Result of FASTA (omim) for
pFN21AE9626
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9626, 860 aa
1>>>pF1KE9626 860 - 860 aa - 860 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1885+/-0.00043; mu= 15.6653+/- 0.027
mean_var=71.3906+/-14.176, 0's: 0 Z-trim(110.5): 56 B-trim: 8 in 1/51
Lambda= 0.151794
statistics sampled from 18862 (18913) to 18862 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.573), E-opt: 0.2 (0.222), width: 16
Scan time: 11.000
The best scores are: opt bits E(85289)
XP_005270632 (OMIM: 607355) PREDICTED: protein arg ( 860) 5863 1293.9 0
NP_079128 (OMIM: 607355) protein argonaute-3 isofo ( 860) 5863 1293.9 0
XP_016856012 (OMIM: 607355) PREDICTED: protein arg ( 860) 5863 1293.9 0
XP_011539181 (OMIM: 607355) PREDICTED: protein arg ( 845) 5764 1272.2 0
XP_011539538 (OMIM: 606228) PREDICTED: protein arg ( 860) 4993 1103.3 0
NP_036331 (OMIM: 606228) protein argonaute-1 isofo ( 857) 4508 997.1 0
NP_001304051 (OMIM: 606228) protein argonaute-1 is ( 891) 4508 997.1 0
NP_001304052 (OMIM: 606228) protein argonaute-1 is ( 782) 4488 992.7 0
XP_016856505 (OMIM: 606228) PREDICTED: protein arg ( 876) 4351 962.7 0
XP_016856508 (OMIM: 606228) PREDICTED: protein arg ( 706) 4316 955.1 0
NP_036286 (OMIM: 606229) protein argonaute-2 isofo ( 859) 4302 952.0 0
XP_011515267 (OMIM: 606229) PREDICTED: protein arg ( 873) 4286 948.5 0
XP_011515270 (OMIM: 606229) PREDICTED: protein arg ( 918) 4285 948.3 0
XP_011515268 (OMIM: 606229) PREDICTED: protein arg ( 813) 4281 947.4 0
XP_016868806 (OMIM: 606229) PREDICTED: protein arg ( 782) 4271 945.2 0
XP_016856014 (OMIM: 607355) PREDICTED: protein arg ( 626) 4252 941.0 0
XP_016856013 (OMIM: 607355) PREDICTED: protein arg ( 626) 4252 941.0 0
XP_016856015 (OMIM: 607355) PREDICTED: protein arg ( 626) 4252 941.0 0
XP_011539184 (OMIM: 607355) PREDICTED: protein arg ( 626) 4252 941.0 0
XP_016856016 (OMIM: 607355) PREDICTED: protein arg ( 626) 4252 941.0 0
NP_803171 (OMIM: 607355) protein argonaute-3 isofo ( 626) 4252 941.0 0
XP_005270633 (OMIM: 607355) PREDICTED: protein arg ( 585) 3970 879.3 0
XP_016856017 (OMIM: 607355) PREDICTED: protein arg ( 585) 3970 879.3 0
XP_016856506 (OMIM: 606228) PREDICTED: protein arg ( 873) 3866 856.5 0
XP_016856507 (OMIM: 606228) PREDICTED: protein arg ( 725) 3658 811.0 0
NP_060099 (OMIM: 607356) protein argonaute-4 [Homo ( 861) 3501 776.6 0
NP_001158095 (OMIM: 606229) protein argonaute-2 is ( 825) 3428 760.6 0
XP_005270635 (OMIM: 607356) PREDICTED: protein arg ( 794) 3196 709.8 1.2e-203
XP_005270636 (OMIM: 607356) PREDICTED: protein arg ( 794) 3196 709.8 1.2e-203
XP_011539185 (OMIM: 607356) PREDICTED: protein arg ( 711) 2844 632.7 1.8e-180
XP_011539186 (OMIM: 607356) PREDICTED: protein arg ( 660) 2528 563.5 1.1e-159
XP_016856018 (OMIM: 607356) PREDICTED: protein arg ( 378) 1467 331.1 5.9e-90
NP_001177900 (OMIM: 605571) piwi-like protein 1 is ( 829) 462 111.1 2.2e-23
XP_016875718 (OMIM: 605571) PREDICTED: piwi-like p ( 832) 462 111.1 2.2e-23
XP_011537308 (OMIM: 605571) PREDICTED: piwi-like p ( 481) 450 108.4 8.2e-23
NP_004755 (OMIM: 605571) piwi-like protein 1 isofo ( 861) 450 108.5 1.4e-22
XP_011537306 (OMIM: 605571) PREDICTED: piwi-like p ( 861) 450 108.5 1.4e-22
XP_011537305 (OMIM: 605571) PREDICTED: piwi-like p ( 861) 450 108.5 1.4e-22
XP_011537304 (OMIM: 605571) PREDICTED: piwi-like p ( 861) 450 108.5 1.4e-22
NP_001129193 (OMIM: 610312) piwi-like protein 2 is ( 973) 421 102.1 1.3e-20
NP_060538 (OMIM: 610312) piwi-like protein 2 isofo ( 973) 421 102.1 1.3e-20
NP_001008496 (OMIM: 610314) piwi-like protein 3 is ( 882) 412 100.1 4.6e-20
NP_001242904 (OMIM: 610314) piwi-like protein 3 is ( 873) 384 94.0 3.2e-18
NP_689644 (OMIM: 610315) piwi-like protein 4 [Homo ( 852) 383 93.8 3.7e-18
NP_001317409 (OMIM: 610312) piwi-like protein 2 is ( 937) 346 85.7 1.1e-15
XP_005273608 (OMIM: 610312) PREDICTED: piwi-like p ( 804) 247 64.0 3.2e-09
XP_011537307 (OMIM: 605571) PREDICTED: piwi-like p ( 819) 213 56.6 5.7e-07
>>XP_005270632 (OMIM: 607355) PREDICTED: protein argonau (860 aa)
initn: 5863 init1: 5863 opt: 5863 Z-score: 6932.8 bits: 1293.9 E(85289): 0
Smith-Waterman score: 5863; 100.0% identity (100.0% similar) in 860 aa overlap (1-860:1-860)
10 20 30 40 50 60
pF1KE9 MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
790 800 810 820 830 840
850 860
pF1KE9 QALAKAVQIHQDTLRTMYFA
::::::::::::::::::::
XP_005 QALAKAVQIHQDTLRTMYFA
850 860
>>NP_079128 (OMIM: 607355) protein argonaute-3 isoform a (860 aa)
initn: 5863 init1: 5863 opt: 5863 Z-score: 6932.8 bits: 1293.9 E(85289): 0
Smith-Waterman score: 5863; 100.0% identity (100.0% similar) in 860 aa overlap (1-860:1-860)
10 20 30 40 50 60
pF1KE9 MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
790 800 810 820 830 840
850 860
pF1KE9 QALAKAVQIHQDTLRTMYFA
::::::::::::::::::::
NP_079 QALAKAVQIHQDTLRTMYFA
850 860
>>XP_016856012 (OMIM: 607355) PREDICTED: protein argonau (860 aa)
initn: 5863 init1: 5863 opt: 5863 Z-score: 6932.8 bits: 1293.9 E(85289): 0
Smith-Waterman score: 5863; 100.0% identity (100.0% similar) in 860 aa overlap (1-860:1-860)
10 20 30 40 50 60
pF1KE9 MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
790 800 810 820 830 840
850 860
pF1KE9 QALAKAVQIHQDTLRTMYFA
::::::::::::::::::::
XP_016 QALAKAVQIHQDTLRTMYFA
850 860
>>XP_011539181 (OMIM: 607355) PREDICTED: protein argonau (845 aa)
initn: 5764 init1: 5764 opt: 5764 Z-score: 6815.7 bits: 1272.2 E(85289): 0
Smith-Waterman score: 5764; 100.0% identity (100.0% similar) in 845 aa overlap (16-860:1-845)
10 20 30 40 50 60
pF1KE9 MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPR
10 20 30 40
70 80 90 100 110 120
pF1KE9 RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGR
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE9 NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDN
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE9 QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE9 YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE9 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTL
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE9 LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE9 HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRF
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE9 KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCAD
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE9 RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE9 QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDP
770 780 790 800 810 820
850 860
pF1KE9 QALAKAVQIHQDTLRTMYFA
::::::::::::::::::::
XP_011 QALAKAVQIHQDTLRTMYFA
830 840
>>XP_011539538 (OMIM: 606228) PREDICTED: protein argonau (860 aa)
initn: 3318 init1: 2772 opt: 4993 Z-score: 5903.1 bits: 1103.3 E(85289): 0
Smith-Waterman score: 4993; 83.8% identity (94.2% similar) in 869 aa overlap (1-860:1-860)
10 20 30 40 50
pF1KE9 MEIGSAGPA-GA-----QPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIK
:: : .: : :: : ....::::: ::.::::::::: :.:.::::::: ::::::
XP_011 MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 PDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGE
:::::::::::::. :::::: :::::.::::::...::.. ::... ::..::.:::
XP_011 PDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 GGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMK
: ::: ::::::... :::..:::.:.. .: ::: :.:.::..::: ::.
XP_011 G-KDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLE--------SVQALDVAMRHLASMR
130 140 150 160 170
180 190 200 210 220 230
pF1KE9 YTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQF
:::::::::: :::: ::::::::::::::::::::::::::::::::::::::::::.:
XP_011 YTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT
:::::::.::::::.:::::.::.:::::::::::::::: :.:::::::::::::::::
XP_011 MCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
::::::.::::: ::::::..::.::::::::::::::::::::::::::::::::::::
XP_011 FPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL
:::::::::::::::::::::::::::::...:.:. ::..::: .::.:.:..::::::
XP_011 KKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 PAPMLQYGGR---NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGF
:::.:::::: ::..:::..::::::::::..:.:::.::::::: :.:::::.::.:
XP_011 PAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNF
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 TDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYA
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE9 EVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQP
::::::::::::::::::::::.:::::::::::::::::::::::::::::: .:::::
XP_011 EVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQP
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE9 VIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELL
:::::::::::::::::::::.:::::::::::::::::::::::::::.::. ::::::
XP_011 VIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELL
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE9 IQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKR
::::::::::::::::::::: :::. :.:.:::::::.:::.:::::::::::::::::
XP_011 IQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKR
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE9 HHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWD
:::::::::..::.:.::::::::::::.::::.:::::::::::::::::::::.::::
XP_011 HHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWD
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE9 DNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHV
:: :::::::.:::::::::::::::::::::::::.:::::::::::::::::.::::.
XP_011 DNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHI
780 790 800 810 820 830
840 850 860
pF1KE9 SGQSNGRDPQALAKAVQIHQDTLRTMYFA
:::::::::::::::::.:::::::::::
XP_011 SGQSNGRDPQALAKAVQVHQDTLRTMYFA
840 850 860
>>NP_036331 (OMIM: 606228) protein argonaute-1 isoform 1 (857 aa)
initn: 4900 init1: 4386 opt: 4508 Z-score: 5329.1 bits: 997.1 E(85289): 0
Smith-Waterman score: 5009; 84.1% identity (94.6% similar) in 866 aa overlap (1-860:1-857)
10 20 30 40 50
pF1KE9 MEIGSAGPA-GA-----QPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIK
:: : .: : :: : ....::::: ::.::::::::: :.:.::::::: ::::::
NP_036 MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 PDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGE
:::::::::::::. :::::: :::::.::::::...::.. ::... ::..::.:::
NP_036 PDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 GGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMK
: ::: ::::::... :::..:::.:.. .: ::: :.:.::..::: ::.
NP_036 G-KDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLE--------SVQALDVAMRHLASMR
130 140 150 160 170
180 190 200 210 220 230
pF1KE9 YTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQF
:::::::::: :::: ::::::::::::::::::::::::::::::::::::::::::.:
NP_036 YTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT
:::::::.::::::.:::::.::.:::::::::::::::: :.:::::::::::::::::
NP_036 MCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
::::::.::::: ::::::..::.::::::::::::::::::::::::::::::::::::
NP_036 FPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL
:::::::::::::::::::::::::::::...:.:. ::..::: .::.:.:..::::::
NP_036 KKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ
:::.::::::::..:::..::::::::::..:.:::.::::::: :.:::::.::.::::
NP_036 PAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQ
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE9 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF
:::::::::::::::::::.:::::::::::::::::::::::::::::: .::::::::
NP_036 RVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIF
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE9 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF
::::::::::::::::::.:::::::::::::::::::::::::::.::. :::::::::
NP_036 LGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQF
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE9 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT
:::::::::::::::::: :::. :.:.:::::::.:::.::::::::::::::::::::
NP_036 YKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHT
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE9 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC
::::::..::.:.::::::::::::.::::.:::::::::::::::::::::.::::::
NP_036 RLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNR
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE9 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ
:::::::.:::::::::::::::::::::::::.:::::::::::::::::.::::.:::
NP_036 FTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQ
780 790 800 810 820 830
840 850 860
pF1KE9 SNGRDPQALAKAVQIHQDTLRTMYFA
::::::::::::::.:::::::::::
NP_036 SNGRDPQALAKAVQVHQDTLRTMYFA
840 850
>>NP_001304051 (OMIM: 606228) protein argonaute-1 isofor (891 aa)
initn: 4900 init1: 4386 opt: 4508 Z-score: 5328.8 bits: 997.1 E(85289): 0
Smith-Waterman score: 5009; 84.1% identity (94.6% similar) in 866 aa overlap (1-860:1-857)
10 20 30 40 50
pF1KE9 MEIGSAGPA-GA-----QPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIK
:: : .: : :: : ....::::: ::.::::::::: :.:.::::::: ::::::
NP_001 MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 PDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGE
:::::::::::::. :::::: :::::.::::::...::.. ::... ::..::.:::
NP_001 PDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 GGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMK
: ::: ::::::... :::..:::.:.. .: ::: :.:.::..::: ::.
NP_001 G-KDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLE--------SVQALDVAMRHLASMR
130 140 150 160 170
180 190 200 210 220 230
pF1KE9 YTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQF
:::::::::: :::: ::::::::::::::::::::::::::::::::::::::::::.:
NP_001 YTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT
:::::::.::::::.:::::.::.:::::::::::::::: :.:::::::::::::::::
NP_001 MCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
::::::.::::: ::::::..::.::::::::::::::::::::::::::::::::::::
NP_001 FPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL
:::::::::::::::::::::::::::::...:.:. ::..::: .::.:.:..::::::
NP_001 KKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ
:::.::::::::..:::..::::::::::..:.:::.::::::: :.:::::.::.::::
NP_001 PAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQ
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE9 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF
:::::::::::::::::::.:::::::::::::::::::::::::::::: .::::::::
NP_001 RVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIF
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE9 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF
::::::::::::::::::.:::::::::::::::::::::::::::.::. :::::::::
NP_001 LGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQF
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE9 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT
:::::::::::::::::: :::. :.:.:::::::.:::.::::::::::::::::::::
NP_001 YKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHT
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE9 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC
::::::..::.:.::::::::::::.::::.:::::::::::::::::::::.::::::
NP_001 RLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNR
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE9 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ
:::::::.:::::::::::::::::::::::::.:::::::::::::::::.::::.:::
NP_001 FTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQ
780 790 800 810 820 830
840 850 860
pF1KE9 SNGRDPQALAKAVQIHQDTLRTMYFA
::::::::::::::.:::::::::::
NP_001 SNGRDPQALAKAVQVHQDTLRTMYFAXRQNAVTSLDRRKLSKPQELCHPNPEEARRREVG
840 850 860 870 880 890
>>NP_001304052 (OMIM: 606228) protein argonaute-1 isofor (782 aa)
initn: 4588 init1: 4386 opt: 4488 Z-score: 5306.1 bits: 992.7 E(85289): 0
Smith-Waterman score: 4684; 85.5% identity (95.8% similar) in 791 aa overlap (70-860:1-782)
40 50 60 70 80 90
pF1KE9 EIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLP
:::::: :::::.::::::...::.. ::
NP_001 MVQHFKPQIFGDRKPVYDGKKNIYTVTALP
10 20 30
100 110 120 130 140 150
pF1KE9 VATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNP
... ::..::.:::: ::: ::::::... :::..:::.:.. .: :::
NP_001 IGNERVDFEVTIPGEG-KDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLE--------S
40 50 60 70 80
160 170 180 190 200 210
pF1KE9 VHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNID
:.:.::..::: ::.:::::::::: :::: :::::::::::::::::::::::::::::
NP_001 VQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNID
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE9 VSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRK
:::::::::::::.::::::::.::::::.:::::.::.:::::::::::::::: :.::
NP_001 VSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRK
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE9 YRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTY
:::::::::::::::::::::.::::: ::::::..::.:::::::::::::::::::::
NP_001 YRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTY
210 220 230 240 250 260
340 350 360 370 380 390
pF1KE9 LPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQ
::::::::::::::::::::::::::::::::::::::::::::...:.:. ::..:::
NP_001 LPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFG
270 280 290 300 310 320
400 410 420 430 440 450
pF1KE9 FKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAT
.::.:.:..:::::::::.::::::::..:::..::::::::::..:.:::.:::::::
NP_001 IKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAP
330 340 350 360 370 380
460 470 480 490 500 510
pF1KE9 QRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
:.:::::.::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLI
390 400 410 420 430 440
520 530 540 550 560 570
pF1KE9 IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNIL
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_001 IVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNIL
450 460 470 480 490 500
580 590 600 610 620 630
pF1KE9 VPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEI
::::: .::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_001 VPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEI
510 520 530 540 550 560
640 650 660 670 680 690
pF1KE9 IQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDY
:.::. ::::::::::::::::::::::::::: :::. :.:.:::::::.:::.:::::
NP_001 IEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDY
570 580 590 600 610 620
700 710 720 730 740 750
pF1KE9 QPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQG
:::::::::::::::::::::..::.:.::::::::::::.::::.::::::::::::::
NP_001 QPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQG
630 640 650 660 670 680
760 770 780 790 800 810
pF1KE9 TSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV
:::::::.:::::: :::::::.:::::::::::::::::::::::::.:::::::::::
NP_001 TSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLV
690 700 710 720 730 740
820 830 840 850 860
pF1KE9 DKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
::::::.::::.:::::::::::::::::.:::::::::::
NP_001 DKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA
750 760 770 780
>>XP_016856505 (OMIM: 606228) PREDICTED: protein argonau (876 aa)
initn: 2787 init1: 2130 opt: 4351 Z-score: 5143.1 bits: 962.7 E(85289): 0
Smith-Waterman score: 4951; 82.3% identity (92.5% similar) in 885 aa overlap (1-860:1-876)
10 20 30 40 50
pF1KE9 MEIGSAGPA-GA-----QPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIK
:: : .: : :: : ....::::: ::.::::::::: :.:.::::::: ::::::
XP_016 MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 PDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGE
:::::::::::::. :::::: :::::.::::::...::.. ::... ::..::.:::
XP_016 PDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 GGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMK
: ::: ::::::... :::..:::.:.. .: ::: :.:.::..::: ::.
XP_016 G-KDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLE--------SVQALDVAMRHLASMR
130 140 150 160 170
180 190 200 210 220 230
pF1KE9 YTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQF
:::::::::: :::: ::::::::::::::::::::::::::::::::::::::::::.:
XP_016 YTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT
:::::::.::::::.:::::.::.:::::::::::::::: :.:::::::::::::::::
XP_016 MCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
::::::.::::: ::::::..::.::::::::::::::::::::::::::::::::::::
XP_016 FPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL
:::::::::::::::::::::::::::::...:.:. ::..::: .::.:.:..::::::
XP_016 KKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 PAPMLQYGGR---NRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGF
:::.:::::: ::..:::..::::::::::..:.:::.::::::: :.:::::.::.:
XP_016 PAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNF
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 TDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYA
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE9 EVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQP
::::::::::::::::::::::.:::::::::::::::::::::::::::::: .:::::
XP_016 EVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQP
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE9 VIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELL
:::::::::::::::::::::.:::::::::::::::::::::::::::.::. ::::::
XP_016 VIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELL
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE9 IQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKR
::::::::::::::::::::: :::. :.:.:::::::.:::.:::::::::::::::::
XP_016 IQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKR
660 670 680 690 700 710
720 730 740 750
pF1KE9 HHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQ-------------
:::::::::..::.:.::::::::::::.::::.:::::::::::::
XP_016 HHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQPSSLPSLGPLTFL
720 730 740 750 760 770
760 770 780 790 800 810
pF1KE9 ---GTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRAR
::::::::.:::::: :::::::.:::::::::::::::::::::::::.:::::::
XP_016 SSQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRAR
780 790 800 810 820 830
820 830 840 850 860
pF1KE9 YHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
::::::::::.::::.:::::::::::::::::.:::::::::::
XP_016 YHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA
840 850 860 870
>>XP_016856508 (OMIM: 606228) PREDICTED: protein argonau (706 aa)
initn: 4314 init1: 4314 opt: 4316 Z-score: 5103.3 bits: 955.1 E(85289): 0
Smith-Waterman score: 4316; 88.4% identity (96.7% similar) in 704 aa overlap (161-860:3-706)
140 150 160 170 180
pF1KE9 VSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSM----KYTPVGRSFFSAP
: : . : :. .:::::::::: :
XP_016 MPHRVGACARGTSSLPVPARYTPVGRSFFSPP
10 20 30
190 200 210 220 230 240
pF1KE9 EGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDE
::: ::::::::::::::::::::::::::::::::::::::::::.::::::::.::::
XP_016 EGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDE
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE9 QPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVE
::.:::::.::.:::::::::::::::: :.:::::::::::::::::::::::.:::::
XP_016 QPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVE
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE9 RTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMI
::::::..::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMI
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE9 KATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNR
:::::::::::::::::...:.:. ::..::: .::.:.:..:::::::::.::::::::
XP_016 KATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNR
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE9 TVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPI
..:::..::::::::::..:.:::.::::::: :.:::::.::.::::::::::::::::
XP_016 AIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPI
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE9 QGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQ
340 350 360 370 380 390
550 560 570 580 590 600
pF1KE9 CVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGD
:::::::.:::::::::::::::::::::::::::::: .::::::::::::::::::::
XP_016 CVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGD
400 410 420 430 440 450
610 620 630 640 650 660
pF1KE9 GKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRII
::::::.:::::::::::::::::::::::::::.::. :::::::::::::::::::::
XP_016 GKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRII
460 470 480 490 500 510
670 680 690 700 710 720
pF1KE9 FYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVG
:::::: :::. :.:.:::::::.:::.::::::::::::::::::::::::::..::.:
XP_016 FYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIG
520 530 540 550 560 570
730 740 750 760 770 780
pF1KE9 RSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQ
.::::::::::::.::::.:::::::::::::::::::::.:::::: :::::::.::::
XP_016 KSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQ
580 590 600 610 620 630
790 800 810 820 830 840
pF1KE9 LCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKA
:::::::::::::::::::::.:::::::::::::::::.::::.:::::::::::::::
XP_016 LCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKA
640 650 660 670 680 690
850 860
pF1KE9 VQIHQDTLRTMYFA
::.:::::::::::
XP_016 VQVHQDTLRTMYFA
700
860 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 14:44:14 2016 done: Mon Nov 7 14:44:16 2016
Total Scan time: 11.000 Total Display time: 0.330
Function used was FASTA [36.3.4 Apr, 2011]