140.2989+/-29.156, 0's: 0 Z-trim(114.0): 120 B-trim: 713 in 2/56
Lambda= 0.108280
statistics sampled from 23533 (23683) to 23533 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.278), width: 16
Scan time: 15.730
The best scores are: opt bits E(85289)
NP_001274175 (OMIM: 210900,604610) Bloom syndrome (1417) 9341 1472.5 0
NP_000048 (OMIM: 210900,604610) Bloom syndrome pro (1417) 9341 1472.5 0
NP_001274176 (OMIM: 210900,604610) Bloom syndrome (1286) 7473 1180.6 0
NP_001274177 (OMIM: 210900,604610) Bloom syndrome (1042) 6908 1092.3 0
XP_011520183 (OMIM: 210900,604610) PREDICTED: Bloo ( 979) 6478 1025.1 0
XP_011520184 (OMIM: 210900,604610) PREDICTED: Bloo ( 907) 5594 887.0 0
XP_006720695 (OMIM: 210900,604610) PREDICTED: Bloo ( 763) 5049 801.8 0
NP_116559 (OMIM: 600537) ATP-dependent DNA helicas ( 649) 1156 193.6 4.2e-48
XP_005253520 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 1156 193.6 4.2e-48
XP_005253518 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 1156 193.6 4.2e-48
XP_005253521 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 1156 193.6 4.2e-48
NP_002898 (OMIM: 600537) ATP-dependent DNA helicas ( 649) 1156 193.6 4.2e-48
XP_005253519 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 1156 193.6 4.2e-48
NP_001003716 (OMIM: 603781) ATP-dependent DNA heli ( 410) 818 140.6 2.4e-32
NP_001003715 (OMIM: 603781) ATP-dependent DNA heli ( 435) 818 140.6 2.5e-32
XP_016880833 (OMIM: 603781) PREDICTED: ATP-depende ( 435) 818 140.6 2.5e-32
XP_005257880 (OMIM: 603781) PREDICTED: ATP-depende ( 549) 818 140.7 2.9e-32
NP_004250 (OMIM: 603781) ATP-dependent DNA helicas ( 991) 818 140.9 4.5e-32
XP_016880832 (OMIM: 603781) PREDICTED: ATP-depende ( 991) 818 140.9 4.5e-32
XP_011523784 (OMIM: 603781) PREDICTED: ATP-depende (1012) 818 140.9 4.6e-32
XP_005257875 (OMIM: 603781) PREDICTED: ATP-depende (1012) 818 140.9 4.6e-32
XP_011542942 (OMIM: 277700,604611) PREDICTED: Wern ( 899) 653 115.1 2.4e-24
XP_011542941 (OMIM: 277700,604611) PREDICTED: Wern (1405) 653 115.3 3.3e-24
NP_000544 (OMIM: 277700,604611) Werner syndrome AT (1432) 653 115.3 3.4e-24
XP_016869486 (OMIM: 218600,266280,268400,603780) P (1254) 380 72.6 2.1e-11
XP_011515686 (OMIM: 218600,266280,268400,603780) P (1142) 367 70.5 8.1e-11
XP_016869488 (OMIM: 218600,266280,268400,603780) P (1224) 367 70.6 8.5e-11
NP_001307524 (OMIM: 180630) probable ATP-dependent ( 614) 294 58.9 1.4e-07
NP_001307526 (OMIM: 180630) probable ATP-dependent ( 614) 294 58.9 1.4e-07
NP_001307525 (OMIM: 180630) probable ATP-dependent ( 614) 294 58.9 1.4e-07
NP_004387 (OMIM: 180630) probable ATP-dependent RN ( 614) 294 58.9 1.4e-07
XP_016869490 (OMIM: 218600,266280,268400,603780) P ( 911) 287 57.9 4e-07
XP_016869489 (OMIM: 218600,266280,268400,603780) P ( 941) 287 58.0 4.1e-07
NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729) 284 57.4 4.7e-07
NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731) 284 57.4 4.7e-07
NP_004251 (OMIM: 218600,266280,268400,603780) ATP- (1208) 287 58.1 4.9e-07
XP_016869487 (OMIM: 218600,266280,268400,603780) P (1238) 287 58.1 5e-07
XP_016869485 (OMIM: 218600,266280,268400,603780) P (1263) 287 58.1 5e-07
XP_016869484 (OMIM: 218600,266280,268400,603780) P (1265) 287 58.1 5e-07
XP_016869483 (OMIM: 218600,266280,268400,603780) P (1288) 287 58.1 5.1e-07
XP_016869482 (OMIM: 218600,266280,268400,603780) P (1290) 287 58.1 5.1e-07
XP_016869481 (OMIM: 218600,266280,268400,603780) P (1295) 287 58.1 5.1e-07
XP_016869480 (OMIM: 218600,266280,268400,603780) P (1320) 287 58.1 5.2e-07
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 255 52.7 7.6e-06
NP_004388 (OMIM: 600326) probable ATP-dependent RN ( 483) 234 49.4 7.8e-05
NP_001244120 (OMIM: 600326) probable ATP-dependent ( 483) 234 49.4 7.8e-05
XP_005271474 (OMIM: 600326) PREDICTED: probable AT ( 483) 234 49.4 7.8e-05
NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 234 49.5 9.3e-05
XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 234 49.5 9.3e-05
XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 234 49.5 9.3e-05
>>NP_001274175 (OMIM: 210900,604610) Bloom syndrome prot (1417 aa)
initn: 9341 init1: 9341 opt: 9341 Z-score: 7890.3 bits: 1472.5 E(85289): 0
Smith-Waterman score: 9341; 100.0% identity (100.0% similar) in 1417 aa overlap (1-1417:1-1417)
10 20 30 40 50 60
pF1KE9 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 QKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE9 LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE9 VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS
1330 1340 1350 1360 1370 1380
1390 1400 1410
pF1KE9 SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
:::::::::::::::::::::::::::::::::::::
NP_001 SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
1390 1400 1410
>>NP_000048 (OMIM: 210900,604610) Bloom syndrome protein (1417 aa)
initn: 9341 init1: 9341 opt: 9341 Z-score: 7890.3 bits: 1472.5 E(85289): 0
Smith-Waterman score: 9341; 100.0% identity (100.0% similar) in 1417 aa overlap (1-1417:1-1417)
10 20 30 40 50 60
pF1KE9 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 QKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE9 LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE9 VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS
1330 1340 1350 1360 1370 1380
1390 1400 1410
pF1KE9 SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
:::::::::::::::::::::::::::::::::::::
NP_000 SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
1390 1400 1410
>>NP_001274176 (OMIM: 210900,604610) Bloom syndrome prot (1286 aa)
initn: 7515 init1: 7473 opt: 7473 Z-score: 6313.8 bits: 1180.6 E(85289): 0
Smith-Waterman score: 8250; 90.8% identity (90.8% similar) in 1417 aa overlap (1-1417:1-1286)
10 20 30 40 50 60
pF1KE9 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRH
:::::::::::::::::::::::::::::::::::::::
NP_001 VKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFL---------------------
1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE9 NAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKK
NP_001 ------------------------------------------------------------
1210 1220 1230 1240 1250 1260
pF1KE9 QKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVL
::::::::::
NP_001 --------------------------------------------------ESLSSDPEVL
1120
1270 1280 1290 1300 1310 1320
pF1KE9 LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIP
1130 1140 1150 1160 1170 1180
1330 1340 1350 1360 1370 1380
pF1KE9 VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSS
1190 1200 1210 1220 1230 1240
1390 1400 1410
pF1KE9 SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
:::::::::::::::::::::::::::::::::::::
NP_001 SASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
1250 1260 1270 1280
>>NP_001274177 (OMIM: 210900,604610) Bloom syndrome prot (1042 aa)
initn: 6908 init1: 6908 opt: 6908 Z-score: 5838.0 bits: 1092.3 E(85289): 0
Smith-Waterman score: 6908; 100.0% identity (100.0% similar) in 1042 aa overlap (376-1417:1-1042)
350 360 370 380 390 400
pF1KE9 EKMSMQELNPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRN
::::::::::::::::::::::::::::::
NP_001 MEHICKLIDTIPDDKLKLLDCGNELLQQRN
10 20 30
410 420 430 440 450 460
pF1KE9 IRRKLLTEVDFNKSDASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRRKLLTEVDFNKSDASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSP
40 50 60 70 80 90
470 480 490 500 510 520
pF1KE9 GDCLLTTTLGKTGFSATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDCLLTTTLGKTGFSATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVL
100 110 120 130 140 150
530 540 550 560 570 580
pF1KE9 TSTAVKDQNKHTASINDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSTAVKDQNKHTASINDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQ
160 170 180 190 200 210
590 600 610 620 630 640
pF1KE9 PIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIKEGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQ
220 230 240 250 260 270
650 660 670 680 690 700
pF1KE9 SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACV
280 290 300 310 320 330
710 720 730 740 750 760
pF1KE9 SPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYV
340 350 360 370 380 390
770 780 790 800 810 820
pF1KE9 TPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVP
400 410 420 430 440 450
830 840 850 860 870 880
pF1KE9 VMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKH
460 470 480 490 500 510
890 900 910 920 930 940
pF1KE9 HPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICA
520 530 540 550 560 570
950 960 970 980 990 1000
pF1KE9 TIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLI
580 590 600 610 620 630
1010 1020 1030 1040 1050 1060
pF1KE9 MMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDN
640 650 660 670 680 690
1070 1080 1090 1100 1110 1120
pF1KE9 CCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAK
700 710 720 730 740 750
1130 1140 1150 1160 1170 1180
pF1KE9 IQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNL
760 770 780 790 800 810
1190 1200 1210 1220 1230 1240
pF1KE9 KVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVT
820 830 840 850 860 870
1250 1260 1270 1280 1290 1300
pF1KE9 LKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSR
880 890 900 910 920 930
1310 1320 1330 1340 1350 1360
pF1KE9 GPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCR
940 950 960 970 980 990
1370 1380 1390 1400 1410
pF1KE9 KISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
1000 1010 1020 1030 1040
>>XP_011520183 (OMIM: 210900,604610) PREDICTED: Bloom sy (979 aa)
initn: 6478 init1: 6478 opt: 6478 Z-score: 5475.3 bits: 1025.1 E(85289): 0
Smith-Waterman score: 6478; 100.0% identity (100.0% similar) in 979 aa overlap (439-1417:1-979)
410 420 430 440 450 460
pF1KE9 KLLTEVDFNKSDASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDC
::::::::::::::::::::::::::::::
XP_011 MEGDSCPTGNSMKELNFSHLPSNSVSPGDC
10 20 30
470 480 490 500 510 520
pF1KE9 LLTTTLGKTGFSATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTTTLGKTGFSATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTST
40 50 60 70 80 90
530 540 550 560 570 580
pF1KE9 AVKDQNKHTASINDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVKDQNKHTASINDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIK
100 110 120 130 140 150
590 600 610 620 630 640
pF1KE9 EGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGRPIKSVSERLSSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLS
160 170 180 190 200 210
650 660 670 680 690 700
pF1KE9 FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPG
220 230 240 250 260 270
710 720 730 740 750 760
pF1KE9 VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPE
280 290 300 310 320 330
770 780 790 800 810 820
pF1KE9 KICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMA
340 350 360 370 380 390
830 840 850 860 870 880
pF1KE9 LTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIRKHHPY
400 410 420 430 440 450
890 900 910 920 930 940
pF1KE9 DSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIA
460 470 480 490 500 510
950 960 970 980 990 1000
pF1KE9 FGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMME
520 530 540 550 560 570
1010 1020 1030 1040 1050 1060
pF1KE9 KDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCK
580 590 600 610 620 630
1070 1080 1090 1100 1110 1120
pF1KE9 TKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQS
640 650 660 670 680 690
1130 1140 1150 1160 1170 1180
pF1KE9 GIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIFGKGSAYSRHNAERLFKKLILDKILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVD
700 710 720 730 740 750
1190 1200 1210 1220 1230 1240
pF1KE9 FMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMETENSSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKK
760 770 780 790 800 810
1250 1260 1270 1280 1290 1300
pF1KE9 LAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDSSPGISLSSSRGPG
820 830 840 850 860 870
1310 1320 1330 1340 1350 1360
pF1KE9 RSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQRSKRRKTASSGSKAKGGSATCRKIS
880 890 900 910 920 930
1370 1380 1390 1400 1410
pF1KE9 SKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKPINRPFLKPSYAFS
940 950 960 970
>>XP_011520184 (OMIM: 210900,604610) PREDICTED: Bloom sy (907 aa)
initn: 5592 init1: 5592 opt: 5594 Z-score: 4729.4 bits: 887.0 E(85289): 0
Smith-Waterman score: 5597; 95.6% identity (96.6% similar) in 901 aa overlap (1-887:1-901)
10 20 30 40 50 60
pF1KE9 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKTSSDNNVSVTNVSVAKTPVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNKDVNVTEDFSFSEPLPNTTNQQRVKDFFKNAPAGQETQRGGSKSLLPDFLQTPKEVVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTQNTPTVKKSRDTALKKLEFSSSPDSLSTINDWDDMDDFDTSETSKSFVTPPQSHFVRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STAQKSKKGKRNFFKAQLYTTNTVKTDLPPPSSESEQIDLTEEQKDDSEWLSSDVICIDD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPIAEVHINEDAQESDSLKTHLEDERDNSEKKKNLEEAELHSTEKVPCIEFDDDDYDTDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQELNPETSTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTEVDFNKSD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLLGSLWRYRPDSLDGPMEGDSCPTGNSMKELNFSHLPSNSVSPGDCLLTTTLGKTGFS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATRKNLFERPLFNTHLQKSFVSSNWAETPRLGKKNESSYFPGNVLTSTAVKDQNKHTASI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDLERETQPSYDIDNFDIDDFDDDDDWEDIMHNLAASKSSTAAYQPIKEGRPIKSVSERL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSAKTDCLPVSSTAQNINFSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKD
790 800 810 820 830 840
850 860 870 880
pF1KE9 ILTQLKILRPQV---------FSMSFNRHNLKYYVLPKKPKKVAFDC-----LEWIRKHH
:::::::::::: :. .. . .: : :. . . : : . : :
XP_011 ILTQLKILRPQVIVQPSPISKFTAFLSPQRETWYPLAAAPHLLPLVCARLLSLSVVFKGH
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE9 PYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICAT
:
XP_011 PCCSIGQ
>>XP_006720695 (OMIM: 210900,604610) PREDICTED: Bloom sy (763 aa)
initn: 5049 init1: 5049 opt: 5049 Z-score: 4270.3 bits: 801.8 E(85289): 0
Smith-Waterman score: 5049; 100.0% identity (100.0% similar) in 763 aa overlap (655-1417:1-763)
630 640 650 660 670 680
pF1KE9 NYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGED
::::::::::::::::::::::::::::::
XP_006 MMKIFHKKFGLHNFRTNQLEAINAALLGED
10 20 30
690 700 710 720 730 740
pF1KE9 CFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDS
40 50 60 70 80 90
750 760 770 780 790 800
pF1KE9 EATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWG
100 110 120 130 140 150
810 820 830 840 850 860
pF1KE9 HDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKY
160 170 180 190 200 210
870 880 890 900 910 920
pF1KE9 YVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVLPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSD
220 230 240 250 260 270
930 940 950 960 970 980
pF1KE9 SARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDG
280 290 300 310 320 330
990 1000 1010 1020 1030 1040
pF1KE9 EISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAY
340 350 360 370 380 390
1050 1060 1070 1080 1090 1100
pF1KE9 FGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQGMRNIKHVG
400 410 420 430 440 450
1110 1120 1130 1140 1150 1160
pF1KE9 PSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSGRFTMNMLVDIFLGSKSAKIQSGIFGKGSAYSRHNAERLFKKLILDKILDEDLYINAN
460 470 480 490 500 510
1170 1180 1190 1200 1210 1220
pF1KE9 DQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREEMVKKCLGELTE
520 530 540 550 560 570
1230 1240 1250 1260 1270 1280
pF1KE9 VCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQK
580 590 600 610 620 630
1290 1300 1310 1320 1330 1340
pF1KE9 YSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YSEWTSPAEDSSPGISLSSSRGPGRSAAEELDEEIPVSSHYFASKTRNERKRKKMPASQR
640 650 660 670 680 690
1350 1360 1370 1380 1390 1400
pF1KE9 SKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKRRKTASSGSKAKGGSATCRKISSKTKSSSIIGSSSASHTSQATSGANSKLGIMAPPKP
700 710 720 730 740 750
1410
pF1KE9 INRPFLKPSYAFS
:::::::::::::
XP_006 INRPFLKPSYAFS
760
>>NP_116559 (OMIM: 600537) ATP-dependent DNA helicase Q1 (649 aa)
initn: 1215 init1: 632 opt: 1156 Z-score: 984.5 bits: 193.6 E(85289): 4.2e-48
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (649-1210:73-604)
620 630 640 650 660 670
pF1KE9 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
:: . .. :... : :..:: :::.::.
NP_116 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
50 60 70 80 90 100
680 690 700 710 720 730
pF1KE9 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
.. :.. :..::::::::::::::: : : :.:: :: ::. ::.. : .: : ::.:.
NP_116 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
110 120 130 140 150 160
740 750 760 770 780 790
pF1KE9 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
.... .. .. .. .:. .::.::::::: :. ..: ::. :: . ..:...::.:
NP_116 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
170 180 190 200 210 220
800 810 820 830 840 850
pF1KE9 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
: :::::::: ::: ...:...::.. ...:::::. .: : : : . .:. :::
NP_116 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
230 240 250 260 270 280
860 870 880 890 900 910
pF1KE9 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
: :: :: . .::... : : .. : .. .::::::.:... . .. .:: :. :
NP_116 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
290 300 310 320 330 340
920 930 940 950 960 970
pF1KE9 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
::::.: . :..:: . . ::. ::.:::::::::::::::: :. ::.:.:::
NP_116 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
350 360 370 380 390 400
980 990 1000 1010 1020 1030
pF1KE9 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
:::::::: . :.:.: . :. :.. ...::. :... :: :: ::.::..
NP_116 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
410 420 430 440 450
1040 1050 1060 1070 1080 1090
pF1KE9 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
:::. . .: : .: . :.: :::::: . .. ...:. ....... : . .
NP_116 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
460 470 480 490 500
1100 1110 1120 1130 1140 1150
pF1KE9 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
. . .: :.: ..:. .::.. .:. . . :.. :... ......
NP_116 EKLTPLK------------LIDSWMGKGAAKLRVAGVVA--PTLPREDLEKIIAHFLIQQ
510 520 530 540 550
1160 1170 1180 1190 1200 1210
pF1KE9 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
: :: ..: .:.:. .: ::. .::.. .. :.. .:. :... :. ::
NP_116 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
560 570 580 590 600
1220 1230 1240 1250 1260 1270
pF1KE9 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
NP_116 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
>>XP_005253520 (OMIM: 600537) PREDICTED: ATP-dependent D (649 aa)
initn: 1215 init1: 632 opt: 1156 Z-score: 984.5 bits: 193.6 E(85289): 4.2e-48
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (649-1210:73-604)
620 630 640 650 660 670
pF1KE9 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
:: . .. :... : :..:: :::.::.
XP_005 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
50 60 70 80 90 100
680 690 700 710 720 730
pF1KE9 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
.. :.. :..::::::::::::::: : : :.:: :: ::. ::.. : .: : ::.:.
XP_005 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
110 120 130 140 150 160
740 750 760 770 780 790
pF1KE9 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
.... .. .. .. .:. .::.::::::: :. ..: ::. :: . ..:...::.:
XP_005 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
170 180 190 200 210 220
800 810 820 830 840 850
pF1KE9 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
: :::::::: ::: ...:...::.. ...:::::. .: : : : . .:. :::
XP_005 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
230 240 250 260 270 280
860 870 880 890 900 910
pF1KE9 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
: :: :: . .::... : : .. : .. .::::::.:... . .. .:: :. :
XP_005 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
290 300 310 320 330 340
920 930 940 950 960 970
pF1KE9 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
::::.: . :..:: . . ::. ::.:::::::::::::::: :. ::.:.:::
XP_005 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
350 360 370 380 390 400
980 990 1000 1010 1020 1030
pF1KE9 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
:::::::: . :.:.: . :. :.. ...::. :... :: :: ::.::..
XP_005 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
410 420 430 440 450
1040 1050 1060 1070 1080 1090
pF1KE9 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
:::. . .: : .: . :.: :::::: . .. ...:. ....... : . .
XP_005 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
460 470 480 490 500
1100 1110 1120 1130 1140 1150
pF1KE9 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
. . .: :.: ..:. .::.. .:. . . :.. :... ......
XP_005 EKLTPLK------------LIDSWMGKGAAKLRVAGVVA--PTLPREDLEKIIAHFLIQQ
510 520 530 540 550
1160 1170 1180 1190 1200 1210
pF1KE9 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
: :: ..: .:.:. .: ::. .::.. .. :.. .:. :... :. ::
XP_005 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
560 570 580 590 600
1220 1230 1240 1250 1260 1270
pF1KE9 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
XP_005 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
>>XP_005253518 (OMIM: 600537) PREDICTED: ATP-dependent D (649 aa)
initn: 1215 init1: 632 opt: 1156 Z-score: 984.5 bits: 193.6 E(85289): 4.2e-48
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (649-1210:73-604)
620 630 640 650 660 670
pF1KE9 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
:: . .. :... : :..:: :::.::.
XP_005 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
50 60 70 80 90 100
680 690 700 710 720 730
pF1KE9 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
.. :.. :..::::::::::::::: : : :.:: :: ::. ::.. : .: : ::.:.
XP_005 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
110 120 130 140 150 160
740 750 760 770 780 790
pF1KE9 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
.... .. .. .. .:. .::.::::::: :. ..: ::. :: . ..:...::.:
XP_005 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
170 180 190 200 210 220
800 810 820 830 840 850
pF1KE9 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
: :::::::: ::: ...:...::.. ...:::::. .: : : : . .:. :::
XP_005 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
230 240 250 260 270 280
860 870 880 890 900 910
pF1KE9 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
: :: :: . .::... : : .. : .. .::::::.:... . .. .:: :. :
XP_005 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
290 300 310 320 330 340
920 930 940 950 960 970
pF1KE9 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
::::.: . :..:: . . ::. ::.:::::::::::::::: :. ::.:.:::
XP_005 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
350 360 370 380 390 400
980 990 1000 1010 1020 1030
pF1KE9 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
:::::::: . :.:.: . :. :.. ...::. :... :: :: ::.::..
XP_005 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
410 420 430 440 450
1040 1050 1060 1070 1080 1090
pF1KE9 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
:::. . .: : .: . :.: :::::: . .. ...:. ....... : . .
XP_005 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
460 470 480 490 500
1100 1110 1120 1130 1140 1150
pF1KE9 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
. . .: :.: ..:. .::.. .:. . . :.. :... ......
XP_005 EKLTPLK------------LIDSWMGKGAAKLRVAGVVA--PTLPREDLEKIIAHFLIQQ
510 520 530 540 550
1160 1170 1180 1190 1200 1210
pF1KE9 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
: :: ..: .:.:. .: ::. .::.. .. :.. .:. :... :. ::
XP_005 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
560 570 580 590 600
1220 1230 1240 1250 1260 1270
pF1KE9 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
XP_005 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
610 620 630 640
1417 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:33:16 2016 done: Sun Nov 6 06:33:19 2016
Total Scan time: 15.730 Total Display time: 0.540
Function used was FASTA [36.3.4 Apr, 2011]